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Ryusuke Niwa @ryuniwa.bsky.social · 1d

Congratulations!

Reposted by Ryusuke Niwa

Greg Jefferis @jefferis.bsky.social · 3d

Exciting news for #drosophila #connectomics and #neuroscience enthusiasts: the Drosophila male central nervous system connectome is now live for exploration. Find out more at the landing page hosted by our Janelia FlyEM collaborators www.janelia.org/project-team....

Male CNS Connectome

A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system —a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the ...

www.janelia.org

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Ryusuke Niwa @ryuniwa.bsky.social · 10d

Discovering genes essential for stress-induced death in insects | EurekAlert! www.eurekalert.org/news-release...

Discovering genes essential for stress-induced death in insects

Researchers at University of Tsukuba identified genes and signaling pathways that trigger the death of individual insects under stress. When stress levels exceed a certain threshold, these pathways ar...

www.eurekalert.org

Ryusuke Niwa @ryuniwa.bsky.social · 21d

Discovering Genes Essential for Stress-Induced Death in Insects | Research News - University of Tsukuba www.tsukuba.ac.jp/en/research-...

Discovering Genes Essential for Stress-Induced Death in Insects | Research News - University of Tsukuba

Image by Oren Ravid/ShutterstockResearchers at University of Tsukuba identified genes and signaling pathways that trigge

www.tsukuba.ac.jp

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Ryusuke Niwa @ryuniwa.bsky.social · 23d

Our new preprint:
NudC moonlights in ribosome biogenesis and homeostasis in Drosophila melanogaster polyploid cells www.biorxiv.org/content/10.1...

NudC moonlights in ribosome biogenesis and homeostasis in Drosophila melanogaster polyploid cells

Ribosomes, the cellular machinery responsible for protein synthesis, are fundamental across all kingdoms of life. Disruption in ribosome biogenesis (RiBi) can cause severe ribosomopathies, underscorin...

www.biorxiv.org

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Ryusuke Niwa @ryuniwa.bsky.social · 29d

A new paper from our group:
Stress-induced organismal death is genetically regulated by the mTOR–Zeste–Phae1 axis | PNAS
pnas.org/doi/10.1073/...

At least in Drosophila, organismal death caused by excessive stress is not possible without the involvement of a genetic pathway.

Stress-induced organismal death is genetically regulated by the mTOR–Zeste–Phae1 axis | PNAS

All organisms are exposed to various stressors, which can sometimes lead to organismal death, depending on their intensity. While stress-induced or...

pnas.org

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Ryusuke Niwa @ryuniwa.bsky.social · Jul 9

A new preprint from our lab.

bioRxiv Cell Biology @biorxiv-cellbio.bsky.social · Jul 9

Xrp1 drives damage-induced cellular plasticity of enteroendocrine cells in the adult Drosophila midgut https://www.biorxiv.org/content/10.1101/2025.07.05.662934v1

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Ryusuke Niwa @ryuniwa.bsky.social · Apr 18

I really thank Prof. Frank Slack, my postdoc mentor, for giving me this opportunity, even though I'm not presenting anything about RNA or RNA medicine...!

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Ryusuke Niwa @ryuniwa.bsky.social · Apr 18

I will give a talk at BIDMC/Harvard, Boston, on May 9 (Fri).

Title: How is calcium ion homeostasis regulated in “boneless” invertebrates? Lessons from the fruit fly Drosophila melanogaster

us02web.zoom.us/webinar/regi...

Welcome! You are invited to join a webinar: HIRM Seminar - Ryusuke Niwa . After registering, you will receive a confirmation email about joining the webinar.

"How is calcium ion homeostasis regulated in “boneless” invertebrates? Lessons from the fruit fly Drosophila melanogaster" Speaker: Ryusuke Niwa, PhD, Associate Professor, Life Science Center for Sur...

us02web.zoom.us

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Ryusuke Niwa @ryuniwa.bsky.social · Apr 10

I will be there as an invited speaker.

The Cold Spring Harbor Laboratory Meeting "Mechanisms of Metabolic Signaling"
meetings.cshl.edu/meetings.asp...

Mechanisms of Metabolic Signaling

Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.

meetings.cshl.edu

Ryusuke Niwa @ryuniwa.bsky.social · Apr 8

Our lab group photo with cherry blossoms in April 2025.

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Reposted by Ryusuke Niwa

Bardin Lab @bardinlab.bsky.social · Mar 23

Amazing talks on the fly gut at #Dros2025 !
Fantastic how the field has grown!
Great Stem Cell and Regen session with:
#NewPI Imilce Rodriguez-Fernandez formerly Jasper lab; Yuichiro Nakajima; Jessica Sawyer- Fox lab; Anthony Galenza - O'Brien lab; Qingyin Qian of the @ryuniwa.bsky.social lab
👏👏👏

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Reposted by Ryusuke Niwa

Shinichi Nakagawa @smoltblue.bsky.social · Feb 6

I hadn’t anticipated that a ‘novel’ gene could be identified using such a straightforward approach. Remarkable dedication and devotion.

Ryusuke Niwa @ryuniwa.bsky.social · Jan 29

I am thrilled that our paper, which is packed with our 10 years of data on the venom proteins of the parasitoid wasp Asobara japonica, has just been published!

Parasitoid wasp venoms degrade Drosophila imaginal discs for successful parasitism | Science Advances www.science.org/doi/10.1126/...

Parasitoid wasp venoms degrade Drosophila imaginal discs for successful parasitism

Two parasitoid wasp venom proteins induce imaginal disc degradation of its host fly Drosophila larva, ensuring parasitism success.

www.science.org

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Ryusuke Niwa @ryuniwa.bsky.social · Feb 12

Identifying venom genes of parasitoid wasps: | EurekAlert! www.eurekalert.org/news-release...

Identifying venom genes of parasitoid wasps: Successful parasitism without immediate host death

Researchers at University of Tsukuba have identified venom genes from the endoparasitoid wasp Asobara japonica, which uses the fruit fly Drosophila melanogaster as its host. The protein...

www.eurekalert.org

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Reposted by Ryusuke Niwa

Wanhe Li @xseedling.bsky.social · Feb 6

Dear All, I believe that this thread will become one of my most important contributions to the fly field (I hope I will make other contributions)! Here, I introduce the Soy Milk Machine Fly Food Method, a.k.a., DeepCook!#Drosophila#NewPI

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Reposted by Ryusuke Niwa

Alex Gould Lab @alexgouldlab.bsky.social · Feb 4

Our latest... Congrats to Seb Sorge, Victor Girard & coauthors for devising HolFast, a chemically defined (holidic) diet for #Drosophila development that performs almost as well as a yeast diet. If you study developmental #nutrition or #metabolism please try it out... www.cell.com/developmenta...

HolFast is a new chemically defined (holidic) diet for Drosophila development that performs almost as well as a yeast diet.

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Reposted by Ryusuke Niwa

Arata Wakimoto @arataw.bsky.social · Jan 30

Its a super interesting paper about parasitoid wasps from my previous affiliation. I am feeling happy its finally out as I've seen this story alongside with my time in undergrad - gradschool life

www.science.org/doi/10.1126/...

Parasitoid wasp venoms degrade Drosophila imaginal discs for successful parasitism

Two parasitoid wasp venom proteins induce imaginal disc degradation of its host fly Drosophila larva, ensuring parasitism success.

www.science.org

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Ryusuke Niwa @ryuniwa.bsky.social · Jan 30

Thank you!

Ryusuke Niwa @ryuniwa.bsky.social · Jan 30

Thank you!

Ryusuke Niwa @ryuniwa.bsky.social · Jan 29

I am thrilled that our paper, which is packed with our 10 years of data on the venom proteins of the parasitoid wasp Asobara japonica, has just been published!

Parasitoid wasp venoms degrade Drosophila imaginal discs for successful parasitism | Science Advances www.science.org/doi/10.1126/...

Parasitoid wasp venoms degrade Drosophila imaginal discs for successful parasitism

Two parasitoid wasp venom proteins induce imaginal disc degradation of its host fly Drosophila larva, ensuring parasitism success.

www.science.org

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Ryusuke Niwa @ryuniwa.bsky.social · Jan 12

<Seminar announcement>
Jan 16 (Thu) 2025, 13:15 – 14:30 @ The seminar room, Bldg. A of TARA, Univ. Tsukuba

"Arms race between infectious retrotransposons and the piRNA pathway in animals (感染性レトロトランスポゾンとpiRNA経路の進化的関連性について)"
by Dr. Rippei Hayashi (AIU)（林立平博士）

See the poster below.

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Ryusuke Niwa @ryuniwa.bsky.social · Jan 10

Thanks!!!

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Ryusuke Niwa @ryuniwa.bsky.social · Jan 10

Thanks!!!

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Ryusuke Niwa @ryuniwa.bsky.social · Jan 10

Excited to see our new gut hormone paper in @naturecomms.bsky.social in collaboration with our alumnus Dr. Yuto Yoshinari (Gunma Univ.) and others!
A high-protein diet-responsive gut hormone regulates behavioral and metabolic optimization in Drosophila melanogaster.
www.nature.com/articles/s41...

A high-protein diet-responsive gut hormone regulates behavioral and metabolic optimization in Drosophila melanogaster - Nature Communications

Organisms regulate their feeding behavior to prevent overconsumption of certain nutrients. Here, the authors identify the importance of gut hormones in suppressing protein overfeeding.

www.nature.com

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