Will Matlock
@wtmatlock.bsky.social
540 followers
410 following
36 posts
Wellcome Early-Career Fellow @milnerevolution.bsky.social working on mobile genetic element genomics (he/him) 🏳️⚧️🇵🇸
Formerly @biology.ox.ac.uk and @modmedmicro.bsky.social
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Reposted by Will Matlock
Reposted by Will Matlock
Reposted by Will Matlock
Reposted by Will Matlock
Craig MacLean
@craigmaclean.bsky.social
· Jul 29
Plasmids link antibiotic resistance genes and phage defense systems in E. coli
Phage therapy has been proposed as an alternative to antibiotics to treat resistant infections. However, we have a limited understanding of how antibiotic resistance genes (ARGs) associate with bacter...
www.biorxiv.org
Reposted by Will Matlock
Reposted by Will Matlock
The Lancet
@thelancet.com
· Jun 12
Reinforcing social safety for transgender and non-binary communities amidst global legislative threats
In 2017, we called for multisector public health initiatives to address discrimination
and violence against transgender and non-binary communities, offering tangible recommendations
for protecting the...
tinyurl.com
Reposted by Will Matlock
Zamin Iqbal
@zaminiqbal.bsky.social
· May 19
Reposted by Will Matlock
Reposted by Will Matlock
Will Matlock
@wtmatlock.bsky.social
· Jan 7
Reposted by Will Matlock
Reposted by Will Matlock
Alan McNally
@alanmcn1.bsky.social
· Dec 6
Global genomic epidemiology of bla
GES-5 carbapenemase-associated integrons
Antimicrobial resistance (AMR) gene cassettes comprise an AMR gene flanked by short recombination sites (attI and attC or attC and attC). Integrons are genetic elements able to capture, excise and shu...
www.microbiologyresearch.org
Will Matlock
@wtmatlock.bsky.social
· Dec 3
Will Matlock
@wtmatlock.bsky.social
· Dec 3
Reposted by Will Matlock
Jamie Hall
@jpjhall.bsky.social
· Dec 3
A chromosomal mutation is superior to a plasmid-encoded mutation for plasmid fitness cost compensation
Plasmids spread important traits in microbiomes but impose fitness costs on their hosts. This study of the ecological consequences of plasmid-bacterial compensatory evolution reveals benefits to bacte...
journals.plos.org
Reposted by Will Matlock
Zamin Iqbal
@zaminiqbal.bsky.social
· Nov 15
AllTheBacteria - all bacterial genomes assembled, available and searchable
The bacterial sequence data publicly available at the global DNA archives is a vast source of information on the evolution of bacteria and their mobile elements. However, most of it is either unassemb...
www.biorxiv.org
Reposted by Will Matlock
Eduardo Rocha
@epcrocha.bsky.social
· Nov 11
Expanding the diversity of origin of transfer-containing sequences in mobilizable plasmids - Nature Microbiology
Characterization of known plasmid oriT features facilitates identification of 21 oriT-containing sequence families which, alongside candidate sequence validation, expands our understanding of plasmid ...
www.nature.com
Will Matlock
@wtmatlock.bsky.social
· Oct 23
Reposted by Will Matlock
Zamin Iqbal
@zaminiqbal.bsky.social
· Oct 15
Will Matlock
@wtmatlock.bsky.social
· Oct 7
🎃nisillos
@onisillos.bsky.social
· Oct 5
Exploring uncatalogued genetic variation in antimicrobial resistance gene families in Escherichia coli: an observational analysis
We highlight substantial uncatalogued genetic variation with respect to known ARGs,
although a relatively small proportion of these alleles are repeatedly observed in
a large international dataset sug...
www.thelancet.com