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cancerconnector.bsky.social
@cancerconnector.bsky.social
60 followers 21 following 7 posts
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Reposted
wvschaik.bsky.social
Not this again

'however, standard culture methods did not yield readily cultivable microbiota.'
natureportfolio.nature.com Nature Portfolio @natureportfolio.nature.com · 5d
The findings of a study in Nature Medicine introduce microbial elements as a component of the brain tumor microenvironment and lay the foundation for future mechanistic and translational studies. go.nature.com/44bO314 #medsky #microbiome 🧪
This is figure 6, which shows intratumoral bacterial 16S signal correlates with the oral and gut microbiota of patients with brain tumor.
November 22, 2025 at 8:14 AM
Reposted
harmitmalik.bsky.social
Sharing this important article... for no reason whatsoever.

"We must also continue to deepen and refine our understanding of fundamental biological processes because these details frequently hold the keys to major advances in applied research."

elifesciences.org/articles/102...
November 23, 2025 at 12:21 AM
Reposted
cbo.bsky.social
✅ Addresses important fundamental questions
✅ Uses insanely creative methods
✅ Gives us a truly new picture of how a tricky phenomenon works

Outstanding.
baym.lol Michael Baym @baym.lol · 6d
Hot off the press! Our latest paper led by @fernpizza.bsky.social, understanding how plasmids evolve inside cells. These small, self-replicating DNA circles live inside bacteria and carry antibiotic resistance genes, but also compete with one another to replicate. 1/
www.science.org/doi/10.1126/...
Intracellular competition shapes plasmid population dynamics
From populations of multicellular organisms to selfish genetic elements, conflicts between levels of biological organization are central to evolution. Plasmids are extrachromosomal, self-replicating g...
www.science.org
November 21, 2025 at 11:56 AM
Reposted
scarpino.bsky.social
🔥🔥🔥
netsciconf.bsky.social NetSci 2026 @netsciconf.bsky.social · 6d
𝗗𝘂𝗻𝗰𝗮𝗻 𝗪𝗮𝘁𝘁𝘀 & 𝗦𝘁𝗲𝘃𝗲𝗻 𝗦𝘁𝗿𝗼𝗴𝗮𝘁𝘇 will give their first-ever 𝗷𝗼𝗶𝗻𝘁 𝗸𝗲𝘆𝗻𝗼𝘁𝗲 at NetSci 2026! Their groundbreaking work has shaped how we understand networks, & this session will be a highlight of NetSci’s 20th anniversary.
Call for abstracts: tinyurl.com/3tbj2v83
Call for satellites: tinyurl.com/42sru6kz
November 21, 2025 at 11:52 AM
Reposted
science.org
Have wild wolves learned to use tools?

Learn more: https://scim.ag/4a1MXZv
November 21, 2025 at 2:30 PM
Reposted
carlzimmer.com
"At this time, I suggest the general public avoid the CDC website." --epidemiologist @kkjetelina.bsky.social open.substack.com/pub/yourloca...
One of CDC’s final blows. And what it means for you.
Where to find trusted health information now?
open.substack.com
November 21, 2025 at 3:23 PM
Reposted
science.org
"In the end, I have come to realize that being authentic at work is not a weakness, but rather a strength." #ScienceWorkingLife https://scim.ag/49B7hRv
An illustration of a woman wearing an axolotl costume in front of an audience, with text: Embracing my silly side makes me a better scientist. I wish I’d done it sooner
November 21, 2025 at 8:59 PM
Reposted
baym.lol
Hot off the press! Our latest paper led by @fernpizza.bsky.social, understanding how plasmids evolve inside cells. These small, self-replicating DNA circles live inside bacteria and carry antibiotic resistance genes, but also compete with one another to replicate. 1/
www.science.org/doi/10.1126/...
Intracellular competition shapes plasmid population dynamics
From populations of multicellular organisms to selfish genetic elements, conflicts between levels of biological organization are central to evolution. Plasmids are extrachromosomal, self-replicating g...
www.science.org
November 20, 2025 at 9:42 PM
cancerconnector.bsky.social
Started a Wikipedia page for fitness seascapes! Please consider adding to it and sharing its existence, it’s just a start!

en.wikipedia.org/wiki/Fitness...

@cbo.bsky.social @carlzimmer.com
@sandyanderson.bsky.social @cancerevo.org @mathonco.bsky.social @arvidagren.bsky.social
Fitness seascape - Wikipedia
en.wikipedia.org
November 20, 2025 at 9:57 PM
Reposted
cbo.bsky.social
"What James Watson got wrong about DNA"

By the great Sohini Ramachandran (@sramach.bsky.social) and your boy for The Boston Globe (@bostonglobe.com).

www.bostonglobe.com/2025/11/14/o...
What James Watson got wrong about DNA - The Boston Globe
The science he helped pioneer consistently undermines his view that genes determine everything about us.
www.bostonglobe.com
November 14, 2025 at 4:50 PM
Reposted
biorxiv-medrxiv.bsky.social
Jacob Scott, a founding bioRxiv and medRxiv Affiliate with 73 preprints posted, loves the community of open science advocates around the preprint servers. Thanks to Affiliates like him, preprints are posted ~48 hours after submission.
#bioRxiv #openRxiv #OpenScience #preprints #CommunityVoices
bioRxiv Community Voices graphic featuring Jacob Scott, from Case Western Reserve University (USA). The post has a headshot of Jacob and the quote "Scientific advances are too important to hide behind paywalls." The footer says "bioRxiv and medRxiv are preprint servers of openRxiv."
November 13, 2025 at 6:00 PM
Reposted
jci.org
Personalized treatment in HPV+ oropharynx cancer using genomic adjusted radiation dose

@cancerconnector.bsky.social & team analyze gene expression profiles in patients with HPV+ OSCC & provide a model that outperforms standard measures for predicting OS:
www.jci.org/articles/vie...
October 9, 2025 at 1:05 PM
Reposted
the-asci.org
Personalized treatment in HPV+ oropharynx cancer using genomic adjusted radiation dose

ASCI member @cancerconnector.bsky.social & team analyze gene expression profiles in patients with HPV+ OSCC & provide a model that outperforms standard measures for predicting OS: www.jci.org/articles/vie...
October 9, 2025 at 4:07 PM
cancerconnector.bsky.social
🚨 New in @JClinInvest 🚨
HPV+ oropharynx patients do not all benefit equally from the same radiation dose.
Our study shows that genomics (via GARD) can guide personalized RT de-escalation—safely sparing toxicity without losing cure.
Paper 👉 doi.org/10.1172/JCI194…#ASTRO2525
October 1, 2025 at 12:16 AM
Reposted
kylejcard.bsky.social
It was a pleasure working with this talented, multidisciplinary team: Dena Crozier, Arda Durmaz, Jason Gray, Justin Creary, Amira Stocks, @jeffmaltas.bsky.social, Robert Bonomo, Zachary Burke, and Jacob Scott.

👉 Paper link: www.pnas.org/doi/10.1073/...
5/5
Evolution under vancomycin selection drives divergent collateral sensitivity patterns in Staphylococcus aureus | PNAS
Staphylococcus aureus bacteremia is typically treated empirically with vancomycin, with therapy later tailored based on susceptibility results. How...
www.pnas.org
September 27, 2025 at 5:40 PM
cancerconnector.bsky.social
Looking for a new team member to join us on our journey of discovery.

#mathonco #evolution #antibioticresistance

@cbo.bsky.social @sandyanderson.bsky.social @mathonco.bsky.social @natphys.nature.com @aaas.org
Picture of a team and description of the science we’ve been up to.
September 1, 2025 at 2:42 PM
Reposted
petrovadmitri.bsky.social
So happy and so proud! @alisonfeder.bsky.social keeps hitting it out of the park and so appropriately gathering all the accolades! members.smbe.org/news/Details...
SMBE 2025 Faculty Award Winners
SMBE is delighted to announce our 2025 Faculty Award Winners! Early-Career Excellence Award winner: Alison Feder Alison Feder is an Assistant Professor of Genome Sciences at the University of Washingt...
members.smbe.org
June 25, 2025 at 10:24 PM
Reposted
sandyanderson.bsky.social
Opening 1 of 3 parallel #mathonco sessions this AM is Thomas Yankeelov from @utaustin.bsky.social shows "A practical computational framework for systematically investigating alternative treatment strategies for cancer”. Tom show realworld results from a digital twins driven clinical trial! #SMB2025
July 14, 2025 at 5:17 PM
Reposted
sandyanderson.bsky.social
Next up is former student & friend @stroblmar.bsky.social presenting new work with @cancerconnector.bsky.social on “Bridging the gap: What preclinical experiments can teach us about cancer drug scheduling” #MathOnco #SMB2025
July 14, 2025 at 5:18 PM
Reposted
sandyanderson.bsky.social
Next up is Sara Hamis @uppsalauniversity.bsky.social in a parallel #MathOnco session on "Growth rate-driven modelling elucidates phenotypic adaptation in BRAFV600E-mutant melanoma" #MathOnco #SMB2025
July 14, 2025 at 5:50 PM
Reposted
kenstruck.bsky.social
June 13, 2025 at 10:52 PM
cancerconnector.bsky.social
Of interest to my @bsky.app evol friends @carlzimmer.com @cbo.bsky.social @sandyanderson.bsky.social @cancerevo.org and more I can’t think of bc new platform
June 13, 2025 at 10:59 PM
Reposted
thetnholler.bsky.social
NEWSOM: "It's a vulgar display. It's the kind of thing you see with Kim Jong Un, Putin, dictators that are weak… How weak do you have to be to commandeer the military for your birthday?“
June 13, 2025 at 2:07 AM
cancerconnector.bsky.social
Big shout out to rising M4 and CWRU MSTP student Eshan King - whose paper came out in @aaas.org Science Advances. connecting the fields of PK-PD and evolutionary modeling using fitness seascapes. #mathevo #mathonco

@cbo.bsky.social @sandyanderson.bsky.social

www.science.org/doi/10.1126/...
Fitness seascapes are necessary for realistic modeling of the evolutionary response to drug therapy
Computational and experimental studies of drug resistance evolution give insights into why some bacteria become resistant.
www.science.org
June 13, 2025 at 10:46 PM
Reposted
sandyanderson.bsky.social
Fantastic @theaacr.bsky.social Cancer Evolution Working Group Seminar #AACRCEWG on Evolution-informed Treatment Vulnerabilities from our very own @mathonco.bsky.social Renee Brady & @cancerconnector.bsky.social. Intro from co-chairs Anna Barker & @jeffreytownsend.bsky.social & host Jason Somarelli
May 19, 2025 at 2:38 PM