Séb Wielgoss
@sebwielgoss.bsky.social
11 followers 21 following 2 posts
Senior Scientist, Microbiologist
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Reposted by Séb Wielgoss
evolvedbiofilm.bsky.social
Cool PNAS paper by @jordivangestel.bsky.social and colleagues
Contributed by Carol Gross
[reviewed by @polzlab.bsky.social and @wcratcliff.bsky.social]

Bacillus subtilis in defense mode: Switch-like adaptations to protistan predation

www.pnas.org/doi/10.1073/...
Reposted by Séb Wielgoss
Reposted by Séb Wielgoss
polzlab.bsky.social
Longstanding collaboration with Scott Manalis where we have developed technology to measure single cell growth rates of bacteria in native seawater with some very surprising results.
www.biorxiv.org/content/10.1...
Reposted by Séb Wielgoss
skyjase.bsky.social
very cool work and a milestone in synthetic biology. how impressive are the new phage genomes?

with generative bioML, i'm always looking at how similar the generated sequences are to known sequences. let's take a look
samuelhking.bsky.social
Many of the most complex and useful functions in biology emerge at the scale of whole genomes.

Today, we share our preprint “Generative design of novel bacteriophages with genome language models”, where we validate the first, functional AI-generated genomes 🧵
Reposted by Séb Wielgoss
geschichte.fm
Mittwoch! Passend zur Sommerszeit: eine kleine Geschichte der Sonnenbrille. Wir sprechen nicht nur über ihre Anfänge, sondern vor allem über die Bedeutung, die sie im Laufe ihrer Geschichte erhalten hat.

https://www.geschichte.fm/archiv/gag512/
GAG512: Eine kleine Geschichte der Sonnenbrille - Geschichten aus der Geschichte
Eine Geschichte über Sonnenschutz, Identität und Rebellion
www.geschichte.fm
Reposted by Séb Wielgoss
marcrr.ecoevo.social.ap.brid.gy
@eseb Distinguished Fellow Talk Dieter Ebert 🇨🇭, has been an ESEB member since his PhD and played a key role in the society all of his career. #eseb2025
Reposted by Séb Wielgoss
dieterlukas.fediscience.org.ap.brid.gy
"Overall, the message from this survey is positive– #evolutionary #biologists are readily employable outside of #academia, generally well-prepared for those jobs, and report high levels of satisfaction in their non-academic #careers"

https://www.biorxiv.org/content/10.1101/2025.08.19.671061v1
A scientific figure from the linked paper by Betancourt et al. It shows on the left, that most (70%) evolutionary biologists who switched to a career outside of academia felt prepared. The right panel is a graph showing what training individuals would like to have received more of during their academic career, with the top points being related to management skills.
sebwielgoss.bsky.social
Need advice on which of the many virus 🦠 prediction tools to apply for your phage research🔎?

This guide equips you for your bioinformatic analyses in your
"quest to explore the genetic diversity and biology of the smallest and most abundant replicators on Earth."

⬇️

doi.org/10.1093/bib/...
Phage quest: a beginner’s guide to explore viral diversity in the prokaryotic world
Abstract. The increasing interest in finding new viruses within (meta)genomic datasets has fueled the development of computational tools for virus detectio
doi.org
Reposted by Séb Wielgoss
relenski.bsky.social
Excited to share new #program, STEPS, which can simulate #dynamics of the E. coli Long-Term Evolution Experiment (#LTEE) or other microbes in serial transfer regime.

telliamedrevisited.wordpress.com/2025/08/12/s...

STEPS developed by @devinmlake.bsky.social, Zachary Matson, Minako Izutsu, and me.
STEPS To It
Announcing a new program, called STEPS, to simulate the dynamics of evolving microbial populations.
telliamedrevisited.wordpress.com
Reposted by Séb Wielgoss