Lightnews — Scholar-powered news

Suzie Cro @suziecro.bsky.social · Sep 1

Are estimands being correctly used?
A new review of protocols led by Timothy Clark shows many incorrectly defined estimand attributes. See the top areas for improvement & full results here:
trialsjournal.biomedcentral.com/articles/10.... #Trials

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Beatriz Goulão @beatrizgoulao.bsky.social · Jul 29

Another great post fr @chrischirp.bsky.social focusing on @nihr.bsky.social HSDR funding to improve patient's and staff's experiences. Very proud to be involved, & to have the opportunity to work w and learn fr fab colleagues including @instagraham.bsky.social @katiejsheehan.bsky.social

Prof Christina Pagel @chrischirp.bsky.social · Jul 29

The NHS & Social Care are struggling.

Behind the scenes, researchers are working on practical ways to make care better.

From ambulance handovers to teen mental health, I've written about the quiet research funded by @nihr.bsky.social HSDR.

christinapagel.substack.com/p/the-resear...

The research trying to improve health and social care services

How UK health research funding is tackling the front-line problems we face — from GP access to mental health and care homes

christinapagel.substack.com

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Prof Christina Pagel @chrischirp.bsky.social · Jul 29

The NHS & Social Care are struggling.

Behind the scenes, researchers are working on practical ways to make care better.

From ambulance handovers to teen mental health, I've written about the quiet research funded by @nihr.bsky.social HSDR.

christinapagel.substack.com/p/the-resear...

The research trying to improve health and social care services

How UK health research funding is tackling the front-line problems we face — from GP access to mental health and care homes

christinapagel.substack.com

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Andrew Heiss @andrew.heiss.phd · Mar 20

I’ve long used FiveThirtyEight’s interactive “Hack Your Way To Scientific Glory” to illustrate the idea of p-hacking when I teach statistics. But ABC/Disney killed the site earlier this month :(

So I made my own with #rstats and Observable and #QuartoPub ! stats.andrewheiss.com/hack-your-way/

Screenshot of the linked Quarto website, with input checkboxes to change different conditions for a regression model that predicts economic performance based on US political party, with a reported p-value

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Beatriz Goulão @beatrizgoulao.bsky.social · Jun 11

Always a good conference to follow for innovative trial designs in the context of critical care 👇🏻 #CCR25

Marion Campbell @marionkcampbell.bsky.social · Jun 11

#CCR25 … here we go! Three days of deep discussion of the top trials in critical care. If you are not in the room, do connect via livestream - see criticalcarereviews.com

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UK CTU Network @ukcrc-ctu.org.uk · Jun 17

The CONSORT 2025 Statement is here. Essential reading for those involved in the reporting & reviewing of randomized trials.

We're proud to see so many #UKCTUNetwork units & individual researchers contributing to this crucial update!

🔗 tinyurl.com/yc3cbh33

#CONSORT2025 #ResearchTransparency

CONSORT 2025 Statement

This Special Communication introduces the updated Consolidated Standards of Reporting Trials (CONSORT) 2025 statement, which includes substantive and structural changes to account for recent methodolo...

jamanetwork.com

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Marion Campbell @marionkcampbell.bsky.social · Jun 11

So true re innovative designs at #CCR25 … first trial (the TARGET Protein trial) was a multi-period cluster crossover design! For full details see the (just published) manuscript ja.ma/4kuYRxv

Beatriz Goulão @beatrizgoulao.bsky.social · Jun 11

Always a good conference to follow for innovative trial designs in the context of critical care 👇🏻 #CCR25

Marion Campbell @marionkcampbell.bsky.social · Jun 11

#CCR25 … here we go! Three days of deep discussion of the top trials in critical care. If you are not in the room, do connect via livestream - see criticalcarereviews.com

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Brennan Kahan @brennankahan.bsky.social · May 29

New 3-post for a research/senior research fellow to work on adaptive longitudinal cluster randomised trials in Melbourne.

Interesting work with a great research group.

careers.pageuppeople.com/513/cw/en/jo...

Job Search

careers.pageuppeople.com

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StatsCI @statsci.bsky.social · May 15

Missed the 1st PPI for Statistician Community of Practice webinar on the organising teams PPI? including our @suziecro.bsky.social @rachpips.bsky.social & Laura Gray Jonny Broomfield @beatrizgoulao.bsky.social @kararoyle.bsky.social check out the recording: leicesterbrc.nihr.ac.uk/ppismart/ppi...

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Beatriz Goulão @beatrizgoulao.bsky.social · Apr 14

Really enjoyed reading this commentary by @kevinweinfurt.bsky.social which proposes strategies to enhance understanding of meaningful changes in #clinicaltrials

kevinweinfurt.bsky.social @kevinweinfurt.bsky.social · Apr 9

New publication commenting on approaches to understand the meaningfulness of treatment effects on endpoints based on clinical outcome assessments (COAs). Sorting out "between-group difference," "meaningful within-group change," and more.

rdcu.be/eg5x7

1/5 Summary to follow...

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kevinweinfurt.bsky.social @kevinweinfurt.bsky.social · Apr 9

New publication commenting on approaches to understand the meaningfulness of treatment effects on endpoints based on clinical outcome assessments (COAs). Sorting out "between-group difference," "meaningful within-group change," and more.

rdcu.be/eg5x7

1/5 Summary to follow...

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Beatriz Goulão @beatrizgoulao.bsky.social · Apr 1

I've heard lots of Dune statistical analogies were taking place! 😂

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Beatriz Goulão @beatrizgoulao.bsky.social · Mar 21

So cool, thank you for sharing!

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Jan R. Boehnke @jrboehnke.bsky.social · Mar 20

The Leverhulme Research Centre for Forensic Science’s podcase "Inside Forensic Science" has been shortlisted at the True Crime Awards, category "Outstanding Indie Podcast" 🎉

You can find out more here:
www.dundee.ac.uk/projects/ins...

#DundeeUni #Saidheans

Inside Forensic Science podcast

The story of a crime scene investigation through the eyes of forensic scientists.

www.dundee.ac.uk

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Beatriz Goulão @beatrizgoulao.bsky.social · Mar 13

Thank you 😊

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Royal Statistical Society @royalstatsoc.bsky.social · Mar 3

📣 Journalists

You have until next Weds to submit your entry for our Statistical Excellence Awards, with categories in investigative, data vis and explaining the facts

Also with a category for the contribution of scientists to the media

Enter now ➡️ rss.org.uk/training-eve...

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Beatriz Goulão @beatrizgoulao.bsky.social · Mar 11

In a world where we often despair with hopelessness, @chrischirp.bsky.social work is essential. Great ideas about making a difference below 👇🏻👏
open.substack.com/pub/christin...

Eight things scientists can do right now to stand up to the Trump administration’s attacks on research, public health, and the environment

A guest post by Dr Anne Toomey, author of the book "Science with Impact: How to Engage People, Change Practice, and Influence Policy".

open.substack.com

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Beatriz Goulão @beatrizgoulao.bsky.social · Mar 10

Morning in the Caledonian Sleeper train (from Aberdeen to London). Absolutely stunning ❤️

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Beatriz Goulão @beatrizgoulao.bsky.social · Mar 10

@jclinepi.bsky.social

Journal of Clinical Epidemiology @jclinepi.bsky.social · Mar 9

Measuring the environmental impact of health interventions in randomised controlled trials – a scoping review - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Measuring the environmental impact of health interventions in randomised controlled trials – a scoping review

Healthcare accounts for 4% of the overall greenhouse gas emissions worldwide. Reducing carbon emissions is a key strategic aim for health systems in multiple countries. To achieve this, environmental ...

www.jclinepi.com

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Prof Christina Pagel @chrischirp.bsky.social · Feb 24

🧵Delighted to share a new guest post by Dr Anne Toomey on **8 things scientists can do right now to stand up for science in the US**

Thread of her *evidence-based* actions follows, whole post here
christinapagel.substack.com/p/eight-thin... 1/11

Eight things scientists can do right now to stand up to the Trump administration’s attacks on research, public health, and the environment

A guest post by Dr Anne Toomey, author of the book "Science with Impact: How to Engage People, Change Practice, and Influence Policy".

christinapagel.substack.com

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Peter Tennant @pwgtennant.bsky.social · Feb 24

"Selection bias: where are we now?"

Incredibly excited to announce the next Causal Inference Interest Group seminar with @haidonglu.bsky.social will take place on 10th March 2025 at 3pm GMT (11am EDT).

Don't miss this one!

Register at: turing-uk.zoom.us/meeting/regi...

#EpiSky #CausalSky #CIIG

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Beatriz Goulão @beatrizgoulao.bsky.social · Feb 21

Congratulations, super star!!! So happy for you 😍

Rachel Phillips @rachpips.bsky.social · Feb 20

🔈Announcing a series of webinars showcasing our 2024 Trials Adverse Event Special Series.

Over the course of 2025 we have a range of talks lined up covering trial conduct, analysis, reporting, and public involvement.

Please register your interest here: forms.microsoft.com/e/qqNgLTP651

Microsoft Forms

forms.microsoft.com

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Marion Campbell @marionkcampbell.bsky.social · Feb 17

I’ve seen a number of trial applications in development over recent weeks with lots of discussion about appropriate sample size calculations. A good time to remind everyone about the perils of the “sample size samba” 1/8
#MethodologyMonday #111

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Journal of Clinical Epidemiology @jclinepi.bsky.social · Feb 12

Endpoint assessment via routinely collected data generates estimates comparable to randomized controlled trial data: analysis of a cluster-randomized trial on fall injury prevention - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Endpoint assessment via routinely collected data generates estimates comparable to randomized controlled trial data: analysis of a cluster-randomized trial on fall injury prevention

Routinely collected data (RCD) from healthcare claims and encounters are increasingly used for outcomes in randomized trials; however, methods for estimating the validity and relative precision of RCD...

www.jclinepi.com

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Katie Gillies @katiegillies.bsky.social · Feb 12

Currently low response rates from CTU Directors (n=5), Programmers/Data Managers (n=0), & QA Managers (n=3) working in clinical trials. We need to know what these groups think the challenges are for greener trials.

forms.office.com/e/fkeLD8HbMA

Please complete &RT

@ukctunetwork.bsky.social

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Marion Campbell @marionkcampbell.bsky.social · Feb 3

Ensuring a trial has an independent data monitoring committee (DMC) is crucial to the safety and oversight of clinical trials. But a question this week was whether there is ever a scenario where a DMC might legitimately be deemed not to be essential 1/8
#MethodologyMonday #110

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Simon Gates @sim0ngates.bsky.social · Feb 1

For no particular reason, if any statisticians based in the US might be looking for a job in the UK, we'll be advertising a couple in the near future.
(CRCTU, University of Birmingham)

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American Statistical Association History of Statistics @hos-asa.bsky.social · Jan 28

#OTD 28 Jan 1809 Louis-Dominique-Jules Gavarret b (d 30 Aug 1890) An early proponent of the 'statistical method' in medicine, his 1840 book 'Principes de Statistique Médicale' was among the first to describe statistical principles for rigorous clinical trial conduct. /10 🧵

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