p53 inactivation drives breast cancer metastasis to the brain through SCD1 upregulation and increased fatty acid metabolism www.nature.com/articles/s41...
p53 inactivation drives breast cancer metastasis to the brain through SCD1 upregulation and increased fatty acid metabolism - Nature Genetics
This study associates p53 loss and brain metastasis in breast cancer. Mechanistically, p53-null tumors recruit astrocytes that provide substrates for enhanced fatty acid synthesis via upregulated SCD1...
www.nature.com
January 7, 2026 at 4:44 AM
p53 inactivation drives breast cancer metastasis to the brain through SCD1 upregulation and increased fatty acid metabolism www.nature.com/articles/s41...
We just want to come clean with 2 ace-brain things.
1. we forgot getting cow girl art implies a breast milk kink.
2. we forgot getting horse girl art implies a horse cock kink.
1. we forgot getting cow girl art implies a breast milk kink.
2. we forgot getting horse girl art implies a horse cock kink.
January 6, 2026 at 7:45 PM
We just want to come clean with 2 ace-brain things.
1. we forgot getting cow girl art implies a breast milk kink.
2. we forgot getting horse girl art implies a horse cock kink.
1. we forgot getting cow girl art implies a breast milk kink.
2. we forgot getting horse girl art implies a horse cock kink.
not my brain inserting:
"THE DAY IS SAVED THANKS TO FRIED CHICKEN BREAST!"
"THE DAY IS SAVED THANKS TO FRIED CHICKEN BREAST!"
three cartoon characters are standing in front of a pink heart
Alt: three cartoon characters are flying in front of a pink heart
media.tenor.com
January 6, 2026 at 5:17 PM
not my brain inserting:
"THE DAY IS SAVED THANKS TO FRIED CHICKEN BREAST!"
"THE DAY IS SAVED THANKS TO FRIED CHICKEN BREAST!"
Me: alright brain, we're on low sleep today, so we need to lock tf in
My brain: got it, okay, let's-
My intrusive thoughts: if you made cheese from Medusa's breast milk, would that be gorgonzola?
My brain: got it, okay, let's-
My intrusive thoughts: if you made cheese from Medusa's breast milk, would that be gorgonzola?
January 6, 2026 at 3:44 PM
Me: alright brain, we're on low sleep today, so we need to lock tf in
My brain: got it, okay, let's-
My intrusive thoughts: if you made cheese from Medusa's breast milk, would that be gorgonzola?
My brain: got it, okay, let's-
My intrusive thoughts: if you made cheese from Medusa's breast milk, would that be gorgonzola?
A newly identified mechanism explains how breast cancer cells metastasize to the brain, highlighting the role of p53 loss and fatty acid synthesis, and suggesting new targets for treatment and monitoring. doi.org/hbht68
For the first time, a mechanism enabling breast cancer to metastasize to the brain has been deciphered
A large-scale international study, led by researchers from the Gray Faculty of Medical and Health Sciences at Tel Aviv University, has uncovered a mechanism that allows breast cancer to send metastases to the brain—a highly lethal occurrence for which there is currently no effective treatment.
medicalxpress.com
January 5, 2026 at 8:08 PM
A newly identified mechanism explains how breast cancer cells metastasize to the brain, highlighting the role of p53 loss and fatty acid synthesis, and suggesting new targets for treatment and monitoring. doi.org/hbht68
<tears of relief>
It doesn't matter that the MRI didn't cause the cancer, I still freak out every year because the MRI is how they caught the cancer and my brain doesn't see the difference.
It doesn't matter that the MRI didn't cause the cancer, I still freak out every year because the MRI is how they caught the cancer and my brain doesn't see the difference.
January 5, 2026 at 3:52 PM
<tears of relief>
It doesn't matter that the MRI didn't cause the cancer, I still freak out every year because the MRI is how they caught the cancer and my brain doesn't see the difference.
It doesn't matter that the MRI didn't cause the cancer, I still freak out every year because the MRI is how they caught the cancer and my brain doesn't see the difference.
To give you a bit of insight into how my weird-ass brain comes up with these crazy ideas, I've read that its possible to have an accessory nipple/breast form anywhere from the armpit to the inner thigh, and I immediately wondered: "what would it look like if there weren't limbs in the way?"
@mapple-hitori.bsky.social has gotten around to coloring my new #legless #multibreast #OC. I've decided to name her #🍈Sariyah.
She was born without legs and has polymastia with accessory breasts growing from what exists of her thighs.
She was born without legs and has polymastia with accessory breasts growing from what exists of her thighs.
January 4, 2026 at 11:25 PM
To give you a bit of insight into how my weird-ass brain comes up with these crazy ideas, I've read that its possible to have an accessory nipple/breast form anywhere from the armpit to the inner thigh, and I immediately wondered: "what would it look like if there weren't limbs in the way?"
A Tilly thing for @feelinimpish.bsky.social because she latched onto every vulnerable part of my brain and hijacked it and she scares me in all the best ways I love her
[ #Nsfw | #BreastExpansion | #Sizesky ]
[ #Nsfw | #BreastExpansion | #Sizesky ]
January 4, 2026 at 6:25 PM
A Tilly thing for @feelinimpish.bsky.social because she latched onto every vulnerable part of my brain and hijacked it and she scares me in all the best ways I love her
[ #Nsfw | #BreastExpansion | #Sizesky ]
[ #Nsfw | #BreastExpansion | #Sizesky ]
Made food to help fight the brain gremlins. Today has been...a day.
Chickpea and spinach rice pilaf, cooked in coconut milk and indian spices, with yogurt sauce on top. Served with golden curry chicken breast
Come and get it boys
Chickpea and spinach rice pilaf, cooked in coconut milk and indian spices, with yogurt sauce on top. Served with golden curry chicken breast
Come and get it boys
January 2, 2026 at 10:59 PM
Made food to help fight the brain gremlins. Today has been...a day.
Chickpea and spinach rice pilaf, cooked in coconut milk and indian spices, with yogurt sauce on top. Served with golden curry chicken breast
Come and get it boys
Chickpea and spinach rice pilaf, cooked in coconut milk and indian spices, with yogurt sauce on top. Served with golden curry chicken breast
Come and get it boys
Trisha Goddard, 68, reveals metastatic breast cancer has not spread to her brain following scan trib.al/oEBsJi8
Trisha Goddard reveals metastatic breast cancer has not spread
Trisha Goddard shared a defiant and upbeat update with fans on Friday, after receiving the results that her metastatic breast cancer has not spread to her brain.
www.dailymail.co.uk
January 2, 2026 at 7:32 PM
Trisha Goddard, 68, reveals metastatic breast cancer has not spread to her brain following scan trib.al/oEBsJi8
The findings offer new hope for treating aggressive brain metastases, including triple-negative breast cancer, where conventional therapies often fail.
Read how nanomedicine is learning to work with the brain rather than against it.
Read how nanomedicine is learning to work with the brain rather than against it.
Why Brain Tumours Remain One Of Medicine’s Hardest Problems – The Science Matters
What if cancer drugs could enter the brain naturally? This research shows how HER3-guided nanobioparticles make it possible.
thesciencematters.org
January 2, 2026 at 10:06 AM
The findings offer new hope for treating aggressive brain metastases, including triple-negative breast cancer, where conventional therapies often fail.
Read how nanomedicine is learning to work with the brain rather than against it.
Read how nanomedicine is learning to work with the brain rather than against it.
"Room for seconds?" she offers, reminding you of her milk, her breast now the only thing you could see.
You had to stop drinking from her big boobies, you thought, before the spell was renewed and without any further input from your brain you got back to gulping down her magical milk...
You had to stop drinking from her big boobies, you thought, before the spell was renewed and without any further input from your brain you got back to gulping down her magical milk...
January 1, 2026 at 7:32 PM
"Room for seconds?" she offers, reminding you of her milk, her breast now the only thing you could see.
You had to stop drinking from her big boobies, you thought, before the spell was renewed and without any further input from your brain you got back to gulping down her magical milk...
You had to stop drinking from her big boobies, you thought, before the spell was renewed and without any further input from your brain you got back to gulping down her magical milk...
The rub: Alcohol is bad for you. “We now know that even modest drinking is linked to a higher risk of developing certain cancers such as breast, colorectal and esophageal cancers, as well as brain changes and dementia, heart problems and sleep problems.”
Many people think red wine is better for you than white wine or other types of alcohol. The notion was partly born from studies — some of which have been disputed.
Here’s what new evidence says:
Here’s what new evidence says:
Is red wine better for you than white? The answer may surprise you.
If you’re confused about alcohol, that’s understandable. Here’s what you need to know about red wine versus white wine in terms of health benefits.
www.washingtonpost.com
January 1, 2026 at 4:19 AM
The rub: Alcohol is bad for you. “We now know that even modest drinking is linked to a higher risk of developing certain cancers such as breast, colorectal and esophageal cancers, as well as brain changes and dementia, heart problems and sleep problems.”
Or breast cancer that had metastasized to her brain, I don’t recall
December 31, 2025 at 11:19 PM
Or breast cancer that had metastasized to her brain, I don’t recall
Not at all TMI. My sister had a rare aggressive form of breast cancer in 2020 that spread to her brain. Covid took her out before the cancer did. She had been brilliant. I miss her deeply.
December 31, 2025 at 4:34 AM
Not at all TMI. My sister had a rare aggressive form of breast cancer in 2020 that spread to her brain. Covid took her out before the cancer did. She had been brilliant. I miss her deeply.
I lost 3 aunts to cancer. Only one was over 50. Colon, Brain and Breast.
Cancer is vicious.
Cancer is vicious.
December 30, 2025 at 11:28 PM
I lost 3 aunts to cancer. Only one was over 50. Colon, Brain and Breast.
Cancer is vicious.
Cancer is vicious.
Bounce bounce bounce~ another few bounce echoing in your brain. Jiggle jiggle jiggle~ so soft and squishy and warm to squeeze. Wobble wobble wobble~ just sinking away into happy empty booby bliss. And then when you're nice and deep for tits, wake up, with a nice new breast fixation for a bit<3
December 30, 2025 at 7:49 PM
Bounce bounce bounce~ another few bounce echoing in your brain. Jiggle jiggle jiggle~ so soft and squishy and warm to squeeze. Wobble wobble wobble~ just sinking away into happy empty booby bliss. And then when you're nice and deep for tits, wake up, with a nice new breast fixation for a bit<3
Trying to train my brain so I can make comics without losing focus half way through, so heres a lil Ganyu sequence.
December 29, 2025 at 9:39 PM
Trying to train my brain so I can make comics without losing focus half way through, so heres a lil Ganyu sequence.
p53 inactivation drives breast cancer metastasis to the brain through SCD1 upregulation and increased fatty acid metabolism
https://www.newsbeep.com/us/376551/
Harbeck, N. et al. Breast cancer. Nat. Rev. Dis. Primers 5, 66 (2019). Article PubMed Google Scholar Chen,…
https://www.newsbeep.com/us/376551/
Harbeck, N. et al. Breast cancer. Nat. Rev. Dis. Primers 5, 66 (2019). Article PubMed Google Scholar Chen,…
p53 inactivation drives breast cancer metastasis to the brain through SCD1 upregulation and increased fatty acid metabolism - United States News Beep
Harbeck, N. et al. Breast cancer. Nat. Rev. Dis. Primers 5, 66 (2019).
www.newsbeep.com
December 29, 2025 at 9:06 PM
p53 inactivation drives breast cancer metastasis to the brain through SCD1 upregulation and increased fatty acid metabolism
https://www.newsbeep.com/us/376551/
Harbeck, N. et al. Breast cancer. Nat. Rev. Dis. Primers 5, 66 (2019). Article PubMed Google Scholar Chen,…
https://www.newsbeep.com/us/376551/
Harbeck, N. et al. Breast cancer. Nat. Rev. Dis. Primers 5, 66 (2019). Article PubMed Google Scholar Chen,…
I started reading Ranked Competitive Breast Growth and it only took like 8-9ish chapters for the brain worms to start entering my thoughts this book rules
December 29, 2025 at 9:03 PM
I started reading Ranked Competitive Breast Growth and it only took like 8-9ish chapters for the brain worms to start entering my thoughts this book rules
p53 inactivation drives breast cancer metastasis to the brain through SCD1 upregulation and increased fatty acid metabolism
->Nature | More from Lil Dr Glen EcoChat at BigEarthData.ai
->Nature | More from Lil Dr Glen EcoChat at BigEarthData.ai
p53 inactivation drives breast cancer metastasis to the brain through SCD1 upregulation and increased fatty acid metabolism
The authors thank J. Pietenpol (Vanderbilt University Medical Center) for generously sharing isogenic CAL51 cells with various TP53 perturbations; N. Erez (Tel Aviv University), A. Sonneblick (Schneider Children's Medical Center), S. Izraeli (Tel Aviv University) and O. Shoshani (Weizmann Institute)...
www.nature.com
December 29, 2025 at 2:34 PM
I'll def need to give it a listen! Very much up my alley it sounds 💙
I'm a huge fan of things getting a bit *big* x3 so my brain was also going the route of "Tits so big that your body is insignificant enough it might as well not be there"
I'm a huge fan of things getting a bit *big* x3 so my brain was also going the route of "Tits so big that your body is insignificant enough it might as well not be there"
December 29, 2025 at 12:15 PM
I'll def need to give it a listen! Very much up my alley it sounds 💙
I'm a huge fan of things getting a bit *big* x3 so my brain was also going the route of "Tits so big that your body is insignificant enough it might as well not be there"
I'm a huge fan of things getting a bit *big* x3 so my brain was also going the route of "Tits so big that your body is insignificant enough it might as well not be there"
Brain imaging surveillance for patients with metastatic breast cancer: a randomized clinical trial is required to guide practice, published in J Clin Oncol.
👉 Read it before your patients: bit.ly/3Y7Qq1J
👉 Read it before your patients: bit.ly/3Y7Qq1J
December 29, 2025 at 8:52 AM
Brain imaging surveillance for patients with metastatic breast cancer: a randomized clinical trial is required to guide practice, published in J Clin Oncol.
👉 Read it before your patients: bit.ly/3Y7Qq1J
👉 Read it before your patients: bit.ly/3Y7Qq1J
i realized that on monday last week i wore the "sunflower" restaurant shirt i got the last time we had dinner together, in november last year. that was shortly after she finished her breast cancer treatment. but then soon after she found out it had migrated to her brain.
December 29, 2025 at 6:37 AM
i realized that on monday last week i wore the "sunflower" restaurant shirt i got the last time we had dinner together, in november last year. that was shortly after she finished her breast cancer treatment. but then soon after she found out it had migrated to her brain.