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Federico Gueli @siamosolocani.bsky.social · 6h

Denial is always tricky, because it fails to explain the origin of a a behaviour, event, process, phenomenon.
It fails to give causes and effects.
So human, so old, so past.

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Federico Gueli @siamosolocani.bsky.social · 13h

Thanks Mike

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Reposted by Federico Gueli

Mike Honey @mikehoney.bsky.social · 1d

Huge thanks to all the dedicated variant hunters who persevere with their crucial work away from the limelight, especially to Federico Gueli for his tips on new lineages, eg
bsky.app/profile/siam...
🧵

Federico Gueli @siamosolocani.bsky.social · 1d

Quick Sars cov2 variant update.
XFG.17.2.1 ( 219S 679R) is the fastest then there PE.1.4/PE.1.7 but still an Oceania only lineage.
After them some new designations are to watch XFG.10.4 first XFG designated with 435S
PQ.2.8.1 has S:H445P.

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Federico Gueli @siamosolocani.bsky.social · 13h

a bunch of new XFG designations spanning from 845S to 679R and 704L. B ut the most interesting one is PL.6 a LF.7.1.10 (445P) that got 478T and S:T500A, becoming the ifrst lineage with S:T500A to get a designation

Federico Gueli @siamosolocani.bsky.social · 1d

Quick Sars cov2 variant update.
XFG.17.2.1 ( 219S 679R) is the fastest then there PE.1.4/PE.1.7 but still an Oceania only lineage.
After them some new designations are to watch XFG.10.4 first XFG designated with 435S
PQ.2.8.1 has S:H445P.

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Federico Gueli @siamosolocani.bsky.social · 1d

i would say tha on XFG backbone 679R is the most convergent beneficial mutation right now

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Federico Gueli @siamosolocani.bsky.social · 1d

@snpoehlm.bsky.social

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Reposted by Federico Gueli

Josette Schoenmakers @josetteschoenma.bsky.social · 2d

After 3 months, South Africa has uploaded another BA.3.2.2.

It has 3 mutations in common with the Australian samples, which we haven't seen outside of Australia before. T1195C, C2592T and T6856C. So, it probably migrated after it gained those.

It gained some extra mutations after that.

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Reposted by Federico Gueli

Mike Honey @mikehoney.bsky.social · 2d

Here's the latest variant picture with a global scope, to late September.

XFG.* "Stratus" was higher at 73%.

NB.1.8.1 "Nimbus" fell to 18%.

#COVID19 #SARSCoV2 #Global #NB_1_8_1 #Nimbus #XFG #Stratus
🧵

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Reposted by Federico Gueli

Mike Honey @mikehoney.bsky.social · 1d

The trickle of BA.3.2.2 samples from Western Australia has continued.

While the frequencies of this variant are still quite low, it’s ongoing spread (likely to many thousands of infections by now) gives it every opportunity to acquire the mutations it needs to succeed.

#COVID19 #Australia
🧵

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Federico Gueli @siamosolocani.bsky.social · 1d

Quick Sars cov2 variant update.
XFG.17.2.1 ( 219S 679R) is the fastest then there PE.1.4/PE.1.7 but still an Oceania only lineage.
After them some new designations are to watch XFG.10.4 first XFG designated with 435S
PQ.2.8.1 has S:H445P.

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Reposted by Federico Gueli

Ryan Hisner @ryanhisner.bsky.social · 17d

Attenuation of the SARS-2 furin-cleavage site (FCS) continues apace. It's beginning to look as if some form of FCS-weakening mutation might well become fixed in the near future. Collectively, they are at ~12% globally—a totally unprecedented level—& rising quickly. 1/4

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Reposted by Federico Gueli

Mitì Vigliero @mitivigliero.bsky.social · 3d

CVD

Caso Almasri, no della Camera al processo per Nordio, Piantedosi e Mantovano

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Reposted by Federico Gueli

thetranscendedman @atranscendedman.bsky.social · 6d

Researchers at HSE University and the Russian Academy of Sciences found a 2022 COVID sample from an HIV+ woman in Kaluga that evolved for about two years inside her body.

Clues suggest the virus persisted in her gut before reappearing in her airways.

www.frontiersin.org/journals/cel...

Frontiers | A highly divergent sample from a nearly extinct SARS-CoV-2 lineage in a patient with long-term COVID-19

BackgroundAlthough COVID-19 is primarily an acute disease, there are cases of persistent infection, primarily in immunocompromised patients. It is hypothesiz...

www.frontiersin.org

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Reposted by Federico Gueli

Otafuku3 @otafuku3.bsky.social · 6d

@doropfan.bsky.social

筆者欄すごい。HisnerさんやGueliさんも。

thetranscendedman @atranscendedman.bsky.social · 6d

Researchers at HSE University and the Russian Academy of Sciences found a 2022 COVID sample from an HIV+ woman in Kaluga that evolved for about two years inside her body.

Clues suggest the virus persisted in her gut before reappearing in her airways.

www.frontiersin.org/journals/cel...

Frontiers | A highly divergent sample from a nearly extinct SARS-CoV-2 lineage in a patient with long-term COVID-19

BackgroundAlthough COVID-19 is primarily an acute disease, there are cases of persistent infection, primarily in immunocompromised patients. It is hypothesiz...

www.frontiersin.org

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Federico Gueli @siamosolocani.bsky.social · 5d

i think the wave is gone quite globally, probably still up in Indonesia, Western Europe, central and Southern South America

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Reposted by Federico Gueli

JPWeiland @jpweiland.bsky.social · 6d

Both emergency dept and wastewater data suggest a rapid decline in prevalence after a relatively modest summer peak. The lull in evolution continues... with no new fast variants close behind XFG.

That being said, we're still watching BA.3.2*

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Reposted by Federico Gueli

WHO @who.int · 8d

October is Breast Cancer Awareness Month

#BreastCancer is the most common cancer among women globally and represents approximately a quarter of all cancers that occur in women every year.
Breast cancer is highly curable if detected in its early stages and adequate treatment is provided.

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Federico Gueli @siamosolocani.bsky.social · 6d

with the last upload BA.3.2.2 represents 20% of samples collected in September in Western Australia. and 40% of the most recent ones. the tree shows no cluster involved so it is circulation
nextstrain.org/fetch/genome...

Caveat Oceania and Australia have their own epi dynamics

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Federico Gueli @siamosolocani.bsky.social · 6d

5 new samples : nextstrain.org/fetch/genome...

nextstrain.org

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Reposted by Federico Gueli

Tom Richardson Ph.D. @cascadetommy.bsky.social · 8d

At 0:20, three agents pick him up and slam him head first into the ground. There is no justification for this, they were trying to seriously injure him

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Federico Gueli @siamosolocani.bsky.social · 9d

this man refused to combat and he was jailed , today he entered Gaza and see how IDF treated him.
And be sure HAMAS would have done the same.

This is what men of peace suffer right now in the world.

x.com/itamar_green...

x.com

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Reposted by Federico Gueli

Stuart Neil @tetherin.bsky.social · 11d

www.aftenposten.no/meninger/deb...

Excellent and pithy rebuttal to Norway’s own Jonny-come-lately lab leak conspiracist who had developed a self-promotion cottage industry

La oss vende tilbake til bevisene for koronapandemiens opprinnelse

Jakten på pandemiens opprinnelse er for viktig til å bli avsporet av uvitenskapelige insinuasjoner.

www.aftenposten.no

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Reposted by Federico Gueli

Zach Hensel @zachhensel.bsky.social · 11d

Here’s an op-ed I wrote arguing to get back to a focus on the relevant facts when it comes to pandemic origins.

I wrote it in response to a debate that’s played out over the last year in Norwegian media that rarely slows down to check what’s true and false.

runestava.bsky.social @runestava.bsky.social · 11d

www.aftenposten.no/meninger/deb...

La oss vende tilbake til bevisene for koronapandemiens opprinnelse

Jakten på pandemiens opprinnelse er for viktig til å bli avsporet av uvitenskapelige insinuasjoner.

www.aftenposten.no

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Reposted by Federico Gueli

Rhys White @rhystwhite.bsky.social · 13d

🚨New paper out!

Why does Staphylococcus aureus ST1 dominate in BOTH people🧑‍⚕️ & cows🐄 in New Zealand… but rarely elsewhere?

Our latest comparative genomics study unpacks this mystery👇

📄 doi.org/10.1128/msph...

@asm.org

#AMR #Genomics #OneHealth

🖥️🧬💻
#AcademicSky
#MicroSky
🧪🧫🦠

Comparative genomics of endemic Staphylococcus aureus ST1 in New Zealand | mSphere

This study presents a comprehensive genomic analysis of S. aureus ST1, a lineage that is unusually dominant in both bovine and human populations in New Zealand. Leveraging New Zealand’s geographical i...

doi.org

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Reposted by Federico Gueli

Josette Schoenmakers @josetteschoenma.bsky.social · 17d

They seem to be rising both in wastewater in Perth/Western Australia, assuming the braun KP.3.x is PE.1.4.
bsky.app/profile/mike...

Mike Honey @mikehoney.bsky.social · 17d

Here’s the zoomed in view of their variant chart. BA.3.2.* rose sharply to 20.2% for the week ending 21-Sep-2025.

This is a small uptick from the prior week. BA.3.2.* grew the most in that week, from 7.9% to 20.2%, so is probably driving that change in momentum.
🧵

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