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Reposted by Alexey Veraksa

Perrimon Lab @perrimonlab.bsky.social · 15h

New paper: A Structure-Guided Kinase-Transcription Factor Interactome Atlas Reveals Docking Landscapes of the Kinome
Kim, Huang, Johnson, Yaron-Barir, Keven Wang, Cantley, Hu, Perrimon
bioRxiv 2025.10.10.681672; doi: doi.org/10.1101/2025...

A Structure-Guided Kinase-Transcription Factor Interactome Atlas Reveals Docking Landscapes of the Kinome

Protein kinases orchestrate cellular processes through phosphorylation, yet the structural basis for their specific binding partner interactions remains largely unmapped. Here, we present a structure-...

doi.org

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Alexey Veraksa @veraksa.bsky.social · 19h

Washed with elution buffer.

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Zsuzsa Kaldy @zsuzsakaldy.bsky.social · 2d

Faculty colleagues, please let your students know about our PhD program in Developmental and Brain Sciences at UMass Boston! Online info session coming up on 10/22 at 4.30 pm. Applications are due 12/1/25
www.umb.edu/academics/pr...
#devpsych #devsky #AcademicSky

Developmental & Brain Sciences PhD

UMass Boston's Developmental and Brain Sciences (DBS) PhD is a research-intensive program focused on understanding cognition, perception, and behavior when underlying neural and hormonal mechanisms ar...

www.umb.edu

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lacey @byelacey.bsky.social · 2d

it's that time of year, it's time to get your flu and covid booster shot unless you're from massachusetts then it's time for your flu and covid borcester shot

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Alexey Veraksa @veraksa.bsky.social · 3d

🤯

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Jarrett Byrnes @jebyrnes.bsky.social · 5d

That's right, folk! THREE TENURE TRACK JOBS IN BIOLOGY AT UMASS BOSTON! You might even be a good fit for more than one! Check 'em out! We'd love to have you!

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James Briscoe @jamesbriscoe.bsky.social · 5d

Very sad news, John Gurdon has died.

A developmental biologist's developmental biologist, Nobel prize winner

His work is the foundation of much of today's dev & stem cell bio.

An inspiration to many, including me. Always asking questions & wanting the answers

www.magd.cam.ac.uk/news/profess...

Professor Sir John Gurdon FRS (1933-2025) | Magdalene College

Magdalene College is deeply saddened to announce the death of Professor Sir John Gurdon FRS, who served as Master of the College from 1995 to 2002.

www.magd.cam.ac.uk

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Reposted by Alexey Veraksa

Janelia Research Campus @handle.invalid · 6d

🪰 A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system—a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the millions of connections between them.
🔗 https://hhmi.news/4o3EJnk

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Artologica aka Michele Banks @artologica.net · 6d

Ink paintings of mitosis in drosophila embryos were a little too niche for the art festival crowd, but I know my Blooskies will love them #sciart 🧪🪰 www.etsy.com/shop/artolog...

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Jeffrey J. Hall @mrjeffu.bsky.social · 24d

Video: a Japanese scientist was attacked by flies while giving the acceptance speech for his Ig Nobel Prize-winning research paper that proved painting Zebra-like stripes on cows led to a decrease in biting fly attacks.

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Max Heiman @heiman.bsky.social · 9d

Saturday morning, waiting for kid's soccer game, is a great time to indulge in the lowest form of humor:

LAB HAIKU!

1.
Does anyone know
whose PCR is in there?
BEEP. BEEP. BEEP. BEEP. BEEP.

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Joachim Goedhart @joachimgoedhart.bsky.social · 12d

Identification of optimal fluorophores for use in the Drosophila embryo by Timothy E Saunders and team: www.biorxiv.org/content/10.1...

Figure 1: Fluorophore intensity in the Drosophila blastoderm (n.c. 14). Comparison of (A) green and (B) red fluorescence intensity using the same intensity scaling in n.c. 14. The fluorescence signal did
not saturate. Shown are single imaging planes. Normalised histograms of fluorescence intensity for green (C) and red (D) fluorophores averaged across at least n=3 embryos per line. Scale bars = 20 μm

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Reposted by Alexey Veraksa

Craig Kaplan @triggerloop.bsky.social · 12d

I think the R01 is basically a non-starter at NIGMS now. Data from NIH Reporter for new and competing awards, comparing number of R01s issued relative to R35s (MIRA). This has major ramifications for basic science and basic science investigators that are not yet in the MIRA pool

Graph showing total R35+R01 awards issued by NIGMS from 2020 to 2025. R01 in black showing a steep decline. R35 showing an increase. Total awards in 2025 slightly up from 2024 but these years are lower than 2020-2023

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Alexey Veraksa @veraksa.bsky.social · 13d

That thought crossed my mind as well!

Alexey Veraksa @veraksa.bsky.social · 13d

Incredible sunset in Boston today

A view of colorful sunset in Boston, from a highway

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Drug Monkey @drugmonkey.bsky.social · 17d

This may be the most important paper ever published about NIH funded research.

www.science.org/doi/10.1126/...

What if NIH had been 40% smaller?

Replaying history with less NIH funding shows widespread impacts on drug-linked research

www.science.org

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Alexey Veraksa @veraksa.bsky.social · 17d

📢 We are hiring! Assistant Professor in Genetics position is open at @umassboston.bsky.social, to begin September 1, 2026. Apply and join our vibrant Biology department research program!
employmentopportunities.umb.edu/en-us/job/52...

Page Up - UMass Boston

employmentopportunities.umb.edu

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Developmental Biology @devbiol.bsky.social · 25d

CALL FOR PAPERS! 🧪

DB Special Issue highlights new insights into receptor tyrosine kinase signaling during development, with a focus on cell-cell interactions & signal transduction in the regulation of cell growth and division, differentiation & morphogenesis.

Submit here: tinyurl.com/RTKDevBio

Image showing a CALL FOR PAPERS for a special issue of Developmental Biology on "Receptor Tyrosine Kinase signaling in Development".

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Alexey Veraksa @veraksa.bsky.social · 22d

We determined the crystal structure of the DNA binding domain of the transcriptional repressor Capicua (CIC) in complex with its binding site. We explore how cancer-relevant mutations affect the binding, and how the binding specificity of the HMG box is aided by the C1 domain.

Alexey Veraksa @veraksa.bsky.social · 22d

I am excited to share that our collaborative project with the Daniel Dowling lab @umassboston.bsky.social and Gerardo Jimenez @ibmb-csic.bsky.social has been published!
authors.elsevier.com/c/1lnpp3SNvc... (gift link active for 50 days)

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Yogesh Goyal @goyallab.bsky.social · 24d

**POSTDOC POSITION** My lab (www.goyallab.org) at Northwestern and CZ Biohub Chicago looking for a postdoctoc in quantitative biology. We work on a range of topics, including single-cell cancer plasticity, modeling single-cell perturbations, theory, and stem-embryo models. contact via email. Pls RT

Goyal Lab

www.goyallab.org

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Shashank Shekhar lab @sshekhr.bsky.social · Aug 29

📢📢Hiring 2 Research Assistants & 2 Postdocs at Emory University in Atlanta to study cytoskeletal biophysics/biochemistry. Please RT.

RAs: great for recent bachelor's/master's in Physics/Bio/Chem/Biochem. Email CV and interests to [email protected].

More info: www.shekharlab.org

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Andreas Prokop @poppi62.bsky.social · Aug 25

Dear GenZ members of the #Drosophila community! You are needed to make cool fly research viral in your social media world! As a boomer I do not understand that sphere, but I can consult and contribute our enormous fund of outreach resources: droso4public.wordpress.com. Please, get in contact!