Supreet
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supreetsaini.bsky.social
Supreet
@supreetsaini.bsky.social
Interested in microbial evolution, genetics of adaptation & speciation. Faculty at Indian Institute of Technology Bombay, India

https://sites.google.com/view/esmlab/home
Curious about how evolution takes place? Are you looking for a "first-course" in the subject?

My book, Fundamentals of Evolutionary Biology (CRC Press), takes a microbe-first approach and explains how molecular and cellular processes drive evolution.
October 13, 2025 at 5:14 AM
Reposted by Supreet
NEW SPECIAL ISSUE JUST RELEASED!

Sex unfolded: sex, asex, sexes. Read the introductory editorial by Guest Editors D. Roze, S Glemin, @thomaslenormand.bsky.social & K. Van Doninck here: academic.oup.com/jeb/issue/38/7

Fantastic cover art by Caroline Blanc.
Volume 38 Issue 7 | Journal of Evolutionary Biology | Oxford Academic
Journal of Evolutionary Biology
academic.oup.com
August 4, 2025 at 10:21 AM
Reposted by Supreet
Registration is open for the Microbial Genomics of Eukaryotes meeting in Glasgow! This event will showcase diverse scientific achievements in eukaryotic genome research. Register now and submit your abstract by 12 August: microb.io/MicroGenomic...
June 20, 2025 at 7:01 AM
Reposted by Supreet
“Tomato is the mother of potato.” scim.ag/4mheKrH
Thank ketchup for your French fries
Interbreeding with tomatoes 9 million years ago gave potatoes the genes to develop tubers
scim.ag
July 31, 2025 at 4:01 PM
How does packaging and presentation of a resource impact the evolutionary trajectory of a population?

Read our latest work at bmcecolevol.biomedcentral.com/articles/10....

(and www.biorxiv.org/content/10.1...)
Resource presentation dictates genetic and phenotypic adaptation in yeast - BMC Ecology and Evolution
Background Environments shape adaptive trajectories of populations, often leading to adaptive parallelism in identical, and divergence in different environments. However, how does the likelihood of th...
surl.li
April 16, 2025 at 6:24 AM
Reposted by Supreet
About fifty years ago, NASA strapped a message in a bottle to a rocket and flung it into the deep dark
It wasn’t supposed to go this far, but it did. Long past its mission, it’s still out there so far away now that a simple hello takes a day to reach it, and another day to hear if it says hello back
March 12, 2025 at 5:04 AM
Reposted by Supreet
Two (!) perspective pieces published today involving people from our lab! @adelpanta.bsky.social on spatial patterning in microbial communities www.nature.com/articles/s41... and @salazarafra.bsky.social on microbial communities as evolutionary individuals www.sciencedirect.com/science/arti...
Disentangling the feedback loops driving spatial patterning in microbial communities - npj Biofilms and Microbiomes
npj Biofilms and Microbiomes - Disentangling the feedback loops driving spatial patterning in microbial communities
www.nature.com
February 20, 2025 at 2:41 PM
Reposted by Supreet
I'm so happy that I can finally share the results of my first postdoc paper with @baym.lol!!! Turns out plasmids are an amazing system to study multi-scale evolution and we can track within-cell and between-cell dynamics!
(1/n) www.biorxiv.org/content/earl...
Intracellular competition shapes plasmid population dynamics
Conflicts between levels of biological organization are central to evolution, from populations of multicellular organisms to selfish genetic elements in microbes. Plasmids are extrachromosomal, self-r...
www.biorxiv.org
February 21, 2025 at 8:36 PM
Reposted by Supreet
Happy 37th birthday to the LTEE!
the-ltee.org/history/
History – The Long-Term Evolution Experiment
the-ltee.org
February 24, 2025 at 3:39 PM
Why do mutations exhibit predictable patterns of mutation effects?

In our latest work, we develop a toy model of bacterial growth to understand the mechanistic basis of global epistasis.

We would love to hear feedback!
February 7, 2025 at 10:10 AM
Reposted by Supreet
New comment on paper by Andreas Wagner on “evolvability-enhancing mutations.” I talk about the paper, and bigger issues in the study of evolvability.
https://www.nature.com/articles/s41467-023-41914-2
Mutations that enhance evolvability may open doors to faster adaptation - Nature Communications
A recent study demonstrated the existence of mutations that facilitate access to efficient evolutionary solutions. Here I discuss the implications of this finding and the potential to open a new chapter in the study of evolvability.
www.nature.com
October 11, 2023 at 2:41 PM
Reposted by Supreet
Over 30 prominent scientists call for a ban on the creation of a "mirror cell"--a microbe made of molecules that are mirror images of their natural forms. It could cause a mind-boggling global disaster. Here's my story [gift link] 🧪https://nyti.ms/3OUCXp6
A ‘Second Tree of Life’ Could Wreak Havoc, Scientists Warn (Gift Article)
Research on so-called mirror cells, which defy fundamental properties of living organisms, should be prohibited as too dangerous, biologists said.
nyti.ms
December 12, 2024 at 8:04 PM
Reposted by Supreet
We identified protein domains in LUCA (Last Universal Common Ancestor). Their distinctive amino acid usage reveals the order amino acids were added to the genetic code, based mostly on size. Older proteins hint at earlier alternative codes. 1/15 @seekingluca.bsky.social www.pnas.org/doi/10.1073/...
Order of amino acid recruitment into the genetic code resolved by last universal common ancestor’s protein domains | PNAS
The current “consensus” order in which amino acids were added to the genetic code is based on potentially biased criteria, such as the absence of s...
www.pnas.org
December 12, 2024 at 3:43 PM