Lightnews — Scholar-powered news

RAPP OptoElectronic @rappopto.bsky.social · Sep 4

Beautiful pictures—thanks for sharing, @kasiagrochowska.bsky.social

Congratulations again on the new system. It's great to see that it's being put into action so quickly and successfully.

We look forward to more great pictures in the future ;)

Grochowska lab (SynPro) @kasiagrochowska.bsky.social · Sep 2

The beauty of these images will never stop amazimg me. Hippocampal (CA1) neurons expressing an artificial cytoplasmic protein partially targeted to lysosomes (black dots).

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RAPP OptoElectronic @rappopto.bsky.social · Sep 1

@rappopto.bsky.social was more than happy to support such an incredible meeting.

Martin Brill @martinbrill.bsky.social · Sep 1

Grateful to have had the chance to connect to many old friends and to make new ones at the incredible "Bee and Fly Neuroethology Meeting" at the Harnack house of the @maxplanck.de in Berlin.
The energy around new discoveries and brilliant scientists was infectious, and inspiring.

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RAPP OptoElectronic @rappopto.bsky.social · Aug 22

We're proud that the FRAP technology from @rappopto.bsky.social supported this discovery by enabling high-resolution analysis of condensate dynamics.

Congrats to the authors @annaleder.bsky.social and others of the Hiller Lab University of Basel

HillerLab @hillerlab.bsky.social · Aug 11

New paper alert! Stellar work by brilliant lead first author @annaleder.bsky.social together with project leader @masgu.bsky.social reveals a groundbreaking discovery: PDIA6 forms multi-chaperone condensates creating "folding factories" in the ER. www.nature.com/articles/s41...

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RAPP OptoElectronic @rappopto.bsky.social · Aug 18

It was a splendid time with @kasiagrochowska.bsky.social and Long Yan from Florida Lifetime Imaging.

It’s been a great pleasure working together - thank you @kasiagrochowska.bsky.social and the team for the fruitful collaboration!

All the best for terrific data and exciting endeavors to come 🙌

Grochowska lab (SynPro) @kasiagrochowska.bsky.social · Aug 15

Exciting week with calibration of the FLIM module!

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RAPP OptoElectronic @rappopto.bsky.social · Aug 6

Wonderful work by @viji-draviam.bsky.social and team.
Congratulations on the publication!

We're honored to be cited in your work—exciting to see our contributions supporting cutting-edge research. Looking forward to following your continued discoveries!

Viji Draviam @viji-draviam.bsky.social · Aug 6

FRAP-SR (60 nm) reveals subcompartments within DNA damage repair foci in live cells. FRAP in the Super-resolution regime is likely to transform many other fields of cell biology: www.cell.com/cell-reports.... Thanks to @rappopto.bsky.social, @carlzeissstiftung.bsky.social and @ukri.org for support.

Fluorescence recovery in the super-resolution regime reveals subcompartments of 53BP1 foci

Wu et al. exploit 60 nm lateral resolution of diSIM/SIM2-processed super-resolution (SR) images to develop FRAP in the SR regime, which reveals distinct types of DNA-damage-repair-associated 53BP1 foc...

www.cell.com

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RAPP OptoElectronic @rappopto.bsky.social · Aug 4

New insights: Muscles grow by splitting sarcomeres! 💥 Using our UGA-42 #photomanipulation, the authors showed sarcomeres divide under tension to stay functional during development.

Congrats to all authors on a beautiful scientific paper!

Frank Schnorrer @frankschnorrer.bsky.social · Jul 10

SARCOMERES divide! Mechanism how muscles grow while contracting - daughter sarcomeres appear everywhere. Seen live, registered on our cover. Pioneered by @clementrodier.bsky.social @friedrich-group.bsky.social Ian Estabrook @ibdm.bsky.social $ by @hfspo.bsky.social www.science.org/doi/10.1126/...

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RAPP OptoElectronic @rappopto.bsky.social · Jul 24

A beautiful new paper about IP3 Uncaging with the UGA-42 system:

Endothelial cells pass signals by triggering receptors on neighbors—not through gap junctions.
A new way vessels stay in sync!

by Buckley, Zhang, Lee, Wilson & McCarron 2025 FASEB

faseb.onlinelibrary.wiley.com/doi/10.1096/...

faseb.onlinelibrary.wiley.com

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RAPP OptoElectronic @rappopto.bsky.social · Jun 27

Did you miss the talk by @swarnck.bsky.social from @rappopto.bsky.social at the #laserworldofphotonics in Munich yesterday?

Visit him at the Chroma booth B2.446!
And talk #photomanipulation

Zain Ali, Georg Draude, Almut Bailly (all Chroma GmbH), Melissa (89North Inc.) & @swarnck.bsky.social

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Reposted by RAPP OptoElectronic

Sven Warnck @swarnck.bsky.social · Jun 17

I'm thrilled to announce that I've been invited to give a talk on the #Biophotonics and Medical Applications Forum (B2.350) at #LASER World-of-Photonics in #Munich.
Come by on June 26, 2025, from 10:40 to 11:00 to hear about the "Latest Applications in Fast and Precise #Photomanipulation".

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RAPP OptoElectronic @rappopto.bsky.social · Jun 5

Come say hello at our joint booth at #ELMI2025

There's some great coffee and beer to celebrate 25 years of @eurobioimaging.bsky.social

Just walk up the helix and grab yours.

We're happy to chat

Toptica
Chroma
@microscopy.confocalnl.com
@ultimeyes.bsky.social by CAIRN
&
@rappopto.bsky.social

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Reposted by RAPP OptoElectronic

Sven Warnck @swarnck.bsky.social · Jun 4

Come say hello at our joint booth at #ELMI2025 — there's some great coffee and beer there to celebrate 25 years of #ELMI! Just walk up the helix and grab yours.

We're happy to chat.

RAPP OptoElectronic @rappopto.bsky.social · May 30

ELMI @eulimi.bsky.social turns 25 next week – and we’re bringing cake (if the mouse leaves us any)...

See you at the 25th European Light Microscopy Initiative meeting at @embl.org w/ our friends Toptica, @microscopy.confocalnl.com, @ultimeyes.bsky.social by CAIRN GmbH, and Chroma Technology Corp.

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RAPP OptoElectronic @rappopto.bsky.social · May 30

ELMI @eulimi.bsky.social turns 25 next week – and we’re bringing cake (if the mouse leaves us any)...

See you at the 25th European Light Microscopy Initiative meeting at @embl.org w/ our friends Toptica, @microscopy.confocalnl.com, @ultimeyes.bsky.social by CAIRN GmbH, and Chroma Technology Corp.

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Reposted by RAPP OptoElectronic

Viji Draviam @viji-draviam.bsky.social · May 8

FRAP-in-SR for dynamic studies at 60nm resolution!! If you explore cell cycle, DNA damage or 53BP1, here are new tools for live-cell microscopy: a fruitful collaboration with @carlzeissstiftung.bsky.social for SIM2/diSIM and @rappopto.bsky.social for localised FRAP www.biorxiv.org/content/10.1...

FRAP-in-SR: Fluorescence recovery in the Super-Resolution regime reveals subcompartments of 53BP1 foci

We combine Lattice Structured Illumination Microscopy (diSIM/SIM2 with ~60 nm resolution), Lattice Light-sheet microscopy and Fluorescence Recovery After Photobleaching (FRAP) to explore 53BP1 dynamic...

www.biorxiv.org

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RAPP OptoElectronic @rappopto.bsky.social · May 8

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A stunning new paper from Deqing Kong & the Jörg Großhans lab dives deep into how cells change shape and reorganize during development. Their toolkit? Precision light from
@rappopto.bsky.social
And we’re thrilled our lasers played a key role.

www.cell.com/current-biol...

Synchronization in epithelial tissue morphogenesis

Richa et al. demonstrate that Tmc, a mechano-gated channel in vertebrate hearing, synchronizes cell dynamics in the epithelial amnioserosa of Drosophila embryos. Experimental data together with a data...

www.cell.com

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RAPP OptoElectronic @rappopto.bsky.social · May 8

2/2 The study explores how localized Ca²⁺ signaling influences cellular dynamics using @rappopto.bsky.social 375 nm laser, and the Caliburn laser for microsurgical ablation of cell junctions - offering high spatial and temporal control.
Congrats to all authors involved.

www.cell.com/current-biol...

Synchronization in epithelial tissue morphogenesis

Richa et al. demonstrate that Tmc, a mechano-gated channel in vertebrate hearing, synchronizes cell dynamics in the epithelial amnioserosa of Drosophila embryos. Experimental data together with a data...

www.cell.com

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RAPP OptoElectronic @rappopto.bsky.social · Apr 15

Welcome to our booth at #FOM2025

We are happy to talk to you about optical filters, laser illuminations, instrumentation for #photomanipulation, the openFrame microscope, and accessories.

Many thanks to Chroma Technology and 89North for hosting us.

Rapp OptoElectronic GmbH
Cairn Research LTd

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RAPP OptoElectronic @rappopto.bsky.social · Apr 10

Our CEO @swarnck.bsky.social is experiencing the Chinese Cell Biology Community at #CSCB2025 in Zhuai.

He made new friends & e.g. saw the new Zeiss LSM Lightfield 4D.

Special thanks are due to our local partners & hosts Echo Li from Chroma Technologies and Siyuan Feng from Evident Scientific.

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RAPP OptoElectronic @rappopto.bsky.social · Apr 3

Today, we were part of the Girls' and Boys' Day,
the “Girls' and Boys' Future Day”

A program to support stereotype-free career and study choices for all.

The pupils successfully completed the day with happiness and full of motivation, thanks to a great team @rappopto.bsky.social

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RAPP OptoElectronic @rappopto.bsky.social · Apr 1

Our Applications Specialist Anja Zimmermann is on a tour with Jan Dolzer from our US-Partner Sutter Instrument @sutterinstrument.bsky.social.

On tour, Jan is giving a talk about "What is hidden under the noise" today at
@biodip.bsky.social
@crtd-tud.bsky.social
@cmcb-tud.bsky.social

👍👍

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RAPP OptoElectronic @rappopto.bsky.social · Mar 26

#NWG2025 @neurowissg.bsky.social in Göttingen has started!

We are looking forward to talking to you.
Come by and take a look at our booth 39.

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RAPP OptoElectronic @rappopto.bsky.social · Mar 18

@gerbi-gmb.de #TiM2025 in Münsingen is in full swing.

Iliya Stoev @kit.edu introducing #FLUCS photomanipulation to #TiM2025 participants.

We send our appreciation and thanks to Iliya, Britta Schroth-Diez @mpi-cbg.de, @mpi-cbg-lmf.bsky.social and Ines Höfer from Evident Scientific for support.

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Reposted by RAPP OptoElectronic

Sven Warnck @swarnck.bsky.social · Mar 12

I'm thrilled to be presenting workshops on #FLUCS with our partners, Britta and Iliya. See you there!

German BioImaging @gerbi-gmb.de · Mar 10

Only 7 days left until #TiM2025! 🎉 We're super hyped! 🚀
Don't miss out – day tickets are still available! Grab yours now and join us for an unforgettable TiM! 🙌🔥

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RAPP OptoElectronic @rappopto.bsky.social · Mar 16

Great preview of of our #FLUCS workshop next week #TIM2025 from @gerbi-gmb.de

Our CEO @swarnck.bsky.social and founder Gert Rapp as well as Simona Stelea are looking forward to meeting you there

Lennart Hilbert @lennarthilbert.bsky.social · Mar 13

Iliya Stoev showing us some impromptu FLUCS action on our new install from Rapp Optoelectronics, while prepping for a workshop with Rapp next week. Accompanied by our incoming tenure-track colleague Miha Modic
@paraspeckle.bsky.social and his student Jona Novljan

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RAPP OptoElectronic @rappopto.bsky.social · Mar 16

The countdown is on! Just one day left until #TiM2025
@gerbi-gmb.de

Thanks to our great partners in the workshops, you have the chance to dive deeper into the #FLUCS universe #photomanipulation and experience the latest functionality to make your samples move as you want to.

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RAPP OptoElectronic @rappopto.bsky.social · Feb 27

WOW absolutely stunning movies and excellent ablation approaches!

Congratulations to @micromotility.bsky.social and group as well as @jekely.biologists.social.ap.brid.gy for an amazing showcase of the precision ablation using the caliburn system from @rappopto.bsky.social.

Kirsty Wan @micromotility.bsky.social · Feb 14

New preprint from Rebecca's PhD! did you know that the ciliary band metachronal wave in #Platynereis is a series of tiny waves within each multiciliated cell! What happens if you ablate some cilia?? 🌊😱
Cool #cilia collab w/ @jekely.biologists.social.ap.brid.gy!

Revealed here doi.org/10.1101/2025...

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