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Reposted by Muriel Perron

Seth Blackshaw @sethblackshaw.bsky.social · 26d

Our latest manuscript is out, and this one tackles the problem of cellular aging in the retina, using comparative multiomic analysis of zebrafish, mouse, and humans. What led us to work on aging after studying development and regeneration? Explainer follows./1
www.biorxiv.org/content/10.1...

Comparative single-cell multiomic analysis reveals evolutionarily conserved and species-specific cellular mechanisms mediating natural retinal aging.

Biological age is a major risk factor in the development of common degenerative retinal diseases such as age-related macular degeneration and glaucoma. To systematically characterize molecular mechani...

www.biorxiv.org

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Muriel Perron @murielperron.bsky.social · Sep 6

Fantastic workshop !!!! Thank you again Seth and Michel !!!

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Juliane Glaser @julianeg.bsky.social · Sep 4

🥳 Very grateful for the support of the ERC Starting Grant for my newly established lab! We will study how transposable elements contribute to mammalian embryonic development.
We will have positions available next year. Stay tuned!

European Research Council (ERC) @erc.europa.eu · Sep 4

📣 The ERC Starting Grant call results are out!

Find out which early-career researchers will receive funding this year, what they will be investigating, where they will be based... plus lots of other #ERCStG facts & figures for 2025!

➡️ buff.ly/IsafuFh

#FrontierResearch 🇪🇺#EUfunded #HorizonEurope

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Reposted by Muriel Perron

Kara Cerveny @kara-cerveny.bsky.social · Aug 27

Come be my colleague! We are hiring for two tenure-track positions. www.reed.edu/dean_of_facu...

Tenure-Track Positions in Functional Genomics/Genetics and Systems Biology - Office of the Dean of the Faculty - Reed College

www.reed.edu

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Reposted by Muriel Perron

Developmental Biology @devbiol.bsky.social · Aug 9

Early embryonic developmental pathways are activated during regeneration phase in Xenopus 🐸
--by Aniket Kshirsagar, Rachel Ronan, Ana Lúcia Rebelo, Siobhan McMahon, Abhay Pandit, and Gerhard Schlosser

www.sciencedirect.com/science/arti...

#Xenopus #regeneration #DBfeature

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Reposted by Muriel Perron

Justin Kumar @flyeyelab.bsky.social · Aug 5

My lab's newest research paper on the Drosophila eye is published in Development today. Thanks to the editorial staff for writing a research highlight and interviewing us about our work.

journals.biologists.com/dev/article-...

Differential regulation of eye specification in Drosophila by Polycomb Group epigenetic repressors

Highlighted Article: Distinct gene sets are differentially expressed in response to the knockdown of Polycomb Group (PcG) members, suggesting that multiple avenues may exist for the eye to be transfor...

journals.biologists.com

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Muriel Perron @murielperron.bsky.social · Aug 4

Deadline approaching: 22 Aug 2025!!!
Tenure-track Junior Professor (CPJ) in Multi-omics Cell Atlases of Brain Development
@neuropsi.bsky.social @univparissaclay.bsky.social
Details: www.universite-paris-saclay.fr/sites/defaul...
Apply via ODYSSEE: odyssee.enseignementsup-recherche.gouv.fr

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Reposted by Muriel Perron

Paris-Saclay Institute of Neuroscience @neuropsi.bsky.social · Jun 28

🔬🐁 We have a new position open!

➡️ Our "Chaire Professeur Junior" position focuses on multi-omics during brain development. This research-heavy position follows a tenure-track scheme, leading to a full professor position.

🗓️ Application deadline: 22/08/2025

www.universite-paris-saclay.fr

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Reposted by Muriel Perron

Paris-Saclay Institute of Neuroscience @neuropsi.bsky.social · May 21

A tenure track "AI and pathological behavioral trajectories" Professor position is open at NeuroPSI.
Learn more and apply
🔽🔽🔽🔽🔽🔽
emploi.cnrs.fr/Offres/CPJ/C...

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Reposted by Muriel Perron

Paris-Saclay Institute of Neuroscience @neuropsi.bsky.social · May 16

Join us next Monday and Tuesday (May the 19-20) for the 2025 joint TCCI/NeuroPSI conference!

This year the conference focuses on Social cognition, Decision making & Communication.

You can still register to attend online: neuropsi-2025.sciencesconf.org

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Reposted by Muriel Perron

Xenbase @xenbase.bsky.social · May 14

Dr. Dominique Alfandari seeks requests for producing Xenopus antibodies. Fill out the form in the link to make your suggestions. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs

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Muriel Perron @murielperron.bsky.social · May 16

A Tenure-track Junior Professor Chair (CPJ) is now open at @neuropsi.bsky.social
Focus: Multi-omics cellular atlases of brain development
Application details & deadline coming soon, stay tuned!
@univparissaclay.bsky.social

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Reposted by Muriel Perron

Seth Blackshaw @sethblackshaw.bsky.social · Apr 28

The final version of our eLife manuscript on viral Oct4-mediated neurogenic reprogramming of retinal Muller glia is now out, with all reviewer comments addressed.
elifesciences.org/reviewed-pre...

Viral-mediated Oct4 overexpression and inhibition of Notch signaling synergistically induce neurogenic competence in mammalian Müller glia

elifesciences.org

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Reposted by Muriel Perron

Seth Blackshaw @sethblackshaw.bsky.social · Apr 29

Our latest manuscript (7 years in the works) tackles the question of how diurnal ground squirrels evolved a cone-dominant retina, in contrast to the ancestral rod-dominant retina retained by virtually all other mammals./1
www.biorxiv.org/content/10.1...

Heterochronic transcription factor expression drives cone-dominant retina development in 13-lined ground squirrels.

Evolutionary adaptation to diurnal vision in ground squirrels has led to the development of a cone-dominant retina, in stark contrast to the rod-dominant retinas of most mammals. The molecular mechani...

www.biorxiv.org

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Reposted by Muriel Perron

Seth Blackshaw @sethblackshaw.bsky.social · Apr 5

Our latest manuscript on glia-to-neuron conversion in retina is out in @elife.bsky.social. We show that AAV-mediated overexpression of Oct4 induces glia-to-bipolar cell conversion in wildtype retina, and that this is greatly enhanced by loss of function of Rbpj.

elifesciences.org/reviewed-pre...

Viral-mediated Oct4 overexpression and inhibition of Notch signaling synergistically induce neurogenic competence in mammalian Müller glia

elifesciences.org

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Muriel Perron @murielperron.bsky.social · Mar 18

The Paris-Saclay Institute of Neuroscience @neuropsi.bsky.social has launched a call for new group leaders. Please spread the word!
deadline May 30
neuropsi.cnrs.fr/wp-content/u...
@cnrs.fr @univparissaclay.bsky.social

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Reposted by Muriel Perron

Paris-Saclay Institute of Neuroscience @neuropsi.bsky.social · Feb 18

Le programme de la semaine du cerveau se précise. Toute la semaine du 10 mars, NeuroPSI et NeuroSPIN vous accueillent à tour de rôle pour une série de conférences et d'animation à destination de tous les publics !
neuropsi.cnrs.fr/semaine-cerv...

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Reposted by Muriel Perron

Paris-Saclay Institute of Neuroscience @neuropsi.bsky.social · Feb 25

▶️ The 2025 TCCI-NeuroPSI conference will take place on May 19-20 at NeuroPSI.

▶️ Dive with us into the dynamic interactions between social cognition, emotions and communication systems, which enable adaptive choices in complex social environments!

▶️ Register: neuropsi-2025.sciencesconf.org

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Seth Blackshaw @sethblackshaw.bsky.social · Feb 25

Our new review article with @michelcayouette.bsky.social is out on temporal patterning and glial reprogramming in adult CNS, and its implications for treating degenerative diseases. All work from our lab discussed here was funded by NIH.
authors.elsevier.com/a/1kfup3Q9h2...

authors.elsevier.com

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Michel Cayouette @michelcayouette.bsky.social · Feb 25

Happy to share this review that @sethblackshaw.bsky.social and I wrote about temporal patterning and how these mechanisms could be coaxed to stimulate glia reprogramming and CNS regeneration! Access link below, feel free to use the figures in your talks!😊
authors.elsevier.com/c/1kfup3Q9h2...

authors.elsevier.com

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Reposted by Muriel Perron

Ryan MacDonald @macdonaldlab.bsky.social · Feb 7

We’re hiring a new research fellow. Come join us in London to study glial cells in the ageing retina using killifish as a model. www.ucl.ac.uk/work-at-ucl/...

UCL – University College London

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

www.ucl.ac.uk

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Seth Blackshaw @sethblackshaw.bsky.social · Jan 27

Introducing MetaLigand, our latest collaboration with the Qian group, a database for predicting non-peptide ligand mediated cell-cell signaling.

www.biorxiv.org/content/10.1...

MetaLigand: A database for predicting non-peptide ligand mediated cell-cell communication

Non-peptide ligands (NPLs), including lipids, amino acids, carbohydrates, and non-peptide neurotransmitters and hormones, play a critical role in ligand-receptor-mediated cell-cell communication, driv...

www.biorxiv.org

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Muriel Perron @murielperron.bsky.social · Jan 29

The correct version of our paper in ScienceAdvances is now live on PubMed! (Yes, our entire Figure 3 had been mysteriously swapped… but it's all fixed now!)
It is about the complex role of inflammation in Müller glia response to injury. science.org/doi/10.1126/...
@neuropsi.bsky.social

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Reposted by Muriel Perron

Paris-Saclay Institute of Neuroscience @neuropsi.bsky.social · Jan 24

🐁 Découvrez notre animalerie et certaines des recherches qui y sont menées dans cette nouvelle video de la série "Les visites du GIRCOR"!

"À la découverte de nos différences grâce aux souris" - Les visites du Gircor

YouTube video by Gircor

youtu.be

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Reposted by Muriel Perron

Paris-Saclay Institute of Neuroscience @neuropsi.bsky.social · Jan 24

🗓️ La prochaine Semaine du Cerveau c'est du 10 au 14 mars prochain.

🧠Rejoignez-nous à NeuroPSI, en partenariat avec Neurospin et @cea-joliot.bsky.social, pour de nombreuses conférences et animations!

Suivez-nous ici pour en savoir bientôt davantage...

Semaine du Cerveau 2025 - Institut des Neurosciences Paris‑Saclay

La Semaine du cerveau 2025 est organisée conjointement par NeuroSpin (Institut Joliot) et par l'Institut NeuroPSI. Programme prévisionnel du 10 au 14 mars 2025 Pour la deuxième année consécutive, la...

neuropsi.cnrs.fr

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