Tim Frasier
@tfrasierdna.bsky.social
Population genetics, conservation genetics, whales, teaching, cycling
frasierlab.ca
frasierlab.ca
Reposted by Tim Frasier
Modeling the joint effects of genetic drift, mutation, and selection on loci that contribute to disease risk suggests that variation at many such loci is shaped more by their pleiotropic effects on non-disease traits than by their contribution to disease risk
Mutation–selection–drift balance models of complex diseases
Genetic variation is maintained through a balance of mutation, natural selection, and genetic drift. Although this general picture is well understood, it i
buff.ly
January 7, 2026 at 2:15 PM
Modeling the joint effects of genetic drift, mutation, and selection on loci that contribute to disease risk suggests that variation at many such loci is shaped more by their pleiotropic effects on non-disease traits than by their contribution to disease risk
Reposted by Tim Frasier
📖Published📖
Carter et al. present tidypopgen, a new R package for population genetic analysis of SNP data which combines existing methods for computational efficiency with an easy to use object structure 🧬 🌍 🧪
buff.ly/huubYjs
Carter et al. present tidypopgen, a new R package for population genetic analysis of SNP data which combines existing methods for computational efficiency with an easy to use object structure 🧬 🌍 🧪
buff.ly/huubYjs
January 6, 2026 at 10:15 AM
📖Published📖
Carter et al. present tidypopgen, a new R package for population genetic analysis of SNP data which combines existing methods for computational efficiency with an easy to use object structure 🧬 🌍 🧪
buff.ly/huubYjs
Carter et al. present tidypopgen, a new R package for population genetic analysis of SNP data which combines existing methods for computational efficiency with an easy to use object structure 🧬 🌍 🧪
buff.ly/huubYjs
Reposted by Tim Frasier
And we're live, Lecture A1 is online. Introduction to Bayesian workflow, generative models, estimands, estimators, estimates, error checking, beginnings of probability theory and Bayesian updating. www.youtube.com/watch?v=ztbY...
January 6, 2026 at 11:02 AM
And we're live, Lecture A1 is online. Introduction to Bayesian workflow, generative models, estimands, estimators, estimates, error checking, beginnings of probability theory and Bayesian updating. www.youtube.com/watch?v=ztbY...
Books read in 2025.
The Message, The Sympathizer, and White Fragility were all great and had a big impact on me. Vonnegut is fantastic. John Warner's new book is also great (particularly for teachers). Also re-read Moby Dick, a new version with lovely prints frequently throughout.
The Message, The Sympathizer, and White Fragility were all great and had a big impact on me. Vonnegut is fantastic. John Warner's new book is also great (particularly for teachers). Also re-read Moby Dick, a new version with lovely prints frequently throughout.
January 5, 2026 at 12:51 PM
Books read in 2025.
The Message, The Sympathizer, and White Fragility were all great and had a big impact on me. Vonnegut is fantastic. John Warner's new book is also great (particularly for teachers). Also re-read Moby Dick, a new version with lovely prints frequently throughout.
The Message, The Sympathizer, and White Fragility were all great and had a big impact on me. Vonnegut is fantastic. John Warner's new book is also great (particularly for teachers). Also re-read Moby Dick, a new version with lovely prints frequently throughout.
Reposted by Tim Frasier
The last Avian Hybrids story of 2025! 😀
Peaks and Pitfalls: How to avoid artefacts in demographic analyses
avianhybrids.wordpress.com/2025/12/31/p...
Based on the Current Biology paper by Leon Hilgers and his colleagues | #ornithology
Peaks and Pitfalls: How to avoid artefacts in demographic analyses
avianhybrids.wordpress.com/2025/12/31/p...
Based on the Current Biology paper by Leon Hilgers and his colleagues | #ornithology
Peaks and Pitfalls: How to avoid artefacts in demographic analyses
Changing default parameters can prevent false peaks in population size estimations.
avianhybrids.wordpress.com
December 31, 2025 at 11:17 AM
The last Avian Hybrids story of 2025! 😀
Peaks and Pitfalls: How to avoid artefacts in demographic analyses
avianhybrids.wordpress.com/2025/12/31/p...
Based on the Current Biology paper by Leon Hilgers and his colleagues | #ornithology
Peaks and Pitfalls: How to avoid artefacts in demographic analyses
avianhybrids.wordpress.com/2025/12/31/p...
Based on the Current Biology paper by Leon Hilgers and his colleagues | #ornithology
Reposted by Tim Frasier
Just gave my last talk of the year!
2025 was quite packed, I gave talks about:
- the age-period-cohort problem
- making rigorous causal inference more mainstream
- mediation analysis
- marginaleffects
- causal graphs (x10)
If you're curious, check out my slides here: juliarohrer.com/resources/
2025 was quite packed, I gave talks about:
- the age-period-cohort problem
- making rigorous causal inference more mainstream
- mediation analysis
- marginaleffects
- causal graphs (x10)
If you're curious, check out my slides here: juliarohrer.com/resources/
Resources
Here you can find a collection of things that may be helpful, including slide decks, a curated list of introductory papers and blog posts, as well as some infographics I have generated to explain v…
juliarohrer.com
December 18, 2025 at 12:38 PM
Just gave my last talk of the year!
2025 was quite packed, I gave talks about:
- the age-period-cohort problem
- making rigorous causal inference more mainstream
- mediation analysis
- marginaleffects
- causal graphs (x10)
If you're curious, check out my slides here: juliarohrer.com/resources/
2025 was quite packed, I gave talks about:
- the age-period-cohort problem
- making rigorous causal inference more mainstream
- mediation analysis
- marginaleffects
- causal graphs (x10)
If you're curious, check out my slides here: juliarohrer.com/resources/
We have an open tenure-track faculty position in our department for someone with a research program focusing on Cell Biology. See below
jobs.careerbeacon.com/details/assi...
jobs.careerbeacon.com/details/assi...
Saint Mary's University - Faculty Employment Opportunities is hiring an Assistant Professor - Biology - Halifax, NS
Could this be you? Click to find out more about this opportunity!
jobs.careerbeacon.com
December 17, 2025 at 5:27 PM
We have an open tenure-track faculty position in our department for someone with a research program focusing on Cell Biology. See below
jobs.careerbeacon.com/details/assi...
jobs.careerbeacon.com/details/assi...
Reposted by Tim Frasier
I had a wonderful conversation with @Trevor Aleo about my latest book, #Schoolishness: Alienated Education and the Quest for Authentic, Joyful Learning, and you can listen to us on his podcast, Conceptually Speaking. open.substack.com/pub/trevoral...
Dr. Susan Blum Talks Schoolishness and the Quest for Authentic, Joyful Learning
Listen now | In this episode of Conceptually Speaking, I sit down with Dr.
open.substack.com
November 25, 2025 at 12:28 PM
I had a wonderful conversation with @Trevor Aleo about my latest book, #Schoolishness: Alienated Education and the Quest for Authentic, Joyful Learning, and you can listen to us on his podcast, Conceptually Speaking. open.substack.com/pub/trevoral...
Reposted by Tim Frasier
There's a word for learning from evolution's inventions: bioinspiration. Here's my interactive story on the way animals and plants fuel technological creativity. Gift link: nyti.ms/4otNQyl
How Inventors Find Inspiration in Evolution (Gift Article)
Soft batteries and water-walking robots are among the many creations made possible by studying animals and plants.
nyti.ms
November 10, 2025 at 3:37 PM
There's a word for learning from evolution's inventions: bioinspiration. Here's my interactive story on the way animals and plants fuel technological creativity. Gift link: nyti.ms/4otNQyl
Reposted by Tim Frasier
The concept of "fitness" is central to evolutionary biology but it's not entirely worked out. There are multiple definitions, doubts about predictive power, problems with internal consistency. Here's a paper from last year attempting to solve some of these problems. doi.org/10.1093/evol...
November 5, 2025 at 2:27 PM
The concept of "fitness" is central to evolutionary biology but it's not entirely worked out. There are multiple definitions, doubts about predictive power, problems with internal consistency. Here's a paper from last year attempting to solve some of these problems. doi.org/10.1093/evol...
Calls for membership on COSEWIC subcommittees are now posted (including the marine mammals SSC)! It is incredibly rewarding to serve on these committees, not to mention the pleasure of working with such great people.
www.cosewic.ca/index.php/en...
www.cosewic.ca/index.php/en...
Cosewic - call-for-expressions-of-interest-as-specialist-subcommittee-members-including-early-career-biologists
www.cosewic.ca
October 30, 2025 at 1:29 PM
Calls for membership on COSEWIC subcommittees are now posted (including the marine mammals SSC)! It is incredibly rewarding to serve on these committees, not to mention the pleasure of working with such great people.
www.cosewic.ca/index.php/en...
www.cosewic.ca/index.php/en...
Reposted by Tim Frasier
Sharks absolutely get cancer, and people claiming otherwise are pseudoscientific grifters preying on the desperate.
Even if sharks did not get cancer, eating shark would not cure your cancer any more than eating LeBron James would make you better at basketball.
Even if sharks did not get cancer, eating shark would not cure your cancer any more than eating LeBron James would make you better at basketball.
October 30, 2025 at 9:27 AM
Sharks absolutely get cancer, and people claiming otherwise are pseudoscientific grifters preying on the desperate.
Even if sharks did not get cancer, eating shark would not cure your cancer any more than eating LeBron James would make you better at basketball.
Even if sharks did not get cancer, eating shark would not cure your cancer any more than eating LeBron James would make you better at basketball.
Reposted by Tim Frasier
Finally an #Idaho judge drops the hammer on a poaching ring with hefty jail sentences and lifetime hunting privileges suspended. The gasping from the sentencing courtroom gallery was the sound of privilege meeting justice. #idpol
www.kivitv.com/twin-falls/s...
www.kivitv.com/twin-falls/s...
Seven men sentenced to jail for multi-year poaching excursions south of Twin Falls
Seven men received jail sentences for an illegal deer hunting operation south of Twin Falls. Judge revokes lifetime hunting privileges.
www.kivitv.com
October 28, 2025 at 5:08 PM
Finally an #Idaho judge drops the hammer on a poaching ring with hefty jail sentences and lifetime hunting privileges suspended. The gasping from the sentencing courtroom gallery was the sound of privilege meeting justice. #idpol
www.kivitv.com/twin-falls/s...
www.kivitv.com/twin-falls/s...
Reposted by Tim Frasier
How bowhead whales live for centuries—and how we might borrow some of their biology to extend our healthy lifespan. Gift link to my new column: nyti.ms/4hyD9ry
October 29, 2025 at 4:33 PM
How bowhead whales live for centuries—and how we might borrow some of their biology to extend our healthy lifespan. Gift link to my new column: nyti.ms/4hyD9ry
Wow. Hadn't even thought about the implications of antivax ideas on pets and veterinarians...
Here's a response to anyone horrified about the number of people who will suffer and even die due to the aggressive ignorance of MAGA's antivax ideology: "Well, not just people." www.nytimes.com/2025/10/27/s...
Vaccine Skepticism Comes for Pet Owners, Too
www.nytimes.com
October 29, 2025 at 12:41 PM
Wow. Hadn't even thought about the implications of antivax ideas on pets and veterinarians...
Reposted by Tim Frasier
Do you also have a "To Read" folder that’s basically a black hole? 🕳️
My new blog post explores why that’s okay. And how to orbit the black hole instead of getting sucked in.
You’ll Never Keep Up with the Scientific Literature (and That’s Okay)
jenteottenburghs.wordpress.com/2025/10/28/y...
My new blog post explores why that’s okay. And how to orbit the black hole instead of getting sucked in.
You’ll Never Keep Up with the Scientific Literature (and That’s Okay)
jenteottenburghs.wordpress.com/2025/10/28/y...
October 28, 2025 at 7:43 PM
Do you also have a "To Read" folder that’s basically a black hole? 🕳️
My new blog post explores why that’s okay. And how to orbit the black hole instead of getting sucked in.
You’ll Never Keep Up with the Scientific Literature (and That’s Okay)
jenteottenburghs.wordpress.com/2025/10/28/y...
My new blog post explores why that’s okay. And how to orbit the black hole instead of getting sucked in.
You’ll Never Keep Up with the Scientific Literature (and That’s Okay)
jenteottenburghs.wordpress.com/2025/10/28/y...
Exciting opportunity to work on Marion Island!
mousefreemarion.org/vacancies/?f...
mousefreemarion.org/vacancies/?f...
Vacancies - Mouse-Free Marion
VACANCIES
Mouse-Free Marion Project Field Assistants
(April 2026 - May 2027 )
BirdLife South Africa, via the Mouse-Free Marion (MFM)
mousefreemarion.org
October 28, 2025 at 6:02 PM
Exciting opportunity to work on Marion Island!
mousefreemarion.org/vacancies/?f...
mousefreemarion.org/vacancies/?f...
Reposted by Tim Frasier
7 reasons to use Bayesian inference!
statmodeling.stat.columbia.edu/2025/10/11/7...
statmodeling.stat.columbia.edu/2025/10/11/7...
7 reasons to use Bayesian inference! | Statistical Modeling, Causal Inference, and Social Science
statmodeling.stat.columbia.edu
October 11, 2025 at 1:54 PM
7 reasons to use Bayesian inference!
statmodeling.stat.columbia.edu/2025/10/11/7...
statmodeling.stat.columbia.edu/2025/10/11/7...
Leaf blowers are one of the most effective tools I've seen for turning your problem into someone else's problem.
October 11, 2025 at 11:13 AM
Leaf blowers are one of the most effective tools I've seen for turning your problem into someone else's problem.
Reposted by Tim Frasier
Our paper (Brieuc Lehmann is the first author) is now online in Genetics.
academic.oup.com/genetics/adv...
academic.oup.com/genetics/adv...
On ARGs, pedigrees, and genetic relatedness matrices
Abstract. Genetic relatedness is a central concept in genetics, underpinning studies of population and quantitative genetics in human, animal, and plant se
academic.oup.com
October 9, 2025 at 1:47 AM
Our paper (Brieuc Lehmann is the first author) is now online in Genetics.
academic.oup.com/genetics/adv...
academic.oup.com/genetics/adv...
So sad to hear about the passing of Jane Goodall. She was a huge inspiration for me. I was lucky enough to see her give talk, and to meet here, many years ago. A huge loss.
Jane Goodall, ethologist and conservationist, has died. She was 91
October 1, 2025 at 6:46 PM
So sad to hear about the passing of Jane Goodall. She was a huge inspiration for me. I was lucky enough to see her give talk, and to meet here, many years ago. A huge loss.
Reposted by Tim Frasier
New story on the Avian Hybrids blog!
The hidden effects of genetic purging in Galápagos Mockingbirds
avianhybrids.wordpress.com/2025/10/01/t...
Based on the Molecular Ecology study by Jakub Vlček, Sebastian Espinoza-Ulloa and their colleagues | #ornithology
The hidden effects of genetic purging in Galápagos Mockingbirds
avianhybrids.wordpress.com/2025/10/01/t...
Based on the Molecular Ecology study by Jakub Vlček, Sebastian Espinoza-Ulloa and their colleagues | #ornithology
The hidden effects of genetic purging in Galápagos Mockingbirds
Exploring patterns of genetic load across island populations.
avianhybrids.wordpress.com
October 1, 2025 at 7:12 AM
New story on the Avian Hybrids blog!
The hidden effects of genetic purging in Galápagos Mockingbirds
avianhybrids.wordpress.com/2025/10/01/t...
Based on the Molecular Ecology study by Jakub Vlček, Sebastian Espinoza-Ulloa and their colleagues | #ornithology
The hidden effects of genetic purging in Galápagos Mockingbirds
avianhybrids.wordpress.com/2025/10/01/t...
Based on the Molecular Ecology study by Jakub Vlček, Sebastian Espinoza-Ulloa and their colleagues | #ornithology
Reposted by Tim Frasier
In 2020, O Gaggiotti, J Goudet and I showed that Qst-Fst comparison was uncalibrated with high population structure.
During her PhD with us, Isa do O developed LogAV: a method that accounts for any population structure while testing for local adaptation :
journals.plos.org/plosgenetics...
During her PhD with us, Isa do O developed LogAV: a method that accounts for any population structure while testing for local adaptation :
journals.plos.org/plosgenetics...
A method for identifying local adaptation in structured populations
Species occupy diverse, heterogeneous environments, which expose populations to spatially varied selective pressures. Populations in different environments can diverge due to local adaptation. However...
journals.plos.org
September 24, 2025 at 7:23 AM
In 2020, O Gaggiotti, J Goudet and I showed that Qst-Fst comparison was uncalibrated with high population structure.
During her PhD with us, Isa do O developed LogAV: a method that accounts for any population structure while testing for local adaptation :
journals.plos.org/plosgenetics...
During her PhD with us, Isa do O developed LogAV: a method that accounts for any population structure while testing for local adaptation :
journals.plos.org/plosgenetics...
Reposted by Tim Frasier
New article from @stefcraps.com!
Ecological apologies: reckoning with grief, guilt, and multispecies justice.
doi.org/10.1080/0964...
Ecological apologies: reckoning with grief, guilt, and multispecies justice.
doi.org/10.1080/0964...
September 24, 2025 at 6:27 AM
New article from @stefcraps.com!
Ecological apologies: reckoning with grief, guilt, and multispecies justice.
doi.org/10.1080/0964...
Ecological apologies: reckoning with grief, guilt, and multispecies justice.
doi.org/10.1080/0964...
Reposted by Tim Frasier
Week 2 mega preview with @patrickclaybon.bsky.social @jourdanrodrigue.bsky.social
- Buying more Jets stock
- Kyle Pitts SZN?
- The Titans defense: creditable
- Bo Nix trying stuff
- Puns. So many puns
🎧: landing.podtrac.com/nfldaily
📺: youtu.be/rxi0ko9dDp0?...
- Buying more Jets stock
- Kyle Pitts SZN?
- The Titans defense: creditable
- Bo Nix trying stuff
- Puns. So many puns
🎧: landing.podtrac.com/nfldaily
📺: youtu.be/rxi0ko9dDp0?...
September 11, 2025 at 2:52 PM
Week 2 mega preview with @patrickclaybon.bsky.social @jourdanrodrigue.bsky.social
- Buying more Jets stock
- Kyle Pitts SZN?
- The Titans defense: creditable
- Bo Nix trying stuff
- Puns. So many puns
🎧: landing.podtrac.com/nfldaily
📺: youtu.be/rxi0ko9dDp0?...
- Buying more Jets stock
- Kyle Pitts SZN?
- The Titans defense: creditable
- Bo Nix trying stuff
- Puns. So many puns
🎧: landing.podtrac.com/nfldaily
📺: youtu.be/rxi0ko9dDp0?...