Lightnews — Scholar-powered news

Reposted by Vanessa Coelho-Santos

Hao Yin @haoyin.bsky.social · 7d

Mind blowing mechanotherapy of aged embryo 🤯👹

Kate Cavanaugh @katecavanaugh.bsky.social · 7d

See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...

4 13

Vanessa Coelho-Santos @vcoelhosantoslab.bsky.social · 8d

This is the wrap-up of #VCoelhoSantosLab at #NEI25 ✨ European Researchers’ Night!
See you next year in Coimbra with more #science, #brains, #bloodvessels, games & fun! 🧠

@ucoimbra.bsky.social @eurobioimaging.bsky.social

1 4

Vanessa Coelho-Santos @vcoelhosantoslab.bsky.social · 14d

The #VCOELHOSANTOSLAB is recruiting a research fellow to join the project "BarriersReveal – Unveiling sex-specific patterns in the neonatal brain barriers".

More info & application submission: apply.uc.pt/IT137-25-363

Application deadline: October 13, 2025

@ucoimbra.bsky.social #neonatalbrain

4 6

Reposted by Vanessa Coelho-Santos

Society for Developmental Biology @socdevbio.bsky.social · Sep 5

✨Nervous about development? Don’t be! 🧠 E13.5 🐁 embryo showing nerves (🩵) and endothelial cells (💙) weaving together in the developing pup 🔬 image by Nathan Burns 🧪 #FluorescenceFriday #DevBio #MouseEmbryo

2 19 93

Vanessa Coelho-Santos @vcoelhosantoslab.bsky.social · Sep 4

@ucoimbra.bsky.social @eurobioimaging.bsky.social

Vanessa Coelho-Santos @vcoelhosantoslab.bsky.social · Sep 4

Over the moon to say I’ve been awarded an #ERCstg from @erc.europa.eu !

#AngioArchitects will explore how blood vessels migrate & connect using 🔬 #liveimaging, with the hypothesis that #microglia are the “uber” driving them! 🧠🩸

Positions opening in 2026, stay tuned!

European Research Council (ERC) @erc.europa.eu · Sep 4

In 2025, successful ERC Starting Grant applicants have 51 different nationalities and will carry out their projects in 25 countries. This round of grants is estimated to create some 3,000 jobs within the teams of the new grantees.

More facts and figures 👉 buff.ly/ixs2NRf

4 1 16

Reposted by Vanessa Coelho-Santos

The Transmitter @thetransmitter.bsky.social · Sep 4

Astrocyte networks are much larger than previously thought, which “flips the way we think about astrocytes and what their networks may mean,” says @liddelowsa.bsky.social.

By @callimcflurry.bsky.social

#neuroskyence

www.thetransmitter.org/astrocytes/a...

11 34

Reposted by Vanessa Coelho-Santos

Universidade de Coimbra @ucoimbra.bsky.social · Sep 4

A investigadora da @ucoimbra.bsky.social, Vanessa Coelho-Santos, conquistou uma Starting Grant do European Research Council, que ultrapassa os dois milhões de euros! 👏 👏 👏

#UCoimbra #InvestigaçãoUC #ERCStG @erc.europa.eu

Cientista da UC ganha prestigiada bolsa do Conselho Europeu de Investigação de mais de dois milhões de euros

Vanessa Coelho-Santos conquistou uma Starting Grant para desvendar, ao longo de cinco anos, novas informações sobre o desenvolvimento do cérebro de recém-nascidos, de forma a compreender que fenómenos...

noticias.uc.pt

2 3

Vanessa Coelho-Santos @vcoelhosantoslab.bsky.social · Sep 4

@ucoimbra.bsky.social @eurobioimaging.bsky.social

Vanessa Coelho-Santos @vcoelhosantoslab.bsky.social · Sep 4

@ucoimbra.bsky.social @eurobioimaging.bsky.social

Reposted by Vanessa Coelho-Santos

Hellmut Augustin @hellmutaugustin.bsky.social · Sep 4

Three new @erc.europa.eu Starting Grants for vascular researchers: Congratulations to Vanessa Coelho-Santos (@vcoelhosantoslab.bsky.social) for "AngioArchitects“ (LS5], Leire Bejarano for "MetaVasc" (LS4], and Mahak Singhal for "Vascular Rhythm" (LS4). Great success!

1 2 9

Vanessa Coelho-Santos @vcoelhosantoslab.bsky.social · Sep 4

@evborg.bsky.social mock interview was key on this achievement!! 🔬 Thanks so much for your support and hard questions!! 😅

Reposted by Vanessa Coelho-Santos

Siegenthaler Lab @siegenthalerlab.bsky.social · Jul 26

I'm sure we all know someone (🙋🏻‍♀️) or have personally benefited from early detection cancer screening, like breast & colon cancer, that are increasingly seen in younger people. And mandated to be paid for by insurance, reducing out-of-pocket 💰. The benefit is huge, important 🧵 on USPSTF in jeopardy.

BK. Titanji @boghuma.bsky.social · Jul 26

1/ This is a long 🧵, so buckle up & I hope you read till the end.
The HHS Secretary, is planning to remove all 16 members of the USPSTF the expert panel that decides which preventive services (cancer screenings, HIV prevention meds) must be covered by insurers under the Affordable Care Act.

3 8

Vanessa Coelho-Santos @vcoelhosantoslab.bsky.social · Jul 25

Glad to meet in person Alessandra Viale and Erika Cerutti! Was a lovely surprise…I had opportunity to show my lab and talk about our science. Amazing be part of @eurobioimaging.bsky.social as #scientificambassador 🔬🧠

eurobioimaging.bsky.social @eurobioimaging.bsky.social · Jul 23

Our Med-Hub colleagues got to visit the Portuguese Brain Imaging Network (BIN) Node in Coimbra. 🇵🇹 It offers open access to PET & MRI for a variety of preclinical and human imaging applications. 🧠🫀 Thanks to the CIBIT team for this visit!
Learn more ⤵️
www.eurobioimaging.eu/news/visitin...

1 2

Vanessa Coelho-Santos @vcoelhosantoslab.bsky.social · Jul 25

🎓 Internship season wrapped! Huge congrats to Zoé Morgado (July 14) and Filipe Ponte (July 23) for defending their bachelor theses! Zoé (Biomed Eng) and Filipe (Biotech) explored #cerebrovascular and #neuroimaging at #VCoelhoSantosLab.

1

Reposted by Vanessa Coelho-Santos

Hao Yin @haoyin.bsky.social · Jul 23

Amazing #2PM real-time morpho-dynamic responses of microglia to laser-induced parenchymal/vascular injury in🐭🧠

Age-dependent reaction speed
👉Parenchymal injury
Adult > Aged/Neonatal
👉Vascular injury
Adult/Aged > Neonatal

@vcoelhosantoslab.bsky.social #CellRep 2025
www.cell.com/cell-reports...

2 13

Vanessa Coelho-Santos @vcoelhosantoslab.bsky.social · Jul 22

Some 🧠 of #VCoelhoSantosLab!! Here we study the #neurogliovascularunit using #liveimaging! We are 🧠 imaging experts!! 🔬#worldbrainday2025 #scientificambassador @eurobioimaging.bsky.social @ucoimbra.bsky.social

4 15

Reposted by Vanessa Coelho-Santos

Axel Montagne @axelmontagne.bsky.social · Jul 22

🚨 Review Alert

*Walking on the tightrope: the shared roles of the bridging pericytes in the brain*

Congratulations Audrey Chagnot!! 🥳

Bias aside, this feels like a really meaningful piece for the cerebrovascular field! 😊

www.frontiersin.org/journals/cel...

Frontiers | Walking on the tightrope: the shared roles of the bridging pericytes in the brain

The vasculature of the central nervous system (CNS) is a highly specialized structure that delivers oxygen and nutrients to energy-demanding neural cells whi...

www.frontiersin.org

7 15

Vanessa Coelho-Santos @vcoelhosantoslab.bsky.social · Jul 18

#NewResearch from the #VcoelhoSantosLab and #ShihLab used #two-photon live imaging to reveal how #microglia 🧠 evolve across across #lifespan.

Key findings:
👶 Neonatal: Active but clumsy
🧍‍♂️ Adult: Calm but sharp
👵 Aged: Quiet and slow

@ucoimbra.bsky.social @lacaixa.bsky.social

Physiological and injury-induced microglial dynamics across the lifespan

Tieu, T. et al. leveraged in vivo two-photon live imaging of microglia, the brain’s resident immune cells, to reveal striking differences in their morphology, basal dynamics, and injury responses acro...

www.cell.com

1 5 15

Vanessa Coelho-Santos @vcoelhosantoslab.bsky.social · Jul 8

#VCoelhoSantosLab at @gliameeting.bsky.social represented by the Magda Rodrigues! 🧠🔬
#glia2025
#gliovascular
@ucoimbra.bsky.social

2

Reposted by Vanessa Coelho-Santos

Shane Liddelow @liddelowsa.bsky.social · Jul 3

#GliaPapers #GliaJuly2025
JULY COVER
Stochastically labeled astrocytes (cyan) and Müller glia (magenta) contacting blood vessels (orange) and neural cell bodies and axons bundles (green) in a mouse retina. (see Holden, JM, et al, doi.org/10.1002/glia...)

1 4 36

Vanessa Coelho-Santos @vcoelhosantoslab.bsky.social · Jul 3

Today Catarina, Maria, Clara, and Carolina presented their bachelor internship projects. It was truly a pleasure to watch you grow and to see the passion for blood vessels taking root in each of you. Wishing you all the success in your futures! #VCoelhoSantosLab

1 2

Vanessa Coelho-Santos @vcoelhosantoslab.bsky.social · Jul 1

See you Thursday!!
@ucoimbra.bsky.social

Astrocyte Cafe @astrocytecafe.bsky.social · Jul 1

Join us this Thursday to hear some pretty cool science by @vcoelhosantoslab.bsky.social‬
and @szewczyklukasz.bsky.social‬
😍👇👇👇

As usual, you need to subscribe to our mailing list to receive the link! Or email us at [email protected] ;)

@

1

Vanessa Coelho-Santos @vcoelhosantoslab.bsky.social · Jun 26

See you all tomorrow!! @au.dk @ucoimbra.bsky.social

1 4

Vanessa Coelho-Santos @vcoelhosantoslab.bsky.social · Jun 13

Wake up moment!!! 🎥✨
#Astrocyte calcium bursts light up as the brain shifts from sleep to wakefulness in postnatal mice. 👉 Pay attention to the glowing #vasculature. ⚡
#NeonatalBrain #NeurovascularCoupling #liveimaging @ucoimbra.bsky.social @lacaixa.bsky.social

1 6