Angelica Ronald
@angelicaronald.bsky.social
Professor of Psychology and Genetics at University of Surrey
Reposted by Angelica Ronald
*New paper* showing that subclinical #hypomania @ 18:
-sig linked to 14 psychiatric/neurodev diagnoses
-Highest genetic correlations: ADHD, drug & alcohol misuse
-Highest enviro correlations: psychosis, anorexia & bipolar
acamh.onlinelibrary.wiley.com/doi/full/10....
@angelicaronald.bsky.social
-sig linked to 14 psychiatric/neurodev diagnoses
-Highest genetic correlations: ADHD, drug & alcohol misuse
-Highest enviro correlations: psychosis, anorexia & bipolar
acamh.onlinelibrary.wiley.com/doi/full/10....
@angelicaronald.bsky.social
September 22, 2025 at 1:48 PM
*New paper* showing that subclinical #hypomania @ 18:
-sig linked to 14 psychiatric/neurodev diagnoses
-Highest genetic correlations: ADHD, drug & alcohol misuse
-Highest enviro correlations: psychosis, anorexia & bipolar
acamh.onlinelibrary.wiley.com/doi/full/10....
@angelicaronald.bsky.social
-sig linked to 14 psychiatric/neurodev diagnoses
-Highest genetic correlations: ADHD, drug & alcohol misuse
-Highest enviro correlations: psychosis, anorexia & bipolar
acamh.onlinelibrary.wiley.com/doi/full/10....
@angelicaronald.bsky.social
Reposted by Angelica Ronald
Thanks to @uniofsurrey.bsky.social for funding this event.
London Genetics Network is a special interest group funded by the UK Genetic Society. If you are a researcher working in human genetics in London or the surrounding areas please email us to join the network: [email protected]
London Genetics Network is a special interest group funded by the UK Genetic Society. If you are a researcher working in human genetics in London or the surrounding areas please email us to join the network: [email protected]
July 14, 2025 at 11:46 AM
Thanks to @uniofsurrey.bsky.social for funding this event.
London Genetics Network is a special interest group funded by the UK Genetic Society. If you are a researcher working in human genetics in London or the surrounding areas please email us to join the network: [email protected]
London Genetics Network is a special interest group funded by the UK Genetic Society. If you are a researcher working in human genetics in London or the surrounding areas please email us to join the network: [email protected]
Reposted by Angelica Ronald
🔔 LGN Summer Lecture! Wed 16 Jul @ UCL Bloomsbury. @dr-appie.bsky.social (Amsterdam UMC) on “Genetic Architecture of a Social Construct”. ☕ 15:30 coffee | 16:00 talk | 🤝 17:00 networking. Members: check your email for the invite from the LGN mailing list.
July 14, 2025 at 11:46 AM
🔔 LGN Summer Lecture! Wed 16 Jul @ UCL Bloomsbury. @dr-appie.bsky.social (Amsterdam UMC) on “Genetic Architecture of a Social Construct”. ☕ 15:30 coffee | 16:00 talk | 🤝 17:00 networking. Members: check your email for the invite from the LGN mailing list.
Reposted by Angelica Ronald
Realizing the promise of genome-wide association studies for effector gene prediction www.nature.com/articles/s41...
June 12, 2025 at 10:25 AM
Realizing the promise of genome-wide association studies for effector gene prediction www.nature.com/articles/s41...
On 26th June check out the conference @acamh.bsky.social ‘Neurodiversity: Cutting-Edge Research, Evolving Perspectives, and Effective Innovations - 2025 Jack Tizard Memorial International Conference’. www.acamh.org/event/neurod...
Talks on new research and innovative approaches to #Neurodiversity
Talks on new research and innovative approaches to #Neurodiversity
Neurodiversity: Cutting-Edge Research, Evolving Perspectives, and Effective Innovations - 2025 Jack Tizard Memorial International Conference
'Neurodiversity: Cutting-Edge Research, Evolving Perspectives, and Effective Innovations' is the 2025 Jack Tizard Memorial Conference that brings together leading experts to explore neurodiversity res...
www.acamh.org
June 10, 2025 at 4:44 PM
On 26th June check out the conference @acamh.bsky.social ‘Neurodiversity: Cutting-Edge Research, Evolving Perspectives, and Effective Innovations - 2025 Jack Tizard Memorial International Conference’. www.acamh.org/event/neurod...
Talks on new research and innovative approaches to #Neurodiversity
Talks on new research and innovative approaches to #Neurodiversity
Reposted by Angelica Ronald
Researchers with ADHD discuss its peaks and valleys and how they structure their work lives to succeed
https://go.nature.com/3FitQh4
https://go.nature.com/3FitQh4
Scientists with ADHD speak up: when fire meets focus
Nature - Researchers with ADHD discuss its peaks and valleys and how they structure their work lives to succeed.
go.nature.com
May 31, 2025 at 1:13 PM
Researchers with ADHD discuss its peaks and valleys and how they structure their work lives to succeed
https://go.nature.com/3FitQh4
https://go.nature.com/3FitQh4
Reposted by Angelica Ronald
(9/9) It was a great pleasure working on this with Morgan Morgan, Ilan Libedinsky, Chloe Austerberry, Sander Begeer, @dr-appie.bsky.social, @angelicaronald.bsky.social and @tincatwin.bsky.social
May 31, 2025 at 9:21 AM
(9/9) It was a great pleasure working on this with Morgan Morgan, Ilan Libedinsky, Chloe Austerberry, Sander Begeer, @dr-appie.bsky.social, @angelicaronald.bsky.social and @tincatwin.bsky.social
Reposted by Angelica Ronald
(8/9) To conclude, due to inconsistent associations and limited generalizability, we underscore that the autism polygenic score does not have clinical utility and should only be applied for scientific purposes, with improvements needed for a deeper understanding of autism’s polygenic underpinnings
May 31, 2025 at 9:21 AM
(8/9) To conclude, due to inconsistent associations and limited generalizability, we underscore that the autism polygenic score does not have clinical utility and should only be applied for scientific purposes, with improvements needed for a deeper understanding of autism’s polygenic underpinnings
Reposted by Angelica Ronald
(7/9) We show that the autism polygenic score, as a standalone variable associates consistently with autism diagnostic status but is unable to capture the spectrum’s complex phenotypical and etiological differences and its genetic overlap with other traits and conditions.
May 31, 2025 at 9:21 AM
(7/9) We show that the autism polygenic score, as a standalone variable associates consistently with autism diagnostic status but is unable to capture the spectrum’s complex phenotypical and etiological differences and its genetic overlap with other traits and conditions.
Reposted by Angelica Ronald
(6/9) Associations with outcomes other than those mentioned above were inconclusive and effect sizes generally small (median r = 0.03). Hence, our results suggest the autism polygenic score may lack the statistical power to adequately capture polygenic effects.
May 31, 2025 at 9:21 AM
(6/9) Associations with outcomes other than those mentioned above were inconclusive and effect sizes generally small (median r = 0.03). Hence, our results suggest the autism polygenic score may lack the statistical power to adequately capture polygenic effects.
Reposted by Angelica Ronald
(5/9) Our systematic review also revealed evidence for associations with social behavior, depression, motor skills and physical activity, although these results show incongruency over samples.
May 31, 2025 at 9:21 AM
(5/9) Our systematic review also revealed evidence for associations with social behavior, depression, motor skills and physical activity, although these results show incongruency over samples.
Reposted by Angelica Ronald
(4/9) A meta-analysis of nine studies revealed strong evidence for an association between the autism polygenic score and autism diagnosis in independent cohorts (meta-analytic r = 0.158 (95% CI 0.067 – 0.249)), which supports the polygenic score’s specificity.
May 31, 2025 at 9:21 AM
(4/9) A meta-analysis of nine studies revealed strong evidence for an association between the autism polygenic score and autism diagnosis in independent cohorts (meta-analytic r = 0.158 (95% CI 0.067 – 0.249)), which supports the polygenic score’s specificity.
Reposted by Angelica Ronald
(3/9) The latest autism GWAS, led by @jakobgrove.bsky.social led to a wealth of studies assessing the relations between the autism PGS and various phenotypes. We included a total of 72 of these studies.
May 31, 2025 at 9:21 AM
(3/9) The latest autism GWAS, led by @jakobgrove.bsky.social led to a wealth of studies assessing the relations between the autism PGS and various phenotypes. We included a total of 72 of these studies.
Reposted by Angelica Ronald
(2/9) 🧬Genetic factors play a substantial role in the etiology of autism and its co-occurrence with other conditions and traits. We aimed to clarify the associations between the autism polygenic score and autism diagnosis, autistic traits, and related behavioral and neurobiological traits
May 31, 2025 at 9:21 AM
(2/9) 🧬Genetic factors play a substantial role in the etiology of autism and its co-occurrence with other conditions and traits. We aimed to clarify the associations between the autism polygenic score and autism diagnosis, autistic traits, and related behavioral and neurobiological traits
Reposted by Angelica Ronald
(1/9) 📣 OUT NOW! 📣
So excited to share that our systematic review and meta-analysis on the autism polygenic score is now published in JAACAP Open @jaacapjournals.bsky.social.
doi.org/10.1016/j.ja...
A (long) thread of our main findings ⤵️
So excited to share that our systematic review and meta-analysis on the autism polygenic score is now published in JAACAP Open @jaacapjournals.bsky.social.
doi.org/10.1016/j.ja...
A (long) thread of our main findings ⤵️
Redirecting
doi.org
May 31, 2025 at 9:21 AM
(1/9) 📣 OUT NOW! 📣
So excited to share that our systematic review and meta-analysis on the autism polygenic score is now published in JAACAP Open @jaacapjournals.bsky.social.
doi.org/10.1016/j.ja...
A (long) thread of our main findings ⤵️
So excited to share that our systematic review and meta-analysis on the autism polygenic score is now published in JAACAP Open @jaacapjournals.bsky.social.
doi.org/10.1016/j.ja...
A (long) thread of our main findings ⤵️
Reposted by Angelica Ronald
Excited to be in Milan for #eshg2025! If you’re interested in leading analysis of large, diverse cohorts with WGS and cellular genomic data in Australia, I’d be keen to chat - we’re looking to fill a variety of senior comp bio roles: populationgenomics.org.au/careers/ #eshg25
Careers - Centre for Population Genomics
populationgenomics.org.au
May 24, 2025 at 8:41 AM
Excited to be in Milan for #eshg2025! If you’re interested in leading analysis of large, diverse cohorts with WGS and cellular genomic data in Australia, I’d be keen to chat - we’re looking to fill a variety of senior comp bio roles: populationgenomics.org.au/careers/ #eshg25
Reposted by Angelica Ronald
Extremely excited to share the first effort of the Revived Genomics of Personality Consortium: A highly-powered, comprehensive GWAS of the Big Five personality traits in 1.14 million participants from 46 cohorts. www.biorxiv.org/content/10.1...
May 20, 2025 at 10:14 AM
Extremely excited to share the first effort of the Revived Genomics of Personality Consortium: A highly-powered, comprehensive GWAS of the Big Five personality traits in 1.14 million participants from 46 cohorts. www.biorxiv.org/content/10.1...
Reposted by Angelica Ronald
Want to learn more?
Read: 'Scientists discover the genes influencing when babies take their first steps'
www.surrey.ac.uk/news/scienti....
And 'Genes influencing when babies walk discovered, and these genes affect longer-term outcomes too'
communities.springernature.com/posts/genes-...
Read: 'Scientists discover the genes influencing when babies take their first steps'
www.surrey.ac.uk/news/scienti....
And 'Genes influencing when babies walk discovered, and these genes affect longer-term outcomes too'
communities.springernature.com/posts/genes-...
Scientists discover the genes that influence when babies start walking | University of Surrey
www.surrey.ac.uk
May 16, 2025 at 1:51 PM
Want to learn more?
Read: 'Scientists discover the genes influencing when babies take their first steps'
www.surrey.ac.uk/news/scienti....
And 'Genes influencing when babies walk discovered, and these genes affect longer-term outcomes too'
communities.springernature.com/posts/genes-...
Read: 'Scientists discover the genes influencing when babies take their first steps'
www.surrey.ac.uk/news/scienti....
And 'Genes influencing when babies walk discovered, and these genes affect longer-term outcomes too'
communities.springernature.com/posts/genes-...
Reposted by Angelica Ronald
📣Out now 📣
In a GWAS meta-analysis, @angelicaronald.bsky.social and colleagues identified 11 independent genome-wide significant loci associated with age at onset of walking.
www.nature.com/articles/s41...
In a GWAS meta-analysis, @angelicaronald.bsky.social and colleagues identified 11 independent genome-wide significant loci associated with age at onset of walking.
www.nature.com/articles/s41...
Genome-wide association meta-analysis of age at onset of walking in over 70,000 infants of European ancestry - Nature Human Behaviour
A genome-wide association study of age at onset of walking in over 70,000 infants found 11 significant loci. Age at onset of walking showed SNP heritability of 24%, a reliable polygenic score and gene...
www.nature.com
May 16, 2025 at 1:51 PM
📣Out now 📣
In a GWAS meta-analysis, @angelicaronald.bsky.social and colleagues identified 11 independent genome-wide significant loci associated with age at onset of walking.
www.nature.com/articles/s41...
In a GWAS meta-analysis, @angelicaronald.bsky.social and colleagues identified 11 independent genome-wide significant loci associated with age at onset of walking.
www.nature.com/articles/s41...
Reposted by Angelica Ronald
Very excited about this important piece of work with @angelicaronald.bsky.social characterising gene associations with age of walking onset. We also show using dHCP data that these are related to volume in key brain motor regions (like the deep grey nuclei and cerebellum) even as a newborn infant
Our gene discovery project on age at onset of walking is out today! Find the paper here www.nature.com/articles/s41... Huge thanks to the cohorts, collaborators & coauthors, in particular first author Dr Anna Gui 1/n
Genome-wide association meta-analysis of age at onset of walking in over 70,000 infants of European ancestry - Nature Human Behaviour
A genome-wide association study of age at onset of walking in over 70,000 infants found 11 significant loci. Age at onset of walking showed SNP heritability of 24%, a reliable polygenic score and gene...
www.nature.com
May 8, 2025 at 6:07 AM
Very excited about this important piece of work with @angelicaronald.bsky.social characterising gene associations with age of walking onset. We also show using dHCP data that these are related to volume in key brain motor regions (like the deep grey nuclei and cerebellum) even as a newborn infant
Reposted by Angelica Ronald
🧬 👶 🐥 How do genes influence when a baby takes their first step?
Our colleague Prof Angelica Ronald explores this question in a fascinating new blog post on Psychology Today. Drawing on her team’s recent publ in #NatureHumanBehaviour and #NatureGenetics.
www.psychologytoday.com/us/blog/surr...
Our colleague Prof Angelica Ronald explores this question in a fascinating new blog post on Psychology Today. Drawing on her team’s recent publ in #NatureHumanBehaviour and #NatureGenetics.
www.psychologytoday.com/us/blog/surr...
How Genes Influence the Timing of a Baby's First Step
The science behind motor milestones and learning to walk.
www.psychologytoday.com
May 7, 2025 at 4:37 PM
🧬 👶 🐥 How do genes influence when a baby takes their first step?
Our colleague Prof Angelica Ronald explores this question in a fascinating new blog post on Psychology Today. Drawing on her team’s recent publ in #NatureHumanBehaviour and #NatureGenetics.
www.psychologytoday.com/us/blog/surr...
Our colleague Prof Angelica Ronald explores this question in a fascinating new blog post on Psychology Today. Drawing on her team’s recent publ in #NatureHumanBehaviour and #NatureGenetics.
www.psychologytoday.com/us/blog/surr...
Reposted by Angelica Ronald
A genome-wide association study of age at onset of walking in over 70,000 infants found 11 significant loci. Age at onset of walking showed SNP heritability of 24%, a reliable polygenic score and genetic overlap with ADHD and brain phenotypes.
Genome-wide association meta-analysis of age at onset of walking in over 70,000 infants of European ancestry - Nature Human Behaviour
A genome-wide association study of age at onset of walking in over 70,000 infants found 11 significant loci. Age at onset of walking showed SNP heritability of 24%, a reliable polygenic score and genetic overlap with ADHD and brain phenotypes.
www.nature.com
May 7, 2025 at 5:41 PM
A genome-wide association study of age at onset of walking in over 70,000 infants found 11 significant loci. Age at onset of walking showed SNP heritability of 24%, a reliable polygenic score and genetic overlap with ADHD and brain phenotypes.
Reposted by Angelica Ronald
Scientists discover the genes influencing when babies take their first steps, study finds:
www.surrey.ac.uk/news/scienti...
@angelicaronald.bsky.social
www.surrey.ac.uk/news/scienti...
@angelicaronald.bsky.social
May 7, 2025 at 11:00 AM
Scientists discover the genes influencing when babies take their first steps, study finds:
www.surrey.ac.uk/news/scienti...
@angelicaronald.bsky.social
www.surrey.ac.uk/news/scienti...
@angelicaronald.bsky.social
Reposted by Angelica Ronald
Common DNA variants account for around a quarter of variability in age at onset of walking "...an important milestone that links genetically to a range of later health, educational & behavioural outcomes", according to new @nathumbehav.nature.com paper by @angelicaronald.bsky.social & colleagues.🧬🧪
Genome-wide association meta-analysis of age at onset of walking in over 70,000 infants of European ancestry - Nature Human Behaviour
A genome-wide association study of age at onset of walking in over 70,000 infants found 11 significant loci. Age at onset of walking showed SNP heritability of 24%, a reliable polygenic score and gene...
www.nature.com
May 7, 2025 at 3:51 PM
Common DNA variants account for around a quarter of variability in age at onset of walking "...an important milestone that links genetically to a range of later health, educational & behavioural outcomes", according to new @nathumbehav.nature.com paper by @angelicaronald.bsky.social & colleagues.🧬🧪
Our gene discovery project on age at onset of walking is out today! Find the paper here www.nature.com/articles/s41... Huge thanks to the cohorts, collaborators & coauthors, in particular first author Dr Anna Gui 1/n
Genome-wide association meta-analysis of age at onset of walking in over 70,000 infants of European ancestry - Nature Human Behaviour
A genome-wide association study of age at onset of walking in over 70,000 infants found 11 significant loci. Age at onset of walking showed SNP heritability of 24%, a reliable polygenic score and gene...
www.nature.com
May 7, 2025 at 4:30 PM
Our gene discovery project on age at onset of walking is out today! Find the paper here www.nature.com/articles/s41... Huge thanks to the cohorts, collaborators & coauthors, in particular first author Dr Anna Gui 1/n