Integrating sex as a biological variable in bioengineering should not be viewed as a women’s health concern but as a requirement for reproducible, rigorous research that ultimately benefits everyone. ...

With this cross-journal Collection, the editors invite manuscripts that highlight recent advances in understanding the fate, transport, and effects of ...

Nature Reviews Endocrinology, Published online: 16 January 2026; doi:10.1038/s41574-026-01231-2GPR110 as a regulator of MASH

Nature Microbiology, Published online: 16 January 2026; doi:10.1038/s41564-025-02239-6A library of 400 phage protein-coding genes is used to find a trove of antiphage systems, revealing systems that target tail fibre and major capsid proteins.

It's our name, and it's what our team members are doing. With every step they take, every mile they run, they're helping to make our vision a reality: a world where sustainability is as integral to a...

Universities are in thrall to a rankings system that prioritizes narrow aspects of academic life. Three changes would give institutions the freedom to explore fresh ways of working.

Nature Reviews Neurology, Published online: 13 November 2025; doi:10.1038/s41582-025-01159-7Genome-wide association studies have identified genetic modifiers, mostly DNA repair genes, that significantly influence the onset and progression of Huntington disease, pointing to somatic CAG repeat expansions as a key pathological driver. Here, Tabrizi and colleagues review the evidence for this paradigm and discuss the potential for therapeutic interventions.

Nature Reviews Clinical Oncology, Published online: 11 November 2025; doi:10.1038/s41571-025-01085-zThird-generation EGFR tyrosine kinase inhibitors such as osimertinib have substantially improved clinical outcomes in advanced-stage EGFR-mutant non-small-cell lung cancer, but resistance remains inevitable. In this Review, the authors discuss biomarker-directed and biomarker-unselected approaches to overcome established resistance to osimertinib, as well as pre-emptive upfront strategies to delay or prevent the occurrence of osimertinib resistance.

Cancer prevention vaccines have reduced cancer-related mortalities, yet therapeutic cancer vaccine development and clinical translation continues to face challenges. Here, Zaidi, Jaffee and Yarchoan summarize the failures of cancer vaccines of the past, to highlight recent advancements in the field.

Muscle samples from over 120 people were analyzed to identify molecular patterns linked to insulin resistance, a key feature of type 2 diabetes. The findings reveal new insights that could help tailor more personalized and effective treatments for the disease.