Lightnews — Scholar-powered news

Rakyan Lab @rakyanlab.bsky.social · 17h

Well done!

Alex de Mendoza @alexdemendoza.bsky.social · 17h

Thrilled to share that the lab has been awarded a @wellcometrust.bsky.social Discovery Award to keep exploring the evolution of 6-methyladenine #6mA in Eukaryotes. We'll open postdoc (3️⃣) and tech (1️⃣) positions to start in 2026, please share with candidates or reach out if you’d like to join us.

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Rakyan Lab @rakyanlab.bsky.social · 3d

Woah!

store.steampowered.com/app/4045010/...

Meowtabolism - Examining Feline Behavior within Unicellular Algae on Steam

Explore the interior of an algal cell on your four paws. Built with experimental data and populated with actual protein structures, Meowtabolism offers a glimpse of the vast world inside the basic fun...

store.steampowered.com

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Rakyan Lab @rakyanlab.bsky.social · 5d

One of my scientific heroes.

journals.biologists.com/dev/article/...

An interview with Azim Surani

Professor Azim Surani is the Director of Epigenomics and Germline Imprinting at the Gurdon Institute in Cambridge, UK. He is this year's recipient of both the prestigious Kyoto Prize and the Paul Ehrl...

journals.biologists.com

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Rakyan Lab @rakyanlab.bsky.social · 7d

www.bbc.co.uk/news/live/c9...

'An extraordinary legacy': Tributes after chimpanzee expert Jane Goodall dies age 91 - follow live

The primatologist was a

www.bbc.co.uk

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Reposted by Rakyan Lab

Jeremie Kalfon 👨‍💻🧬🤖🚀 @jkobject.com · 13d

The first 1 million prime numbers vizualized in 2D according to their prime factors (Umap)

Source: johnhw.github.io/uma...

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Reposted by Rakyan Lab

Adam Phillippy @aphillippy.bsky.social · 14d

🚂 The T2T train keeps rolling: "The formation and propagation of human Robertsonian chromosomes" with Gerton and Garrison labs is out! What's a Robertsonian chromosome? Let Jen tell you herself in this great video, or read our paper: [1/3]
📺 youtu.be/JmlY5omxQVc
📄 www.nature.com/articles/s41...

How Stowers Scientists Found the DNA Site Where Robertsonian Chromosomes Fuse

YouTube video by Stowers Institute for Medical Research

youtu.be

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Rakyan Lab @rakyanlab.bsky.social · 14d

Lovely work!

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Reposted by Rakyan Lab

Tom Clark @tom-clark.bsky.social · 15d

Useful reminder from Peter Kellner on the problems we refuse to acknowledge are getting better, and the politics of hopelessness that this breeds

open.substack.com/pub/kellnerp...

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Rakyan Lab @rakyanlab.bsky.social · 16d

Awesome!

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Adam Phillippy @aphillippy.bsky.social · 16d

Delighted to finally announce a preprint describing the Q100 project! “A complete diploid human genome benchmark for personalized genomics” For which we finished HG002 to near-perfect accuracy: www.biorxiv.org/content/10.1... 🧵[1/14]

A complete diploid human genome benchmark for personalized genomics

Human genome resequencing typically involves mapping reads to a reference genome to call variants; however, this approach suffers from both technical and reference biases, leaving many duplicated and ...

www.biorxiv.org

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Rakyan Lab @rakyanlab.bsky.social · 24d

🤯

NBC10 Boston @nbcboston.com · 27d

Brent Chapman can see again after doctors pulled out one of his teeth, flattened it, drilled a hole in it, placed a lens inside and implanted the tooth in one of his eyes. on.nbcboston.com/mRI06Sh

Man, 34, is no longer blind after tooth is implanted in eye in 'crazy' surgery

Tooth-in-eye surgery sounds like science fiction, but it can help people with severely damaged corneas see again. A patient and his doctors describe what it's like.

on.nbcboston.com

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Reposted by Rakyan Lab

Trevor Graham @trevorgraham.bsky.social · 28d

Studying cancer evolution needs multi-region or single cell seq for phylogenetics, right? Amazingly (I think!) we found single-sample bulk methylation suffices, via analysis of "fluctuating methylation". In @nature.com today led by brilliant @calumgabbutt.bsky.social www.nature.com/articles/s41...

Fluctuating DNA methylation tracks cancer evolution at clinical scale - Nature

Cancer evolutionary dynamics are quantitatively inferred using a method, EVOFLUx, applied to fluctuating DNA methylation.

www.nature.com

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Rakyan Lab @rakyanlab.bsky.social · Sep 3

🤯

www.nature.com/articles/s41...

One mother for two species via obligate cross-species cloning in ants - Nature

In a case of obligate cross-species cloning, female ants of Messor ibericus need to clone males of Messor structor to obtain sperm for producing the worker caste, resulting in males from the same moth...

www.nature.com

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Rakyan Lab @rakyanlab.bsky.social · Aug 28

I’m most definitely a ‘mellow’ guy!

Nature @nature.com · Aug 28

It's five o'clock somewhere

go.nature.com/4mHORlC

Beer lovers fall into two flavour camps — which one are you in?

Research shows that beer drinkers are split depending on which types of flavour chemicals they prefer.

go.nature.com

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Reposted by Rakyan Lab

Sergey Melnikov @sergeymelnikov.bsky.social · Jun 19

Here, we show that bacterial ribosomes—often viewed as conserved drug targets—actually vary across species due to extensive sequence variation in their drug-binding residues. In some cases, this divergence may lead to intrinsic drug resistance in certain bacterial clades: doi.org/10.1016/j.ce...

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Reposted by Rakyan Lab

Robert Seaborne @robertseaborne.bsky.social · Aug 13

Very happy to have been awarded a NIRG from the MRC. Stay tuned for some exciting (I think, but being biased) postdoc positions within our lab!

King's Faculty of Life Sciences & Medicine @kingslsm.bsky.social · Aug 13

Congratulations to Dr Robert Seaborne @kingscollegelondon.bsky.social who has been awarded a New Investigator Grant from the Medical Research Council (MRC), which will support his work on understanding the role of skeletal muscle in motor neurone disease.
Read more ➡️ www.kcl.ac.uk/news/dr-robe...

Photo of Dr Robert Seaborne with quote: "The support from the MRC will allow our lab to apply novel methodologies that we have developed over the last ~5 years, to study motor neurone disease from a muscle perspective, giving us a greater opportunity to provide novel insights into the disease."

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Rakyan Lab @rakyanlab.bsky.social · Aug 23

Well done Rob!!

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Reposted by Rakyan Lab

The Royal Society @royalsociety.org · Aug 20

#OnThisDay in 1858, a seminal journal article comprised of papers by Alfred Russel Wallace FRS and Charles Darwin FRS on the theory of evolution by natural selection was published by the Linnean Society, the first public announcement of the theory of evolution. bit.ly/3k8fq4u

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Reposted by Rakyan Lab

Kurianlab @kurianlab.bsky.social · Aug 7

www.nature.com/articles/s41...

A programmed decline in ribosome levels governs human early neurodevelopment - Nature Cell Biology

Ni, Wei, Vona and colleagues use human brain organoids to dissect patient AIRIM variants associated with neurodevelopmental features. A subset of variants impaired ribosome production and protein synt...

www.nature.com

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Reposted by Rakyan Lab

Moose Allain @mooseallain.bsky.social · Aug 6

www.worldofmoose.com/products/fez...

Fez Cartoon

This cartoon is an original, signed ink drawing by Moose Allain

www.worldofmoose.com

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Rakyan Lab @rakyanlab.bsky.social · Aug 4

For what it is worth, I had the same problem with an overload of US politics when I first started using BlueSky. But after a few months, I was able to sufficiently refine my list of people to follow so that now I get very little US politics popping up.

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Rakyan Lab @rakyanlab.bsky.social · Aug 2

Beautiful work.

Vikram Paralkar @paralkarlab.bsky.social · Aug 2

📣 New preprint 📣

We present a detailed map of nascent and mature ribosomal RNAs in mouse hematopoiesis and AML (including absolute rRNA molecule numbers), and outline principles of rDNA regulation.

Work by Eleanor Sams (@eleanor44.bsky.social) & Victoria Feist (@victoriafeist.bsky.social). (1/x)

Dynamics of Ribosomal RNA Transcription and Abundance in Normal and Leukemic Hematopoiesis

Transcription of ribosomal RNAs (rRNAs) from rDNA repeats is the first step of ribosome biogenesis, accounting for a major portion of all cellular transcription. Often regarded as a housekeeping proce...

www.biorxiv.org

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Rakyan Lab @rakyanlab.bsky.social · Aug 2

Very nice!

Ahmad Jomaa @jomaalab.bsky.social · Aug 1

Check out our new preprint on the discovery of a molecular switch in NAC that mediates nascent chain sorting on the ribosome and prevents mitochondrial protein mistargeting by SRP. A great collaboration with the Shan Lab @Caltech and the Qi Lab @UVA: www.biorxiv.org/content/10.1...

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Rakyan Lab @rakyanlab.bsky.social · Jul 31

Just submitted a large grant application. Getting funding these days is so difficult that even a acknowledgement of receipt counts as a win! 😅

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Rakyan Lab @rakyanlab.bsky.social · Jul 30

Oh I see. And it will be difficult via their German distributor too? We had a similar issue (not RNA ladder) for a US product, but were able to easily procure it from their European distributor.

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