Steph Cragg
@stephcragg.bsky.social
1.7K followers
180 following
9 posts
Neuroscientist heading the Cragglab!
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Reposted by Steph Cragg
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Steph Cragg
@stephcragg.bsky.social
· May 19
Reposted by Steph Cragg
Reposted by Steph Cragg
Reposted by Steph Cragg
The Guardian
@theguardian.com
· Apr 9
US scientists create most comprehensive circuit diagram of mammalian brain
3D map of a cubic millimetre of mouse brain reveals half a billion synapses and 5.4km of neuronal wiring
The most comprehensive circuit diagram of neurons in a mammalian brain has been created by scientists, providing groundbreaking insights into the mystery of how the brain works.
The map is of a speck of a mouse’s visual cortex, smaller than a grain of sand, and traces the structure of 84,000 neurons linked by half a billion synapses and approximately 5.4km of neuronal wiring. The 3D reconstruction of the cubic millimetre of brain is helping uncover how the brain is organised and how different cell types work together, and could have implications for the understanding of intelligence, consciousness and neuronal conditions such as Alzheimer’s, Parkinson’s, autism and schizophrenia. Continue reading...
www.theguardian.com
Reposted by Steph Cragg
Steph Cragg
@stephcragg.bsky.social
· Mar 17
Cortical Control of Striatal Dopamine Transmission via Striatal Cholinergic Interneurons
Abstract. Corticostriatal regulation of striatal dopamine (DA) transmission has long been postulated, but ionotropic glutamate receptors have not been loca
academic.oup.com
Steph Cragg
@stephcragg.bsky.social
· Mar 17
Cortical Control of Striatal Dopamine Transmission via Striatal Cholinergic Interneurons
Abstract. Corticostriatal regulation of striatal dopamine (DA) transmission has long been postulated, but ionotropic glutamate receptors have not been loca
academic.oup.com
Steph Cragg
@stephcragg.bsky.social
· Mar 17
YanFeng Zhang
@yanfengzhang.bsky.social
· Mar 17
An axonal brake on striatal dopamine output by cholinergic interneurons - Nature Neuroscience
Cholinergic interneurons act at nicotinic receptors to depress dopamine release, interrupting its relationship to dopamine neuron firing and supporting an inverse scaling of dopamine release according...
www.nature.com
Reposted by Steph Cragg
Reposted by Steph Cragg
Reposted by Steph Cragg
Steph Cragg
@stephcragg.bsky.social
· Nov 21
Steph Cragg
@stephcragg.bsky.social
· Nov 19
Rapid modulation of striatal cholinergic interneurons and dopamine release by satellite astrocytes
Nature Communications - Astrocytes perform intriguing roles in neural circuits. Here, the authors show that in striatum, astrocytes adopt a satellite-like proximity to cholinergic interneurons,...
rdcu.be
Steph Cragg
@stephcragg.bsky.social
· Nov 19
Reposted by Steph Cragg