Samarth Hegde
@samhegde.bsky.social
1.2K followers 1.6K following 100 posts
Postdoc, Merad Lab (Sinai) | PhD, DeNardo lab (WashU) | pancreatic and lung cancer | systems myeloid immunology and immunometabolism gene regulation
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Reposted by Samarth Hegde
ucs.org
🔬✨Applications are open! The Science for Public Good Fund offers up to $1500 to support community-driven science advocacy projects. From workshops to local campaigns, you can help spark change.

🔗 Apply here now: act.ucsusa.org/4nCzPhl
Two scientists work together in a lab, one holding a test tube and the other observing. Overlaid bold yellow text reads: “Science for Public Good Fund.” Below in white text: “Apply at act.ucsusa.org/SFPG26.” Smaller italic text says: “Applications for science advocacy minigrants will be accepted through January 6th.” At the bottom is the Union of Concerned Scientists logo.
Reposted by Samarth Hegde
nycures.bsky.social
Scientists—let’s use our agency!

NY-CURES is championing a landmark statewide biomedical institute for New York, built to restore and grow science for all

Working FOR a brighter future gives us hope, purpose, and momentum.

Want to be part of it? Follow us + DM—we’ve got many ways to get involved.
Reposted by Samarth Hegde
sbagen.bsky.social
It's labor that's standing up. If the university enterprises won't do it, the faculty will have to join together to do it.
cantb.bsky.social
The AAUP and other labor groups sue the administration over its plan to charge $100,000 for every new H-1B. The AAU is not party to the suit, even though though its members among the largest employers of foreign academics. We’re seeing which groups are willing to let others take the heat.
Higher ed groups sue over Trump administration’s $100K H-1B visa fee
The surprise policy rolled out last month could cause “catastrophic setbacks” to research in the U.S., the lawsuit alleges.
www.highereddive.com
samhegde.bsky.social
NYT = NYTrash and they love trolling progressives. Don’t fall for this trap.
petersterne.com
This NYT hit piece on DSA members of the Portland City Council shows how more moderate Dems will try to frustrate all attempts by socialists to govern a city.

It's key for Mamdani supporters to understand that the campaign against Mamdani and DSA won't stop even if he's elected.
What Happens When Socialists Are in Charge? Portland Offers a Glimpse.
www.nytimes.com
Reposted by Samarth Hegde
jenna-m-norton.bsky.social
Keeping your head down Does. Not. Work.

Obeying in advance Does. Not. Work.

We need to stand together against authoritarianism. That is the only way.
gregggonsalves.bsky.social
Here's the assignment folks. Write op-eds for your local papers and campus newspapers too. Just. Say. No. This is a classic authoritarian move and risks the future of higher education and science and innovation in the US. Speak out today. No time to lose. www.nytimes.com/2025/10/02/o...
Opinion | Trump’s ‘Compact’ With Universities Is Just Extortion
www.nytimes.com
samhegde.bsky.social
OMNY in NYC is a prime example of people being forced out of non-electronic (i.e. non-surveilled) options to take public transport.
thrasherxy.bsky.social
and you should NOT be forced to sign up for a private surveillance company that will take your money above the asking price, take the merchant's money above the selling price, and tell the government + the highest bidder what you bought, what you paid and where you were (when).
Reposted by Samarth Hegde
bachynski.bsky.social
“In her complaint, the scientist, Dr. Jeanne Marrazzo, who had directed the National Institute of Allergy and Infectious Diseases, objected to Trump administration actions, alleging that they had endangered research subjects, defied court orders and undermined vaccine research.”
Kennedy Fires N.I.H. Scientist Who Filed Whistle-Blower Complaint
www.nytimes.com
Reposted by Samarth Hegde
standupforscience.bsky.social
READ ⬇️ Stand Up For Science Statement on Compact Corrupting Higher Education.
10/2/2025: Stand Up For Science Statement on Compact Corrupting Higher Education. 

Washington, D.C. — Today, the administration has unveiled their proposed "compact" for higher education. This document is antithetical to the free academic inquiry that forms the foundation of American excellence in higher education. Further, while the compact is framed as a way to promote fairness in higher education, this compact runs counter to the scientific method by prioritizing federal grant funding to go to universities who have signed, rather than proposals that have been selected by experts.
We call on university leaders to unite and reject this overreach of executive power by the White House. The compact lies in the context of an ongoing and multi-pronged attack on the integrity of the American scientific ecosystem, but this also tangibly represents the President seizing control of public spaces and higher education. Each university represents a beacon of free thought, vibrant educational empowerment, and public enrichment, and we must demand President Trump stay out of dictating universities. "Trump's compact is yet another form of attack on the American institutions that provide evidence that counter's the core belief of MAGA — racism, misogyny, and regression of the human race to name a few. If universities agree to these terms, academic freedom in America will be over," says Colette Delawalla Founder and Director of Stand Up For Science. She continues "when the White House takes over what is defined as 'truth' regardless of scientific evidence, we are no longer in a free nation. Universities must understanding the seriousness of this moment and respond accordingly." Stand Up For Science will reliably sound the alarm when science and scientists are under attack, and our platform empowers scientists to speak out and organize against corruption of American science. The proposing of this document represents an extreme authoritarian escalation for American higher education. It is crucial that university leaders, congress and the public stand together to protect higher education from this attack.
samhegde.bsky.social
@oliverbogler.bsky.social is one of the best advocates for cancer research training, I was lucky to have worked with him ! highly recommend you give this a listen 🎧
Reposted by Samarth Hegde
sahelisadanand.bsky.social
📰 Please read this important news feature in @natmed.nature.com written by @marianneguenot.bsky.social

It is impossible to reconcile this administration's alleged commitment to "Gold Standard Science" with their harmful actions against important biomedical research

www.nature.com/articles/s41...
The damage done - Nature Medicine
When clinical trials are suddenly halted by US funding cuts, there are repercussions for investigators and patients, and they do not stop at borders.
www.nature.com
Reposted by Samarth Hegde
bdlimm.bsky.social
@hamiltonnolan.bsky.social rightly encourages us to think about how unions' pension funds be used to help wage class war for the many.

In these times, one powerful use would be to motivate states to issue Blue Bonds to counter Trump's austerity—and then buy them.

moneyontheleft.org/2025/05/09/b...
Reposted by Samarth Hegde
donmoyn.bsky.social
One reason to support @aaup.org in this case is that they are not Harvard the institution, even as they are defending Harvard faculty and student rights. AAUP will not stop if the administration and Harvard leadership come to an agreement that still undercuts those rights.
aaup.org
AAUP @aaup.org · 8d
BREAKING: WE WON!!!
💥 💥 💥

Federal Judge William G. Young ruled today in our lawsuit against the Trump administration that the policy of arresting, detaining, & deporting noncitizen students & faculty members for their pro-Palestinian advocacy violates the 1st Amendment.

Full ruling here:
Findings of Fact & Conclusions of Law – #261 in American Association of University Professors v. Rubio (D. Mass., 1:25-cv-10685) – CourtListener.com
Judge William G. Young: ORDER entered. FINDINGS OF FACT AND RULINGS OF LAW, PURSUANT TO FED. R. CIV. P. 52(A)(Sonnenberg, Elizabeth) (Additional attachment(s) added on 9/30/2025: # 1 Main Document) (J...
www.courtlistener.com
samhegde.bsky.social
Captures how many of us doing groundwork around the NY mayoral election feel!
Sidenote: support local news like @thecity.nyc or @hellgatenyc.com, not enablers like the Times or WP during these times..
Reposted by Samarth Hegde
azfaust.bsky.social
In 2024, there were about 17,616 new projects awarded by the NIH. In 2025, this number was 11,190 (my number includes things like supplements). That is an ~37% cut in funding of new projects by the NIH.
Reposted by Samarth Hegde
Reposted by Samarth Hegde
needhibhalla.bsky.social
I often emphasize that there are rarely "silver bullets" that magically solve problems but vaccines are one of the closest things we have and it's mind-boggling and enraging to watch this "debate" unfold during my lifetime
ottoenglish.bsky.social
The polio immunisation program started in the USA in 1955.

Look what happened next.
samhegde.bsky.social
It was a pleasure to present at @leukocytebiology.bsky.social Building bridges seminar #BBinLB ! Excellent discussions and a great initiative to foster the showcasing of next generation science. Thank you Sofia !
Reposted by Samarth Hegde
sdeoliveira.bsky.social
🧪📣Happening in 35min! #BBinLB

There is still time to register and attend webinar from our next speaker Dr. Hegde @samhegde.bsky.social , from the Icahn School of Medicine who will present "Back to the Roots: Myeloid progenitor dysregulation fuels immunosuppressive macrophages in cancer"
Building Bridges in Leukocyte Biology Webinar Series
www.leukocytebiology.org
Reposted by Samarth Hegde
mads100tist.bsky.social
I am QT dunking but I think this is a case where it is warranted:
Science is political and "not wanting to see politics" as a scientist is a political choice. You may decide it's what works for you, but you need to decide how that fits with the fact your (diverse) colleagues still exist 🧪
mkeyoung.bsky.social
How to avoid politics on Bluesky 🦋 [THREAD]
When scientists left X, many hoped for a quieter space. But politics will take over your feeds unless you actively do something about it. This guide will help you if you just want to follow your scientific interest!
mikeyoungacademy.dk/researchers-...
Researchers are (also) stoking politics on Bluesky. Here is how to avoid it
When researchers migrated from X to Bluesky, the hope was for a quieter space. They wanted less outrage, and more science. But reality is biting back. So here are a few tips to avoid the politics anyw...
mikeyoungacademy.dk
samhegde.bsky.social
15/15: Our field is only beginning to understand the molecular mechanisms by which epigenetic remodeling occurs in tumor-educated monocytic and neutrophilic lineages, and how we can target these to alter fate or reduce accumulation in tumors.

I will continue to work on these Qs (stay tuned)! 🦴
samhegde.bsky.social
14/15: Our important discoveries would not happen without the solid support of the NIH, and @NCI_CTB F99/K00 + K99/R00. As we navigate uncharted territories in US science funding, it is *ever-important* to remind everyone how crucial these support systems are, and what we stand to lose. 📈
samhegde.bsky.social
13/15: In addition to the Merad & Brown labs, as well as expertise from others including the Ma, Tsankov, Buenrostro, Josefowicz labs, I would like to express gratitude towards the patients, their families, the surgeons, and clinic-facing teams for sharing tissue that make such studies possible. 🙏
samhegde.bsky.social
12/15: Our work also aligns with phenomenal work showing how integrated stress response (impinging on ER and mitochondrial proteostasis) can drive immunosuppressive myeloid cell behavior at the tumor site (PMID: 32294407).
samhegde.bsky.social
11/15: Priming of stress-responsive pathways (such as NRF2) is potentially a conserved mechanism of immunoregulation and survival across monocytic and neutrophil states in cancer inflammation (PMID: 38207030, 37793345). A lot more to explore in this area!