Lightnews — Scholar-powered news

Reposted by David Mick

Science Magazine @science.org · 12h

New findings in mice cast light on the pathways behind the growth of painful bone tumors in hereditary multiple osteochondroma and suggest that these mechanisms could be targeted to slow the disease’s progression.

Learn more in #ScienceSignaling: https://scim.ag/46VRSIp

An ectopic Hedgehog signaling axis drives directional tumor outgrowth in a mouse model of hereditary multiple osteochondromas

Redeployment of a developmental program drives the outgrowth of bone tumors in an inherited disease.

scim.ag

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Reposted by David Mick

EMBL-EBI @ebi.embl.org · 1d

We’re renewing our collaboration with Google DeepMind!

We'll keep developing the AlphaFold Database to support protein science worldwide 🎉

To mark the moment we’ve synchronised the database with UniProtKB release 2025_03.

www.ebi.ac.uk/about/news/t...

🖥️🧬 #AlphaFold
@pdbeurope.bsky.social

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David Mick @mick-lab.bsky.social · 1d

Deeply saddened to hear about the passing of Jochen. We had very few but absolutely fantastic interactions when he was still in Dresden. He will be missed dearly.

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Reposted by David Mick

HuranovaLab @huranovalab.bsky.social · 4d

Today is the #BBSGlobalDay — an opportunity to raise awareness of this rare condition and offer support to everyone living with BBS and their loved ones 🌍 🌎 🌏
www.img.cas.cz/2025/10/8758...

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David Mick @mick-lab.bsky.social · Aug 30

Can I invite myself?

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Bianca Schrul @biancaschrul.bsky.social · Aug 22

First pizza lunch after a whirlwind week moving into our brand-new research building. Exhausted, but absolutely thrilled by the incredible facilities & lab space. Can’t wait to dive back into science.
A few benches are still waiting for curious minds: PhD students and postdocs, come join us! 😉

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Reposted by David Mick

Thiago Carvalho @cyrilpedia.bsky.social · Aug 10

'This story shows that it is possible to establish a multibillion-dollar industry purely by letting scientists communicate their research, exchange information and share materials.'
www.nature.com/articles/d41...

Monoclonal antibodies revolutionized biomedical science and health care

The story of the discovery of these molecules 50 years ago shows how the free exchange of ideas can lead to life-changing treatments.

www.nature.com

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Reposted by David Mick

Itai Yanai @itaiyanai.bsky.social · Aug 9

Science doesn’t need to be pretty and go according to plan; it just needs to lead to a discovery. If doesn’t have to be done alone or together with someone else; there just needs to be a discovery. It doesn’t need to happen fast or slow; just as long as there’s a discovery, then everybody is happy.

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Kat Toropova @kattoropova.bsky.social · Jul 29

Thrilled to see our study on how kinesin-2 motors are switched on and off published in @natsmb.nature.com ⚛️

➡️ www.nature.com/articles/s41...

Congrats to all authors from me and Anthony 🎉 @dunnschool.bsky.social Check out this animation made by talented PhD student @matthew-batisio.bsky.social 😆

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Reposted by David Mick

Manuel Thery @manuelthery.bsky.social · Jul 29

EMBL Cell Biology and Biophysics department is searching for a new director. A major position to lead this field in Europe and beyond.
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Head of the Cell Biology and Biophysics Unit

The European Molecular Biology Laboratory (EMBL) is Europe’s flagship life sciences organisation, and one of the world’s leading research institutions. An intergovernmental organisation of 29 Member S...

embl.wd103.myworkdayjobs.com

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Reposted by David Mick

Nature Portfolio @natureportfolio.nature.com · Jul 20

SNAP-tag is a widespread tool for labelling protein for bioimaging. An article published in Nature Chemical Biology presents SNAP-tag2 with increased labelling kinetics and brightness, which translates into a better performance in live-cell super-resolution imaging. go.nature.com/46fMIZd 🧪

This is figure 2 showing how SNAP-tag engineering is aiming for faster and brighter fluorescence labeling

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David Mick @mick-lab.bsky.social · Jul 13

Beautiful work on the development of protein kinase reporters. Congrats all! www.nature.com/articles/s41...

Molecular recording of cellular protein kinase activity with chemical labeling - Nature Chemical Biology

Molecular recorders based on kinase activity-dependent protein labeling track specific kinase activities to understand their link to cellular phenotypes in heterogeneous cell populations and in vivo.

www.nature.com

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Reposted by David Mick

FOR5547 Primary cilia dynamics @for5547.bsky.social · May 14

Grateful to be part of such a fantastic consortium! Huge thanks to our amazing coordinator Christina and to Silke for organizing an inspiring annual meeting in Jena. Latest new: we’ve got a new rising star on the team! #cilia

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David Mick @mick-lab.bsky.social · May 10

Looks beautiful, indeed. Say hi to John and Robin!

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Thiago Carvalho @cyrilpedia.bsky.social · May 3

'Reproductive-associated changes are also known to occur at the organ level, in particular, an increase in intestinal size during pregnancy and lactation has been observed in several mammals such as mice, rats, sheep, and pigs'
thenode.biologists.com/re-growing-a...

Re-growing adult organs: mothers do it best - the Node

Tomotsune Ameku tells the story behind the paper "Growth of the maternal intestine during reproduction"

thenode.biologists.com

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Reposted by David Mick

Mill_lab @cilialab.bsky.social · Apr 30

@sven-m-lange.bsky.social @alanbrownhms.bsky.social epic preprint dropped last night 🔥🔥🔥 #cilia #ift #ubiquitin #compartmentalization #signaling #GPCRs #AnticipationBuilding #SlowRead 🧪 www.biorxiv.org/content/10.1...

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Reposted by David Mick

Philippe Bastin's Lab @bastinlab.bsky.social · Apr 14

Dear cilia researchers, join us in the heart of the beautiful Vosges mountains to share your latest findings! This year, partnership with @for5547.bsky.social and keynote lectures by @micromotility.bsky.social and @mick-lab.bsky.social
Registration is now open www.cfc2025.conferences-pasteur.org

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David Mick @mick-lab.bsky.social · Apr 12

Congrats James! Well deserved!

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Reposted by David Mick

Henne lab @hennelab.bsky.social · Mar 27

Mark your calendars & repost! Join us for the 2026 FASEB Lipid Droplets Conference!

July 26-30, 2026 in beautiful Scottsdale, Arizona.

Best of all: The FASEB Lipid Droplet meeting is co-locating with the FASEB Phospholipid meeting. Two wonderful lipid communities brought together!

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David Mick @mick-lab.bsky.social · Mar 27

Congrats Pleasantine! Very well deserved!

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David Mick @mick-lab.bsky.social · Mar 23

Fantastic lineup again. Can't wait!

DGZ.bsky.social @dgz.bsky.social · Mar 22

Join us next week Tuesday for the #DGZ Focus Workshop on #membrane organization and #contactsites, at noon via zoom, organized by Katja Zieske and @buttnerlab.bsky.social 👩‍🔬🧬

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David Mick @mick-lab.bsky.social · Mar 22

I miss Freiburg. Should visit our fantastic collaborators there soon.

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Reposted by David Mick

Kathleen Bachynski @bachynski.bsky.social · Mar 18

“The Trump administration has canceled funding for an ongoing 30-year, nationwide study tracking patients with prediabetes and diabetes, researchers said, at a time when top officials have emphasized their determination to curb the incidence of such chronic conditions.”

NIH cancels funding for landmark diabetes study at a time of focus on chronic disease

The Trump administration has canceled funding for an ongoing 30-year, nationwide study tracking patients with prediabetes and diabetes, researchers said.

www.statnews.com

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Eric Topol @erictopol.bsky.social · Mar 13

More than 2 decades ago the PINK1 protein was found to be linked to Parkinson's disease, but its structure and how it was activated was not known. Until @science.org today. A triumph for cryo-EM and structural biology, introducing new targets for drug intervention.
www.science.org/doi/10.1126/...

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Reposted by David Mick

bioRxivpreprint @biorxivpreprint.bsky.social · Mar 12

A critical role for the ER Membrane Complex (EMC) in lipid droplet homeostasis https://www.biorxiv.org/content/10.1101/2025.03.10.642408v1

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