STEMCELL Science News
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A complete resource for the latest discoveries in cell biology, from organoids to immunology. Brought to you by STEMCELL Technologies.
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Science News by @stemcell.com offers 20 regular newsletters with the latest peer-reviewed research, reviews, and industry news delivered straight to your inbox.
💌 Subscribe here: https://bit.ly/47lRBjq
Reposted by STEMCELL Science News
Happy Holidays from the CISR! May all your days and fluorophores be BRIGHT. #MicroscopyMonday
December 22, 2025 at 10:24 PM
Happy Holidays from the CISR! May all your days and fluorophores be BRIGHT. #MicroscopyMonday
Reposted by STEMCELL Science News
Happy Holidays from our team!
December 23, 2025 at 1:13 PM
Happy Holidays from our team!
❄️ Happy Holidays!
Our team will be away next week, so there will be a pause in our regular content.
📯 We'll be back the week of January 5th to deliver newsletters and daily posts.
Our team will be away next week, so there will be a pause in our regular content.
📯 We'll be back the week of January 5th to deliver newsletters and daily posts.
December 22, 2025 at 9:13 PM
❄️ Happy Holidays!
Our team will be away next week, so there will be a pause in our regular content.
📯 We'll be back the week of January 5th to deliver newsletters and daily posts.
Our team will be away next week, so there will be a pause in our regular content.
📯 We'll be back the week of January 5th to deliver newsletters and daily posts.
Check out this new study from Dr. Tanya Stoyanova's lab! 🥼
Dr. Alifiani Hartono and team demonstrate that CDC7 is a regulator of tumor progression in #prostate cancer and represents new therapeutic target in advanced prostate cancer. 💊
🔗 https://go.nature.com/3KTvwQQ
Dr. Alifiani Hartono and team demonstrate that CDC7 is a regulator of tumor progression in #prostate cancer and represents new therapeutic target in advanced prostate cancer. 💊
🔗 https://go.nature.com/3KTvwQQ
December 19, 2025 at 4:47 PM
Check out this new study from Dr. Tanya Stoyanova's lab! 🥼
Dr. Alifiani Hartono and team demonstrate that CDC7 is a regulator of tumor progression in #prostate cancer and represents new therapeutic target in advanced prostate cancer. 💊
🔗 https://go.nature.com/3KTvwQQ
Dr. Alifiani Hartono and team demonstrate that CDC7 is a regulator of tumor progression in #prostate cancer and represents new therapeutic target in advanced prostate cancer. 💊
🔗 https://go.nature.com/3KTvwQQ
Reposted by STEMCELL Science News
Some fiery prefrontal cortical neurons projecting to the locus coeruleus that are labeled in the mouse brain
#FluorescenceFriday 🧠🔬🔥
Image credit to @rehg-j.bsky.social and the @lieberinstitute.bsky.social Circuits Team
#FluorescenceFriday 🧠🔬🔥
Image credit to @rehg-j.bsky.social and the @lieberinstitute.bsky.social Circuits Team
December 19, 2025 at 2:28 PM
Some fiery prefrontal cortical neurons projecting to the locus coeruleus that are labeled in the mouse brain
#FluorescenceFriday 🧠🔬🔥
Image credit to @rehg-j.bsky.social and the @lieberinstitute.bsky.social Circuits Team
#FluorescenceFriday 🧠🔬🔥
Image credit to @rehg-j.bsky.social and the @lieberinstitute.bsky.social Circuits Team
Dr. Masoud Manjili and collaborators identify Bcl-xL as a central survival factor in chemotherapy-induced dormancy.
They suggest that targeted systemic delivery of A-1331852 may eradicate disseminated dormant cells. #TNBC
🔗 https://go.nature.com/4p5bUau
They suggest that targeted systemic delivery of A-1331852 may eradicate disseminated dormant cells. #TNBC
🔗 https://go.nature.com/4p5bUau
December 19, 2025 at 12:09 AM
Dr. Masoud Manjili and collaborators identify Bcl-xL as a central survival factor in chemotherapy-induced dormancy.
They suggest that targeted systemic delivery of A-1331852 may eradicate disseminated dormant cells. #TNBC
🔗 https://go.nature.com/4p5bUau
They suggest that targeted systemic delivery of A-1331852 may eradicate disseminated dormant cells. #TNBC
🔗 https://go.nature.com/4p5bUau
Love the #bacteriophage cheese board! 😂
Nature asked readers about their favorite scientific gifts. Here’s what they said.
What is your favorite scientific gift? 🧪
What is your favorite scientific gift? 🧪
The gift that shaped my career in science
Nature asked about your most memorable scientific gifts. You delivered.
go.nature.com
December 18, 2025 at 5:49 PM
Love the #bacteriophage cheese board! 😂
Reposted by STEMCELL Science News
Very pleased to share our new review "The Evolving Landscape of Brain Metastasis" in @cp-trendscancer.bsky.social 🧠🔬🧪
Grateful to an outstanding team of co-authors, all pioneers in the #brain #metastasis field and to @valientelab.bsky.social for co-leading this 🙏🏻
Link: www.cell.com/trends/cance...
Grateful to an outstanding team of co-authors, all pioneers in the #brain #metastasis field and to @valientelab.bsky.social for co-leading this 🙏🏻
Link: www.cell.com/trends/cance...
December 17, 2025 at 4:49 PM
Very pleased to share our new review "The Evolving Landscape of Brain Metastasis" in @cp-trendscancer.bsky.social 🧠🔬🧪
Grateful to an outstanding team of co-authors, all pioneers in the #brain #metastasis field and to @valientelab.bsky.social for co-leading this 🙏🏻
Link: www.cell.com/trends/cance...
Grateful to an outstanding team of co-authors, all pioneers in the #brain #metastasis field and to @valientelab.bsky.social for co-leading this 🙏🏻
Link: www.cell.com/trends/cance...
#Integrin α3 is implicated in #ADHD and other neurodevelopmental disorders.
A study in Molecular Psychiatry identifies hippocampal AMPAR regulation as a key pathway through which ITGA3 influences ADHD-related phenotypes.
https://go.nature.com/4aiBN2P
A study in Molecular Psychiatry identifies hippocampal AMPAR regulation as a key pathway through which ITGA3 influences ADHD-related phenotypes.
https://go.nature.com/4aiBN2P
December 17, 2025 at 11:06 PM
#Integrin α3 is implicated in #ADHD and other neurodevelopmental disorders.
A study in Molecular Psychiatry identifies hippocampal AMPAR regulation as a key pathway through which ITGA3 influences ADHD-related phenotypes.
https://go.nature.com/4aiBN2P
A study in Molecular Psychiatry identifies hippocampal AMPAR regulation as a key pathway through which ITGA3 influences ADHD-related phenotypes.
https://go.nature.com/4aiBN2P
A group of scientists from Sun Yat-sen University show that as #BladderCancer progresses, matrix stiffness and tumor #stemness increase.
High matrix stiffness mediates β-catenin nuclear translocation by increasing the nuclear pore size.
💡 https://go.nature.com/4pEqerl
High matrix stiffness mediates β-catenin nuclear translocation by increasing the nuclear pore size.
💡 https://go.nature.com/4pEqerl
December 17, 2025 at 7:34 PM
A group of scientists from Sun Yat-sen University show that as #BladderCancer progresses, matrix stiffness and tumor #stemness increase.
High matrix stiffness mediates β-catenin nuclear translocation by increasing the nuclear pore size.
💡 https://go.nature.com/4pEqerl
High matrix stiffness mediates β-catenin nuclear translocation by increasing the nuclear pore size.
💡 https://go.nature.com/4pEqerl
Led by Drs. Jocelynn Pearl and Annette Marleau, scientists review clinical advancements in the understanding of the therapeutic properties of MSCs and their subpopulations, assessing the evidence supporting their use in #RegenerativeMedicine.
💡Read it here! bit.ly/48N2kmg
💡Read it here! bit.ly/48N2kmg
December 16, 2025 at 11:59 PM
Led by Drs. Jocelynn Pearl and Annette Marleau, scientists review clinical advancements in the understanding of the therapeutic properties of MSCs and their subpopulations, assessing the evidence supporting their use in #RegenerativeMedicine.
💡Read it here! bit.ly/48N2kmg
💡Read it here! bit.ly/48N2kmg
🧪 Dr. Justus Duyster and team found that the STAT5-activating oncogenes JAK2 p.V617F, FLT3-ITD, and BCR::ABL1 induce oncostatin M, which triggers disease progression and immunosuppression.
@sigtrans-sttt.bsky.social | https://go.nature.com/4q938t4
@sigtrans-sttt.bsky.social | https://go.nature.com/4q938t4
December 16, 2025 at 8:34 PM
🧪 Dr. Justus Duyster and team found that the STAT5-activating oncogenes JAK2 p.V617F, FLT3-ITD, and BCR::ABL1 induce oncostatin M, which triggers disease progression and immunosuppression.
@sigtrans-sttt.bsky.social | https://go.nature.com/4q938t4
@sigtrans-sttt.bsky.social | https://go.nature.com/4q938t4
Hot off the press in @natcomms.nature.com 🔥
Drs. Mads Hald Andersen and Inge Marie Svane report long-term outcomes from the MM1636 trial, which evaluates a peptide vaccine targeting IDO and PD-L1 in combination with nivolumab in patients with melanoma. 💊
https://go.nature.com/48SQ0RE
Drs. Mads Hald Andersen and Inge Marie Svane report long-term outcomes from the MM1636 trial, which evaluates a peptide vaccine targeting IDO and PD-L1 in combination with nivolumab in patients with melanoma. 💊
https://go.nature.com/48SQ0RE
December 16, 2025 at 12:12 AM
Hot off the press in @natcomms.nature.com 🔥
Drs. Mads Hald Andersen and Inge Marie Svane report long-term outcomes from the MM1636 trial, which evaluates a peptide vaccine targeting IDO and PD-L1 in combination with nivolumab in patients with melanoma. 💊
https://go.nature.com/48SQ0RE
Drs. Mads Hald Andersen and Inge Marie Svane report long-term outcomes from the MM1636 trial, which evaluates a peptide vaccine targeting IDO and PD-L1 in combination with nivolumab in patients with melanoma. 💊
https://go.nature.com/48SQ0RE
From the Abrams & Brentjens labs, scientists reported that IL-36γ armored CAR T cells eradicate primary solid tumors and enable rejection of rechallenged antigen-negative tumors.
📙 Learn more: https://bit.ly/4qf3o9S
📙 Learn more: https://bit.ly/4qf3o9S
December 15, 2025 at 11:06 PM
From the Abrams & Brentjens labs, scientists reported that IL-36γ armored CAR T cells eradicate primary solid tumors and enable rejection of rechallenged antigen-negative tumors.
📙 Learn more: https://bit.ly/4qf3o9S
📙 Learn more: https://bit.ly/4qf3o9S
This @pnas.org study found that prostaglandin E2(PGE2) produced in TME confers the tumor-infiltrating Tregs signature to #Tregs via its receptors, EP2 and EP4.
➡️ Read the full article here: bit.ly/4q2xahV
➡️ Read the full article here: bit.ly/4q2xahV
December 12, 2025 at 4:52 PM
This @pnas.org study found that prostaglandin E2(PGE2) produced in TME confers the tumor-infiltrating Tregs signature to #Tregs via its receptors, EP2 and EP4.
➡️ Read the full article here: bit.ly/4q2xahV
➡️ Read the full article here: bit.ly/4q2xahV
Drs. Michael Keller and Navid Djassemi examine advancements in virus-specific T cell manufacturing that broaden their accessibility to a wider range of viral infections and immunocompromised populations.
👉 Read their review in @bloodjournals.hematology.org bit.ly/4oJ1Qnd
👉 Read their review in @bloodjournals.hematology.org bit.ly/4oJ1Qnd
December 11, 2025 at 12:53 AM
Drs. Michael Keller and Navid Djassemi examine advancements in virus-specific T cell manufacturing that broaden their accessibility to a wider range of viral infections and immunocompromised populations.
👉 Read their review in @bloodjournals.hematology.org bit.ly/4oJ1Qnd
👉 Read their review in @bloodjournals.hematology.org bit.ly/4oJ1Qnd
In this study, scientists utilized androgenetic, parthenogenetic, and biparental hESCs and their neural derivatives to identify novel imprinted genes by analyzing their methylome and transcriptome profiles.
📖 Read more: https://bit.ly/452mvvr
📖 Read more: https://bit.ly/452mvvr
December 10, 2025 at 8:47 PM
In this study, scientists utilized androgenetic, parthenogenetic, and biparental hESCs and their neural derivatives to identify novel imprinted genes by analyzing their methylome and transcriptome profiles.
📖 Read more: https://bit.ly/452mvvr
📖 Read more: https://bit.ly/452mvvr
🧠 This study suggests that targeting the CCL2/CCR2/ERK1/2 pathway may help overcome chemoresistance in #glioblastomas caused by cancer-associated fibroblasts!
👉 https://go.nature.com/3XI0cHu
👉 https://go.nature.com/3XI0cHu
December 10, 2025 at 6:10 PM
🧠 This study suggests that targeting the CCL2/CCR2/ERK1/2 pathway may help overcome chemoresistance in #glioblastomas caused by cancer-associated fibroblasts!
👉 https://go.nature.com/3XI0cHu
👉 https://go.nature.com/3XI0cHu
🔬 Researchers investigated the involvement of cyclin B2 in pancreatic ductal adenocarcinoma growth and progression using glycolysis inhibitors in vivo and in vitro.
🔗 https://bit.ly/44gwTzD
🔗 https://bit.ly/44gwTzD
December 9, 2025 at 5:49 PM
🔬 Researchers investigated the involvement of cyclin B2 in pancreatic ductal adenocarcinoma growth and progression using glycolysis inhibitors in vivo and in vitro.
🔗 https://bit.ly/44gwTzD
🔗 https://bit.ly/44gwTzD
💓 Scientists with Dr. Nobuaki Fukuma at @columbiauniversity.bsky.social investigated whether and how #cardiomyocyte NO-sensitive soluble guanylyl cyclase mediates female-specific, adaptive right ventricular pressure-overload remodeling.
👉 https://bit.ly/3WYQdx2
👉 https://bit.ly/3WYQdx2
December 9, 2025 at 12:11 AM
💓 Scientists with Dr. Nobuaki Fukuma at @columbiauniversity.bsky.social investigated whether and how #cardiomyocyte NO-sensitive soluble guanylyl cyclase mediates female-specific, adaptive right ventricular pressure-overload remodeling.
👉 https://bit.ly/3WYQdx2
👉 https://bit.ly/3WYQdx2
Researchers found that isoflurane facilitates hemispheric lateralization in BBB permeability, leading to different responses between the left and right hemispheres. 🧠
📖 https://bit.ly/3Yho4lq
📖 https://bit.ly/3Yho4lq
December 8, 2025 at 11:55 PM
Researchers found that isoflurane facilitates hemispheric lateralization in BBB permeability, leading to different responses between the left and right hemispheres. 🧠
📖 https://bit.ly/3Yho4lq
📖 https://bit.ly/3Yho4lq
Reposted by STEMCELL Science News
Astrocytes make up a quarter of all brain cells and are emerging as key players in #neuroskyence research. Take a look at how scientists have discovered astrocytes' role in memory, learning, and other brain functions. 🧠
The ‘silent’ brain cells that shape our behaviour, memory and health
Astrocytes make up one-quarter of the brain, but researchers are only now realizing their true value.
www.nature.com
December 5, 2025 at 5:08 PM
Astrocytes make up a quarter of all brain cells and are emerging as key players in #neuroskyence research. Take a look at how scientists have discovered astrocytes' role in memory, learning, and other brain functions. 🧠
Reposted by STEMCELL Science News
December 5, 2025 at 7:19 PM
Reposted by STEMCELL Science News
It’s #FluorescenceFriday !
Expression of synapsin-EGFP in neurons in one of our organoid models 🧠
Expression of synapsin-EGFP in neurons in one of our organoid models 🧠
December 5, 2025 at 8:37 PM
It’s #FluorescenceFriday !
Expression of synapsin-EGFP in neurons in one of our organoid models 🧠
Expression of synapsin-EGFP in neurons in one of our organoid models 🧠