Vikram Paralkar
@paralkarlab.bsky.social
2.5K followers
770 following
510 posts
Physician-Scientist | University of Pennsylvania | Pol I, rRNA, Ribosomes, Chromatin, Transcription | Hematopoiesis and Leukemia | 🩸🔬🧪🧬
https://paralkarlab.med.upenn.edu
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Chris Hayes
@chrislhayes.bsky.social
· Jul 18
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Teif lab
@teiflab.bsky.social
· 24d
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Vikram Paralkar
@paralkarlab.bsky.social
· Aug 31
Vikram Paralkar
@paralkarlab.bsky.social
· Aug 28
Vikram Paralkar
@paralkarlab.bsky.social
· Aug 28
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Craig Kaplan
@triggerloop.bsky.social
· Aug 28
Widespread epistasis shapes RNA polymerase II active site function and evolution - Nature Communications
The active site of RNA Polymerase II is highly conserved. Here the authors show that mutations can propagate effects across the enzyme and alter genetic behavior of distal residues, demonstrating plas...
www.nature.com