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RentmeisterLab

@rentmeisterlab.bsky.social

520 followers 650 following 28 posts

Researcher in Chemical Biology, Professor at LMU Munich https://www.rentmeister-group.com/ Foto: LC Productions

www.rentmeister-group.com

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RentmeisterLab @rentmeisterlab.bsky.social · Aug 4

Thanks @stephanhacker2.bsky.social ! Very happy to see our photocaged dinucleoside tetraphosphates published. Congrats to the entire team!

Stephan Hacker @stephanhacker2.bsky.social · Jul 29

Interesting paper by the group of @rentmeisterlab.bsky.social in @chemistryeurope.bsky.social. They describe photocaged guanosine-based dinucleotide tetraphosphates like m7Gp4G and their characteristics as RNA cap analogs. chemistry-europe.onl...

Photocaged Dinucleoside Tetraphosphates for Light‐Mediated Activation of 5′ Cap Interactions and Translation In Vitro

Photocaged dinucleoside tetraphosphates can be incorporated into mRNA by T7 RNA polymerase. Subsequent irradiation with light activates 5′ cap interactions and translation. These 5′ cap analogs are u...

chemistry-europe.onlinelibrary.wiley.com

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RentmeisterLab @rentmeisterlab.bsky.social · 29d

Very much looking forward to this session highlighting SAM-dependent chemistry! 🤩 My first time at the Irsee Natural Product Symposium 😊

FOR5596 - SAM-dependent enzyme chemistry @for5596.bsky.social · Sep 8

We are organizing a session on SAM-dependent enzymes at the 38th Irsee Natural Product Symposium, February 25-27, 2026. We are pleased to welcome the following speakers:
Prof. Andrea Rentmeister, Prof. Jörg Pietruszka, and Prof. Andreas Kirschning.

Please spread the news and join us in Irsee!

RentmeisterLab @rentmeisterlab.bsky.social · Aug 7

Very proud of my PhD students Wiebke Teich and Bayram Terzi, who explain their latest paper in this interview. #proudPI 🤩

ChemistryViews @chemistryviews.bsky.social · Aug 7

💬 🧪 Behind the Science Interview with B. Terzi and W. Teich (@rentmeisterlab.bsky.social LMU Munich): Light-Activated mRNA Cap Analogs Allow Timed Control of mRNA Translation
Their work is published in @ChemistryEur - flagship journal of @ChemEurope
www.chemistryviews.org/light-activa...

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RentmeisterLab @rentmeisterlab.bsky.social · Aug 4

Thanks @stephanhacker2.bsky.social ! Very happy to see our photocaged dinucleoside tetraphosphates published. Congrats to the entire team!

Stephan Hacker @stephanhacker2.bsky.social · Jul 29

Photocaged Dinucleoside Tetraphosphates for Light‐Mediated Activation of 5′ Cap Interactions and Translation In Vitro

chemistry-europe.onlinelibrary.wiley.com

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RentmeisterLab @rentmeisterlab.bsky.social · Jul 14

Great talk by Ronald Micura about Challenges in biological RNA chemistry @lmumuenchen.bsky.social 😀

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RentmeisterLab @rentmeisterlab.bsky.social · Jul 10

Great work by @nicocorn.bsky.social - congratulations! 👍 Happy we could contribute a little bit. 😊

Nicolas Cornelissen @nicocorn.bsky.social · Jul 10

We systematically studied the substrate preferences of EbPPK2, determined the first crystal structure of the enzyme and used structure-guided engineering to enable efficient access to base-modified GTP and ATP analogues. #ChemSky #ChemBio

pubs.rsc.org/en/content/a...

We determined the first crystal structure of the polyphosphate kinase 2 class III from Erysipelotrichaceae bacterium and used structure-guided engineering to enable efficient access to nucleobase-modified GTP and ATP analogues.

RentmeisterLab @rentmeisterlab.bsky.social · Jul 8

Great workshop of @angewandtechemie.bsky.social and @gdch.de today @lmumuenchen.bsky.social.Thanks for opening the editor's blackbox and the wonderful networking opportunity! 😊🙏

RentmeisterLab @rentmeisterlab.bsky.social · Jul 7

Reminder for everyone currently in Munich area: Workshop tomorrow (Tue, July 08, 2025) by @angewandtechemie.bsky.social at @lmumuenchen.bsky.social. Please join! 🤩

RentmeisterLab @rentmeisterlab.bsky.social · Jul 1

We are looking forward to hosting @angewandtechemie.bsky.social at @lmumuenchen.bsky.social next week. Please spread the news and join us for this fantastic event! #chembio #chemsky #chemistry

RentmeisterLab @rentmeisterlab.bsky.social · Jul 1

We are looking forward to hosting @angewandtechemie.bsky.social at @lmumuenchen.bsky.social next week. Please spread the news and join us for this fantastic event! #chembio #chemsky #chemistry

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RentmeisterLab @rentmeisterlab.bsky.social · Jun 30

Our latest article is now published in @ChemicalScience
🤩 We use light-mediated activation of translation of Cas9-mRNAfor gene editing with spatio-temporal control ⚡️🧬🧪🧫
pubs.rsc.org/en/content/a...

pubs.rsc.org

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RentmeisterLab @rentmeisterlab.bsky.social · Jun 11

Enjoying the science & interactions at #SCNAC2025 😊 Thanks for the very nice foto 🙏

Michael Booth @drmikebooth.bsky.social · Jun 10

What do you call a group of nucleic acid chemists?

Suggestions welcome 🧬❤️

#SCNAC2025
@cjserpell.bsky.social @hoeferlab.bsky.social @boekhovenlab.bsky.social @rentmeisterlab.bsky.social @kgoepfrich.bsky.social @chlab.bsky.social

Picture of a lot of us nucleic acid chemists in cesky krumlov

Reposted by RentmeisterLab

GDCh Division of Biochemistry @gdchbiochem.bsky.social · May 28

If you are interested in #Biochemistry, #ChemBio and the related disciplines, already mark your calendars for the @gdchbiochem.bsky.social Conference in Würzburg on March 16th to 18th, 2026.
@gdch.de #chemsky
www.gdch.de/veranstaltun...

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Reposted by RentmeisterLab

Zebrafish Rock! @zebrafishrock.bsky.social · May 25

#DanioDigest (April 2025)

Community News:

Prof Wendy Bickmore @wbickmor.bsky.social elected as an International Member of the US National Academy of Sciences (NAS).

Prof Dr Andrea Rentmeister @rentmeisterlab.bsky.social receives 2024 Franco-German Georg Wittig - Victor Grignard Prize. (1/46)

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Reposted by RentmeisterLab

Ben Schumann @drglycoben.bsky.social · May 23

🔥 Exciting online, free #chembio event on 28th May!!

Please join us online for the hybrid ESBOC Satellite meeting! Setup as a teaser to allow for accessibility and see some of the speakers that will attend ESBOC in Gregynog/Wales. To attend, please register by sending an email: lnkd.in/e-U7C6Jb

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RentmeisterLab @rentmeisterlab.bsky.social · May 22

Thrilled to learn that the excellence cluster NUCLEATE will be funded 😃, and proud to be part of it. Congratulations to the coordinators and all contributers 👏👍

Deutsche Forschungsgemeinschaft @dfg.de · May 22

Die #Exzellenzcluster stehen fest: Heute hat die Exzellenzkommission 70 Projekte zur Förderung ausgewählt. 45 Cluster werden fortgesetzt, 25 neu eingerichtet. Die Förderung beginnt ab 1. Jan. 2026 für 7 Jahre, die Fördersumme beträgt insg. 539 Mio. €/Jahr. Die Liste: www.dfg.de/resource/blo... 1/3

Deutschlandkarte der Verteilung der Exzellenzcluster auf Bundesländer und Universitäten.

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Reposted by RentmeisterLab

Michael Wagner @michiwagner4.bsky.social · May 16

Increased ERC funding for top global researchers moving to Europe now confirmed

#Enlightenment #Facts #ProtectScience 🧪

erc.europa.eu/news-events/...

Increased ERC funding for top global researchers moving to Europe now confirmed

The European Research Council (ERC) decision to increase its support for leading researchers moving to Europe has today been formally adopted. On top of its standard grants, the ERC offers additional ...

erc.europa.eu

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RentmeisterLab @rentmeisterlab.bsky.social · May 14

Thanks for having me! 🙏

Reposted by RentmeisterLab

George Burslem @gburslem.bsky.social · May 1

Excited to see this out in @science.org today!! www.science.org/doi/10.1126/...

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RentmeisterLab @rentmeisterlab.bsky.social · Apr 30

Merci beaucoup! 🤩

RentmeisterLab @rentmeisterlab.bsky.social · Apr 30

Thank you! It is the French-German Award, and I agree, they gave it a great name 😊

RentmeisterLab @rentmeisterlab.bsky.social · Apr 30

It was an honour to give a talk today in the historic lecture hall of Université Paris Cité, Faculté de Pharmacie after receiving the Wittig-Grignard Award yesterday. Thank you very much Bruno Sargueil and Mélanie Ethève-Quelquejeu for the invitation 🤩

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Reposted by RentmeisterLab

FOR5596 - SAM-dependent enzyme chemistry @for5596.bsky.social · Apr 17

Congratulations to all the authors of this paper, which just ranked in the top 10% of the most viewed papers published in ChemBioChem in 2023! We are very excited to be able to build on this amazing work in our FOR5596 research group.

@andexerlab.bsky.social @rentmeisterlab.bsky.social

Biomimetic S‐Adenosylmethionine Regeneration Starting from Multiple Byproducts Enables Biocatalytic Alkylation with Radical SAM Enzymes**

The biomimetic regeneration system for S-adenosylmethionine (SAM) and SAM analogues presented is based on the salvage of the adenine moiety and in situ supply of d-ribose and polyphosphate. It is com...

chemistry-europe.onlinelibrary.wiley.com

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RentmeisterLab @rentmeisterlab.bsky.social · Apr 15

Come join our team! We have an opening for a research associate ("Ratsstelle"). Expertise in nucleotide chemistry and LC-MS is required. 👉 job-portal.lmu.de/jobposting/b... Deadline for application is June 01, 2025.

Research associate (Ratsstelle) for the duration of 5 years with the option to be tenured (m/f/x)

job-portal.lmu.de

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RentmeisterLab @rentmeisterlab.bsky.social · Apr 10

And here is the LMU press release for our article in Chem: www.lmu.de/en/newsroom/...

Organic syntheses: new chemistry challenges dogma

LMU researchers have developed a novel cofactor that broadens the use of methyltransferases – with great potential for research and applications.

www.lmu.de

RentmeisterLab @rentmeisterlab.bsky.social · Apr 9

Ever wondered why prenylation and methylation use different cofactor scaffolds? We now show that the SAM scaffold enables both: Chimeric cofactors enable methyltransferase-catalyzed prenylation: Chem www.cell.com/chem/fulltex... Kudos to @nicocorn.bsky.social & Arne Hoffmann and all authors 👌👏🤩

Chimeric cofactors enable methyltransferase-catalyzed prenylation

In nature, many methyltransferases (C1) use S-adenosyl-l-methionine (AdoMet or SAM) as a cofactor for methyl transfer, whereas prenyltransferases (C5) use dimethylallyl diphosphate (DMAPP). We enginee...

www.cell.com

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RentmeisterLab @rentmeisterlab.bsky.social · Apr 4

Congratulations to Dr. Katja Hartstock and Dr. Helena Schepers who successfully defended their PhD theses today. 👏🥂 So proud of my last two PhD students in Münster. 🤩All the best!