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Reposted by Alexander Price

Mandy Muller @mandymuller.bsky.social · 2d

🧬 Exciting news from our lab 🧬 The Swiss National Science Foundation (SNSF) has approved our project studying KSHV and RNA decay: our first grant since re-launching the lab in Switzerland 🎉 We’re now looking for a Postdoc and a PhD student to join the team (start date January 2026) - please repost!

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Reposted by Alexander Price

Emmanuelle Genoyer @immunuelle.bsky.social · 5d

I'm thrilled to announce I'll be joining the Department of Molecular Genetics & Microbiology at the University of Florida in January 2026! My lab will study RNA virus-host interactions with a particular focus on the spatial regulation of viral replication and innate immune activation. genoyerlab.com

Genoyer Lab

genoyerlab.com

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Alexander Price @pricelesssci.bsky.social · 5d

Amazing and congrats! They are a great department down there!

Alexander Price @pricelesssci.bsky.social · 22d

This work was led by Claire O'Brien, our amazing Research Assistant who has learned every molecular virology technique under the sun in putting this together. I bring it up because she is applying for grad schools this fall and would be an amazing addition to any program!

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Alexander Price @pricelesssci.bsky.social · 22d

We believe these tools will be useful to adenovirologists, as well as those that simply use this powerful little virus as a vector. In the manuscript we demonstrate using the E4 region for multicistronic gene expression, as well as a single vector system for doxycycline-induced gene expression.

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Alexander Price @pricelesssci.bsky.social · 22d

Using the amazing AdenoBuilder system we have constructed a set of fluorescent and bioluminescent Ad5 viruses. By exploiting the existing transcriptional units of the virus, our single color and dual color (early/late) reporters reflect the staging of the virus with wildtype replication kinetics.

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Alexander Price @pricelesssci.bsky.social · 22d

Very excited to share the first publication from the Price Lab, "Replication-competent adenovirus reporters utilizing endogenous viral expression architecture", is now online at Journal of Virology!
journals.asm.org/doi/10.1128/...

Replication-competent adenovirus reporters utilizing endogenous viral expression architecture | Journal of Virology

This research provides powerful new tools to rapidly study adenovirus gene expression and replication. By integrating fluorescent and secreted luciferase reporters into native viral regulatory element...

journals.asm.org

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Reposted by Alexander Price

Lena Steckelberg @lenasteckelberg.bsky.social · Sep 4

So excited to see our newest study out in print! Led by the brilliant @jgezelle.bsky.social and @sophiekorn.bsky.social, we discovered how viruses from highly divergent families converge on a shared RNA structure mechanism to inhibit cellular nucleases. #RNAsky #LoveVirology

Jeanine Gezelle @jgezelle.bsky.social · Sep 2

Our study from the Steckelberg lab is out now in @narjournal.bsky.social !! We dove into a new nuclease-blocking viral #RNA structure important for viral infection, which provided evidence of similar structure-based strategies across diverse viral families. academic.oup.com/nar/article/...

A conserved viral RNA fold enables nuclease resistance across kingdoms of life

Abstract. Viral exoribonuclease-resistant RNA (xrRNA) structures block cellular nucleases to produce subgenomic viral RNAs during infection. High sequence

academic.oup.com

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Alexander Price @pricelesssci.bsky.social · Aug 20

First ever Price Lab paper accepted this morning!!! Hopefully follow-up post soon to showcase our new systems.

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Zach Weinersmith @zachweinersmith.bsky.social · Jul 27

Stats: www.smbc-comics.com/comic/number...

(also you can buy the mug and other smbc stuff here: smbc-store.myshopify.com/products/goo...)

#smbc

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Alexander Price @pricelesssci.bsky.social · Jul 28

The 20 years of sneezes to the face is what sent me, but every panel has a line that makes me laugh!

Zach Weinersmith @zachweinersmith.bsky.social · Jul 26

Immune

Full comic here: www.smbc-comics.com/comic/lesson

#smbc

Reposted by Alexander Price

Claudia Mimoso @camimoso.bsky.social · Jul 14

Excited to share that our latest story on Restrictor is out now in @genesdev.bsky.social!! Big thank you to my fellow co-first author Hanneke, Karen @adelmanlab.bsky.social and co-authors Nathalie and Allison!

Genes & Development @genesdev.bsky.social · Jul 10

In this study, Mimoso et al. show that Restrictor serves as a transcriptional safeguard that suppresses the spurious transcription of non-coding RNAs, while preserving mRNA transcription.

Learn more here:
➡️ tinyurl.com/gd352654

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Reposted by Alexander Price

Tempera_Lab @itphilly.bsky.social · Jul 13

We are excited to share our recent work:
EBNA leader protein orchestrates chromatin architecture remodeling during Epstein-Barr virus-induced B cell transformation url: academic.oup.com/nar/article/...

EBNA leader protein orchestrates chromatin architecture remodeling during Epstein-Barr virus-induced B cell transformation

Abstract. Epstein-Barr virus Nuclear Antigen Leader Protein (EBNA-LP) plays a pivotal role in the transformation of B cells by Epstein-Barr virus (EBV), fu

academic.oup.com

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Alexander Price @pricelesssci.bsky.social · Jul 11

Also serial numbers of random equipment!

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Alexander Price @pricelesssci.bsky.social · Jul 3

The Price Lab turned two years old this week! Of course we celebrated with cake, but the cherry on top was submitting our labs very first manuscript today! Excited to see what the rest of the year holds.

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Reposted by Alexander Price

Avgousti lab @avgoustilab.bsky.social · Jun 26

Postdoc positions available! Please re-post!

Are you interested in how viruses manipulate chromatin? Are you excited to discover unknown facets of molecular biology? If so, we’d love to hear from you! Come check us out at:
avgoustilab.org

Avgousti Lab

Investigating viral manipulation of host chromatin dynamics

avgoustilab.org

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Reposted by Alexander Price

Christin Herrmann @christinviral.bsky.social · Jun 25

Excited to share with you my postdoctoral work published today in Nature Microbiology!

www.nature.com/articles/s41...

We have known for a while that stress can impact the outcome of infectious diseases; however, we reveal in our paper that it is not always detrimental.

Environmental stress drives clearance of a persistent enteric virus in mice - Nature Microbiology

Cage change of mice with persistent murine astrovirus infection triggers stress responses marked by corticosterone fluctuation, which is followed by CD8 T cell activation and induction of epithelial a...

www.nature.com

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Reposted by Alexander Price

Nature Microbiology @natmicrobiol.nature.com · Jun 25

#NewResearch

🚨Out now!

Environmental stress drives clearance of a persistent enteric virus in mice 🐀
@christinviral.bsky.social @cadwelllab.bsky.social

#MicroSky #VirusSky

www.nature.com/articles/s41...

Environmental stress drives clearance of a persistent enteric virus in mice - Nature Microbiology

Cage change of mice with persistent murine astrovirus infection triggers stress responses marked by corticosterone fluctuation, which is followed by CD8 T cell activation and induction of epithelial a...

www.nature.com

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Alexander Price @pricelesssci.bsky.social · Jun 16

My then 2 year old said "it means daddy dropped something", right after using it in perfect context when she dropped a crayon. Little information sponges...

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Reposted by Alexander Price

🌀Olliebeanzmom🌀 @olliebeanzmom.bsky.social · Jun 14

Love Park in Philly today for the No Kings protest 👏👏👏

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Dr. Lucky Tran @luckytran.com · Jun 14

#NoKings protest in Philadelphia

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Shannon Righi @shannonrighi.bsky.social · Jun 6

Excited to share our editorial on peer review, out now in #mBio! This was a mighty group effort with my mBio Early Career Editorial Board peer mentoring group
@proctordm.bsky.social and Rachy Abraham.

From novice to expert: preparing your peer review | mBio journals.asm.org/doi/10.1128/...

From novice to expert: preparing your peer review | mBio

Peer review is the process that academic journals, conferences, and funding agencies use to ensure the quality of scholarly work before it is published, presented, or funded. Reviewers for academic jo...

journals.asm.org

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Reposted by Alexander Price

Thelonevirologist @thelonevirologist.bsky.social · Jun 4

Gammaherpesvirus infection triggers the formation of tRNA fragments from premature tRNAs journals.asm.org/doi/10.1128/...

Gammaherpesvirus infection triggers the formation of tRNA fragments from premature tRNAs | mBio

Diverse conditions of infection and cellular stress incite the cleavage of transfer RNAs (tRNAs), leading to the formation of tRNA fragments (tRFs) that can directly regulate gene expression. In our s...

journals.asm.org

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Alexander Price @pricelesssci.bsky.social · Jun 3

Yes! We bought a starter kit during the end of the pandemic but for various reasons never got around to using it. This first one operated like a charm, but a second expired one failed to reach 37C. Analyzing the data now to see if it's actually useable.

Alexander Price @pricelesssci.bsky.social · May 30

I also thought the experience was rather painless, but our grad student (who made this slide for our following lab meeting) had different opinions?

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