tianyang22.bsky.social
Tianyang Liu
@tianyang22.bsky.social
34 followers 73 following 3 posts
Postdoc @Moores Lab in London. Interested in cytoskeleton and cryoEM🐍🐍🐍
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tianyang22.bsky.social
Tianyang Liu @tianyang22.bsky.social · 22d
Our paper on Arp2/3-mediated bidirectional actin assembly is out @natsmb.nature.com 🚀 After great reviews & community feedback, this version includes new insights beyond the preprint:) Huge thanks to all co-authors!!! @drmichaelway.bsky.social @romet-jegou-lab.bsky.social @carolynmoores1.bsky.social
drmichaelway.bsky.social
Michael Way @drmichaelway.bsky.social · 23d
And now for something completely different @tianyang22.bsky.social & #YanCao uncover of how SPIN90 dimers activate Arp2/3 to nucleate bidirectional linear actin filaments. Great collaboration with @romet-jegou-lab.bsky.social & @carolynmoores1.bsky.social #Cryo-EM #Arp2/3 rdcu.be/eGoH4
Arp2/3-mediated bidirectional actin assembly by SPIN90 dimers
Nature Structural & Molecular Biology - Liu et al. show that SPIN90 dimerizes and binds two Arp2/3 complexes to nucleate two bidirectional actin filaments and the dimerization domain is...
rdcu.be
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Reposted by Tianyang Liu
ruizhangmt.bsky.social
Rui Zhang @ruizhangmt.bsky.social · Mar 13
Another wonderful collaboration with @alanbrownhms.bsky.social lab 👇
Zhang lab (co-first author @qingweiniu.bsky.social) contribute the doublet structure from Crithidia fasciculata, a model organism that infects mosquitoes.
matthdoran.bsky.social
Matt Doran @matthdoran.bsky.social · Mar 13
I am super excited to share our latest work on the structures of doublet microtubules from trypanosomatid parasites, the causative agents of leishmaniasis, Chagas disease, and African sleeping sickness. tinyurl.com/48sh3xn5
Evolutionary adaptations of doublet microtubules in trypanosomatid parasites
The movement and pathogenicity of trypanosomatid species, the causative agents of trypanosomiasis and leishmaniasis, are dependent on a flagellum that contains an axoneme of dynein-bound doublet micro...
tinyurl.com
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Reposted by Tianyang Liu
thibautbrunet.bsky.social
Thibaut Brunet @thibautbrunet.bsky.social · Feb 17
Excited to announce the 10th "Choanoflagellates & Friends Workshop" over May 20-22 in our own Institut Pasteur in Paris: 2025choanocon.wordpress.com Registrations open til March 15, abstract til March 5. Pre-conference event for students/postdocs on 19/05. Plenty of slots for selected talks/posters!
Choanoflagellates and other holozoan relatives of animals arranged in the shape of the Eiffel tower. Drawing by Eva Pillai.
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tianyang22.bsky.social
Tianyang Liu @tianyang22.bsky.social · Feb 4
Thank you:)
tianyang22.bsky.social
Tianyang Liu @tianyang22.bsky.social · Jan 31
Working on actin cytoskeleton and Arp2/3 complex? Check out our latest work～https://www.biorxiv.org/content/10.1101/2025.01.31.635869v1
In this work, we found SPIN90 forms a dimer, facilitating bidirectional actin filament nucleation by activating two Arp2/3 complex #Cryo-EM #Actin #Arp2/3
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