Lightnews — Scholar-powered news

Reposted by Surace Lab

Cluster of Excellence ImmunoSensation @immunosens.bsky.social · Aug 11

🚨 #Job alert! The group of Johannes Brägelmann at the Medical ClinicIII at the University Hospital in Bonn is offering 2 PhD positions:

1) PhD in Cancer Immunology
Link: www.immunosensation.de/opportunitie...

2) PhD in Spatial Cancer Biology
Link: www.immunosensation.de/opportunitie...

Apply now!

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Reposted by Surace Lab

Waggoner Lab @labwaggoner.bsky.social · Aug 7

Cysteinyl leukotrienes are important drivers of the anaphylactic response to ingested food antigens @science.org
Comment: www.science.org/doi/10.1126/...
on @rmedzhitov.bsky.social @stephanieeisen.bsky.social
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...

Opening the gateway to food-induced anaphylaxis

Cysteinyl leukotrienes are important drivers of the anaphylactic response to ingested food antigens

www.science.org

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Reposted by Surace Lab

Christian Frezza @frezzalab.bsky.social · Jul 3

Microbial riboflavin inhibits ceramide synthase 3 to lower ceramide (d18:1/26:0) and delay colorectal cancer progression: Cell Metabolism www.cell.com/cell-metabol...

Microbial riboflavin inhibits ceramide synthase 3 to lower ceramide (d18:1/26:0) and delay colorectal cancer progression

This study identifies C26 ceramide and CERS3 as critical factors in colorectal cancer progression, which is modulated by microbial metabolite riboflavin. C26 ceramide directly activates EGFR, and the ...

www.cell.com

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Reposted by Surace Lab

Jeff Mold @jeffmold.bsky.social · Jul 3

Woohoo! From superstars ionut and Marta in the Frisén lab! www.science.org/doi/10.1126/... can’t wait to see what the anti-neurogenesis folks say about it 😃

Identification of proliferating neural progenitors in the adult human hippocampus

Continuous adult hippocampal neurogenesis is involved in memory formation and mood regulation but is challenging to study in humans. Difficulties finding proliferating progenitor cells called into que...

www.science.org

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Reposted by Surace Lab

Eric Topol @erictopol.bsky.social · Jul 2

We are all somatic mutation mosaics.
"There are trillions of cells in a human body and so the total number of somatic mutations acquired in a single individual may well exceed quadrillions, millions of times the size of the human genome."
@nature.com
nature.com/articles/s41...

The Somatic Mosaicism across Human Tissues Network - Nature

The Somatic Mosaicism across Human Tissues Network aims to create a reference catalogue of somatic mosaicism across different tissues and cells within individuals.

nature.com

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Aneesha Dasgupta @aneedasgupta.bsky.social · Jul 2

Excited to share our new work in PDAC Cachexia. This work demonstrated that addition of factors like advanced age in murine models can uncover signatures that might have been obscured in other models.
Grateful for @jdoles.bsky.social ‘s mentorship and support!
Looking forward to all feedback :)

Rockefeller University Press @rupress.org · Jul 2

Cachexia is a devastating cancer comorbidity that impacts numerous cancer outcomes. In @jem.org, @aneedasgupta.bsky.social, @jdoles.bsky.social et al describe a novel metabolic pathway/target w/ clinical implications for the treatment of cachectic #PancreaticCancer rupress.org/jem/article/...

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Reposted by Surace Lab

Kurianlab @kurianlab.bsky.social · Mar 7

www.science.org/doi/10.1126/...

Tour de force by Barna Lab

A subcellular map of translational machinery composition and regulation at the single-molecule level

Millions of ribosomes are packed within mammalian cells, yet we lack tools to visualize them in toto and characterize their subcellular composition. In this study, we present ribosome expansion micros...

www.science.org

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Surace Lab @suracelab.bsky.social · Feb 27

@philippstrobl.bsky.social @nsssusanna.bsky.social @dhruvishah.bsky.social lina, Nehir and Ivan

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Surace Lab @suracelab.bsky.social · Feb 27

I feel very lucky that science is my job… I feel even better when I think about the amazing people that I get to see everyday !
Ladies and gentleman…..The fairies 🧚🏻 from @labwilhelm.bsky.social and the fluorochromes (+ bad comp) from our @suracelab.bsky.social !

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Reposted by Surace Lab

Surace Lab @suracelab.bsky.social · Jan 14

🚨 Job alert 🚨
1 PhD + 1 Technician
Our lab is looking for motivated candidates interested in understanding the impact of diets and lifestyle on tumor development, anti-tumor immunity and metastasis! Apply and join our team!
Info below 👇

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Reposted by Surace Lab

Cluster of Excellence ImmunoSensation @immunosens.bsky.social · Jan 15

🚨 Open #position! The group of Christoph Wilhelm at the University Hospital Bonn is looking for a

Postdoctoral fellow (m/f/d) – metabolic and nutritional regulation of immunity

Application deadline is February 10!

Visit our website for more information.

#job #postdoc #science #immunology

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Reposted by Surace Lab

Sarah Ross @sarahhross.bsky.social · Jan 16

#Immunology out now @science.org

ILC2s contribute to glucose homeostasis. Neurons that innervate the gut from areas of the brain associated with glucose sensing can stimulate ILC2s in the gut to relocate to the pancreas upon fasting.

https://buff.ly/42iBst0

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Surace Lab @suracelab.bsky.social · Jan 14

🚨 Job alert 🚨
1 PhD + 1 Technician
Our lab is looking for motivated candidates interested in understanding the impact of diets and lifestyle on tumor development, anti-tumor immunity and metastasis! Apply and join our team!
Info below 👇

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Reposted by Surace Lab

Christian Frezza @frezzalab.bsky.social · Dec 29

Effects of Aging on Glucose and Lipid Metabolism in Mice

congrats @mvhlab.bsky.social !

onlinelibrary.wiley.com/doi/10.1111/...

Effects of Aging on Glucose and Lipid Metabolism in Mice

Lien et al. report a characterization of metabolism with aging across three different strains of mice. They find that glucose metabolism is robust during healthy aging; however, aging tissues exhibit....

onlinelibrary.wiley.com

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Reposted by Surace Lab

Christian Frezza @frezzalab.bsky.social · Dec 26

For those starting on BSKY and loving #metabolism and #mitochondria, the 2 starter packs have now been completed. 300 scientists working in this field are here to be followed! Happy Boxing Day

Starter pack 1: go.bsky.app/VavECSX

Starter pack 2: go.bsky.app/CH1MctZ

a stack of gift boxes with the words happy boxing day below

ALT: a stack of gift boxes with the words happy boxing day below

media.tenor.com

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Surace Lab @suracelab.bsky.social · Dec 20

@nsssusanna.bsky.social @philippstrobl.bsky.social @dhruvishah.bsky.social and Lina

Surace Lab @suracelab.bsky.social · Dec 20

What a great year for our group! Thanks guys for your constant support, the passion and the hard work you put to bring forward our ideas and projects, and also …. for being amazing Artists&chef pâtissier!

With a photo of the latest ArtAttack, we wish everybody merry Christmas and happy new year!

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Reposted by Surace Lab

Sarah Ross @sarahhross.bsky.social · Dec 19

#Immunology by First release now @science.org

Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection

https://buff.ly/3DjNQ1e

By Maria Canesso, @danmucida.bsky.social , @victora.bsky.social and colleagues.

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Reposted by Surace Lab

Adrian Liston @labliston.bsky.social · Dec 13

A very rare position for an immunology professorship at Cambridge. Something to think about!

www.jobs.cam.ac.uk/job/49381/

Associate Professor/Professor of Infection and/or Immunity - Job Opportunities - University of Cambridge

Associate Professor/Professor of Infection and/or Immunity in the Department of Pathology at the University of Cambridge.

www.jobs.cam.ac.uk

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Surace Lab @suracelab.bsky.social · Dec 12

inherited genetic alteration governs breast cancer metastasis .. interesting work on the hereditary basis of metastasis !

www.cell.com/cell/abstrac...

A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor

Characterization of a common germline variant in PCSK9 unveils a hereditary basis underlying breast cancer metastasis and suggests that PCSK9 inhibition therapy could be a promising strategy for breast cancer metastasis prevention.

www.cell.com

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Reposted by Surace Lab

Eric Topol @erictopol.bsky.social · Dec 12

Gearing up vs the potential of building "mirror life"
A looming danger of bioengineered reversed-chirality bacteria and microbes.
www.science.org/doi/10.1126/... @science.org

Confronting risks of mirror life

Broad discussion is needed to chart a path forward.

www.science.org

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Reposted by Surace Lab

Waggoner Lab @labwaggoner.bsky.social · Dec 12

Lipid-delivery of mRNA to placenta to treat pre-eclampsia
www.nature.com/articles/d41...
www.nature.com/articles/s41...

Lipid-delivery system could treat life-threatening pregnancy complication

Testing lipid nanoparticles for pre-eclampsia treatment.

www.nature.com

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Surace Lab @suracelab.bsky.social · Dec 12

Brava brava Elvira !

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Reposted by Surace Lab

BK. Titanji @boghuma.bsky.social · Dec 12

Wow just wow. I did not have on my bingo card an mRNA therapeutic for treating pre eclampsia. A VEGF tropic mRNA resolved maternal hypertension until pregnancy in a mouse model of the condition. Really fascinating science.
🧪
www.nature.com/articles/s41...

Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia - Nature

A platform for mRNA lipid nanoparticle delivery to the placenta to treat pre-eclampsia is shown to improve fetal and maternal health in mice and has potential clinical applications in obstetric d...

www.nature.com

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Reposted by Surace Lab

Rod Rahimi @rodrahimi.bsky.social · Nov 29

Friends, it's fun to see the #immunology community continue to grow! I created a 4th Starter Pack to help folks find each other. If you're an immunologist and you don't see yourself on the lists, let me know 🧪

go.bsky.app/PY5tCas

go.bsky.app/FmERUoD

go.bsky.app/6aT6qDS

go.bsky.app/QSEPDoj

Rod Rahimi @rodrahimi.bsky.social · Nov 19

Friends, the second #immunology starter pack filled in 3 days! I started a third to help folks new to BlueSky rebuild their network

Below are the links

If you're an immunologist and I have missed you so far, let me know 🧪

go.bsky.app/PY5tCas

go.bsky.app/FmERUoD

go.bsky.app/6aT6qDS

Rod Rahimi @rodrahimi.bsky.social · Nov 15

Wonderful to see the #immunology community growing here.

The first starter pack is full (they cap at 150), so I created a second one. Let me know if you'd like to be added

go.bsky.app/PY5tCas

go.bsky.app/FmERUoD

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