Ville Kujala
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Ville Kujala
@villekujala.bsky.social
I bring you…STAN
Science, Technology, Art, and Nature
Reposted by Ville Kujala
Manipulating the activity of these immune cells could provide a way to reduce the severity of heart attacks

go.nature.com/4jtQNxr
Putting immune cells into ‘night mode’ reduces heart-attack damage
Drugs that limit the activity of cells called neutrophils could make heart attacks less severe without compromising the immune system.
go.nature.com
January 8, 2026 at 3:21 PM
Reposted by Ville Kujala
Nature research paper: Soft biodegradable implants for long-distance and wide-angle sensing

go.nature.com/4suJaut
Soft biodegradable implants for long-distance and wide-angle sensing - Nature
A soft, biodegradable, wireless sensing device can monitor pressure, temperature and strain over long distances (up to 16 cm), maintaining accuracy across varying positions and angles.
go.nature.com
January 8, 2026 at 4:09 PM
Reposted by Ville Kujala
New discoveries are reshaping how scientists understand the molecular connections between the extracellular matrix and lysosomes—and the resulting implications for research and therapeutics for neurodegenerative disorders.

Learn more in this #ScienceSignaling Review: https://scim.ag/3Yi2sFS
Decoding extracellular matrix–lysosome cross-talk and its implications for neurodegenerative diseases
Reciprocal signaling between intracellular lysosomes and the extracellular matrix supports brain health.
scim.ag
January 2, 2026 at 4:14 PM
Reposted by Ville Kujala
A 3D printed guide that reconnects right vagus nerve and heart preserved cardiac function and helped regrow resected nerve in minipigs, with therapeutic potential for thoracic surgery and transplantation.

Learn more in #ScienceTranslationalMedicine: https://scim.ag/49eworw
Reconnecting the vagus nerve to the heart through nerve conduit preserves cardiac function in a minipig model of right cardiac vagotomy
Partial repair of cardiac right vagus nerve using an implantable conduit after vagal resection limits cardiac tissue damage and dysfunction.
scim.ag
December 29, 2025 at 4:00 PM
Reposted by Ville Kujala
Reposted by Ville Kujala
A protein that cuts double-stranded DNA contributes to chromosome scrambling in human cancer cells.

Learn more in a new #SciencePerspective: https://scim.ag/4aKry7p
Chromosome shattering in cancer
A protein that cuts double-stranded DNA contributes to chromosome scrambling in human cancer cells
scim.ag
December 25, 2025 at 7:07 PM
Reposted by Ville Kujala
An in vivo imaging technique can track the way molecules move through the nuclear pore complex

go.nature.com/3KODM4A
Live-cell super-resolution microscopy reveals how molecules enter and exit the nucleus
The nuclear pore complex is the gateway to the nucleus of cells. Now an in vivo imaging technique can track the way in which molecules move through this complex.
go.nature.com
December 22, 2025 at 4:38 PM
Reposted by Ville Kujala
Now online! A 3D in vitro model for studying human implantation and implantation failure
A 3D in vitro model for studying human implantation and implantation failure
A 3D in-chip implantation model is developed using a bioengineered human endometrioid and human blastoids or blastocysts and used to identify candidate compounds that can enhance implantation rates in endometrioids derived from patients experiencing recurrent implantation failure.
dlvr.it
December 23, 2025 at 4:00 PM
Kidney progenitor assembloids demonstrated filtration, hormone secretion, and urine production at levels comparable to newborn kidneys. Human assembloids successfully modeled polycystic kidney disease pathology including cyst formation, inflammation, and fibrosis.

www.cell.com/cell-stem-ce...
Spatially patterned kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling
Recapitulating the self-assembly of kidney progenitors, Huang, Medina, He, Zeng, and colleagues have developed mouse and human kidney progenitor assembloids, exhibiting enhanced cellular complexity, s...
www.cell.com
December 15, 2025 at 11:48 PM
Reposted by Ville Kujala
A scaffold-free bioprinting approach achieves physiological cell densities, and is used to print in vitro models of heart and liver structures, and neural circuits #NBThighlight www.cell.com/cell/fulltex...
Biomaterial-minimalistic photoactivated bioprinting of cell-dense tissues
We developed a bioprinting strategy that turns living cells into cell-only bioinks, enabling light-based 3D bioprinting of tissues at native, ultrahigh cell densities (up to ∼109 cells mL−1) to rapidl...
www.cell.com
December 9, 2025 at 2:46 PM
Reposted by Ville Kujala
Now online! Membrane potential mediates the cellular response to mechanical pressure
Membrane potential mediates the cellular response to mechanical pressure
Cells in tissues need to know when to start growing and when to stop growing to quickly heal wounds but prevent tumorous overgrowth. Membrane potential allows cells to sense physical forces, including those from neighboring cells, and thereby regulates growth.
dlvr.it
December 2, 2025 at 11:39 PM
Reposted by Ville Kujala
Kathrin Marchenko is a textile artist recognized for her expressive embroidery on delicate tulle fabric.
Working in a “painting with thread” style, she crafts portraits, anatomical forms & airy figures that appear to float inside wooden hoops, merging traditional craft with fine art elegance.
November 29, 2025 at 2:39 PM
Reposted by Ville Kujala
Ischaemic stroke remains a leading cause of disability. This article discusses the design of biomaterials that can engage and modulate pro-repair mechanisms in the brain to improve repair after ischaemic stroke:
Biology-driven material design for ischaemic stroke repair - Nature Reviews Bioengineering
Rehabilitation after ischaemic stroke can promote only limited recovery for many patients with stroke. This Review discusses how the distinctly reparative environment of the subacute time window after stroke can inform the design of biology-driven biomaterial-based stroke therapies.
go.nature.com
November 25, 2025 at 3:06 PM
Reposted by Ville Kujala
Generative AI meets the genome
Genes with related functions cluster together, and the AI uses that.
arstechnica.com
November 21, 2025 at 9:27 PM
Nature interviewed six AI leaders on where the technology is heading. Perspectives from Microsoft, Google DeepMind, Anthropic, and UN representatives on both development ambitions and societal adaptation.

www.nature.com/immersive/d4...
The future of AI
Artificial intelligence is flying high. Nature asked leading innovators what they think will happen next.
www.nature.com
November 22, 2025 at 12:38 AM
Reposted by Ville Kujala
Biopharma’s reawakened interest in cardiovascular diseases spans new targets and modalities, with more convenient formulations to boost access and adherence go.nature.com/4r9HhTw
Heart matters: new treatments, tools and access channels - Nature Biotechnology
Biopharma’s reawakened interest in cardiovascular diseases spans new targets and modalities, with more convenient formulations to boost access and adherence.
go.nature.com
November 21, 2025 at 6:55 PM
“With this new approach, the agency is essentially shifting the regulatory focus from approving each individual drug to clearing the therapeutic platform for some individualized treatments based on the same technology.”

www.fiercebiotech.com/biotech/fdas...
Prasad, Makary unveil new FDA path for accelerating custom gene editing therapies
In a highly anticipated article, FDA officials Vinay Prasad, M.D., and Martin Makary, M.D., outlined a novel regulatory pathway that could trigger a seismic shift in how bespoke gene editing therap | ...
www.fiercebiotech.com
November 12, 2025 at 10:57 PM
In this HBR article Sir Andrew Likierman identifies six elements of good judgment: active listening, seeking challenging advisers, broad experience, countering biases, expanding options, and execution feasibility. These skills separate sound decisions from luck.

hbr.org/2020/01/the-...
The Elements of Good Judgment
Judgment—the ability to combine personal qualities with relevant knowledge and experience to form opinions and make decisions—is “the core of exemplary leadership,” according to Noel Tichy and Warren ...
hbr.org
November 12, 2025 at 4:38 PM
Reposted by Ville Kujala
Big pharma shares its machine learning models with biotechs, but awaits definitive data on success of artificial intelligence-generated drugs www.nature.com/articles/s41...
Drugmakers share data to feed voracious foundation models - Nature Biotechnology
Big pharma shares its machine learning models with biotechs, but awaits definitive data on success of artificial intelligence-generated drugs.
www.nature.com
November 10, 2025 at 9:09 PM
AHA 2025: Amgen’s Repatha cut first heart attacks by 36%, Merck’s oral PCSK9 pill matched injectables, and gene therapies from Intellia and CRISPR showed durable cholesterol and triglyceride reductions alongside Ionis’ 72% triglyceride drop.

www.biospace.com/drug-develop...
Amgen, Merck, Novo, More Take Cardiovascular Benefits to New Heights at AHA 2025
Data presented at this year’s American Heart Association Scientific Sessions in New Orleans underline rapid advancements in the cardiovascular field.
www.biospace.com
November 11, 2025 at 4:35 PM
“The user receives an instruction to copy a string of text, open a terminal window, paste it in, and press Enter.”

Never do this. Real CAPTCHA doesn’t require command line operations. If you get a sketchy email from a hotel, call them.

arstechnica.com/security/202...
ClickFix may be the biggest security threat your family has never heard of
Relatively new technique can bypass many endpoint protections.
arstechnica.com
November 11, 2025 at 3:31 PM
Reposted by Ville Kujala
Nature research paper: Spatial dynamics of brain development and neuroinflammation

go.nature.com/4hO36DQ
Spatial dynamics of brain development and neuroinflammation - Nature
A tri-omic atlas of the mouse brain from postnatal day 0 to P21 reveals that layer-specific projection neurons have a role in coordinating axonogenesis and myelination.
go.nature.com
November 10, 2025 at 6:27 PM
Ranked “top genes” can look important partly because of gene length and statistical structure, so high rank doesn’t always mean central to the biology
November 10, 2025 at 7:36 PM