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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 4m

Ubuntu or Mint if you have never used Linux before

Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 17h

I didn't have an option at work. I just but Ubuntu in a home win10 device

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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 19h

Ilustrating the consequences of premature closure in medical diagnosis

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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 20h

Our IT has a hard policy of not reimaging hard disks of anything that is over 5 years old, so that was not an option with many of the devices. Other devices such as mine died before the update

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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 21h

I feel the pain - had to replace over 20 functional devices. Hopefully the anonymous ebay buyer will put Linux and squeeze another 10 years out of them

Prof. Ian Walker @ianwalker.bsky.social · 1d

Nobody needs Windows 11, and I shudder to think how much e-waste this pointless "upgrade" will generate

Windows 10 EOL could generate £1.8B of e-waste in UK alone • The Register www.theregister.com/2025/10/08/w...

Windows 10 EOL could generate £1.8B of e-waste in UK alone

: Recyclers reckon millions of obsolete PCs could yield a small fortune in precious metals

www.theregister.com

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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 22h

Perhaps the system should ask the question why Irish docs want to get out of Ireland in the first place? We had a few Irish med students doing away rotations with us and none of them planned to stay : even if the US plan didn't pan out, they had fall back plans for Canada, NZ and Australia

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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 22h

sort out patterns, any narrative is possible. In other words, grifters are gonna grift, so comment on their work using pretest probability alone, i.e., just call it BS. And please DO NOT give unserious take, serious commentary.

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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 22h

At a technical level, the analysis of time series of disease incidence data demonstrates all the pitfalls associated with APC (Age-Period-Cohort) models. Since the APC math can not constrain interpretation and most datasets don't contain subject level mechanistic data to ...

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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 22h

Technically the analysis of incidence data demonstrate all the pitfalls associated with APC models. Since the APC math cannot constrain interpretation, any narrative is possible. In other words, grifters are gonna grift so comment on their work using pretest probability alone ie just call it BS.

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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 22h

BTW be prepared for the cancer-in-the-young to emerge as a frequent theme going forward in time. In fact it already has in the form of "turbo cancers" by the anti-vax movement.

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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 23h

I didnt like @fperrywilson.bsky.social editorial ; not because of the content that was excellent but because it could have been drastically shorter : url to the paper being commented, followed by 3 characters, ie ➡️BS.

Unserious articles don't deserve serious commentary.

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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 1d

The slopbots didn't fail to code a sys admin utility in Perl tonight. Looking at the stolen code I'd say the original was written with Perl v5.8 but used the PBP book (released in 2005) conventions for documentation. So it was pieced together from stuff written between 2005-2009.

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Reposted by Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc

Morgan @mackenmo.bsky.social · 1d

AlphaKeto here; maybe obvious, but for students reading I would emphasize the importance of purposeful curiosity-driven memorization to facilitate conceptual application. Memorizing facts w/ rigid thinking DOES trap you, while doing so expecting your understanding of them to deepen & change is key.

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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 1d

We're they kings in no need of last name?

Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 1d

Who are the other 2?

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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 1d

Screenshot

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Reposted by Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc

Quijote1 @quijote1.bsky.social · 1d

data, prototyping etc. It doesn't matter if you in the end forget and use prof literature instead. These skills are there to stay.

I see it in my students: the ones who tend to put in the effort to memorize are better at *understanding* and sorting new information that they don't have to memorize.

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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 1d

A couple of technical comments on my approach . It has served me well in medicine, statistics, technology hobbies

mastodon.social/@ChristosArg...

Christos Argyropoulos MD PhD (@[email protected])

@[email protected] paper notes. My mentee @AlphaKeto asked me if I kept my notes from med school and the answer is yes. I use them for cross reference. Same things apply to my programming books whic...

mastodon.social

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Reposted by Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc

Quijote1 @quijote1.bsky.social · 1d

Unpopular opinion: I think memorization fosters transferable skills in *any* job, not just medicine: patience, resilience during inevitable failure, focus for long periods of time, resistance to distractors, task maintenance in working memory, sorting, extracting relevant information, organizing

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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 1d

I think I may follow the lead of others who have reverted to mid-2010s social media activity when many/most of us would blog elsewhere and then use social media such as Twitter as distribution channels. For those who don't want to bother with their own blogs , #LinkedIn is decent

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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 1d

data from #EMPAKIDNEY show that one can deliver material benefits among those who don't tolerate the older therapies.
Perhaps I am missing something, but while I see the immense value of programs to deliver #4pillar high value care, I don't see the value to partner with a #VBC.

Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 1d

electronic health record and appointment reminders to track and assist with adherence. Just two of the now generic #4pillars (angiotensin and #flozin) pack more punch than what the #VBC ever promised to deliver. In the angiotensin blocker, intolerant patients ...

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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 1d

If a physician practice could get somehow get their Medicare patients on #angiotensin blockade #flozin #nsMRA and #glp1 (e.g. secondary insurance or coinsurance) why would they partner with a #VBC and share cost savings from the drugs? Just write a script & use the ...

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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 1d

underutilized (proven to be wrong by the #UPMC trial that demonstrated that the perceived underutilization was just the ceiling of these therapies). Since most #VBC worked with Medicare Part B (which does not cover drugs), they can not even pay for the #4pillars.

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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 1d

Can anyone articulate the value of the value based care in chronic kidney disease in the era of the #4pillars? Trad #VBC was based on the premise that generic angiotensin blockade was sufficient (false) and ....

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