Tania Wong
@taniawong.bsky.social
240 followers
440 following
15 posts
Assistant Professor & Chancellor Scholar
Department of Microbiology, Biochemistry and Molecular Genetics | Center for Immunity and Inflammation | Rutgers New Jersey Medical School
Host-pathogen interactions, innate immune and metabolic responses
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Reposted by Tania Wong
Ivan Zanoni
@lozanzi.bsky.social
· Aug 31
The source of dietary fat influences anti-tumour immunity in obese mice - Nature Metabolism
This study shows that animal-based high-fat diets accelerate tumour growth and impair anti-tumour response to melanoma in obese mice, whereas plant-based high-fat diets do not.
www.nature.com
Tania Wong
@taniawong.bsky.social
· Aug 12
Tania Wong
@taniawong.bsky.social
· Aug 12
Tania Wong
@taniawong.bsky.social
· Aug 8
Tania Wong
@taniawong.bsky.social
· Aug 1
Regulation of airway fumarate by host and pathogen promotes Staphylococcus aureus pneumonia - Nature Communications
This study reveals how the pathogen Staphylococcus aureus adapts to the lung microenvironment, rich in host metabolites fumarate and itaconate, by using a key enzyme, FumC, to support its metabolic fi...
www.nature.com
Tania Wong
@taniawong.bsky.social
· Jul 29
Expanding Institute, Growing Reach: i3D’s Symposium Shows Its Momentum
The Rutgers Health Institute for Infectious and Inflammatory Diseases uses a fast-expanding conference to trade fresh data, forge collaborations and spotlight new talent.
www.rutgers.edu
Tania Wong
@taniawong.bsky.social
· Jul 9
Reposted by Tania Wong
ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ
@nizet.bsky.social
· Jun 14
Antagonism as a foraging strategy in microbial communities
In natural habitats, nutrient availability limits bacterial growth. We discovered that bacteria can overcome this limitation by acquiring nutrients by lysing neighboring cells through contact-dependen...
www.science.org
Tania Wong
@taniawong.bsky.social
· Apr 19
Regulation of airway fumarate by host and pathogen promotes S. aureus pneumonia
Staphylococcus aureus is a leading cause of healthcare-associated pneumonia, contributing significantly to morbidity and mortality worldwide. As a ubiquitous colonizer of the upper respiratory tract, ...
www.biorxiv.org
Reposted by Tania Wong
Waggoner Lab
@labwaggoner.bsky.social
· Apr 18
Itaconate modulates immune responses via inhibition of peroxiredoxin 5 - Nature Metabolism
Itaconate is shown to non-covalently inhibit the antioxidant enzyme peroxiredoxin 5 in macrophages, thereby modulating the production of mitochondrial peroxide and enhancing the type I interferon prod...
www.nature.com
Reposted by Tania Wong
Reposted by Tania Wong
Reposted by Tania Wong
Ivan Zanoni
@lozanzi.bsky.social
· Feb 6
Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues
Mitochondrial damage is a hallmark of metabolic diseases, including diabetes, yet the consequences of compromised mitochondria in metabolic tissues are often unclear. Here, we report that dysfunctiona...
www.science.org
Reposted by Tania Wong
Ivan Zanoni
@lozanzi.bsky.social
· Feb 2
Cholesterol mobilization regulates dendritic cell maturation and the immunogenic response to cancer - Nature Immunology
To mature, dendritic cells collect and synthesize cholesterol to construct lipid nanodomains on their membranes. Obstructing this process impairs their ability to prime T cells.
doi.org
Reposted by Tania Wong
Waggoner Lab
@labwaggoner.bsky.social
· Jan 29
Prior vaccination prevents overactivation of innate immune responses during COVID-19 breakthrough infection
SARS-CoV-2 breakthrough infections in previously vaccinated individuals are characterized by reduced activation of innate immune responses.
www.science.org
Reposted by Tania Wong
Victor J. Torres
@torreslab.bsky.social
· Jan 17
Senior Scientist-Immunology, Vaccinology, Infection in Memphis, Tennessee | St. Jude Careers
St. Jude Careers is hiring a Senior Scientist-Immunology, Vaccinology, Infection in Memphis, Tennessee. Review all of the job details and apply today!
talent.stjude.org
Reposted by Tania Wong
Tania Wong
@taniawong.bsky.social
· Dec 20
Reposted by Tania Wong
ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ
@nizet.bsky.social
· Nov 27
Impaired development of memory B cells and antibody responses in humans and mice deficient in PD-1 signaling
Ogishi, Kitaoka, et al. examine humans deficient in PD-1 and PD-L1 as well as associated
mouse models and find that PD-1 and PD-L1 promote B cell memory and antibody responses
through both T cell-depe...
www.cell.com
Tania Wong
@taniawong.bsky.social
· Nov 23