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Reposted by Vince Luca, PhD

Daniel V. Oliveira @danielvoliveira.bsky.social · 2d

If you’re around at the #NotchMeetingXIII poster session today, come by to check out Poster #9! 🧬✨
@anna_frontino will be there presenting our shared work on how Jagged1 variants shape liver vascular and biliary development.
Stop by to say hi and chat Notch!

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Reposted by Vince Luca, PhD

Denis Wirtz @deniswirtz.bsky.social · 3d

CAR T therapy has seen great effectiveness in liquid tumors, but little in solid tumors (e.g. ovarian cancer).

Here we developed hyper-migratory CAR TV cells to infiltrate en masse ovarian tumors. (Left: control CAR T cells; right CAR TV cells).

Read this here: www.biorxiv.org/content/10.1...

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Vince Luca, PhD @thelucalab.bsky.social · 8d

Good luck - ridiculous situation!

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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 21d

I've been watching as NIGMS works their tails off to get R35 awards out the door before the end of the FY on 30 Sept. They all look great but this one really grabbed my attention.

It's about long "noncoding" (lnc) RNA's. Only, this one *does* encode peptides…

reporter.nih.gov/project-deta...

RePORT ⟩ RePORTER

reporter.nih.gov

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Reposted by Vince Luca, PhD

Antoni Wrobel @agwrobel.bsky.social · Sep 8

Dear scientific community,

I am looking for two postdoctoral structural biologists to join my group at the Department of Biochemistry, University of Oxford.

my.corehr.com/pls/uoxrecru...

my.corehr.com/pls/uoxrecru...

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Vince Luca, PhD @thelucalab.bsky.social · Sep 4

This makes me feel old/nostalgic/proud all at the same time. What a great crew!

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Research Professional News @resprofnews.bsky.social · Aug 26

University efficiency drives may have opposite effect, study finds.

The administrative burden in Australian universities is most keenly felt by teaching and research staff, according to a study from the University of Melbourne’s faculty of education.
www.researchprofessionalnews.com/rr-news-aust...

University efficiency drives may have opposite effect, study finds - Research Professional News

Teaching and research staff say reforms mean more red tape for them, Australian survey reports

www.researchprofessionalnews.com

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Vince Luca, PhD @thelucalab.bsky.social · Aug 27

I should clarify. We’ve made minibinders to 5-6 different targets now. We don’t get 100% success rate for every binder, but we’ve gotten at least one hit out of 10-20 candidates screened (in line with the rates they indicate in the paper).

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Vince Luca, PhD @thelucalab.bsky.social · Aug 27

Bindcraft is awesome! If you haven’t already seen the preprint check out the final pub here. We’ve had nearly 100% success using it for the targets we’ve attempted.

Martin Pacesa @martinpacesa.bsky.social · Aug 27

Exciting to see our protein binder design pipeline BindCraft published in its final form in @Nature ! This has been an amazing collaborative effort with Lennart, Christian, @sokrypton.org, Bruno and many other amazing lab members and collaborators.

www.nature.com/articles/s41...

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Reposted by Vince Luca, PhD

Martin Pacesa @martinpacesa.bsky.social · Aug 27

Exciting to see our protein binder design pipeline BindCraft published in its final form in @Nature ! This has been an amazing collaborative effort with Lennart, Christian, @sokrypton.org, Bruno and many other amazing lab members and collaborators.

www.nature.com/articles/s41...

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Vince Luca, PhD @thelucalab.bsky.social · Jul 23

I would guess it’s borne out of insecurity - they may not want the burden/responsibility for making final decisions. I think the same issue is pervasive in journal editors when reviewers are conflicted.

Vince Luca, PhD @thelucalab.bsky.social · Jul 9

Did they really not list the cap in the article!?

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Vince Luca, PhD @thelucalab.bsky.social · Jul 1

Congrats!!! 😎

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derek guy @dieworkwear.bsky.social · May 23

Am I crazy or did we just have a convo about how we can't fund cancer research?

Senator Marsha Blackburn tweets: "We're going to build a big, beautiful Golden Dome."

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Senator Bernie Sanders @sanders.senate.gov · May 16

Donald Trump cut funding for cancer research by 31% in the first three months of his term.

This is an attack on every American family who has loved someone with cancer.

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Tom Ellis @proftomellis.bsky.social · May 2

My dept in London at Imperial (Bioengineering) is recruiting a group leader at Professor level 🧑‍🎓 Please RT. It's a great place with world-class expertise in all sorts of biomedical & biological engineering topics like synthetic biology. It's also not in the USA. www.imperial.ac.uk/jobs/search-...

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Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · Apr 30

"I would not have dared to dream that metastatic melanoma would become a treatable disease in my lifetime. Yet here we are today, with 43% of people diagnosed with metastatic melanoma living 10 years or more, due to treatments that we broadly refer to as cancer immunotherapy." Barry P. Sleckman, UAB

Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · Apr 12

The Senate Committee on Appropriations is holding a hearing on Biomedical Research: Keeping America’s Edge in Innovation on April 30 at 10:30am ET, chaired by Senator Susan Collins 🧪

www.appropriations.senate.gov/hearings/bio...

Biomedical Research: Keeping America’s Edge in Innovation | United States Senate Committee on Appropriations

United States Senate Committee on Appropriations

www.appropriations.senate.gov

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Reposted by Vince Luca, PhD

Flora Rutaganira @frutag33.bsky.social · Apr 21

Hello Community!
Are you a postdoc/grad student preparing to launch a faculty search? Do you have a track record of excellence in research, leadership, mentorship & community engagement? Apply to the 2025 Next Generation Faculty Symposium: www.berkeleystanfordnextgensymposium.com! Pls repost! (1/3)

Flyer for the 2025 Next Generation Faculty Symposium (including QR code in top right corner). This symposium highlights the work of exceptional early-career scientists in the broad field of quantitative biological and biomedical sciences, with a track record of excellence in research, leadership, mentorship, and community engagement. These early career scientists are preparing to launch a faculty search. Applications are due May 30th, 2025.

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Carolyn Bertozzi @carolynbertozzi.bskyverified.social · Apr 25

Huge opportunity for postdocs gearing up for an academic job search, hosted by @stanford-chemh.bsky.social @berkeleymcb.bsky.social and UCSF!

Flora Rutaganira @frutag33.bsky.social · Apr 21

Hello Community!
Are you a postdoc/grad student preparing to launch a faculty search? Do you have a track record of excellence in research, leadership, mentorship & community engagement? Apply to the 2025 Next Generation Faculty Symposium: www.berkeleystanfordnextgensymposium.com! Pls repost! (1/3)

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Daniel Convissor @danielconvissor.bsky.social · Apr 19

Actually, flip the headline. It's really "How the Federal Government Became so Dependent on Universities."

These competitively awarded, peer reviewed research grants produce tremendous returns on investment. New tech, health, science that benefit all people & businesses in the USA & world.

Chris Bail @chrisbail.bsky.social · Apr 19

www.nytimes.com/2025/04/18/u...

How Universities Became So Dependent on the Federal Government

For decades, universities got billions in federal dollars for research. The relationship was mutually beneficial, until President Trump decided it wasn’t.

www.nytimes.com

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Reposted by Vince Luca, PhD

Xantha Karp @xanthakarp.bsky.social · Apr 11

Congratulations to Iva Greenwald and Gary Struhl for the Gairdner Award for their work on Notch!! It’s so lovely to have some good news in these difficult times. zuckermaninstitute.columbia.edu/columbia-gai...

Columbia Scientists Win International Award for Fundamental Research that Advances Understanding of Biology and Disease

zuckermaninstitute.columbia.edu

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Vince Luca, PhD @thelucalab.bsky.social · Apr 2

My MIRA went to Council in September and was awarded on 02/01/2025. A colleague had a similar timeline for theirs, so it seems like some are getting through. Ours were both renewals (not sure that matters).

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Daniel Gorelick @danielgorelick.bsky.social · Mar 25

New preprint, very proud of this one www.biorxiv.org/content/10.1...

Fast & Fair peer review: a pilot study demonstrating feasibility of rapid, high-quality peer review in a biology journal

Traditional peer review is slow, often delayed by the time-consuming process of identifying reviewers and lengthy review turnaround times. This study tests the feasibility of the Fast & Fair peer revi...

www.biorxiv.org

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Chrystal Starbird @drstarbird.bsky.social · Mar 24

There is still time to apply for this funded postdoc position! 👇🏾Applicants must apply using the link in the original post below to be considered. Please apply if interested!

Chrystal Starbird @drstarbird.bsky.social · Mar 18

Our lab is excited to hire a postdoctoral researcher to study the mechanisms that viruses use to ‘hijack’ TAM receptors in viral spread. We are looking for someone who is excited to learn new techniques and work in a highly collaborative team! Please share!

unc.peopleadmin.com/postings/298...

Schematic of potential complexes that form between TAM receptors and apoptosis cells or viruses at the cell surface

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Vince Luca, PhD @thelucalab.bsky.social · Mar 15

Can you clarify this a bit? I think most outsiders (self included) don’t understand the implications for NIH either way. I get the argument that dems should use the shutdown for leverage, but how specifically does the NIH benefit?

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