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Reposted by Samuel A. Myers' lab

Tom Lau @tomlau.bsky.social · 1d

Job alert! Looking for a mass spectrometry expert to come join our team. Please share and let me know if you have any personal recommendations. #teammassspec www.linkedin.com/jobs/view/43...

Vertex Pharmaceuticals hiring Mass Spectrometry Sr. Research Scientist in Boston, MA | LinkedIn

Posted 12:01:53 AM. Job DescriptionGeneral Summary:We are seeking a Mass Spectrometrist to join the Chemical Biology…See this and similar jobs on LinkedIn.

www.linkedin.com

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Samuel A. Myers' lab @samyers-lab.bsky.social · 2d

Not the biorender one ugh

Reposted by Samuel A. Myers' lab

Ruth Huttenhain @rhuttenhain.bsky.social · 6d

My lab @stanfordmedicine.bsky.social is recruiting! We are looking for a postdoc at the interface of quantitative proteomics and G protein-coupled receptor (GPCR) biology:
postdocs.stanford.edu/prospective/...
#TeamMassSpec #Proteomics #GPCR #Postdoc

Open Postdoctoral position, faculty mentor Ruth Huttenhain | Office of Postdoctoral Affairs

postdocs.stanford.edu

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Samuel A. Myers' lab @samyers-lab.bsky.social · 8d

Bout time

Reposted by Samuel A. Myers' lab

John Ray @jraylab.bsky.social · 20d

Excited to finally present the lab's latest work in defining candidate causal genetic variants that drive autoimmune diseases and their effects on primary human T cell expression and function! www.nature.com/articles/s41...

Genetic and epigenetic screens in primary human T cells link candidate causal autoimmune variants to T cell networks - Nature Genetics

Massively parallel reporter assay in primary human CD4+ T cells and bulk and single-cell CRISPR-interference screens identify candidate causal variants linked to autoimmune disease risk that modulate ...

www.nature.com

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Samuel A. Myers' lab @samyers-lab.bsky.social · 23d

Why 5meC and not 5mC?

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Reposted by Samuel A. Myers' lab

Science Magazine @science.org · 24d

Researchers in a recent #ScienceReview examine the influence that biological sex exerts on the immune system and immune-related diseases.

Learn more: https://scim.ag/4ln58Le

Sex differences in tissue-specific immunity and immunology

Biological sex exerts a substantial influence on the immune system and immune-related diseases. Males are more susceptible to the acute effects of viral disease and certain cancers, whereas females ex...

scim.ag

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Samuel A. Myers' lab @samyers-lab.bsky.social · 29d

So cool.

Cell Press @cellpress.bsky.social · 29d

Scientists modified a glue gun to #3Dprint bone grafts directly onto breaks during surgery. The device has so far been tested in rabbits, but has potential for future use in humans. spkl.io/63327AuO5W

@cp-device.bsky.social
#SKKU Jung Seung Lee & colleagues

Jeon et al. present a portable in situ 3Dprinting device for the fabrication of bone implants into defects with irregular geometries. Depending on the components or additives in the extrudable composites, biofunctionality and physical properties can be tailored, supporting bone regeneration. The printing of artificial bone constructs in situ with controllable shapes and functionalities can benefit patientspecific bone-defect treatments

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Reposted by Samuel A. Myers' lab

@KingOfPathogens @kingofpathogens.bsky.social · Sep 1

In @elife.bsky.social: IL-27 limits HSPC differentiation during infection and protects from stem cell exhaustion doi.org/10.7554/eLif...

IL-27 limits HSPC differentiation during infection and protects from stem cell exhaustion

doi.org

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Reposted by Samuel A. Myers' lab

Dr. David Miller 🏳️‍🌈 @davidimiller.bsky.social · Sep 1

🧪 And House appropriators say: no cuts to NIH budget!

House subcommittee version just came out (link below). Holds NIH flat at $48 billion.

To be clear: this is far from over. But a good sign that science still matters across both sides of aisle.

YOUR VOICE MATTERS!!

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Samuel A. Myers' lab @samyers-lab.bsky.social · Aug 28

We make cell engineering look easy....

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Samuel A. Myers' lab @samyers-lab.bsky.social · Aug 27

Morgan gave such a fascinating talk at a @cshlaboratory.bsky.social meeting last year we had to invite him for an encore. Please join us @lji.org! via @mskcancercenter.bsky.social

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Reposted by Samuel A. Myers' lab

Rita Strack @ritastrack.bsky.social · Aug 23

A generation of scholarship, put on hold or lost. share.google/5Pw7Akh79qec...

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Reposted by Samuel A. Myers' lab

Nature Chemical Biology @natchembio.nature.com · Aug 21

A new paper reports direct ubiquitination of a small molecule BRD1732 in cells. BR31732 ubiquitination is E3 ligase-dependent and leads to inhibition of proteasomal degradation.

www.nature.com/articles/s41...

Highly specific intracellular ubiquitination of a small molecule - Nature Chemical Biology

Li et al. discovered that the cytotoxic synthetic small molecule BRD1732 is directly ubiquitinated in cells. Ubiquitination of BRD1732 is E3 ligase dependent and leads to inhibition of proteasomal deg...

www.nature.com

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Samuel A. Myers' lab @samyers-lab.bsky.social · Aug 20

Celebrating Al Burlingame's 41 years of the @asbmb.bsky.social Molecular and Cellular Proteomics meeting which he started before "proteomics" was a term. Congrats Al!

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Reposted by Samuel A. Myers' lab

Sweet Papers 🤖 @sweetpapers.proteaglyco.com · Aug 17

Evidence for Functional Regulation of the KLHL3/WNK Pathway by O-GlcNAcylation
#glycotime #Glycobiology

Evidence for Functional Regulation of the KLHL3/WNK Pathway by O-GlcNAcylation

Abstract. The 42-member Kelch-like (KLHL) protein family are adaptors for ubiquitin E3 ligase complexes, governing the stability of a wide range of substra

academic.oup.com

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Reposted by Samuel A. Myers' lab

Nature Cell Biology @natcellbio.nature.com · Aug 14

🍹Zhang, Ma et al. report that ROS-activated O-GlcNAc transferase promotes FOXK2 O-GlcNAcylation and nuclear translocation to upregulate SLC7A11 expression, thereby modulating #ferroptosis sensitivity, #tumor development and chemoradiotherapy efficacy.
👉https://rdcu.be/eAN1I
bit.ly/3JasCWN

A ROS-mediated oxidation-O-GlcNAcylation cascade governs ferroptosis - Nature Cell Biology

Zhang, Ma et al. report that ROS-activated O-GlcNAc transferase promotes FOXK2 O-GlcNAcylation and nuclear translocation to upregulate SLC7A11 expression, thereby modulating ferroptosis sensitivity, t...

bit.ly

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Samuel A. Myers' lab @samyers-lab.bsky.social · Aug 13

Sickkkkkkk

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Reposted by Samuel A. Myers' lab

Fleur Ferguson @fleurmferguson.bsky.social · Aug 11

Excited to share our latest work developing molecular glue degraders of ZBTB11, now out in @natchembio.nature.com
www.nature.com/articles/s41...

ZBTB11 depletion targets metabolic vulnerabilities in KRAS inhibitor-resistant PDAC - Nature Chemical Biology

Depletion of a transcriptional factor ZBTB11 using molecular glue degraders can overcome oxidative-phosphorylation-mediated KRAS inhibitor resistance in pancreatic ductal adenocarcinoma with low acute...

www.nature.com

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Samuel A. Myers' lab @samyers-lab.bsky.social · Aug 9

How do you know the smell of opium?

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Reposted by Samuel A. Myers' lab

Hattie Chung @hattaca.bsky.social · Aug 8

Our lab at Yale @yalemedicine.bsky.social seeks #postdocs with in vivo expertise to pioneer research at the intersection of tissue remodeling & aging. Work with us to uncover immunological & vascular drivers of ovarian aging, applying single-cell, spatial omics, and ML! jobrxiv.org/job/yale-uni...

Postdoctoral Fellow, Hattie Chung Lab (Yale School of Medicine)

Post a job in 3min, or find thousands of job offers like this one at jobRxiv!

jobrxiv.org

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Samuel A. Myers' lab @samyers-lab.bsky.social · Aug 5

What... on earth...am I looking at?!?

Pawel Burkhardt @pawelburkhardt.bsky.social · Aug 4

Marine biodiversity: Gone with the wind? Our dispatch out now in @currentbiology.bsky.social

New research shows that wind and currents act as invisible barriers, reshaping our view of ocean connectivity. 🌊🪼

authors.elsevier.com/a/1lYLj3QW8S...
@iramaegele.bsky.social @msarscentre.bsky.social

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Samuel A. Myers' lab @samyers-lab.bsky.social · Jul 31

send me a postcard

Samuel A. Myers' lab @samyers-lab.bsky.social · Jul 31

you can unclench a little bit....

Carl Zimmer @carlzimmer.com · Jul 31

Senate committee endorses NIH budget increase, rebuking Trump administration’s proposed 40% cut www.statnews.com/2025/07/31/n...

Senate committee endorses NIH budget increase, rebuking Trump administration’s proposed 40% cut

Senators from both parties endorsed a $400 million increase to the budget of the National Institutes of Health on Thursday

www.statnews.com

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Reposted by Samuel A. Myers' lab

Prof. Shane Crotty @profshanecrotty.bsky.social · Jul 30

After 30+ years of HIV vaccine clinical trials, this is the first time that neutralizing antibodies against an HIV clinical isolate has been generated in vaccinated people.

* "Tier 2" neutralizing antibodies, induced consistently.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...

Vaccination with an mRNA-encoded membrane-bound HIV envelope trimer induces neutralizing antibodies in animal models

An HIV envelope trimer mRNA vaccine enables membrane-bound expression and produces a functional immunogen in preclinical mammalian models.

www.science.org

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