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Mark P. Lythgoe

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Reposted by: Mark P. Lythgoe

yukselurun.bsky.social
Early-onset cancers (<50 yrs) are rising globally, linked to early-life exposures like diet, lifestyle, & microbiome changes. Awareness & dedicated studies are crucial. #Cancer #EarlyOnsetCancer #Oncology @oncoalert.bsky.social
rdcu.be/d49Ol
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by Mark P. Lythgoe

drmarklythgoe.bsky.social
Our thoughts on the evolving #posology of #Immunecheckpointinhibitors in
@trends in #Cancer

www.cell.com/trends/cance...
The evolving posology and administration of immune checkpoint inhibitors: subcutaneous formulations
Immune checkpoint inhibitors (ICIs) have transformed cancer care. Recently, atezolizumab gained its first global approval in a subcutaneous (SC) formulation by the UK medicines regulator, being notable as the first time an FDA- and/or European Medicines Agency (EMA)-approved ICI has been licensed via this administration route. Here, we discuss this approval, other SC ICIs in development, and the benefits and challenges of this administration route, including potential implications for patient care.
www.cell.com
3

by Mark P. Lythgoe

drmarklythgoe.bsky.social
#Subcutaneous nivolumab approved by
@fda.gov across all indications - follows approval of SC atezolizumab in Sept 2024.

Will this be the preferred route of administration or will this suppress the development of new biosimilars?

@oncodaily.bsky.social @hemoncwarner.bsky.social
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by Mark P. Lythgoe

drmarklythgoe.bsky.social
Wow #bluesky added to #altrimetric scores!
2

by Simon Hix — Reposted by: Mark P. Lythgoe, Franz Essl, John Newman , and 9 more

bsky.app
Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪
altmetric.com
Altmetric @altmetric.com · Dec 3
There are already many articles for which there is more attention on Bluesky than on other comparable micro-blogging sites, meaning the academic community and the general public have clearly adopted Bluesky as one of its core places to disseminate and discuss new research.

A Place of Joy.
‘A place of joy’: why scientists are joining the rush to Bluesky Researchers say the social-media platform — an alternative to X — offers more control over the content they see and the people they engage with.: https://www.nature.com/articles/d41586-024-03784-6
460 5.1K 30K

Reposted by: Mark P. Lythgoe, Arash Rashidian, Franz Essl , and 17 more

altmetric.com
There are already many articles for which there is more attention on Bluesky than on other comparable micro-blogging sites, meaning the academic community and the general public have clearly adopted Bluesky as one of its core places to disseminate and discuss new research.

A Place of Joy.
‘A place of joy’: why scientists are joining the rush to Bluesky Researchers say the social-media platform — an alternative to X — offers more control over the content they see and the people they engage with.: https://www.nature.com/articles/d41586-024-03784-6
49 670 2.5K

by Mark P. Lythgoe

drmarklythgoe.bsky.social
Hugely interesting paper in
#nature
about #SONIA trial challenging frontline CDK4/6 use in #breastcancer - does this have implications for practice today?

www.nature.com/articles/s41...
Early versus deferred use of CDK4/6 inhibitors in advanced breast cancer - Nature
The phase 3 SONIA trial challenges the benefits of using cyclin-dependent kinase 4 and 6 inhibitors as a first-line compared with second-line treatment.
www.nature.com
1 3

Reposted by: Mark P. Lythgoe

n8pennell.bsky.social
How to Keep Up With Molecular Testing and Targeted Therapies in Lung Cancer | JCO Oncology Practice ascopubs.org/doi/10.1200/... #LCSM
How to Keep Up With Molecular Testing and Targeted Therapies in Lung Cancer | JCO Oncology Practice
Until the early 2000s, advanced or metastatic non–small cell lung cancer (NSCLC) was treated as a single disease with all histologic subtypes treated alike with standard chemotherapy agents. Over the ...
ascopubs.org
8 22

Reposted by: Mark P. Lythgoe

bmj.com
The World Health Organization notes 300 essential drugs are now in shortage.

What's behind the problems and what are countries doing about it?
www.bmj.com/content/387/...
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References

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