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Reposted by Bruce Verchere

Daniel Drucker @danieljdrucker.bsky.social · 9d

Novel insights into the molecular underpinnings of islet cell dysfunction in #T1D highlighting pathways that may be leveraged to preserve residual β-cell function and modulate α-cell activity @bcellorg.bsky.social www.jci.org/articles/vie...

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Reposted by Bruce Verchere

Daniel Drucker @danieljdrucker.bsky.social · 19d

The first GLP-1 medicine, twice daily exenatide was approved April 28 2005. Several decades later, the pace of innovation is expanding rapidly, encompassing new medicines and receptors, unique delivery options, and expanding therapeutic indications jamanetwork.com/journals/jam...

New Molecules and Indications for GLP-1 Medicines

This Perspective explores recent progress and future directions in glucagon-like peptide-1 medicines.

jamanetwork.com

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Bruce Verchere @bruceverchere.bsky.social · Aug 15

Congrats Meltem, that was an outstanding PhD defense!
Good luck in your next career steps!

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Bruce Verchere @bruceverchere.bsky.social · May 26

Congratulations and thanks to both Sarah Cs @sarahcrome.bsky.social @sarahcolpitts.bsky.social for including us as part of this lovely study, showing a role or ILC2s in islet graft survival.

Sarah Crome @sarahcrome.bsky.social · May 26

🧬 Excited to share our latest study now In Press: In this study led by rising star @sarahcolpitts.bsky.social, we show that IL-10⁺ #ILC2s prevent rejection and improve islet graft survival and function in humanized mouse models. Read more: doi.org/10.1016/j.aj... #Immunology #ImmunoSky #CellTherapy

Redirecting

doi.org

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Bruce Verchere @bruceverchere.bsky.social · May 14

How nice! Proud to be part of that group of colleagues and child health researchers. What a lovely recognition of recipients and reminder of Dr Hammond's leadership at @bcchresearch.bsky.social.

BCCHR ResDev (DM) @resdevbcch.bsky.social · May 14

Fabulous new wall art @bcchresearch.bsky.social celebrating winners of GL Hammond Lectureship over past decade (1/y).
🎉🎉Congrats to all including @mklevings.bsky.social
@wprobins.bsky.social @bruceverchere.bsky.social
& others not on BSky.

Photo shows a picture of a man with text beside him, describing the Geoffrey L Hammond lectureship at BC Children’s Hospital Research Institute

Photo showing 10 plaques that each have a picture and name on them.

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Reposted by Bruce Verchere

Diabetologia @diabetologiajnl.bsky.social · May 8

New study on novel translation factor EIF2A led by Panzhinskiy as a collaboration between @jimjohnsonsci.bsky.social lab, Jan lab & @bruceverchere.bsky.social lab UBC Life Sciences Institute. Thanks Breakthrough T1D Canada for funding this project #DiabetesResearch link.springer.com/article/10.1...

Eukaryotic translation initiation factor 2A protects pancreatic beta cells during endoplasmic reticulum stress while rescuing global translation inhibition - Diabetologia

Aims/hypothesis The endoplasmic reticulum (ER) stress-induced unfolded protein response helps determine beta cell survival rate in diabetes. The alternative eukaryotic translation initiation factor 2A...

link.springer.com

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Bruce Verchere @bruceverchere.bsky.social · Apr 20

and can play anywhere!

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Reposted by Bruce Verchere

Kayla King, Ph.D. @kayla-king.bsky.social · Mar 31

Come join us at beautiful UBC! The King Lab is recruiting a Post-doc Fellow to develop mathematical theory on infectious disease evolution and emergence, together with Ben Ashby (SFU) #zoonoses #biodiversity www.zoology.ubc.ca/kinglab/join...

Join Us! | King Lab

Are you interested in joining the King Lab? More information here!

www.zoology.ubc.ca

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Bruce Verchere @bruceverchere.bsky.social · Mar 20

Always enjoy this discussion of islet biology and other things like reproducibility in science with @danieljdrucker.bsky.social and fantastic @cirtn.bsky.social grad students from across Canada each year!

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Bruce Verchere @bruceverchere.bsky.social · Mar 20

Thanks for hosting us!
Such great diabetes and nutrition research, wonderful people, lovely location, outstanding trainee presentations, and fun social events!

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Reposted by Bruce Verchere

Francis Lynn 🇨🇦 @nictitate.bsky.social · Mar 10

We're looking for postdoctoral scholars to join our team in Vancouver 🇨🇦. We work on cell-based approaches aimed at curing type 1 diabetes. Bring your own ideas for projects or work on one that's already funded! More details here: www.nature.com/naturecareer...

Postdoctoral Research Fellow - Vancouver, British Columbia (CA) job with University of British Columbia Department of Surgery | 12837375

The successful candidate will work on a project developing cell-based therapies for those living with type 1 diabetes (T1D).

www.nature.com

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Bruce Verchere @bruceverchere.bsky.social · Feb 21

Mr Milchick is reviewer 3 though.

Bruce Verchere @bruceverchere.bsky.social · Feb 12

Kicking off the ~15th annual A-BC Islet Workshop at beautiful Silver Star resort in BC. Great islet talks from trainees and keynotes @linnemannlab.bsky.social and @soleimanpourlab.bsky.social
@ubcdiabetes.bsky.social

Outside picture in the snow of ~75 attendees at the A-BC Islet Workshop in Silver Star.

Beautiful sunrise at about 7:30 AM over the Monashee(?) Mountains to the east of Silver Star.

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Bruce Verchere @bruceverchere.bsky.social · Feb 10

Fantastic opportunity for fellowship in an excellent T1D research training environment working in regenerative medicine and stem cells in the Breakthrough T1D Centre of Excellence at UBC. If you missed the NOI deadline, no worries, you can still apply! Reach out if you have any questions.

Stem Cell Network @stemcellnetwork.ca · Feb 10

Are you applying for the J. Andrew McKee Fellowship in Type 1 Diabetes? 
 
Supported by SCN and Breakthrough T1D (formerly JDRF), this is your chance to join UBC’s Breakthrough T1D Centre of Excellence.

Submit your application by February 27, 2025. ➡️ stemcellnetwork.ca/training/exc...

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Reposted by Bruce Verchere

Mark Cuban @mcuban.bsky.social · Feb 9

This is the most relevant article to NIH and research cuts I’ve seen.

Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !”

globalnews.ca/news/9793403...

How a Canadian scientist and a venomous lizard helped pave the way for Ozempic - National | Globalnews.ca

In 1984, Dr. Daniel Drucker, an endocrinologist from the University of Toronto, discovered a hormone that helped pave the way for popular diabetes drugs such as Ozempic.

globalnews.ca

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Francis Lynn 🇨🇦 @nictitate.bsky.social · Jan 22

We have room and $ for postdoctoral fellows to join our team in beautiful Vancouver 🇨🇦. Get in touch if interested.

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Bruce Verchere @bruceverchere.bsky.social · Dec 13

Well done Scott and team and Pat! Looks like a very nice prep!

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Jim Johnson 🇨🇦 @jimjohnsonsci.bsky.social · Dec 4

ubc.wd10.myworkdayjobs.com/en-US/ubcfac...

We are looking for an imaging master to run a very cool shared microscope - Raman label-free, 2-photon, FLIM, high-res, fast capture, thick live tissue, organoids, high-content screening. We are a dynamic and supportive and fun environment.

Research Associate

Academic Job Category Faculty Non Bargaining Job Title Research Associate Department Johnson Laboratory | Department of Cellular and Physiological Sciences | Faculty of Medicine (James Johnson) Postin...

ubc.wd10.myworkdayjobs.com

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Bruce Verchere @bruceverchere.bsky.social · Dec 3

Looking forward to the shipment, thanks for the support!

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Reposted by Bruce Verchere

Xin Tang @xintang.bsky.social · Nov 28

🚀 Excited to announce that our Lab @UBC is recruiting!
🌟 We're looking for passionate intern, graduate, and postdoc with strong coding/ML backgrounds to join us in advancing AI for single-cell biology & brain-computer interfaces.
🏔️ Vancouver awaits!
👉 tanglab.msl.ubc.ca
📧 [email protected]

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Heiko Lickert @heikolickert.bsky.social · Nov 25

Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”.
doi.org/10.1038/s422...
A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social

Inceptor binds to and directs insulin towards lysosomal degradation in β cells - Nature Metabolism

The insulin inhibitory receptor (inceptor) is found to bind to insulin and to regulate insulin stores by directing proinsulin and insulin towards lysosomal degradation.

doi.org

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Francis Lynn 🇨🇦 @nictitate.bsky.social · Nov 20

Great to have this paper out in diabetesjournals.org/diabetes! Appreciate the feedback from reviewers and funding from BreakthroughT1D that made this work possible. pubmed.ncbi.nlm.nih.gov/39561351/

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Esther Verheyen 🇨🇦 @estherverheyen.bsky.social · Nov 22

And in an effort to build community (after I saw the Swiss starter pack! ) - here's one for scientists in Canada! Let me know who I missed.
go.bsky.app/4owyF32

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Bruce Verchere @bruceverchere.bsky.social · Nov 19

@nictitate.bsky.social deservedly recognized for his outstanding mentorship at the 3rd Canadian Islet Research Training Network meeting in Halifax

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Bruce Verchere @bruceverchere.bsky.social · Nov 19

@bruinjenny1.bsky.social kicking off the 3rd annual Canadian Islet Research Training Network (CIRTN) meeting in Halifax by thanking sponsors, including our BC Diabetes Research Network and Canucks for Kids Fund Childhood Diabetes Labs at BC Children's Hospital! Two days of trainee led islet biology!

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