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Anestis Tsakiridis @tsakiridis.bsky.social · 2d

I am co-organising a @cclguk.bsky.social @dmmjournal.bsky.social symposium on the developmental origins of paediatric cancers at the @crick.ac.uk on 8/6/2026. Great speaker line up, affordable registration and available slots for short talks-spread the word! www.cclg.org.uk/information-...

Developmental origins of paediatric cancer symposium

A one-day event showcasing the latest cutting-edge research on the modelling, biology and treatment of paediatric cancers in the context of their developmental origins.

www.cclg.org.uk

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Reposted by Anestis Tsakiridis

Mikhail Spivakov @mspivakov.bsky.social · 5d

Many enhancers that drive tissue-specific gene expression are already connected to gene promoters in human pluripotent cells.

In a new preprint, we share some clues about when, how, and why this happens!

www.biorxiv.org/content/10.1...

Poising and connectivity of emergent human developmental enhancers in the transition from naive to primed pluripotency

In primed human pluripotent stem cells (hPSCs) resembling post-implantation epiblast, numerous lineage-specific enhancers assume the poised chromatin state, co-marked by H3K4me1 and Polycomb-associate...

www.biorxiv.org

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Reposted by Anestis Tsakiridis

Sara Wickstrom @sarawickstrom.bsky.social · 9d

How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇

Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells - Nature Cell Biology

McCreery, Stubb et al. show that mechano-osmotic changes in the nucleus induce general transcriptional repression and prime chromatin for cell fate transitions by relieving repression of specific differentiation genes.

www.nature.com

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Reposted by Anestis Tsakiridis

bioRxivpreprint @biorxivpreprint.bsky.social · 13d

Neuroblastoma-associated ALK variants have distinct cellular and biochemical activities https://www.biorxiv.org/content/10.1101/2025.09.25.677354v1

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Reposted by Anestis Tsakiridis

Alexis Barr @alexisbarr.bsky.social · 20d

@mariasecrier.bsky.social & I are looking for an enthusiastic & excellent data scientist for a 4-year postdoc to understand cell cycle dysregulation in cancer.

Deadline 15th October. Get in touch if you have any questions.

Please repost!

More details:
www.imperial.ac.uk/jobs/search-...

Description

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

www.imperial.ac.uk

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Reposted by Anestis Tsakiridis

Yaser Atlasi @yatlasi.bsky.social · 21d

We have an exciting, fully funded PhD studentship (UK and ROI) to investigate mechanisms of epigenetic regulation in drug resistant B-cell lymphoma.

We are looking for a highly motivated, driven candidate to join our team.

eur02.safelinks.protection.outlook.com?url=https%3A...

Targeting USP7-PRC1 axis as a novel therapeutic approach in drug resistant Diffuse Large B-Cell Lymphoma at Queen’s University Belfast on FindAPhD.com

PhD Project - Targeting USP7-PRC1 axis as a novel therapeutic approach in drug resistant Diffuse Large B-Cell Lymphoma at Queen’s University Belfast, listed on FindAPhD.com

eur02.safelinks.protection.outlook.com

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Reposted by Anestis Tsakiridis

Elaine Emmerson @doctoremmerson.bsky.social · 25d

I am advertising for a #postdoc for a 3 year BBSRC-funded project exploring the role of macrophages in salivary gland development. The successful candidate will be based at @edinuni-irr.bsky.social at @uni-of-edinburgh.bsky.social. Closing date: 9th Oct. elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

Postdoctoral Research Fellow

An exciting opportunity has arisen to join the Emmerson lab within the Institute for Regeneration and Repair at the University of Edinburgh. This three year, BBSRC-funded postdoctoral research associa...

elxw.fa.em3.oraclecloud.com

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Anestis Tsakiridis @tsakiridis.bsky.social · 27d

A 6-month postdoc position is currently available in our group. The project involves the use of hPSC-based models to dissect the links between chromosomal copy number alterations, DNA damage and tumour initiation-please spread the word-closing date=29th Sept: www.jobs.ac.uk/job/DON353/r...

Research Associate (Stem Cell/Cancer Biology)

jobsite.sheffield.ac.uk

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Reposted by Anestis Tsakiridis

Matt Towers @matt-towers.bsky.social · 29d

I'm a bit late to the party over here. I'll be advertising a BBSRC-funded postdoc position soon. So if anyone wants to solve some outstanding questions in limb development - please get in touch. We have a variety of models and approaches (everything from stem cells to sharks). towerslab.weebly.com

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Anestis Tsakiridis @tsakiridis.bsky.social · Aug 19

Really nice work by @fredwck.bsky.social and the groups of Val Wilson and Ian Chambers (including a small contribution from me from my Edinburgh postdoc years) showing how pluripotency factors can temporally orchestrate both pluripotency and it extinction: www.embopress.org/doi/full/10....

NANOG is repurposed after implantation to repress Sox2 and begin pluripotency extinction | The EMBO Journal

imageimageSOX2 and NANOG are core transcription factors governing pre-implantation pluripotency in the developing embryo. Here, extensive in vivo imaging and genetic analysis uncovers a novel post-imp...

www.embopress.org

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Reposted by Anestis Tsakiridis

Karen J Liu @karenjliu.bsky.social · Aug 5

Dev biologists! 3-yr postdoc position at King's, collaboration with Trizzino lab @marcotrizzino.bsky.social modelling CHD3 neural crest. We are looking for postdocs with mad embryology skills @the-node.bsky.social #developmental @ccrb27.bsky.social

thenode.biologists.com/jobs/postdoc...

Postdoctoral Research Associate: Modelling Neural Crest Anomalies (mouse/human) - the Node

The Liu lab is looking for a postdoc with a love of embryos and developmental biology! This post is part of an MRC-funded collaboration between Karen Liu’s lab at King’s College London and Marco Trizz...

thenode.biologists.com

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Reposted by Anestis Tsakiridis

Vicki Metzis @vmetzis.bsky.social · Aug 1

Application deadline for up to 5 @mrc-lms.bsky.social postdoc positions in developmental epigenetics closes soon - don’t miss out! Positions across both experimental and computational projects. Come and join our fantastic team science community!

Vicki Metzis @vmetzis.bsky.social · Jul 14

Interested in developmental epigenetics? So are we! Apply now to join us for your postdoc!

Multiple positions across multiple groups @mrc-lms.bsky.social

Projects spanning germline demethylation, gene regulation, genome architecture in development & disease 👇👇

lms.mrc.ac.uk/work/vacanci...

MRC Postdoctoral Research Scientists x 5 - MRC Laboratory of Medical Sciences

Applications are now open for up to five postdoctoral positions in the area of developmental epigenetics.

lms.mrc.ac.uk

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Reposted by Anestis Tsakiridis

Mill_lab @cilialab.bsky.social · Jul 7

📣 Cilia Lab is growing 📣 - we have 2️⃣ open positions at @uoe-igc.bsky.social @edinburgh-uni.bsky.social for talented and motivated researchers interested in disease modelling & genetic therapies which target #RareRespiratoryDiseases at their root cause. 🧪🧪#ciliopathies #PrimaryCiliaryDyskinesia 1/4

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Reposted by Anestis Tsakiridis

Candice Fung @candicefung.bsky.social · Jul 9

Ecstatic to share our paper on nutrient signaling in the #EntericNervousSystem published in Nature! 🧪

We explored how neurons in the gut respond to basic nutrients that we typically ingest and tested whether they can distinguish between different nutrients 🔬

Check it out 👉 tinyurl.com/3vc756dv

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Reposted by Anestis Tsakiridis

Anzy Miller @anzymiller.bsky.social · Jul 3

Looking foward to the Northern(ish) Developmental Biology Meeting 2025 next week @sheffielduni.bsky.social! Thanks to the organisers @shaneherbert.bsky.social Raman Das @tsakiridis.bsky.social @kyracampbelllab.bsky.social

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Anestis Tsakiridis @tsakiridis.bsky.social · Jul 1

ENS aficionados, mark your calendars: the next symposium on enteric nervous system development, function and repair, will be held at KU Leuven from 7–10 April 2026. Excellent line up of speakers and the website is now live so for more details check: ens-leuven2026.eu ‪

ens-leuven2026.eu

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Reposted by Anestis Tsakiridis

Vicki Metzis @vmetzis.bsky.social · Jun 27

Paper alert! I am really pleased to share the final version of the work led by Irène Amblard in the team on a regulatory switch controlling Cdx2 expression during posterior body development! #regulatorylogic #devbio @mrc-lms.bsky.social @imperialmed.bsky.social

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Anestis Tsakiridis @tsakiridis.bsky.social · Jun 27

Congrats Vicki!

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Development, Regeneration and Neurophysiology @drn-sheffield.bsky.social · Jun 25

Today’s speaker in our DRN external seminar series is Dr Sissy Wamaitha from the University of California, Los Angeles (UCLA)

Sponsored by the Physiological Society @physoc.bsky.social

Host: Stan Strawbridge
@stanleystrawbridge.bsky.social

All welcome!

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Reposted by Anestis Tsakiridis

Stanley E. Strawbridge @stanleystrawbridge.bsky.social · Jun 24

🚨 New paper out in Development! 🚨

We show that donor embryonic stem cells (ESCs) reshape the developing mouse embryo, not just by what they signal, but where they push.

📄 doi.org/10.1242/dev....

[1/8]

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Reposted by Anestis Tsakiridis

Stanley E. Strawbridge @stanleystrawbridge.bsky.social · Jun 4

1/10🧵 New preprint! 🚀
We built a resource of 20 clonal human naïve pluripotent stem cell lines from 10 blastocysts. Explore embryo-to-embryo and clone-to-clone variation in one place.
👉doi.org/10.1101/2025.06.02.657331

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Reposted by Anestis Tsakiridis

FlyBase @flybase.bsky.social · Jun 3

We currently have a call for support that has gone out to European labs, to support FlyBase-UK. We are asking our colleagues from labs in the US and other countries to wait for a similar call to them that will go out in the near future, to support the US sites. We thank you for your patience.

Mark A. Hanson @hansonmark.bsky.social · Jun 3

URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯

Any lab using @flybase.bsky.social please donate using the link in post below.

This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.

Marc Dionne @marcsdionne.bsky.social · Jun 3

My lab studies bacterial infections. We spend a lot of time looking at (or for) species-specific genetic and genomic databases for hosts and microbes. FlyBase is the best of all—there is literally no comparison. Its existence is under threat. Please donate.
www.philanthropy.cam.ac.uk/give-to-camb...

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Development, Regeneration and Neurophysiology @drn-sheffield.bsky.social · May 28

Today’s speaker in our DRN external seminar series is Dr Thorsten Boroviak (PDN, University of Cambridge) @pdncambridge.bsky.social , who will talk on early embryonic development in primates.

Host: Anestis Tsakiridis @tsakiridis.bsky.social

All welcome!

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Reposted by Anestis Tsakiridis

Development, Regeneration and Neurophysiology @drn-sheffield.bsky.social · May 21

Congratulations to Dr Claire Turner @molmicrosheffield.bsky.social and DRN's Professor Ivana Barbaric on their excellent talks in the University of Sheffield @sheffielduni.bsky.social School of Biosciences Inaugural Lecture series today.

www.sheffield.ac.uk/biosciences/...

www.thebarbariclab.com

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Regen CTC @regenctc.bsky.social · May 19

The UK Stem Cell Network has just launched registrations for the meeting in September: Find out more by visiting ukstemcellnetwork.org/2025-confere...

Early-bird deadline is 23rd June

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