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fronzeslab.bsky.social
Rémi Fronzes
@fronzeslab.bsky.social
3.1K followers 3.7K following 770 posts
🔬 CNRS Research Director, Bordeaux | Structural biologist & microbiologist 🚴‍♂️ Cyclist (mostly Velotaf) & runner (just for fun) ⛰️ Mountain & nature lover 🎓 UCL/Birkbeck & Institut Pasteur alumnus 🔬 fronzeslab.cnrs.fr #cryoEM #cryoET #microsky
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fronzeslab.bsky.social
Rémi Fronzes @fronzeslab.bsky.social · Jan 26
We are very pleased to share our latest preprint on the architecture of the membrane complex of the type 7 secretion system involved in bacterial competition in B. subtilis.
#CryoEM #microsky
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Reposted by Rémi Fronzes
asaflevylab.bsky.social
Asaf Levy @asaflevylab.bsky.social · 17d
A recent cool preprint by John Whitney's lab on a new family of antibacterial proteins secreted by Gram-positive bacteria that enter and kill a broad spectrum of bacteria. Cell entry is receptor-independent and relies on cleavage by a co-secreted protease and the PMF.
www.biorxiv.org/content/10.1...
Proteolytically activated antibacterial toxins inhibit the growth of diverse Gram-positive bacteria
Many species of bacteria produce small-molecule antibiotics that enter and kill a wide range of competitor microbes. However, diffusible antibacterial proteins that share this broad-spectrum activity ...
www.biorxiv.org
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fronzeslab.bsky.social
Rémi Fronzes @fronzeslab.bsky.social · 1d
20 years of hard work by the Waksman group in London.
So happy that I could modestly contribute to this scientific adventure.
embojournal.org
The EMBO Journal @embojournal.org · 2d
Type IV secretion systems: from structures to mechanisms
Kévin Macé and colleagues summarize recent structural insights into the assembly and function of bacterial type IV secretion systems
www.embopress.org/doi/full/10....
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Reposted by Rémi Fronzes
cascaleslab.bsky.social
Cascales Lab @cascaleslab.bsky.social · 2d
Open position to work on Type IX secretion (#T9SS) in our lab, in collaboration withe the group of Eric Reynolds at the Dental School of the University of Melbourne. Please spread the word, and forward to anyone potentially interested ! Apply here:
emploi.cnrs.fr/Offres/Docto...
Portail Emploi CNRS - Offre d'emploi - Thèse en Microbiologie-Biochimie (H/F)
emploi.cnrs.fr
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Reposted by Rémi Fronzes
pilhoferlab.bsky.social
Pilhofer Lab 🦠❄️🔬 @pilhoferlab.bsky.social · 2d
🧐Checkout our preprint revealing the stepwise firing💥 mechanism of a Contractile Injection System @xujwet.bsky.social[email protected] trapped the complex by structure-guided engineering🧪 in multiple intermediate states and imaged them by multimodal #cryoEM❄️🔬
www.biorxiv.org/content/10.1...
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fronzeslab.bsky.social
Rémi Fronzes @fronzeslab.bsky.social · 3d
scary !!!
carlquintanilla.bsky.social
Carl Quintanilla @carlquintanilla.bsky.social · 3d
#WarRavagedPortland
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Reposted by Rémi Fronzes
gdrimabio.bsky.social
GdR ImaBio @gdrimabio.bsky.social · 3d
Let's explore the #Mifobio2025 programme !
👉 Focus on the seminars

✨ We are delighted to welcome Professor Ralf JUNGMANN
@lmumuenchen.bsky.social

🎤Talk -“From DNA Nanotechnology to biomedical insight : Towards single-molecule spatial omics”

👉 imabio-cnrs.fr
#GDRImaBio @mpibiochem.bsky.social
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Reposted by Rémi Fronzes
proftracypalmer.bsky.social
Tracy Palmer @proftracypalmer.bsky.social · 6d
Check it out! A proper team effort from past and present group members and a great collaboration with @sergemostowylab.bsky.social
biorxiv-microbiol.bsky.social
bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 6d
The Staphylococcus aureus LXG-domain toxins EsxX and SAR0287 do not promote virulence in a zebrafish larval infection model https://www.biorxiv.org/content/10.1101/2025.10.04.680436v1
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fronzeslab.bsky.social
Rémi Fronzes @fronzeslab.bsky.social · 7d
late to the party (Not really into series)
Pretty good stuff. Very funny.
Regarder Slow Horses - Apple TV+
Cette fiction d'espionnage ingénieuse suit une équipe dysfonctionnelle d'agents du MI5 - et leur odieux patron, le célèbre Jackson Lamb - qui naviguen…
tv.apple.com
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fronzeslab.bsky.social
Rémi Fronzes @fronzeslab.bsky.social · 7d
When (We) the People start to uncover the real nature of these clowns
En Argentine, Javier Milei enchaîne les revers avant les élections législatives de mi-mandat
Le Sénat a définitivement rejeté le veto présidentiel portant sur une revalorisation du budget des universités et des centres pédiatriques, alors que des alliés politiques commencent à tourner le dos ...
www.lemonde.fr
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fronzeslab.bsky.social
Rémi Fronzes @fronzeslab.bsky.social · 9d
enjoy !
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Reposted by Rémi Fronzes
helgethomas.bsky.social
Helge Thomas 🌻 @helgethomas.bsky.social · Aug 11
Imagine all cars were electric, and then one Volkswagen engineer comes up with another idea …

#EMobility
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fronzeslab.bsky.social
Rémi Fronzes @fronzeslab.bsky.social · 9d
C'est vrai que ce sont les 'Mamadous' qui ont foutu l'hôpital public à terre... Bizarre, pour moi les coupables sont ailleurs... sous les ors de la République.
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fronzeslab.bsky.social
Rémi Fronzes @fronzeslab.bsky.social · 9d
🤢
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fronzeslab.bsky.social
Rémi Fronzes @fronzeslab.bsky.social · 9d
These people claim they are 'real' Christians. I am no specialist, but I thought the Bible was about welcoming the stranger, caring for the poor, and healing the sick... How do they reconcile their hatred for the majority of humans with their faith? That's a mystery.
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Reposted by Rémi Fronzes
newscientist.com
New Scientist @newscientist.com · 9d
Acclaimed conservationist and chimpanzee expert Jane Goodall has died, leaving behind a legacy of empathy for primates and the natural world
Jane Goodall, dogged advocate for the natural world, has died aged 91
www.newscientist.com
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Reposted by Rémi Fronzes
valmasdel.bsky.social
Valérie Masson-Delmotte @valmasdel.bsky.social · 9d
"What you do makes a difference, and you have to decide what kind of difference you want to make"
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fronzeslab.bsky.social
Rémi Fronzes @fronzeslab.bsky.social · 9d
despicable
atrupar.com
Aaron Rupar @atrupar.com · 9d
Vance: "If you're an American citizen & you've been to the hospital in the last few years, you've probably noticed wait times are especially large & very often somebody who's there in the ER is an illegal alien. Why do those people get healthcare benefits at hospitals paid for by American citizens?"
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Reposted by Rémi Fronzes
laurentterradot.bsky.social
Terradot lab @laurentterradot.bsky.social · 13d
Still Time to read this new study form Mathilde Guzzo’s Lab post doc @cjresearch.bsky.social with our structural contribution !
mguzzo.bsky.social
Guzzo lab - Lyon @mguzzo.bsky.social · Aug 24
Check out the first preprint from our lab describing a direct molecular cross-talk between (p)ppGpp and c-di-GMP nucleotide messengers! Great work from first-author Corentin Jaboulay who was a postdoc in our lab, and great collaborations! @mmsb-lyon.bsky.social @cnrsbiologie.bsky.social
biorxiv-microbiol.bsky.social
bioRxiv Microbiology @biorxiv-microbiol.bsky.social · Aug 24
Cross-regulation of (p)ppGpp and c-di-GMP pathways controls a cell-cycle transition https://www.biorxiv.org/content/10.1101/2025.08.22.671821v1
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Reposted by Rémi Fronzes
cascaleslab.bsky.social
Cascales Lab @cascaleslab.bsky.social · 13d
We will have soon an Open position for a PhD thesis position to work on bacterial secretion systems !

Stay tuned !!
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Reposted by Rémi Fronzes
cnrs.fr
CNRS @cnrs.fr · 15d
Global warming is not a “con job.” It is a fact.

In the face of Donald Trump’s new denial of climate change, CNRS scientists have reacted by pointing to the facts and levers for action to halt this planetary crisis.
Global warming is not a “con job.” It is a fact.
In the face of Donald Trump’s new denial of climate change, CNRS scientists have reacted by pointing to the facts and levers for action to
www.cnrs.fr
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fronzeslab.bsky.social
Rémi Fronzes @fronzeslab.bsky.social · 16d
Le jeudi est le pire jour de la semaine.
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fronzeslab.bsky.social
Rémi Fronzes @fronzeslab.bsky.social · 17d
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fronzeslab.bsky.social
Rémi Fronzes @fronzeslab.bsky.social · 18d
As simple as asking Grok or ChatGPT.
We, the scientific community, should have thought about it !!! Such geniuses !!!
Reposted by Rémi Fronzes
legorafi.bsky.social
Le Gorafi @legorafi.bsky.social · 22d
Une université américaine lance une enquête sur un professeur d’archéologie suspecté d'être un « antifa » www.legorafi.fr/2025/09/19/u...
Une université américaine lance une enquête sur un professeur d’archéologie suspecté d’être un « antifa »
L’université américaine Marshall a annoncé lancer une enquête approfondie concernant les activités suspectes de l’un de ses enseignants, aujourd’hui décédé, une renommée du monde de l’archéologie, le ...
www.legorafi.fr
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elife.bsky.social
eLife @elife.bsky.social · 20d
A new #CryoET study shows that the protein ZapD helps organise FtsZ filaments into stable ring-like structures in building bacterial division machinery.
buff.ly/saLPqJM
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