rodrisanchez95.bsky.social
Rodrigo Sánchez Martínez
@rodrisanchez95.bsky.social
130 followers 220 following 14 posts
PhD University of Alicante. Postdoc at @tum.de studying phage-host interactions in the gut. Viruses, microbial ecology, cycling, beer and more.
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rodrisanchez95.bsky.social
Rodrigo Sánchez Martínez @rodrisanchez95.bsky.social · 28d
🦠➡️🧬 Community context matters!
In the second part of my PhD, we show how microbial complexity drives phage–bacteria ecology & evolution.
Check out the preprint 👇🏼
biorxiv-microbiol.bsky.social
bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 28d
Biological context modulates virus-host dynamics and diversification https://www.biorxiv.org/content/10.1101/2025.09.10.675297v1
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Reposted by Rodrigo Sánchez Martínez
erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 6d
How exercise promotes the immune system vs cancer, working through a gut bacteria metabolite
www.cell.com/cell/abstrac...
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Reposted by Rodrigo Sánchez Martínez
ethz.ch
ETH Zurich @ethz.ch · 13d
It is not only antibiotics but also certain viruses – known as bacteriophages – that can kill off pathogenic bacteria. However, Switzerland lacks the legal framework for the use of these viruses in therapy. What would need to change? Researcher Alexander Harms explains.

ethz.ch/en/news-and-...
“Treatment with bacteriophages can combat antibiotic-resistant infections, but Swiss patients lack access”
It is not only antibiotics but also certain viruses – known as bacteriophages – that can kill off pathogenic bacteria. However, Switzerland lacks the legal framework for the use of these viruses in th...
ethz.ch
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Reposted by Rodrigo Sánchez Martínez
gecko1990.bsky.social
Rafael Laso Pérez @gecko1990.bsky.social · 15d
Excited to highlight our News & Views on the article by Torres et al. from @delafuentelab.bsky.social team 🚀 Archaea could help to discover new antibiotics!

Read it here:
www.nature.com/articles/s41...
Deep-mining the archaeal proteome for antibiotics - Nature Microbiology
A deep-learning algorithm unravels a collection of archaeasins, peptides from the archaeal proteome with potential antimicrobial activity and implications for the development of next-generation antibiotics
www.nature.com
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Reposted by Rodrigo Sánchez Martínez
jeremyjbarr.bsky.social
Jeremy Barr @jeremyjbarr.bsky.social · 15d
Excited to annouce the latest research published by our lab, which is led by Dinesh Subedi and is out today in Nature Microbiology.

www.nature.com/articles/s41...
Rational design of a hospital-specific phage cocktail to treat Enterobacter cloacae complex infections - Nature Microbiology
The Entelli-02 phage product containing five phages has frontline potential to address infections caused by the multidrug-resistant Enterobacter cloacae complex.
www.nature.com
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Reposted by Rodrigo Sánchez Martínez
natmicrobiol.nature.com
Nature Microbiology @natmicrobiol.nature.com · 16d
Deep-mining the archaeal proteome for antibiotics

News & Views by Rafael Laso-Pérez

@gecko1990.bsky.social @delafuentelab.bsky.social

Read it here: rdcu.be/eHNwa
Deep-mining the archaeal proteome for antibiotics
Nature Microbiology - A deep-learning algorithm unravels a collection of archaeasins, peptides from the archaeal proteome with potential antimicrobial activity and implications for the development...
rdcu.be
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Reposted by Rodrigo Sánchez Martínez
ebustos-caparros.bsky.social
Esteban Bustos-Caparros @ebustos-caparros.bsky.social · 21d
Excellent work done by Borja, Miguel, and Kostas!

Differences in metagenome coverage may confound abundance-based and diversity conclusions and how to deal with them

academic.oup.com/ismecommun/a...
Differences in metagenome coverage may confound abundance-based and diversity conclusions and how to deal with them
Abstract. The importance of rarefying ecological or amplicon sequencing data to a standardized level of diversity coverage for reliable diversity compariso
academic.oup.com
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Reposted by Rodrigo Sánchez Martínez
pepa-anton.bsky.social
pepa-anton.bsky.social @pepa-anton.bsky.social · 27d
A new work on how context matters... from the PhD Thesis of Rodrigo the Great
rodrisanchez95.bsky.social
Rodrigo Sánchez Martínez @rodrisanchez95.bsky.social · 28d
🦠➡️🧬 Community context matters!
In the second part of my PhD, we show how microbial complexity drives phage–bacteria ecology & evolution.
Check out the preprint 👇🏼
biorxiv-microbiol.bsky.social
bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 28d
Biological context modulates virus-host dynamics and diversification https://www.biorxiv.org/content/10.1101/2025.09.10.675297v1
1 3
Reposted by Rodrigo Sánchez Martínez
asundelosriosbsky.bsky.social
Asunción de los Rios @asundelosriosbsky.bsky.social · 28d
Happy to share our upcoming paper on pioneer microbial communities, including viruses, establishing after glacier retreat, result of a great collaboration @ua.es @mncn-csic.bsky.social @univgirona.bsky.social @pepa-anton.bsky.social @estherrubioport.bsky.social academic.oup.com/ismecommun/a...
Short-term virus-host interactions and functional dynamics in recently deglaciated Antarctic tundra soils
Abstract. Long-term chronosequence studies have shown that, as glaciers retreat, newly exposed soils become colonized through primary succession. To determ
academic.oup.com
5 3
rodrisanchez95.bsky.social
Rodrigo Sánchez Martínez @rodrisanchez95.bsky.social · 28d
#microsky #phage #phagesky
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rodrisanchez95.bsky.social
Rodrigo Sánchez Martínez @rodrisanchez95.bsky.social · 28d
🦠➡️🧬 Community context matters!
In the second part of my PhD, we show how microbial complexity drives phage–bacteria ecology & evolution.
Check out the preprint 👇🏼
biorxiv-microbiol.bsky.social
bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 28d
Biological context modulates virus-host dynamics and diversification https://www.biorxiv.org/content/10.1101/2025.09.10.675297v1
1 4 8
Reposted by Rodrigo Sánchez Martínez
jorg-vogel-lab.bsky.social
Jörg Vogel @jorg-vogel-lab.bsky.social · 28d
Looking for a new approach to studying or eliminating phages? Check out our study introducing anti-phage ASOs (antisense oligos) out in @Nature today. nature.com/articles/s4158…
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rodrisanchez95.bsky.social
Rodrigo Sánchez Martínez @rodrisanchez95.bsky.social · 28d
Grande ese tío! Enhorabuena 👏🏼👏🏼
1
Reposted by Rodrigo Sánchez Martínez
delafuentelab.bsky.social
César de la Fuente @delafuentelab.bsky.social · Aug 12
(1/5)For over a century, the hunt for new antibiotics has focused almost exclusively on bacteria and fungi. Today, that paradigm shifts. By coupling state-of-the-art AI with the vast, largely uncharted diversity of Archaea, we open a new frontier for molecular discovery.
Deep learning reveals antibiotics in the archaeal proteome - Nature Microbiology
Use of artificial intelligence to mine proteomes of archaea led to the discovery of archaeasins, antimicrobials that kill drug-resistant bacteria in laboratory and animal models, offering a promising ...
www.nature.com
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rodrisanchez95.bsky.social
Rodrigo Sánchez Martínez @rodrisanchez95.bsky.social · Aug 4
Check out the new paper of my former lab about novel haloviruses infecting Haloquadratum walsbyi, the "square queen archaeon" of hypersaline systems 👑🟪
academic.oup.com/ismej/advanc...
Novel viruses of Haloquadratum walsbyi expand the known archaeal virosphere of hypersaline environments
Abstract. Solar salterns represent unique systems with low diversity microbial communities that serve as an excellent model for studying the evolution and
academic.oup.com
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Reposted by Rodrigo Sánchez Martínez
ghammeranne.bsky.social
Anne Grießhammer @ghammeranne.bsky.social · Jul 17
Seeing this published is even better than eating sweets! I am so happy and proud of whole @lisamaierlab.bsky.social, especially Lisa and @jdlcz.bsky.social who walked the funny/exciting/rocky road with me until the very end. Check it out!
#science #microbiome #health

www.nature.com/articles/s41...
Non-antibiotics disrupt colonization resistance against enteropathogens - Nature
Non-antibiotic drugs from a wide range of therapeutic classes can alter the ability of gut commensals to resist invasion by enteropathogens, a previously underappreciated side effect of such drugs.
www.nature.com
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Reposted by Rodrigo Sánchez Martínez
dbaquero.bsky.social
Diana Baquero @dbaquero.bsky.social · Jun 3
Kicking off my account with great news🎉: our latest paper on extracellular vesicles from human gut archaea is out in @natcomms.nature.com with
@mkrupovic.bsky.social and @sgribaldo.bsky.social!
Published in parallel with the work of our colleagues from the Moissl-Eichinger Lab @chmoei.bsky.social🧵
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Reposted by Rodrigo Sánchez Martínez
colinthb.bsky.social
Colin Buttimer @colinthb.bsky.social · May 23
Well done to Cortés Martin et al
#phage #gut #Bacteroides #CrAss
link: www.tandfonline.com/doi/full/10....
@uccresearch.bsky.social
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rodrisanchez95.bsky.social
Rodrigo Sánchez Martínez @rodrisanchez95.bsky.social · May 26
Looking for a postdoc position in microbial aquatic ecology? Apply!!!
cristian-vi-al.bsky.social
Cristian Villena Alemany @cristian-vi-al.bsky.social · May 26
🧪 We are excited to announce a Postdoc researcher position in microbial ecology for our newly funded international project between Czechia, Germany and Poland.
For more info, contact me ([email protected]) and check the link to apply for an exciting scientific journey 🧪
mbu.cas.cz/kariera/voln...
Postdoc Opportunity in Aquatic Microbial Ecology - Mikrobiologický ústav AV ČR, v. v. i.
We are looking for a motivated Postdoctoral Researcher to join our international research team of Anoxygenic Phototrophs at ALGATECH, Třeboň, Czech Academy of
mbu.cas.cz
1
Reposted by Rodrigo Sánchez Martínez
vivekmutalik.bsky.social
Vivek Mutalik @vivekmutalik.bsky.social · May 16
#phage #phagesky #microbiomesky
biorxivpreprint.bsky.social
bioRxivpreprint @biorxivpreprint.bsky.social · May 16
Emergent higher-order interactions enable coexistence in phage-bacteria community dynamics https://www.biorxiv.org/content/10.1101/2025.05.15.651590v1
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Reposted by Rodrigo Sánchez Martínez
markowenmartin.bsky.social
Mark O. Martin @markowenmartin.bsky.social · May 16
It’s Thursday! Episode #91 of #MattersMicrobial is up. Dr. Emily Davenport of Penn State joins the #QualityQuorum to discuss how host genetics impacts the microbiome. Please spread the #GoodMicrobialWord! @microbe.tv @asmicrobiology @univpugetsound

youtu.be/5c7lxC1mHxk?...
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rodrisanchez95.bsky.social
Rodrigo Sánchez Martínez @rodrisanchez95.bsky.social · May 12
Officially published! 🧬🦠
What if more phages didn't mean more death? We show that even strictly lytic phages can stabilize host populations via persistent, episomal infections (often referred to as pseudolysogeny). It's time to move beyond the lysis/lysogeny binary. #phagesky #microsky
rodrisanchez95.bsky.social
Rodrigo Sánchez Martínez @rodrisanchez95.bsky.social · Apr 11
Thrilled to share the first part of my PhD, published today in The ISME Journal! A wonderful collaboration with Akash Arani (co-first author), @joshuasweitz.bsky.social , and @mkrupovic.bsky.social . Huge thanks to my mentors Fer and Pepa for their constant support. Let’s keep going! #phage
Episomal virus maintenance enables bacterial population recovery from infection and promotes virus-bacterial coexistence
Abstract. Viruses are ubiquitous in aquatic environments with total densities of virus-like particles often exceeding 107/ml in surface marine oligotrophic
academic.oup.com
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Reposted by Rodrigo Sánchez Martínez
jaescudero.bsky.social
Jose A Escudero @jaescudero.bsky.social · May 8
🧪
Finally out after peer review, our work showing that "Mobile #Integrons carry Phage Defense Systems" is now published in Science 🎉

Short 🧵
www.science.org/doi/10.1126/...
Mobile integrons encode phage defense systems
Integrons are bacterial genetic elements that capture, stockpile, and modulate the expression of genes encoded in integron cassettes. Mobile integrons (MIs) are borne on plasmids, acting as a vehicle ...
www.science.org
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Reposted by Rodrigo Sánchez Martínez
trevor-lithgow.bsky.social
Trevor Lithgow @trevor-lithgow.bsky.social · May 1
"That telomere phages are so prevalent means that they are a selective force, one that we know little about. We now want to understand how the telomere-toxin is secreted and also understand how this ‘telocin’ wheedles its way into unsuspecting bacterial neighbors”

www.science.org/doi/10.1126/...
Telomere bacteriophages are widespread and equip their bacterial hosts with potent interbacterial weapons
Klebsiella host strains infected with telomere phages can grow to be the dominant lineage in mixed populations.
www.science.org
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Reposted by Rodrigo Sánchez Martínez
erictopol.bsky.social
Eric Topol @erictopol.bsky.social · Apr 30
To restore the gut microbiome after antibiotics, the right diet (rich in carbohydrates, low in fat) was a better approach than fecal microbial transplants (in the experimental model)
www.nature.com/articles/s41...
www.nature.com/articles/d41...
Diet outperforms microbial transplant to drive microbiome recovery in mice - Nature
Experiments in mouse models show that proper recovery of the intestinal microbiota following depletion, with or without faecal microbiota transplant therapy, is dependent on syntrophic interactions th...
www.nature.com
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Reposted by Rodrigo Sánchez Martínez
tclavel.bsky.social
Thomas Clavel @tclavel.bsky.social · Apr 29
Here we share thoughts on next-gen cultivation: rdcu.be/ejPSb. Hope it helps 😄 Was fun to write with great colleagues @lisamaierlab.bsky.social @jselkrig.bsky.social @baerboletta.bsky.social @typaslab.bsky.social @mmmicrobiomelab.bsky.social @leibniz-dsmz.bsky.social @westermannlab.bsky.social
Enabling next-generation anaerobic cultivation through biotechnology to advance functional microbiome research
Nature Biotechnology - Overcoming key hurdles for the development of next-generation anaerobic cultivation methods could have major impacts on microbial community research and applications.
rdcu.be
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