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tokiosunshine.bsky.social
@tokiosunshine.bsky.social
Reposted
Today's Paper of the Day is:

Practical approach to hyponatraemia and hypernatraemia in critically ill patients

criticalcarereviews.com/latest-evide...

Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
May 30, 2025 at 7:25 AM
Reposted
Useful references:
Alrashed MA, et al. Journal of Pharmacy Practice 2022; 36(4): 756-60. doi: 10.1177/08971900211061937
Spencer S, et al. Hospital Pharmacy 2018; 53(3): 157-69. doi: 10.1177/0018578718760257
May 17, 2025 at 2:55 PM
Reposted
EMCrit 394 is Part 2 of Inotropes with Trina - we discuss specific scenarios:
- Cardiogenic Shock
- Right Heart Failure/Massive PE
- Sepsis Cardiomyopathy
[#FOAMed for a bit]
emcrit.org/394
February 8, 2025 at 12:06 AM
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EMCrit Ghali Grills 003 - Further Disambiguating "PEA"
We dive DEEP into PEA, when to stop CPR, how to know when you have adequate perfusion after ROSC, and a bunch more!!!
[#FOAMed] @EM_RESUS
emcrit.org/esk1
EMCrit Ghali Grills 003 - Further Disambiguating "PEA"
We dive DEEP into PEA, when to stop CPR, how to know when you have adequate perfusion after ROSC, and a bunch more!!!
emcrit.org
May 10, 2025 at 10:18 PM
Reposted
Among >90YO patients who had a cardiac arrest in ICU, this study found an in-hospital mortality of 100% (25/25)

Big difference between out-of-hospital arrest vs. in-ICU arrest

In-ICU arrest reflects failure of aggressive ICU-level medical treatments; this usually implies a poor prognosis. #EMIMCC
January 4, 2025 at 3:20 PM
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AVP
December 29, 2024 at 4:03 AM
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Do you have a protocol at your shop to guide management of cardiogenic shock patients? Consider taking a good look at this one. 🎩 tip to the authors.

eddyjoemd.com/foamed/
December 26, 2024 at 10:16 AM
Reposted
What if love was as certain an aspect of the human condition as death and taxes?

In this Editor's Choice, Tasnime Osama and @rich-hurley.bsky.social discuss how these three forces shape our health, lives, and world
#ChristmasBMJ
www.bmj.com/content/387/...
December 23, 2024 at 11:54 AM
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Treating patients, not P values.
Recently, NEJM published 2 RCTs of LVFX to prevent MDR-TB, and a meta-analysis pooling them was published in NEJM Evidence. This editorial explains how to interpret the MA, which integrated "negative" RCTs to become "positive."
evidence.nejm.org/doi/full/10....
Treating Patients, Not P Values
To the dismay of many statisticians, clinicians are taught to convert continuous results into a binary value to facilitate decision-making. A person with a hemoglobin A1c level of 6.5% or higher ha...
evidence.nejm.org
December 20, 2024 at 3:24 AM
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1/16
🤔Why does carcinoid syndrome affect the right heart valves more often than the left heart valves?

The difference is striking.

Let's have a look.
November 16, 2024 at 8:04 PM
Reposted
Today's Paper of the Day is n-acetylcysteine in non-acetaminophen acute liver failure

https://criticalcarereviews.com/latest-evidence/paper-of-the-day

Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2024
December 15, 2024 at 12:18 PM
Reposted
Caught btw rock & hard place. Despite having ↑↑internal validity, RCTs often lack generalizability. They're so controlled that they can’t be applied to real🌎, where things 🚫perfectly fit. Studies that capture real🌎 face ↓↓internal validity d/t ↓controls &↑↑confounders #medsky #pharmsky #MedEd #EMsky
Fresh blog: the ADAPT and SCREEN trials are full of sound & fury, signifying little

🤷‍♂️ Sepsis screens & procal-based ABX duration are highly context-dependent interventions. Effects will vary depending on baseline usual care.

🤷‍♂️ They lack generalizability.

emcrit.org/pulmcrit/ada... #EMIMCC
PulmCrit: ADAPT and SCREEN trials are full of sound and fury, signifying little
I think ICU docs may have developed a bit of an RCT problem; not an addiction, but perhaps a dependency. It all started off fine at first. RCTs are the
emcrit.org
December 14, 2024 at 1:18 AM
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Sepsis and Septic Shock from the legend @theplaguemd #FOAMed #FOAMcc #sepsis @sepsisUK
November 22, 2024 at 5:53 AM
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ICU Hemodynamics:

Refresher from Michael Pinsky's lecture:
December 8, 2024 at 5:05 AM
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You've heard of FOMO: the Fear of Missing Out. But have you heard about FOMAR? The Fear of Missing a Reference? Just one more search. One more scan of the literature. What if I miss something? #PhDchat #PhDforum #ECRchat
December 10, 2024 at 12:00 PM
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Editorial: High-flow oxygen can serve as a safe bridge therapy while the underlying cause of acute respiratory failure is determined and the most appropriate respiratory support is ultimately implemented.

#CCRdownunder

ja.ma/4f8BlTC
December 11, 2024 at 12:40 AM
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Editorial: While the SCREEN trial shows promise in using EHR-based sepsis alerts to reduce mortality, further studies are needed to understand the effectiveness of these alerts.

#CCRdownunder @criticalcarereviews.com

ja.ma/4g9yyuK
December 11, 2024 at 4:55 AM
ICU Physiology Secrets - Return to Basics Edition:

If you are placing Swan-Ganz (SG) catheters or you like reading/interpreting their waveforms, this is for you:

You walk in a patient’s room exactly when your fellow intensivist tries to “wedge” a newly placed SG catheter.
December 11, 2024 at 9:30 AM
Reposted
skytorial: my zentensivist urosepsis secrets

this is a super common ICU admission & usually pretty gratifying because patients turn around fast.

there are really just four main things you need to do... 🧵
a cartoon baby is sitting in a chair with the words `` it 's a secret '' written on it .
ALT: a cartoon baby is sitting in a chair with the words `` it 's a secret '' written on it .
media.tenor.com
December 5, 2024 at 6:53 PM
Reposted
Among critically ill adults who received invasive mechanical ventilation for more than 24 hrs, screening frequency (once-daily vs more frequent screening) & SBT technique (pressure-supported vs T-piece SBT) did not change the time to successful extubation.

https://ja.ma/3OEeAMu
December 7, 2024 at 1:00 PM