All segments have to meet in the same host cell for complementation. The evolutionary benefit for this lifestyle is unclear.
All segments have to meet in the same host cell for complementation. The evolutionary benefit for this lifestyle is unclear.
ZIKV even uses them to acquire mitochondria from neighbouring uninfected cells!
ZIKV even uses them to acquire mitochondria from neighbouring uninfected cells!
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
#nanopores #smFRET #biomolecular #dynamics #singleMolecules
We’re looking for talented & ambitious new colleagues enthusiastic about biomolecular dynamics & single-molecule tech.
Please share broadly, thank you!🤝
schmid.chemie.unibas.ch
#nanopores #smFRET #biomolecular #dynamics #singleMolecules
We’re looking for talented & ambitious new colleagues enthusiastic about biomolecular dynamics & single-molecule tech.
Please share broadly, thank you!🤝
schmid.chemie.unibas.ch
Multiple positions across multiple groups @mrc-lms.bsky.social
Projects spanning germline demethylation, gene regulation, genome architecture in development & disease 👇👇
lms.mrc.ac.uk/work/vacanci...
🍿🥂🍪Signing up now will also ensure that we order enough drinks and snacks!
Sign up and come along. Everyone from Imperial/ MRC welcome! Limited spaces available, drinks and snacks included 🥂🧀
Registration and details here: www.eventbrite.co.uk/e/academic-w...
🍿🥂🍪Signing up now will also ensure that we order enough drinks and snacks!
HSV-1 actively rewires the human genome!
😲Look at how the host genome gets squeezed!!
HSV-1 actively rewires the human genome!
😲Look at how the host genome gets squeezed!!
www.nature.com/naturecareer...
www.nature.com/naturecareer...
Sign up and come along. Everyone from Imperial/ MRC welcome! Limited spaces available, drinks and snacks included 🥂🧀
Registration and details here: www.eventbrite.co.uk/e/academic-w...
Sign up and come along. Everyone from Imperial/ MRC welcome! Limited spaces available, drinks and snacks included 🥂🧀
Registration and details here: www.eventbrite.co.uk/e/academic-w...
Registration and details here: www.eventbrite.co.uk/e/academic-w...
It's so fluffy!! 😱
It's so fluffy!! 😱
Anyone interested in microsecond time-resolved cryo-EM should check out this paper:
www.nature.com/articles/s41...
Anyone interested in microsecond time-resolved cryo-EM should check out this paper:
www.nature.com/articles/s41...
Bacteriophage 29 (Phi29) uses RNA to help package genomic DNA 🤯. This so-called packaging RNA (pRNA) is an essential part of the packaging motor, which is part of the newly formed viral capsid.
Check out the pRNA (pink) in the beautiful structure:
www.science.org/doi/10.1126/...
Bacteriophage 29 (Phi29) uses RNA to help package genomic DNA 🤯. This so-called packaging RNA (pRNA) is an essential part of the packaging motor, which is part of the newly formed viral capsid.
Check out the pRNA (pink) in the beautiful structure:
www.science.org/doi/10.1126/...
The viral protein E6 regulates and directly interacts with hTERT and telomeric DNA.
The viral protein E6 regulates and directly interacts with hTERT and telomeric DNA.
Adeno-associated viruses (AAV) can only replicate if the same host cell is infected with a helper virus. AAV will remain in the host cell (latently infecting it) until a helper virus such as HSV or AdV comes along.
www.mdpi.com/1999-4915/12...
Adeno-associated viruses (AAV) can only replicate if the same host cell is infected with a helper virus. AAV will remain in the host cell (latently infecting it) until a helper virus such as HSV or AdV comes along.
www.mdpi.com/1999-4915/12...
HIV-1 and other retroviruses hijack cellular tRNA and use it as primer to initiate reverse transcription of their RNA genome.
They exploit the same tRNA terminal 3′-OH group used by the host for aminoacylation and peptidyl transfer.
HIV-1 and other retroviruses hijack cellular tRNA and use it as primer to initiate reverse transcription of their RNA genome.
They exploit the same tRNA terminal 3′-OH group used by the host for aminoacylation and peptidyl transfer.
In order to overcome the end replication problem, adenovirus DNA replication starts at a protein, rather than an RNA primer. The viral polymerase couples the first nucleotide (dCTP) to a serine on the terminal protein, which assures full replication by a jump-back mechanism. 😎
In order to overcome the end replication problem, adenovirus DNA replication starts at a protein, rather than an RNA primer. The viral polymerase couples the first nucleotide (dCTP) to a serine on the terminal protein, which assures full replication by a jump-back mechanism. 😎
https://go.nature.com/3FN700Z
www.sciencedirect.com/science/arti...
Image credit: viralzone.expasy.org/148
www.sciencedirect.com/science/arti...
Image credit: viralzone.expasy.org/148
⭐Coffee with Professor Lesley Cohen⭐
📅 When: Wednesday, 26 March 2025, 2-3.30 pm
📍 Where: 7th floor seminar room, LMS building, Hammersmith Campus, W12 0HS
💡Hear about what Imperial is doing to support women
Register here: forms.office.com/Pages/Respon...
Herpesvirus (HSV-1) assimilates the cellular motor kinesin-1 to travel within the cell. HSV-1 takes it up into the tegument to use it for future infection: www.nature.com/articles/s41...
Herpesvirus (HSV-1) assimilates the cellular motor kinesin-1 to travel within the cell. HSV-1 takes it up into the tegument to use it for future infection: www.nature.com/articles/s41...
With this 3-year postdoc position we want to enable scientists of Black heritage to learn & grow their experience.
Application deadline: 23 March
More info: www2.mrc-lmb.cam.ac.uk/recruitment/...
With this 3-year postdoc position we want to enable scientists of Black heritage to learn & grow their experience.
Application deadline: 23 March
More info: www2.mrc-lmb.cam.ac.uk/recruitment/...
Influenzaviruses chop off the 5'-mRNA cap of nascent host mRNA and use it for their own mRNA. This is called cap-snatching
Further reading: pmc.ncbi.nlm.nih.gov/articles/PMC...
Influenzaviruses chop off the 5'-mRNA cap of nascent host mRNA and use it for their own mRNA. This is called cap-snatching
Further reading: pmc.ncbi.nlm.nih.gov/articles/PMC...
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...