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Uri Frank @thecocodium.bsky.social · Sep 4

Congrats Can!

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Uri Frank @thecocodium.bsky.social · Aug 30

Good to see this out—congrats Uli at al.

Reposted by Uri Frank

Alex de Mendoza @alexdemendoza.bsky.social · Aug 14

Chaetognaths have lost gene body methylation and shifted #5mC back to Transposable Elements. This reversion to the ancestral state is coupled with a simplification of DNMT3 architecture. We posit that trans-splicing might compensate.

It is an honour to have contributed to this 20y struggle ⛰️.

Ferdinand Marlétaz @ferdix.bsky.social · Aug 13

After nearly twenty years in the making, our attempt at understanding what makes the chaetognath phylum so unique has finally been published! www.nature.com/articles/s41...
with #LauraPiovani @dariagavr.bsky.social @alexdemendoza.bsky.social @chemamd.bsky.social and others /1

The genomic origin of the unique chaetognath body plan - Nature

Genomic, single-cell transcriptomic and epigenetic analyses show that chaetognaths, following extensive gene loss in the gnathiferan lineage, relied on newly evolved genes and lineage-specific tandem ...

www.nature.com

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Reposted by Uri Frank

International Society for Regenerative Biology @isrbio.bsky.social · Aug 18

We are excited to highlight our Rising Star Awardee, Dr. Can Aztekin @canaztekin.bsky.social whose work highlighting the importance of oxygen in regulating regeneration is inspiring. #Onetowatch

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Reposted by Uri Frank

International Society for Regenerative Biology @isrbio.bsky.social · Aug 18

Announcing this year's Life Time Achievement Award. The one and only amazing Professor Brigette Galliot. Our inspiration with both her research and her service.

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Reposted by Uri Frank

Matt Gibson @mgstowers.bsky.social · Aug 14

Cnidarian-Microbe Interactions
Fully-funded postdoctoral position is available in the Gibson Lab at the Stowers Institute to investigate any aspect of cnidarian-microbe interactions. Strong background in coral symbiosis or eukaryotic microbiology preferred.
Contact Matt Gibson: [email protected]

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Reposted by Uri Frank

Alex de Mendoza @alexdemendoza.bsky.social · Jul 28

Happy to see our latest work out in @molbioevol.bsky.social. We revisit the evolution of 5-methylcytosine across neglected eukaryotic supergroups, establishing an ancestral repressive role silencing genome invaders, both transposons and viral elements👾: academic.oup.com/mbe/advance-... 🧵 1/7

Repressive cytosine methylation is a marker of viral gene transfer across divergent eukaryotes

Abstract. Cytosine DNA methylation patterns vary widely across eukaryotes, with its ancestral roles being understood to have included both transposable ele

academic.oup.com

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Uri Frank @thecocodium.bsky.social · Jul 20

תנחומי

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Reposted by Uri Frank

Kaessmann Lab @kaessmannlab.bsky.social · Jul 16

Our study on a male-essential microRNA and the evolution of other dosage compensation mechanisms in birds is now out in Nature! www.nature.com/articles/s41...

A male-essential miRNA is key for avian sex chromosome dosage compensation - Nature

Birds have evolved a unique sex chromosome dosage compensation mechanism involving the male-biased microRNA (miR-2954), which is essential for male survival by regulating the expression of dosage-sens...

www.nature.com

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Uri Frank @thecocodium.bsky.social · Jul 17

Lovely work!! @kaessmannlab.bsky.social @danafrank.bsky.social

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Uri Frank @thecocodium.bsky.social · Jun 27

't was lovely to host @julianolab.bsky.social here @uniofgalway.bsky.social. Great presentation and lots of fun later on a pint with @jgahan.bsky.social @rmacgabhann.bsky.social @hrhorkan.bsky.social and friends.

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Uri Frank @thecocodium.bsky.social · Jun 20

I am looking for a new postdoc to join the lab. Interested in pluripotency, germ cells, and in investigating these in a genetically tractable cnidarian? Get in touch! We offer a long-term contract, excellent research environment, and a lovely city #Galway. www.urifranklab.org

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Uri Frank @thecocodium.bsky.social · Jun 14

Very nice work Grisha and David

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Reposted by Uri Frank

genikhovich.bsky.social @genikhovich.bsky.social · Jun 13

David’s @davidmoersdorf.bsky.social cool paper about the role of Chordin in BMP signaling in the sea anemone Nematostella is finally out www.science.org/doi/10.1126/...

Chordin-mediated BMP shuttling patterns the secondary body axis in a cnidarian

Chordin-mediated BMP shuttling is the candidate mechanism for generating bilateral symmetry in the cnidarian-bilaterian ancestor.

www.science.org

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Reposted by Uri Frank

Aide Macias-Muñoz @aidemm.bsky.social · Jun 4

Happy to share our genome paper now typeset. We sequenced and assembled the genome of Bougainvillia (jellyfish not the plant!) which has 28 eyes!
doi.org/10.1093/g3jo...

Bougainvillia jellyfish with 4 marginal bulbs

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Reposted by Uri Frank

Cnidarian developmental mechanisms group @clytia-vlfr.bsky.social · May 17

"Aboral cell types of Clytia and coral larvae have shared features and link taurine to the regulation of settlement" Kudos to Julia Ramon-Mateu and Anna Ferraioli @biodev-vlfr.bsky.social, and thanks to our collaborators for their coral larva expertise www.science.org/doi/10.1126/...

Aboral cell types of Clytia and coral larvae have shared features and link taurine to the regulation of settlement

Larvae of jellyfish and corals have specialized sensory cells with shared features potentially linked to settlement regulation.

www.science.org

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Reposted by Uri Frank

Karen Echeverri @karenecheverri.bsky.social · May 8

Delighted to see this work from my lab published today, where we identify a population of ETV-1 positive glutamatergic neurons that are activated in the brain in response to a distant injury.

www.nature.com/articles/s41...

Neuronal activation in the axolotl brain promotes tail regeneration - npj Regenerative Medicine

npj Regenerative Medicine - Neuronal activation in the axolotl brain promotes tail regeneration

www.nature.com

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Reposted by Uri Frank

Arnau Sebé-Pedrós @arnausebe.bsky.social · May 7

Check out our latest work on the evolution of animal genome regulation out today in @nature.com. Nicely summarized below by @ianakim.bsky.social.
www.nature.com/articles/s41...

This is a major output from our ERC-StG project Evocellmap @erc.europa.eu at @crg.eu

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Reposted by Uri Frank

Jordi Solana @jordisolana.bsky.social · May 7

Proud to present the peer-reviewed version of our Cell Type Allometry paper, out today in Science Advances!

www.science.org/doi/10.1126/...

Are animals of different sizes made of the same cell types?

Here’s an update of the main points and revision items

(with memes!)

Thread 👇🧵

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Uri Frank @thecocodium.bsky.social · Apr 30

Just back from visiting @viennabiocenter.bsky.social where I met with colleagues @ulrichtechnau.bsky.social @genikhovich.bsky.social @tessmarraiblelabs.bsky.social Oleg Simakov and many others. Lovely weather and great science.

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Reposted by Uri Frank

Nat Clarke @natclarke.bsky.social · Apr 18

‼️ Attention non-bilaterian enthusiasts ‼️

Join us for the non-bilaterian satellite symposium at PASEDB 2025 this July!

Come hear the latest in cnidarians, sponges, ctenophores & more!

Talks will be selected from abstracts. Contact me with questions. Register at the link below:

EvoDevo PanAm @evodevopanam.bsky.social · Apr 2

Our next meeting at Miami will have four satellite symposia: Spiralia, Arthropods, Fishes, and Non-bilaterian EvoDevo on July 22. Invited and selected talks from abstracts. Apply from here evodevo.wildapricot.org/event-6007396

The Pan American Society for Evolutionary Developmental Biology - 2025 Biennial Meeting of the Pan American Society for Evolutionary Developmental Biology

evodevo.wildapricot.org

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Reposted by Uri Frank

Arnau Sebé-Pedrós @arnausebe.bsky.social · Apr 10

Registrations are now open for the next @embo.org EvoChromo meeting in December.
meetings.embo.org/event/24-evo...

Join us in beautiful Costa Brava to discuss chromatin evolution!

Co-organized with @tobiaswarnecke.bsky.social @sandraduharcourt.bsky.social @levine-lab.bsky.social and Nick Irwin

EvoChromo: Evolutionary approaches to research in chromatin

Chromatin is the complex of DNA, RNA and protein that is found making up the chromosomes in eukaryotic cells. Chromatin is essential for proper genome function and is involved in chromosome segregati…

meetings.embo.org

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Reposted by Uri Frank

Development @dev-journal.bsky.social · Apr 8

In this Review, @bernasozen.bsky.social, Patrick Tam & Martin Pera summarize how recent studies of embryo models have advanced our understanding of cell state transitions of the pluripotent human epiblast and highlights some key remaining questions:
doi.org/10.1242/dev....

Figure 2 Overview of cell state transitions in hPSCs in 2D and 3D embryo models. Embryo illustrations on the left represent the in vivo developmental stages corresponding to the three pluripotency states: naive (yellow), formative/intermediate (light green) and primed (dark green). On the right, the lineages they have the potential to give rise to in stem cell-based embryo models are illustrated. The generation of primordial germ cells (PGCs) from amnion remains to be determined. EXM, extra-embryonic mesoderm; PGCs, primordial germ cells.

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Uri Frank @thecocodium.bsky.social · Apr 8

James' lab is is doing fantastic work in chromatin evodevo.

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Reposted by Uri Frank

EpiCypher @epicypher.bsky.social · Mar 24

🧬🧪Exciting chromatin research conference hosted by @aicc-ireland.bsky.social in May! The deadline for poster/talk abstracts is April 28, see details in the post below.

All-Ireland Chromatin Consortium @aicc-ireland.bsky.social · Mar 24

We are very excited to launch the registration for our 2025 symposium on 'Chromatin, Epigenetics and Transcription' today!

Join us at @tcddublin.bsky.social on May 28th for this event featuring keynote, new PI and PhD/postdoc talks and posters!

allirelandchromatinconsortium.ie/annual-meeti...

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