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Reposted by WachtenLab

The EMBO Journal @embojournal.org · Sep 1

Primary #cilia dysfunction as in Bardet-Biedl syndrome compromises normal adipogenic differentiation in favor of fibrogenic transition, predisposing to obesity
@wachtenlab.bsky.social and collaborators
www.embopress.org/doi/full/10....

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WachtenLab @wachtenlab.bsky.social · Aug 21

🚨 New in The EMBO Journal!
Loss of BBS8 disrupts ciliary Hedgehog signaling, switching adipocyte precursors into fibrogenic cells—remodeling adipose tissue before obesity begins.
🔬 #BBS #cilia @for5547.bsky.social @sfb1454.bsky.social @batenergy.bsky.social
📄 www.embopress.org/doi/full/10....

BBS8-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue | The EMBO Journal

imageimageDisruption of ciliogenesis in Bardet-Biedl syndrome (BBS) leads to obesity and disrupted adipogenesis. This study reveals that ciliary dysfunction in a mouse model of BBS induces a a cell fa...

www.embopress.org

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Reposted by WachtenLab

Ningaloo Biosystems @ningaloobio.bsky.social · Jul 21

🚨 Catching up with great news!
Our NAR paper with the @wachtenlab.bsky.social and supported by Prof. Möglich presents a powerful light-switch for gene expression in mammalian cells, with big potential for bioproduction and research.

#Optogenetics #SyntheticBiology #Bioproduction #GeneExpression

Potent optogenetic regulation of gene expression in mammalian cells for bioproduction and basic research

Abstract. Precise temporal and spatial control of gene expression greatly benefits the study of specific cellular circuits and activities. Compared to chem

academic.oup.com

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WachtenLab @wachtenlab.bsky.social · Jun 30

💡 Paper alert! We developed DEL-VPR, a potent blue-light photoswitch inducing gene expression in mammalian cells.
From basic research to antibody production, this tool offers precise & strong gene control. Teamwork with #Ningaloo
academic.oup.com/nar/article/...
#SyntheticBiology #Optogenetics

Potent optogenetic regulation of gene expression in mammalian cells for bioproduction and basic research

Abstract. Precise temporal and spatial control of gene expression greatly benefits the study of specific cellular circuits and activities. Compared to chem

academic.oup.com

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Reposted by WachtenLab

Mass Lab @masslab.bsky.social · Jun 18

We are SO EXCITED to share our story @nature.com:
🧵1/
Maternal obesity reprograms fetal liver macrophages, triggering adult fatty liver disease in the offspring.
This study uncovers how Kupffer cells act as intergenerational messengers in metabolic disease.
👉 Read here: rdcu.be/erD3b

Kupffer cell programming by maternal obesity triggers fatty liver disease

Nature - In a mouse model, maternal obesity during pregnancy can lead to fatty liver disease in the offspring, driven by aberrant developmental programming of Kuppfer cells.

rdcu.be

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WachtenLab @wachtenlab.bsky.social · Jun 7

Huge congratulations on the launch of your lab at UCSF! 🎉 Excited to see the amazing science to come on airway stem cells and multiciliated cell biology. Wishing the @choksilab all the best as you get started! 🧬💨 #NewLab #STEM

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WachtenLab @wachtenlab.bsky.social · May 27

Looking forward to an inspiring 2-day #iii institute retreat packed with great science, collaborations, and fresh ideas. Grateful to @unibonn.bsky.social for hosting us in #IMPULSE! 🙌🔬

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WachtenLab @wachtenlab.bsky.social · May 23

Huge congratulations! 🎉

Universität Bonn @unibonn.bsky.social · May 22

We are excellent! What a day - between hugs, applause and a lot of pride. Our rector? Jumping for joy. Our team? Overjoyed. Thank you to everyone who made this historic moment possible! @dependencybonn.de @immunosens.bsky.social @econtribute.bsky.social
© V. Lannert/G. Hübl/Uni Bonn

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WachtenLab @wachtenlab.bsky.social · May 23

Thrilled to be part of this amazing journey! 🙌 Hurray indeed! @dfg.de has just approved funding for ImmunoSensation3 🎉 Focused on Immune Diversity, we're set for 7 more years of cutting-edge #immunology in #Bonn! Let’s go! 💥 #ImmunoSensation #science

Cluster of Excellence ImmunoSensation @immunosens.bsky.social · May 22

Hurray! ImmunoSensation will go on! 🥳
The @dfg.de just announced that ImmunoSensation3, focussing on Immune Diversity will be funded!
Let us #celebrate 7 more years of #immunology in #Bonn 🎉

www.immunosensation.de/news/immunos...

Excellence Strategy Funds Bonn Cluster for Immune Research

The Bonn Cluster of Excellence ImmunoSensation will be funded for a further seven years as part of the Excellence Strategy of the German federal and state…

www.immunosensation.de

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WachtenLab @wachtenlab.bsky.social · May 14

Proud PI - congratulations to Seniz for being awarded the "Rising Star" award of the @for5547.bsky.social #cilia

FOR5547 Primary cilia dynamics @for5547.bsky.social · May 14

Grateful to be part of such a fantastic consortium! Huge thanks to our amazing coordinator Christina and to Silke for organizing an inspiring annual meeting in Jena. Latest new: we’ve got a new rising star on the team! #cilia

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Reposted by WachtenLab

FOR5547 Primary cilia dynamics @for5547.bsky.social · May 14

Grateful to be part of such a fantastic consortium! Huge thanks to our amazing coordinator Christina and to Silke for organizing an inspiring annual meeting in Jena. Latest new: we’ve got a new rising star on the team! #cilia

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WachtenLab @wachtenlab.bsky.social · May 4

🎉 Huge congratulations to Susan Dutcher @dutcherlab.bsky.social on her election to the National Academy of Sciences! A well-deserved recognition of her outstanding contributions to cell biology and cilia research. 👏🔬 #WomenInSTEM #Cilia

WashU Ciliopathy Research Group @wu-ciliopathygroup.bsky.social · May 2

Major congratulations to our fearless leader and team captain Susan Dutcher @dutcherlab.bsky.social for being elected to the National Academy of Sciences! 🙌

Another big win for #cilia biology!!

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WachtenLab @wachtenlab.bsky.social · Apr 15

We’ll miss you! Best of luck kicking off your own lab in Berlin — exciting times ahead!

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FOR5547 Primary cilia dynamics @for5547.bsky.social · Apr 15

Excited for an inspiring meeting in France 🇫🇷 on #cilia and #centrosomes! The German #cilia community is en route—let’s connect and share science!

Philippe Bastin's Lab @bastinlab.bsky.social · Apr 14

Dear cilia researchers, join us in the heart of the beautiful Vosges mountains to share your latest findings! This year, partnership with @for5547.bsky.social and keynote lectures by @micromotility.bsky.social and @mick-lab.bsky.social
Registration is now open www.cfc2025.conferences-pasteur.org

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Reposted by WachtenLab

Philippe Bastin's Lab @bastinlab.bsky.social · Apr 14

Dear cilia researchers, join us in the heart of the beautiful Vosges mountains to share your latest findings! This year, partnership with @for5547.bsky.social and keynote lectures by @micromotility.bsky.social and @mick-lab.bsky.social
Registration is now open www.cfc2025.conferences-pasteur.org

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WachtenLab @wachtenlab.bsky.social · Apr 2

Congratulations to Ronja from the @wachtenlab.bsky.social , who won the 1st poster prize at the international @batenergy.bsky.social meeting! 🎉🥳

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WachtenLab @wachtenlab.bsky.social · Mar 14

Congratulations Kathrin and the whole team!!!

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WachtenLab @wachtenlab.bsky.social · Mar 7

Congratulations and well deserved 🎉🥳

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Reposted by WachtenLab

Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · Mar 7

Cilia has been at the center of our discussions at the spring school of our @for5547.bsky.social cilia consortium.
In total there were 26 trainees from across Europe, few PIs and our brilliant coordinator Christina Klausen.

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Reposted by WachtenLab

David Mick @mick-lab.bsky.social · Feb 22

Interested in primary #cilia, #microtubules, #protein trafficking, molecular #signaling, #GPCRs, and #ciliopathies?

We are looking for a #postdoc and a #PhDstudent to apply advanced #biochemistry and #proteomics methods to study cilia.
Check out our website and send your application until March 10.

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WachtenLab @wachtenlab.bsky.social · Feb 16

See you soon!

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WachtenLab @wachtenlab.bsky.social · Jan 25

Thanks a lot to #FEBS and the Norwegian bioscience society for hosting me and special thanks to @nathaliejuya.bsky.social and @emreyaksi.bsky.social for your hospitality!

Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · Jan 25

Decoding cilia signaling and function by the one and only @wachtenlab.bsky.social Thanks for delivering a fantastic #FEBS national lecture at the Norwegian bioscience society winter meeting.

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WachtenLab @wachtenlab.bsky.social · Jan 23

Looking forward to #Cilia 2027 - watch out for more information!

Alessandra Boletta @bolettalab.bsky.social · Jan 23

🚧 Work in progress for cilia 2027!

🙏 thanks to this amazing group of scientists, clinicians and patient advocates for joining the Cilia 2027 organizing committee!

🌸 Spring 2027 in Milan, more to follow

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Reposted by WachtenLab

TRR333 BATEnergy @batenergy.bsky.social · Jan 22

We would like to welcome you to our second International Conference on Brown and Beige Fat
March 31st - April 02nd 2025
Top-class speakers, cutting edge research and respected experts will come together in beautiful Bonn.
Registration is open!
www.trr333.uni-bonn.de/batenergy-sy...

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WachtenLab @wachtenlab.bsky.social · Jan 18

This will open up proximity labeling to a broad cell biology community, allowing protein labeling in subcellular domains without background labeling. This is a major step forward to now do in vivo labeling using #iAPEX - congratulations to the whole team!