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Reposted by Olivier Pertz

Lucien Hinderling @lhinderling.bsky.social · 7d

Want to get started with smart microscopy? 🧠🔬
Check out our online repository with implementations from labs and industry -- lots of practical tips and links to sample code! smartmicroscopy.github.io/implementati...

More details in the ✨updated preprint!✨
www.biorxiv.org/content/10.1...

screenshots of some of the sample implementations

Screenshot of smartmicroscopy.github.io/implementations.html, showing an overview of collected implementation examples

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Mark Peifer (He, him) @peiferlabunc.bsky.social · 15d

Cell and developmental biologists; This is well worth a read: Maik and Roberto synthesize work over decades to propose a provocative model of who mesenchymal cells migrate and shape tissues 🧪 Go for the cool Figures, stay for the deep insights

Rockefeller University Press @rupress.org · 15d

New perspective in @jcb.org by @maikbischoff.bsky.social & @mayorlab.bsky.social about how mesenchymal cells use contact-dependent rules to generate swarm-like behaviors, patterns & organ forms. rupress.org/jcb/article/...

#CellBio #CellMigration #Morphogenesis #Development #Science

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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 24d

Its raining #Ichthyos ... Hallelujah!

#Lattice #LightSheet #Ichthyosporeans #Creolimax #Cellularization #ProtistsOnSky

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Olivier Pertz @olivierpertz.bsky.social · 28d

so happy to have Katie as a colleague !

Germán Orizaola @gorizaola.bsky.social · 29d

Nice interview to Katie Peichel @currentbiology.bsky.social

I completely agree with her claims for more funding for curiosity-driven research, basic Science... Science.

www.cell.com/current-biol...

Catherine Peichel

Interview with Katie Peichel, who studies the evolutionary genetics of sticklebacks at the University of Bern, Switzerland.

www.cell.com

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Germán Orizaola @gorizaola.bsky.social · 29d

Nice interview to Katie Peichel @currentbiology.bsky.social

I completely agree with her claims for more funding for curiosity-driven research, basic Science... Science.

www.cell.com/current-biol...

Catherine Peichel

Interview with Katie Peichel, who studies the evolutionary genetics of sticklebacks at the University of Bern, Switzerland.

www.cell.com

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Olivier Pertz @olivierpertz.bsky.social · 29d

looks like an ingenious combination of technologies to study out of equilibrium developmental processes ... Congrats !

Ina Sonnen @sonnenlab.bsky.social · 29d

Preprint alert!
We combined microfluidics, proteomics, and RNA-seq to map spatiotemporal protein expression during mouse somitogenesis and found a novel regulatory strategy: dynamic antagonistic gradients fine-tune signalling strength.

doi.org/10.1101/2025...

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Olivier Pertz @olivierpertz.bsky.social · 29d

⚡️ Don’t forget that we’re looking for a Tenure-track Assistant Professor in Quantitative Cell Biology @ UniBern!

🔬 Bridge experiments + theory
📈 Tackle processes across scales
💡 Join our vibrant research community

Deadline Oct 17 👉 shorturl.at/1Y1WP

Assistant Professor with tenure-track for Quantitative Cell Biology (80-100%) - Bern, Switzerland job with University of Bern, Institute of Cell Biology | 12840798

Assistant Professor with tenure-track for Quantitative Cell Biology (80-100%) at the University of Bern, Switzerland.

shorturl.at

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Levayer Lab @levayerr.bsky.social · Aug 28

Summer break prevented me from properly advertising this serie of reviews on the function of cell death during development that I edited. There is still a lot to dig in regarding regulation of apoptosis in vivo ad I hope we managed to illustrate this well
www.sciencedirect.com/special-issu...

Seminars in Cell & Developmental Biology | Novel functions of programmed cell death in development: current status and future challenges | ScienceDirect.com by Elsevier

While the core regulators of programmed cell death have been relatively well characterised, our understanding of the regulation and role of programmed cell death in tissue during embryonic development...

www.sciencedirect.com

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Systems Biology Ireland @sysbioire.bsky.social · Aug 27

2 weeks ago we were some of the first to see 'Cancer Revolution: Science, Innovation & Hope,' the astounding new exhibition from Breakthrough Cancer Research. Read more about this free interactive display & our involvement in the project along w/ @precisiononcire.bsky.social

ucd.ie/sbi/news/new...

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Olivier Pertz @olivierpertz.bsky.social · Aug 22

“New paper out 🎉 We built a system to automate optogenetic cell control across scales. For the demo, we made the cells spell my name — because if you can’t use science to feed your ego, what’s the point? 😎🧫✨”

Lucien Hinderling @lhinderling.bsky.social · Aug 21

Automated optogenetic control of hundreds of cells in parallel. Each cell is individually steered, collectively acting as a "tissue printer". Preprint & code out! www.biorxiv.org/content/10.1...

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Lucien Hinderling @lhinderling.bsky.social · Aug 21

Automated optogenetic control of hundreds of cells in parallel. Each cell is individually steered, collectively acting as a "tissue printer". Preprint & code out! www.biorxiv.org/content/10.1...

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Olivier Pertz @olivierpertz.bsky.social · Aug 22

Congrats @lhinderling.bsky.social and team

Lucien Hinderling @lhinderling.bsky.social · Aug 21

So many people involved! Special thanks to @hannah-superres.bsky.social, Alfredo Rates, @olivierpertz.bsky.social, @nilsnorlin.bsky.social, Aliaksandr Halavatyi & Rafael Camacho. Link again to the paper: www.biorxiv.org/content/10.1...

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Reposted by Olivier Pertz

Lucien Hinderling @lhinderling.bsky.social · Aug 21

So many people involved! Special thanks to @hannah-superres.bsky.social, Alfredo Rates, @olivierpertz.bsky.social, @nilsnorlin.bsky.social, Aliaksandr Halavatyi & Rafael Camacho. Link again to the paper: www.biorxiv.org/content/10.1...

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Lucien Hinderling @lhinderling.bsky.social · Aug 21

Not only acquisition settings can be changed, but also perturbation: Popular is automated targeting of photomanipulation:

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Lucien Hinderling @lhinderling.bsky.social · Aug 21

For example event-driven acquisition: rare events (here mitoses) are detected in a low-res overview scan, the microscope switches objective to automatically image only the mitotic cells in high-res. 🔎

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Lucien Hinderling @lhinderling.bsky.social · Aug 21

🔬🧠 Our paper on smart microscopy & the issue of interoperability! www.biorxiv.org/content/10.1... LONG THREAD WARNING: Smart microscopy uses real-time image analysis to automatically guide the acquisition or perturbation of the sample (closed feedback-control loop). Many applications exist:

Figure legend: Categories and capabilities of smart microscopy systems integrating real-time image analysis and feedback control. Top: Smart microscopy workflows can be classified based on the driving logic behind decision-making: Event-driven (reacting to rare biological events), Outcome-driven (using feedback-control to steer biological systems toward a desired state), Quality-driven (optimizing signal quality or imaging metrics), and Information-driven (guided by models that predict which measurements/perturbations will yield the most informative data). Middle: Central feedback loop between the microscope and an image analysis system, which continuously
exchanges images and commands to guide acquisition dynamically. Bottom: Key control actions enabled by smart microscopy: adjusting imaging modality (e.g. switching from brightfield to fluorescence, adjusting sampling rate), repositioning the field of view (e.g. tracking, drift correction), optimizing acquisition settings (e.g. adaptive optics),
and performing photomanipulation (e.g. FRAP, ablation, optogenetics).

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Lab on a Chip @labonachip.rsc.org · Aug 6

In the latest issue of Lab on a Chip:
Teach your microscope how to print: low-cost and rapid-iteration microfabrication for biology.
#OpenAccess from Olivier Pertz, Lucien Hinderling et al @olivierpertz.bsky.social @lhinderling.bsky.social‬.
Read now: pubs.rsc.org/en/content/a...

Teach your microscope how to print: low-cost and rapid-iteration microfabrication for biology

The application of traditional microfabrication techniques to biological research is hindered by their reliance on clean rooms, expensive or toxic materials, and slow iteration cycles. We present an a...

pubs.rsc.org

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Pau Formosa-Jordan @pauformosa.bsky.social · Aug 4

Introducing five concepts from dynamical systems to decode developmental regulatory mechanisms, have a read! @perez-carrasco.bsky.social‬ @roederlab.bsky.social @mpipz.bsky.social This effort started in a morphogenesis meeting @kitp-ucsb.bsky.social‬ in 2023. journals.biologists.com/dev/article/...

Adapted from Fig. 1 from Kadiyala et al 2025.

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Fusion Conferences @fusionconf.bsky.social · Aug 4

@lwellberg.bsky.social @josjonkers.bsky.social @olivierpertz.bsky.social @juliosaezrod.bsky.social
please share with your followers - thank you!

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Olivier Pertz @olivierpertz.bsky.social · Aug 1

Thanks for having me !

Nils Blüthgen @molsysbio.bsky.social · Aug 1

Happy to chair a session on cell and pathway engineering at ICSB2025.com featuring e.g. an inspiring talk by @olivierpertz.bsky.social on pathway dynamics, cell fates and optical tools. Contributed talk deadline is today, Sept 1st for poster abstracts. Hope to see you in Dublin in October! #ICSB2025

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Lucien Hinderling @lhinderling.bsky.social · Jul 26

first data from the new LLSM in PertzLab @olivierpertz.bsky.social! i always thought nuclei were spherical but they are pancakes???? so much more to see in 3d, but data volume produced is insane, we will have to rethink our analysis pipelines. tips welcome! here shown in @napari.org

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Silas Maniatis @manimota.bsky.social · Jul 16

Loved the preprint, congrats on the paper!

Lucien Hinderling @lhinderling.bsky.social · Jul 16

PAPER OUT ✨ What if you could use your microscope as a 3D printer? Prototype microfluidics in-house, <5$ in material costs per chip. From idea to experiment within a day. Now published in Lab-on-a-Chip (open-access): doi.org/10.1039/D5LC...

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Pau Guillamat @pauguillamat.bsky.social · Jun 30

New preprint out! We show how cellular nematic order can be harnessed to program tissue-wide force fields and guide 3D shape transformations.

The tissue morphogenesis logic, now engineered into living, programmable materials.

www.biorxiv.org/content/10.1...

#ActiveMatter #TissueEngineering

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Joachim Goedhart @joachimgoedhart.bsky.social · Jun 27

I'm honored - writing blogs for @the-node.bsky.social‬ has been a fabulous experience and thanks to y'all for reading and amplifying
bsky.app/profile/biol...

The Company of Biologists @biologists.bsky.social · Jun 25

This week, we are featuring Joachim Goedhart, one of the most prolific authors on @the-node.bsky.social, as an extraordinary biologist. #100biologists
@joachimgoedhart.bsky.social

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Olivier Pertz @olivierpertz.bsky.social · Jun 25

@lhinderling.bsky.social just defended his PhD with highest honors! 🌟 From code to cells, he blends computation + biology like few can. Proud to have supervised such a brilliant scientist. Watch out—Lucien’s going far! 🚀
#PhDDefense #QuantBio #CellBiology #RisingStar

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