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sfb1454.bsky.social @sfb1454.bsky.social · 27d

🚀 Angelika Rambold presented her exciting research in our #SFB1454 seminar series mapping organelles dynamics during immune cell activation. Fascinating insights into cell dynamics! 🔬🧫 #CellBiology #Immunology #OrganelleDynamics

sfb1454.bsky.social @sfb1454.bsky.social · Aug 21

Great teamwork by the @wachtenlab.bsky.social tenlab.bsky.social @masslab.bsky.social in our #SFB1454! Congratulations to the whole team!

WachtenLab @wachtenlab.bsky.social · Aug 21

🚨 New in The EMBO Journal!
Loss of BBS8 disrupts ciliary Hedgehog signaling, switching adipocyte precursors into fibrogenic cells—remodeling adipose tissue before obesity begins.
🔬 #BBS #cilia @for5547.bsky.social @sfb1454.bsky.social @batenergy.bsky.social
📄 www.embopress.org/doi/full/10....

BBS8-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue | The EMBO Journal

imageimageDisruption of ciliogenesis in Bardet-Biedl syndrome (BBS) leads to obesity and disrupted adipogenesis. This study reveals that ciliary dysfunction in a mouse model of BBS induces a a cell fa...

www.embopress.org

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WachtenLab @wachtenlab.bsky.social · Jun 30

💡 Paper alert! We developed DEL-VPR, a potent blue-light photoswitch inducing gene expression in mammalian cells.
From basic research to antibody production, this tool offers precise & strong gene control. Teamwork with #Ningaloo
academic.oup.com/nar/article/...
#SyntheticBiology #Optogenetics

Potent optogenetic regulation of gene expression in mammalian cells for bioproduction and basic research

Abstract. Precise temporal and spatial control of gene expression greatly benefits the study of specific cellular circuits and activities. Compared to chem

academic.oup.com

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sfb1454.bsky.social @sfb1454.bsky.social · Jun 25

Interested in the "fifty shades of fat" - have a look at the german article in Spiegel online with contribution from our SFB @wachtenlab.bsky.social together with @batenergy.bsky.social www.spiegel.de/fitness/fitn...

(S+) Fitness: Fifty Shades of Fett – und nicht alle sind böse

Ganz wegtrainieren lässt es sich nie. Es kann gefährlich sein, aber auch sehr vorteilhaft: Fett ist fast überall in unserem Körper und kennt drei Farbtöne. Zehn Dinge, die Sie darüber bestimmt noch ni...

www.spiegel.de

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sfb1454.bsky.social @sfb1454.bsky.social · Jun 19

Exciting new story in @nature.com ‬ by the @masslab.bsky.social together with SFB1454 PIs‪ @wachtenlab.bsky.social @meissner-lab.bsky.social and others: Children born to obese mothers are at higher risk of metabolic disease—even with a healthy diet #macrophages

Mass Lab @masslab.bsky.social · Jun 18

We are SO EXCITED to share our story @nature.com:
🧵1/
Maternal obesity reprograms fetal liver macrophages, triggering adult fatty liver disease in the offspring.
This study uncovers how Kupffer cells act as intergenerational messengers in metabolic disease.
👉 Read here: rdcu.be/erD3b

Kupffer cell programming by maternal obesity triggers fatty liver disease

Nature - In a mouse model, maternal obesity during pregnancy can lead to fatty liver disease in the offspring, driven by aberrant developmental programming of Kuppfer cells.

rdcu.be

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Dr Róisín McManus @roisinmcmanus.bsky.social · Jun 2

🥼 We’re looking for a #MSc student to work in our lab as part of their MSc thesis or internship on an interdisciplinary project @dzne.science, in Germany!

🧠 If you’re interested in #neuroinflammation and innate immune signalling in #alzheimersdisease, check out our ad👇

jobs.dzne.de/en/jobs/1014...

Master student (f/m/x) in the field of Neuroimmunology 1447/2025/6

jobs.dzne.de

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Sparwasser Lab @timsparwasser.bsky.social · May 26

Special issue Immunometabolism and Beyond: from Liver to Brain!
European Journal of Immunology
Article types: reviews and research articles
Submission deadline 1 November 2025
Thanks to Nadja, Matteo and Bin for this wonderful opportunity!
#immunometabolism #EJI #CRC1292 #CRC355 #CRC156 #FZI

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sfb1454.bsky.social @sfb1454.bsky.social · May 25

Great to see research from our SFB featured at the Bardet-Biedl Syndrome Patient Days 2024! Fantastic discussions and engagement! #BBS #cilia #metaflammation

FOR5547 Primary cilia dynamics @for5547.bsky.social · May 25

Fantastic discussions and interactions at the Bardet-Biedl Syndrome Patient Days 2024 — huge thanks to Helen for organizing such a meaningful event! #cilia #BBS @wachtenlab.bsky.social

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sfb1454.bsky.social @sfb1454.bsky.social · May 23

👏 Huge congratulations to the @immunosens.bsky.social team!
Incredible news that @dfg.de will fund ImmunoSensation3 focusing on Immune Diversity.
Here’s to 7 more years of groundbreaking #immunology in #Bonn! 🧬🎉
#ImmunoSensation3 #ScienceFunding #Celebrate

Cluster of Excellence ImmunoSensation @immunosens.bsky.social · May 22

Hurray! ImmunoSensation will go on! 🥳
The @dfg.de just announced that ImmunoSensation3, focussing on Immune Diversity will be funded!
Let us #celebrate 7 more years of #immunology in #Bonn 🎉

www.immunosensation.de/news/immunos...

Excellence Strategy Funds Bonn Cluster for Immune Research

The Bonn Cluster of Excellence ImmunoSensation will be funded for a further seven years as part of the Excellence Strategy of the German federal and state…

www.immunosensation.de

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sfb1454.bsky.social @sfb1454.bsky.social · May 22

Great to see PIs from @sfb1454.bsky.social contributing to Immunometabolism & beyond – from liver to brain!
A fantastic event full of inspiring talks and discussions. We're really happy to be part of it! 🙌 Thanks a lot for having us!
#immunometabolism #DFG

Sparwasser Lab @timsparwasser.bsky.social · May 22

Immunometabolism & beyond - from liver to brain.
A great success! Tx to all the speakers and participants for fantastic talks and good discussions! #immunometabolism #DFG #Universitätsmedizin Mainz

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sfb1454.bsky.social @sfb1454.bsky.social · Apr 25

"Fantastic collaboration between our @sfb1454.bsky.social PIs @masslab.bsky.social and Marc Beyer - huge congratulations to the entire team on this achievement!"

Reposted

Cluster of Excellence ImmunoSensation @immunosens.bsky.social · Apr 25

Visit us at the Day of Immunology 2025!

This Saturday, April 26, you can see us at our tent at the Marktplatz in #Bonn and listen to the interesting talks at the Poststraße 26.

Visit our website for more information: www.immunosensation.de/events/day-o...

#dayofimmunology #science #immunology

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Cluster of Excellence ImmunoSensation @immunosens.bsky.social · Apr 16

🌍 We celebrate the international Day of Immunology!

Join us April 26 at the Marktplatz and P26 in #Bonn and check out our oversized organ models, discuss immunological topics with scientists, and perform interesting experiments.

#dayofimmunology #science #immunology #event

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sfb1454.bsky.social @sfb1454.bsky.social · Apr 3

🚀 Exciting #SciComm in action! @masslab.bsky.social explores how our diet—especially micro- & nanoplastics—impacts the immune system 🦠🛡️ #Macrophages. A fantastic addition to our #Healthybition "what the health exhibition" at Museum Koenig, Bonn! Join us in bridging science & public awareness. 🔬✨

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Cluster of Excellence ImmunoSensation @immunosens.bsky.social · Mar 27

Applications are open for the 4th International School on Advanced Immunology!

Full board accommodation is covered by ImmunoSensation, with potential travel subsidies available (please note we do not cover full travel costs).

More information can be found under: www.advanced-immunology.net

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sfb1454.bsky.social @sfb1454.bsky.social · Mar 19

New collaborative effort from our #metaflammation SFB1454 PIs headed by @masslab.bsky.social

Mass Lab @masslab.bsky.social · Mar 18

1/ 🚨 New preprint alert! 🚨
Micro- and nanoplastics (MNPs) are everywhere, but what happens when they get inside us? Our latest study reveals how chronic plastic exposure affects macrophages and metabolism in a size-dependent manner. 🧵👇 www.researchsquare.com/article/rs-6...

Size-dependent plastic exposure disrupts macrophage function and tissue-specific metabolism

Plastic pollution is an emerging yet understudied environmental risk to the immune system. Once ingested, nano- and microplastic particles (MNPs) can translocate from the gut to internal organs, with ...

www.researchsquare.com

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sfb1454.bsky.social @sfb1454.bsky.social · Mar 12

Check out this great collaboration project from our #metaflammation SFB members!

Mass Lab @masslab.bsky.social · Mar 11

We are thrilled to present our new story on #neonatal #liver #macrophages and how they crosstalk with #hepatocytes during this early stage of life
👇

bioRxivpreprint @biorxivpreprint.bsky.social · Feb 24

Kupffer cells control neonatal hepatic metabolism via Igf1 signaling https://www.biorxiv.org/content/10.1101/2025.02.19.638983v1

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sfb1454.bsky.social @sfb1454.bsky.social · Mar 10

*Job Opportunity*

Prof. Sven Burgdorf is seeking a Postdoc in Cellular Immunology and Metabolism as part of our SFB!

If you are passionate about #CellularImmunology and #Metaflammation find out more here:

www.uni-bonn.de/de/universit...

Postdoc in cellular immunology and metabolism

Full time, temporary, EG 13, Reference number: 3.3/2025/13

www.uni-bonn.de

sfb1454.bsky.social @sfb1454.bsky.social · Feb 12

*Job Opportunity*

Prof. Dominic Lemken is seeking a PhD candidate to research Consumer Behavior and Food Choices as part of our SFB!

If you are passionate about #ConsumerBehavior and #FoodEconomics find out more here:
www.uni-bonn.de/de/universit...

www.uni-bonn.de

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sfb1454.bsky.social @sfb1454.bsky.social · Feb 4

Congratulations to the whole team! Exciting new data from the #SFB1454 - a must read for those interested in #metabolism in #microglia!

Dr Róisín McManus @roisinmcmanus.bsky.social · Feb 3

I am thrilled to share our latest article that has been published in @cp-immunity.bsky.social. We describe a new role for NLRP3 outside of its #inflammasome complex, where it can regulate microglial #metabolism & key metabolites that affect the epigenetic landscape(1)
www.cell.com/immunity/ful...

NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer’s disease progression

How NLRP3 impacts Alzheimer’s disease (AD) is unclear. McManus et al. find that NLRP3 is located at mitochondria where it regulates microglial metabolism. Depletion or chronic pharmacological inhibiti...

www.cell.com

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sfb1454.bsky.social @sfb1454.bsky.social · Jan 30

Kicking off the 2nd funding period of our SFB1454 on #metaflammation ! Lots of great discussions and visiting our #healthybition at the #museumkoenig in Bonn! Go and visit the exhibition until end of October 2025!

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Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · Jan 25

Decoding cilia signaling and function by the one and only @wachtenlab.bsky.social Thanks for delivering a fantastic #FEBS national lecture at the Norwegian bioscience society winter meeting.

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sfb1454.bsky.social @sfb1454.bsky.social · Jan 22

Great conference organized by our colleagues - register if you are interested in #brownfat function and metabolism! Looking forward seeing you in Bonn!

TRR333 BATEnergy @batenergy.bsky.social · Jan 22

We would like to welcome you to our second International Conference on Brown and Beige Fat
March 31st - April 02nd 2025
Top-class speakers, cutting edge research and respected experts will come together in beautiful Bonn.
Registration is open!
www.trr333.uni-bonn.de/batenergy-sy...

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Surace Lab @suracelab.bsky.social · Jan 14

🚨 Job alert 🚨
1 PhD + 1 Technician
Our lab is looking for motivated candidates interested in understanding the impact of diets and lifestyle on tumor development, anti-tumor immunity and metastasis! Apply and join our team!
Info below 👇

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Cluster of Excellence ImmunoSensation @immunosens.bsky.social · Jan 15

🚨 Open #position! The group of Christoph Wilhelm at the University Hospital Bonn is looking for a

Postdoctoral fellow (m/f/d) – metabolic and nutritional regulation of immunity

Application deadline is February 10!

Visit our website for more information.

#job #postdoc #science #immunology

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