SyNergy - Munich Cluster for Systems Neurology
@synergy-munich.bsky.social
SyNergy studies how complex neurological diseases like Alzheimer's, Parkinson's, stroke, and MS develop. By exploring shared mechanisms with a systems neurology approach, researchers aim to uncover new therapies. Funded by the DFG since 2012.
🏆 👏 Congratulations to our member Arthur Liesz @isd-research.bsky.social for receiving an ERC consolidator grant for his project: TRAINED - The Role of Trained Immunity in Brain-Body Communication and Secondary Organ Dysfunction.
🔗 Read more on our website: synergy-munich.de/news-events/...
🔗 Read more on our website: synergy-munich.de/news-events/...
December 9, 2025 at 1:32 PM
🏆 👏 Congratulations to our member Arthur Liesz @isd-research.bsky.social for receiving an ERC consolidator grant for his project: TRAINED - The Role of Trained Immunity in Brain-Body Communication and Secondary Organ Dysfunction.
🔗 Read more on our website: synergy-munich.de/news-events/...
🔗 Read more on our website: synergy-munich.de/news-events/...
Reposted by SyNergy - Munich Cluster for Systems Neurology
My research at @isd-research.bsky.social, @lmumuenchen.bsky.social, @synergy-munich.bsky.social focused on more physiological, human-based models that better reflect actual disease processes - and thus contribute to the global effort towards more effective dementia treatments tinyurl.com/3thjnvzs
Die Moleküle des Vergessens - Wie experimentelle menschliche Gehirnzellen den Weg zu Demenztherapien ebnen können
Angelika Dannert, PhD, Ludwig-Maximilians-Universität München
tinyurl.com
December 7, 2025 at 11:53 AM
My research at @isd-research.bsky.social, @lmumuenchen.bsky.social, @synergy-munich.bsky.social focused on more physiological, human-based models that better reflect actual disease processes - and thus contribute to the global effort towards more effective dementia treatments tinyurl.com/3thjnvzs
Congratulations @angelikadannert.bsky.social 👏
She did it! Huge congrats to @angelikadannert.bsky.social from our lab, who received the @koerber-ip.bsky.social DSP award for the best biomedical research thesis in Germany, directly from Julia Klöckner, head of the German parliament @bundestag.de!!! 🍾
December 8, 2025 at 2:53 PM
Congratulations @angelikadannert.bsky.social 👏
You can currently find us at #SfN25 Neuroscience 2025 in San Diego (Society for Neuroscience) as part of Neurocenters in Germany. If you're there too, let's connect - join us at booth 3917!
November 18, 2025 at 7:32 AM
You can currently find us at #SfN25 Neuroscience 2025 in San Diego (Society for Neuroscience) as part of Neurocenters in Germany. If you're there too, let's connect - join us at booth 3917!
👃 A reduced sense of smell can be one of the first signs of Alzheimer's disease. Researchers discovered that the brain's immune system plays a significant role, indicating that it may attack neuronal fibers essential for the sense of smell.
🔗Summary on our website: synergy-munich.de/news-events/...
🔗Summary on our website: synergy-munich.de/news-events/...
August 20, 2025 at 12:22 PM
👃 A reduced sense of smell can be one of the first signs of Alzheimer's disease. Researchers discovered that the brain's immune system plays a significant role, indicating that it may attack neuronal fibers essential for the sense of smell.
🔗Summary on our website: synergy-munich.de/news-events/...
🔗Summary on our website: synergy-munich.de/news-events/...
🏆 Our member Mikael Simons receives US$500,000 for a project to investigate disease mechanisms involving tau proteins. The funding is part of the international program „Tauopathy Challenge Workshop 2025“.
🔗 Read more at @dzne.science: www.dzne.de/en/im-fokus/...
🔗 Read more at @dzne.science: www.dzne.de/en/im-fokus/...
August 19, 2025 at 8:47 AM
🏆 Our member Mikael Simons receives US$500,000 for a project to investigate disease mechanisms involving tau proteins. The funding is part of the international program „Tauopathy Challenge Workshop 2025“.
🔗 Read more at @dzne.science: www.dzne.de/en/im-fokus/...
🔗 Read more at @dzne.science: www.dzne.de/en/im-fokus/...
👇Meet our member Angelika Harbauer @harbauerlab.bsky.social
Our latest Cell Scientist to Watch is Angelika Harbauer @harbauerlab.bsky.social. In this interview we learn more about Angelika’s career path, her thoughts on mentorship and how studying improv theatre helped her presentation skills.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
July 21, 2025 at 8:16 AM
👇Meet our member Angelika Harbauer @harbauerlab.bsky.social
🧠 A team of researchers led by Monika Leischner-Brill and Thomas Misgeld discovered that tubulin polyglutamylation plays an important role in synaptic remodeling by tagging microtubules for severing.
🔗Read a summary of the study on our website: synergy-munich.de/news-events/...
🔗Read a summary of the study on our website: synergy-munich.de/news-events/...
July 9, 2025 at 8:30 AM
🧠 A team of researchers led by Monika Leischner-Brill and Thomas Misgeld discovered that tubulin polyglutamylation plays an important role in synaptic remodeling by tagging microtubules for severing.
🔗Read a summary of the study on our website: synergy-munich.de/news-events/...
🔗Read a summary of the study on our website: synergy-munich.de/news-events/...
💭 “The most important thing for an early career researcher is to have good mentors. Ideally, this kind of a mentoring relationship is something that will naturally develop between the doctoral researcher and their supervisor."
👉 Interview w/ @haasslab.bsky.social at UEF: www.uef.fi/en/article/c...
👉 Interview w/ @haasslab.bsky.social at UEF: www.uef.fi/en/article/c...
Community is key for the research career
“One absolutely can change their research topic after the PhD. Indeed, it is essential to adopt new perspectives and methods during the post-doc phase,” said Professor Christian Haass, speaking at the...
www.uef.fi
June 18, 2025 at 8:17 AM
💭 “The most important thing for an early career researcher is to have good mentors. Ideally, this kind of a mentoring relationship is something that will naturally develop between the doctoral researcher and their supervisor."
👉 Interview w/ @haasslab.bsky.social at UEF: www.uef.fi/en/article/c...
👉 Interview w/ @haasslab.bsky.social at UEF: www.uef.fi/en/article/c...
🏆 👏 Congratulations to our members Dieter Edbauer, Thomas Korn, and Christian Weber who each received the prestigious ERC Advanced Grant from the European Research Council (ERC)!
🔗 Read more on our website: synergy-munich.de/scrivito/new...
🔗 Read more on our website: synergy-munich.de/scrivito/new...
June 18, 2025 at 7:21 AM
🏆 👏 Congratulations to our members Dieter Edbauer, Thomas Korn, and Christian Weber who each received the prestigious ERC Advanced Grant from the European Research Council (ERC)!
🔗 Read more on our website: synergy-munich.de/scrivito/new...
🔗 Read more on our website: synergy-munich.de/scrivito/new...
👏Congratulations Arthur Liesz! Liesz was awarded the prestigious ESO Scientific Excellence Award for his contributions to the understanding of stroke and neurovascular disease. The award was presented during the Presidential Session at the ESO Conference in Helsinki.
@isd-research.bsky.social
@isd-research.bsky.social
June 3, 2025 at 1:17 PM
👏Congratulations Arthur Liesz! Liesz was awarded the prestigious ESO Scientific Excellence Award for his contributions to the understanding of stroke and neurovascular disease. The award was presented during the Presidential Session at the ESO Conference in Helsinki.
@isd-research.bsky.social
@isd-research.bsky.social
Reposted by SyNergy - Munich Cluster for Systems Neurology
Microglia activation orchestrates CXCL10-mediated CD8+ T cell recruitment to promote aging-related white matter degeneration
@janos-groh.bsky.social @tum.de @synergy-munich.bsky.social @dzne.science
www.nature.com/articles/s41...
@janos-groh.bsky.social @tum.de @synergy-munich.bsky.social @dzne.science
www.nature.com/articles/s41...
Microglia activation orchestrates CXCL10-mediated CD8+ T cell recruitment to promote aging-related white matter degeneration - Nature Neuroscience
White matter aging leads to degenerative and inflammatory changes. Here the authors show that microglial dysfunction exacerbates glial CXCL10 expression, harmful CD8+ T cell recruitment, myelinated ax...
www.nature.com
May 22, 2025 at 4:26 PM
Microglia activation orchestrates CXCL10-mediated CD8+ T cell recruitment to promote aging-related white matter degeneration
@janos-groh.bsky.social @tum.de @synergy-munich.bsky.social @dzne.science
www.nature.com/articles/s41...
@janos-groh.bsky.social @tum.de @synergy-munich.bsky.social @dzne.science
www.nature.com/articles/s41...
👏 With our member Lisa-Ann Gerdes 👇
In a twin study, Max Planck researchers successfully characterized gut bacteria involved in #MultipleSclerosis and provided evidence of their pathogenicity. www.mpg.de/24685137/050... @mpiforbi.bsky.social
Multiple sclerosis: Triggers in the gut flora
Study of twins detects bacteria in the small intestine that play a role in the development of MS
www.mpg.de
May 14, 2025 at 8:00 AM
👏 With our member Lisa-Ann Gerdes 👇
🏃♂️➡️🏃♀️➡️ A team of 19 researchers, along with our managing director and Team Captain, Tobias Niemann, participated in the largest running event to raise funds for spinal cord injury research—the Wings for Life World Run.
More: synergy-munich.de/news-events/...
More: synergy-munich.de/news-events/...
May 6, 2025 at 11:02 AM
🏃♂️➡️🏃♀️➡️ A team of 19 researchers, along with our managing director and Team Captain, Tobias Niemann, participated in the largest running event to raise funds for spinal cord injury research—the Wings for Life World Run.
More: synergy-munich.de/news-events/...
More: synergy-munich.de/news-events/...
Reposted by SyNergy - Munich Cluster for Systems Neurology
Great to be at #Tau2025 in London, where @angelikadannert.bsky.social from the lab presents our human #iPSC model of Tauopathies in a packed poster session
April 24, 2025 at 3:11 PM
Great to be at #Tau2025 in London, where @angelikadannert.bsky.social from the lab presents our human #iPSC model of Tauopathies in a packed poster session
A study led by Anna-Sophia Wahl (@isd-research.bsky.social) reveals that the survival of place cells with stable coding for spatial information can be a strong predictor of positive cognitive outcomes following a #stroke.
🔗Read a summary on our website: synergy-munich.de/news-events/...
🔗Read a summary on our website: synergy-munich.de/news-events/...
April 23, 2025 at 11:19 AM
A study led by Anna-Sophia Wahl (@isd-research.bsky.social) reveals that the survival of place cells with stable coding for spatial information can be a strong predictor of positive cognitive outcomes following a #stroke.
🔗Read a summary on our website: synergy-munich.de/news-events/...
🔗Read a summary on our website: synergy-munich.de/news-events/...
Reposted by SyNergy - Munich Cluster for Systems Neurology
For his research project “Reprogrammed microglial cells as a therapeutic approach against Alzheimer's Disease” Dominik Paquet receives funding from the Alzheimer Forschung Initiative 🙌 @afi-ev.bsky.social
www.alzheimer-forschung.de/forschung/fo...
www.alzheimer-forschung.de/forschung/fo...
April 14, 2025 at 6:45 AM
For his research project “Reprogrammed microglial cells as a therapeutic approach against Alzheimer's Disease” Dominik Paquet receives funding from the Alzheimer Forschung Initiative 🙌 @afi-ev.bsky.social
www.alzheimer-forschung.de/forschung/fo...
www.alzheimer-forschung.de/forschung/fo...
Reposted by SyNergy - Munich Cluster for Systems Neurology
Interested in cellular mechanisms of cognitive decline after stroke? Check out this work in Nature communications: Anna-Sophia Wahl lab track the fate of individual neurons involved in spatial memory before + after multiple, distributed microstrokes using chronic 2photon imaging in-vivo. 👍
Brain-wide microstrokes affect the stability of memory circuits in the hippocampus
Nature Communications - To reveal cellular mechanisms of cognitive decline after stroke the authors established an experimental paradigm in mice monitoring individual nerve cells involved in...
rdcu.be
April 14, 2025 at 8:26 AM
Interested in cellular mechanisms of cognitive decline after stroke? Check out this work in Nature communications: Anna-Sophia Wahl lab track the fate of individual neurons involved in spatial memory before + after multiple, distributed microstrokes using chronic 2photon imaging in-vivo. 👍
A study led by @nfranzme.bsky.social and published in Molecular Neurodegeneration reveals that α-synuclein co-pathology is more prevalent in advanced #alzheimersdisease and that it accelerates amyloid-related tau accumulation.
🔗Find a summary on our website: synergy-munich.de/scrivito/new...
🔗Find a summary on our website: synergy-munich.de/scrivito/new...
April 7, 2025 at 11:57 AM
A study led by @nfranzme.bsky.social and published in Molecular Neurodegeneration reveals that α-synuclein co-pathology is more prevalent in advanced #alzheimersdisease and that it accelerates amyloid-related tau accumulation.
🔗Find a summary on our website: synergy-munich.de/scrivito/new...
🔗Find a summary on our website: synergy-munich.de/scrivito/new...
Join "Was Wissen schafft" next week for an exciting presentation by our member Jovica Ninkovic (@bmc-lmu.bsky.social)
🗓️8 April 2025, 7 PM
📍Hybrid: Campus Martinsried or Zoom
🎤"Gehirn in Bestform: Stammzellen für Plastizität und Regneration des Gehirns"
🔗 more info: www.bi.mpg.de/2739077/2025...
🗓️8 April 2025, 7 PM
📍Hybrid: Campus Martinsried or Zoom
🎤"Gehirn in Bestform: Stammzellen für Plastizität und Regneration des Gehirns"
🔗 more info: www.bi.mpg.de/2739077/2025...
April 2, 2025 at 10:08 AM
Join "Was Wissen schafft" next week for an exciting presentation by our member Jovica Ninkovic (@bmc-lmu.bsky.social)
🗓️8 April 2025, 7 PM
📍Hybrid: Campus Martinsried or Zoom
🎤"Gehirn in Bestform: Stammzellen für Plastizität und Regneration des Gehirns"
🔗 more info: www.bi.mpg.de/2739077/2025...
🗓️8 April 2025, 7 PM
📍Hybrid: Campus Martinsried or Zoom
🎤"Gehirn in Bestform: Stammzellen für Plastizität und Regneration des Gehirns"
🔗 more info: www.bi.mpg.de/2739077/2025...
Reposted by SyNergy - Munich Cluster for Systems Neurology
🧠 🏆 Congrats DZNE scientist Christian Haass
@haasslab.bsky.social On a recent gala in Paris, he was awarded the "Grand Prix Européen 2024" by the "Fondation Recherche Alzheimer" for his research on #Alzheimer's.
👉 youtu.be/kDe8nuGkn2E?...
@haasslab.bsky.social On a recent gala in Paris, he was awarded the "Grand Prix Européen 2024" by the "Fondation Recherche Alzheimer" for his research on #Alzheimer's.
👉 youtu.be/kDe8nuGkn2E?...
🎶Le Gala de la Fondation Recherche Alzheimer met à l’honneur les chercheurs🔬
YouTube video by Fondation Recherche Alzheimer
youtu.be
March 30, 2025 at 8:01 PM
🧠 🏆 Congrats DZNE scientist Christian Haass
@haasslab.bsky.social On a recent gala in Paris, he was awarded the "Grand Prix Européen 2024" by the "Fondation Recherche Alzheimer" for his research on #Alzheimer's.
👉 youtu.be/kDe8nuGkn2E?...
@haasslab.bsky.social On a recent gala in Paris, he was awarded the "Grand Prix Européen 2024" by the "Fondation Recherche Alzheimer" for his research on #Alzheimer's.
👉 youtu.be/kDe8nuGkn2E?...
A team led by Jürgen Bernhagen & Omar El Bounkari (@isd-research.bsky.social) improves our understanding of how inflammation in blood vessels is connected to liver problems in atherosclerotic diseases and suggests potential treatment pathways.
🔗More insights: synergy-munich.de/news-events/...
🔗More insights: synergy-munich.de/news-events/...
March 25, 2025 at 12:57 PM
A team led by Jürgen Bernhagen & Omar El Bounkari (@isd-research.bsky.social) improves our understanding of how inflammation in blood vessels is connected to liver problems in atherosclerotic diseases and suggests potential treatment pathways.
🔗More insights: synergy-munich.de/news-events/...
🔗More insights: synergy-munich.de/news-events/...
Reposted by SyNergy - Munich Cluster for Systems Neurology
Prof. Dr. Paquet (@paquetlab.bsky.social) von der LMU München und sein Team züchten Mikrogliazellen mit neuen Rezeptoren, die schädliche Eiweiße wie Amyloid-beta besser erkennen und beseitigen sollen. Mit dieser Strategie könnten die neuen Alzheimer-Therapien ergänzt werden. Mehr Infos im Video!
Demenz-Forscher Prof. Dr. Dominik Paquet
YouTube video by Alzheimer Forschung Initiative
www.youtube.com
March 6, 2025 at 7:50 AM
Prof. Dr. Paquet (@paquetlab.bsky.social) von der LMU München und sein Team züchten Mikrogliazellen mit neuen Rezeptoren, die schädliche Eiweiße wie Amyloid-beta besser erkennen und beseitigen sollen. Mit dieser Strategie könnten die neuen Alzheimer-Therapien ergänzt werden. Mehr Infos im Video!
💭 Our PhD & Postdoc reps initiated visits to our Technology Hubs for our researchers and kicked off with a visit to our Single-Cell and Spatial Transcriptome Hubs last week.
👋 Thanks Arek Kendirli, Janos Groh, Clara de la Rosa del Val, and Simon Frerich for hosting the first event of the series!
👋 Thanks Arek Kendirli, Janos Groh, Clara de la Rosa del Val, and Simon Frerich for hosting the first event of the series!
March 6, 2025 at 12:50 PM
💭 Our PhD & Postdoc reps initiated visits to our Technology Hubs for our researchers and kicked off with a visit to our Single-Cell and Spatial Transcriptome Hubs last week.
👋 Thanks Arek Kendirli, Janos Groh, Clara de la Rosa del Val, and Simon Frerich for hosting the first event of the series!
👋 Thanks Arek Kendirli, Janos Groh, Clara de la Rosa del Val, and Simon Frerich for hosting the first event of the series!
👋 Meet our PhD and Postdoc Representatives
💭 The voice of our PhD students and Postdocs. A point of contact for feedback, questions, criticism, and improvements. And they organize extracurricular activities! Meet @angelikadannert.bsky.social, Clara, Lis and Nathalie.
🔗 Read more: lnkd.in/dKtzshqr
💭 The voice of our PhD students and Postdocs. A point of contact for feedback, questions, criticism, and improvements. And they organize extracurricular activities! Meet @angelikadannert.bsky.social, Clara, Lis and Nathalie.
🔗 Read more: lnkd.in/dKtzshqr
February 18, 2025 at 1:25 PM
👋 Meet our PhD and Postdoc Representatives
💭 The voice of our PhD students and Postdocs. A point of contact for feedback, questions, criticism, and improvements. And they organize extracurricular activities! Meet @angelikadannert.bsky.social, Clara, Lis and Nathalie.
🔗 Read more: lnkd.in/dKtzshqr
💭 The voice of our PhD students and Postdocs. A point of contact for feedback, questions, criticism, and improvements. And they organize extracurricular activities! Meet @angelikadannert.bsky.social, Clara, Lis and Nathalie.
🔗 Read more: lnkd.in/dKtzshqr