We just published this paper of which I am immensely proud: www.nature.com/articles/s41...

In the study, we uncover how the enzyme MPO disassembles #nucleosomes in a process called NETosis, a funky mechanism of #neutrophils to kill #pathogens that you might have never heard of.

Let's dive in... 🧵

My final postdoctoral work will come out very soon, so watch this space 🧐.

In Amsterdam, I aim to decipher the molecular mechanisms of (cancer)-cell migration and adhesion using structural biology approaches. Positions available soon, so please reach out when you are interested! 😁

This marks the end of >4.5 years as a postdoctoral researcher at the @mpi-dortmund.bsky.social. Massive thanks to my advisor @raunser-lab.bsky.social for the invaluable guidance and support; and the entire department for making it an unforgettable experience!

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Thrilled to announce that from tomorrow (October 1st), I'll start as a junior group leader at the Netherlands Cancer Institute (NKI) @nkinl.bsky.social in Amsterdam 😄.

www.nki.nl/news-events/...

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Featuring #AlphaBridge features from @alvarezsalmoral.bsky.social, with @jonasteuwen.bsky.social and team, our new work from @nkinl.bsky.social nl.bsky.social @oncodeinstitute.bsky.social . Have a look at ahmpc.eu for more!

Nature research paper: Molecular mechanism of ultrafast transport by plasma membrane Ca2+-ATPases

go.nature.com/3HpdTqq

The video takes more than half a minute for illustrative purposes. However, these PMCA2-NPTN complexes can in reality pump calcium out of the cell at a speed of 5,000 (! 🤯) ions per second.

Happy to have made a tiny contribution to this work (including the shown movie 😄). Amazing work by Fakler lab @uni-freiburg.de and @raunser-lab.bsky.social @mpi-dortmund.bsky.social about Ca-ion transport by PMCA2-NPTN complexes, now out in @nature.com

www.nature.com/articles/s41...

Excited to share our latest work with @simonbullock11.bsky.social! We looked at how diverse mRNAs get selected for subcellular localization and it turns out that a single protein can recognize different RNA elements using shared features that weren’t apparent before.
www.biorxiv.org/content/10.1...

Great story, congratulations!

Some happy news. Pleased to see our paper showing how afadin strengthens cytoskeletal engagement by the cadherin-catenin cell adhesion complex out in Science Advances: bit.ly/3EFpD6h

Cool story, congrats!!

Working on actin cytoskeleton and Arp2/3 complex? Check out our latest work～https://www.biorxiv.org/content/10.1101/2025.01.31.635869v1
In this work, we found SPIN90 forms a dimer, facilitating bidirectional actin filament nucleation by activating two Arp2/3 complex #Cryo-EM #Actin #Arp2/3

Thank you 😁!

Danke schön mein Sohn. Hope everything is well in Boston.

My first post on this forum! 😄

I am happy to share that our #openaccess review on the #molecular mechanisms of #actin filament polymerization and dissasembly is now online @cp-trendscellbio.bsky.social

www.cell.com/trends/cell-...

Big thanks to my amazing colleagues in Dortmund