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Life Science Alliance @lsajournal.org · Aug 25

The Authors have found that overexpression of the centriolar protein SAS-6 causes an increase in cell invasion through the activation of the YAP/TAZ pathway @cengem.bsky.social @tanosbarbara.bsky.social
www.life-science-alliance.org/content/8/10...

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Alessandro Esposito 👨‍🔬🔬🧬👨‍👩‍👧🇪🇺🏳️‍🌈 @aesposito1975.bsky.social · 23d

Happy new academic year for all our students and colleagues at Brunel.

#bruneluniversity #success @cengem.bsky.social

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Life Science Alliance @lsajournal.org · Aug 18

SAS-6 promotes invasion through YAP pathway activation @cengem.bsky.social @tanosbarbara.bsky.social
www.life-science-alliance.org/content/8/10...

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Barbara Tanos @tanosbarbara.bsky.social · Aug 18

Thrilled for the publication of our latest paper on the role of SAS-6 in invasion.
This was a pre-pandemic and post-pandemic effort that would not have been possible without our students and the support of so many colleagues and friends!

@zech-lab.bsky.social @cengem.bsky.social #cilia #centrioles

Life Science Alliance @lsajournal.org · Aug 18

SAS-6 promotes invasion through YAP pathway activation @cengem.bsky.social @tanosbarbara.bsky.social
www.life-science-alliance.org/content/8/10...

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Centre for Genome Engineering and Maintainance @cengem.bsky.social · Jul 3

We now have the audio summary of "#BMP antagonist #CHRDL2 enhances the #cancer #stemcell phenotype and increases #chemotherapy resistance in #colorectal cancer" by Eloise Clarkson and Annabelle Lewis published in Molecular Oncology
open.spotify.com/episode/3vv8...

E03 - CHRDL2 in Colorectal Cancer [New paper from Lewis Lab]

CenGEM | Centre for Genome Engineering and Maintenance · Episode

open.spotify.com

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Centre for Genome Engineering and Maintainance @cengem.bsky.social · Jun 6

Centre for Genome Engineering and Maintenance at Brunel University of London Research Showcase at Senate House.

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Centre for Genome Engineering and Maintainance @cengem.bsky.social · May 13

When the work of centre members has an impact on people. News from Dr Victor Hernandez and Axovia Therapeutics. #gentherapy #cengem

axoviatherapeutics.com/axovia-thera...

Axovia Therapeutics Presents New Preclinical Data for AXV-101 for the Treatment of Blindness Associated with BBS Mutations at ASGCT - Axovia Therapeutics

London, UK – May 13, 2025 – Axovia Therapeutics Ltd., a biotechnology company developing therapies to address the genetic causes of blindness and obesity, announced the presentation of new preclinical...

axoviatherapeutics.com

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Alessandro Esposito 👨‍🔬🔬🧬👨‍👩‍👧🇪🇺🏳️‍🌈 @aesposito1975.bsky.social · May 1

#Microscopills Episode 1. A brief refresher about what #FRET is and FRET #microscopy can do. A primer in a conversational podcast format.

open.spotify.com/episode/4JoK...

Microscopills E01 - A FRET primer: the basics

Quantitative Biology: Papers and Perspectives · Episode

open.spotify.com

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Alessandro Esposito 👨‍🔬🔬🧬👨‍👩‍👧🇪🇺🏳️‍🌈 @aesposito1975.bsky.social · Dec 17

Dear Colleagues,
I want to ask you a favour. As you know, I joined Brunel two years ago and I am committed to making Biosciences, @cengem.bsky.social and Brunel University of London grow. Bunel is a very special project for me.

Microsoft Forms

bit.ly

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Alessandro Esposito 👨‍🔬🔬🧬👨‍👩‍👧🇪🇺🏳️‍🌈 @aesposito1975.bsky.social · Dec 10

Single nucleic acids probe imaged by #FLIM exemplifies how #fluorescence #lifetimes can reveal physicochemical characteristics of the sample hidden within the mere brightness of the sample. Shared just for fun :) red: high lifetime; blue: low lifetime. Probe: to be announced ;) #livecellimaging

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Barbara Tanos @tanosbarbara.bsky.social · Dec 4

Very humbled and honored to share my story. Thank you @jcellsci.bsky.social and Sara Morais da Silva for the interview!

journals.biologists.com/jcs/article/...

@cengem.bsky.social

Cell scientist to watch – Barbara Tanos

ABSTRACT. Barbara Tanos is a Senior Lecturer in Biomedical Sciences in the Department of Life Sciences at Brunel University London (UK). Barbara received her undergraduate degree from the University o...

journals.biologists.com

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Centre for Genome Engineering and Maintainance @cengem.bsky.social · Dec 4

[new review] Zhang Lab. Recent advances and applications of artificial intelligence in 3D bioprinting. Biophys Rev (Melville)
http://dlvr.it/TGbPnR

Recent advances and applications of artificial intelligence in 3D bioprinting

3D bioprinting techniques enable the precise deposition of living cells, biomaterials, and biomolecules, emerging as a promising approach for engineering functi

dlvr.it

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Centre for Genome Engineering and Maintainance @cengem.bsky.social · Dec 3

[New paper] Roberts Lab. 5-aza-2'-deoxycytidine induces #telomere dysfunction in #breast #cancer cells. Biomed Pharmacother.
http://dlvr.it/TGZ4HL

Redirecting

dlvr.it

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Centre for Genome Engineering and Maintainance @cengem.bsky.social · Dec 2

[New review] Tosi Lab. The role of #diet in #cancer: the potential of shaping public #policy and #clinical outcomes in the UK. Genes Nutr
http://dlvr.it/TGWz87

The role of diet in cancer: the potential of shaping public policy and clinical outcomes in the UK - Genes & Nutrition

dlvr.it

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eLife @elife.bsky.social · Nov 30

Scientists have developed an automated tool to study cell growth and division, including hard-to-study, free-floating blood cancer cells.

Cell cycle tracker

Scientists have developed an automated tool to study cell growth and division, including hard-to-study, free-floating blood cancer cells.

buff.ly

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David Gaboriau @dgaboriau.bsky.social · Dec 1

Useful orders of magnitude

Nikolai Slavov @slavov-n.bsky.social · Dec 1

Timescales in Cell Biology

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Centre for Genome Engineering and Maintainance @cengem.bsky.social · Nov 29

[new paper ] Rudolph Lab. Repurposing Proximity-Dependent Protein Labeling (#BioID2) for Protein Interaction Mapping in E. coli. Methods Mol Biol
http://dlvr.it/TGTj3D

Repurposing Proximity-Dependent Protein Labeling (BioID2) for Protein Interaction Mapping in E. coli

Methods that identify protein-protein interactions are essential for understanding molecular mechanisms controlling biological systems. Proximity-dependent labeling has proven to be a valuable method for revealing protein-protein interaction networks in living cells....

dlvr.it

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Centre for Genome Engineering and Maintainance @cengem.bsky.social · Nov 28

[new review] Karteris Lab. The "Road" to Malignant Transformation from #Endometriosis to Endometriosis-Associated #Ovarian #Cancers (EAOCs): An #mTOR-Centred Review. Cancers (Basel)
http://dlvr.it/TGSRX0

The “Road” to Malignant Transformation from Endometriosis to Endometriosis-Associated Ovarian Cancers (EAOCs): An mTOR-Centred Review

dlvr.it

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Centre for Genome Engineering and Maintainance @cengem.bsky.social · Nov 28

[new paper] Drenos Lab. No Evidence That Vitamin D Levels or Deficiency Are Associated with the Risk of Open-Angle #Glaucoma in Individuals of European Ancestry: A Mendelian Randomisation Analysis. Genes
http://dlvr.it/TGSQdz

No Evidence That Vitamin D Levels or Deficiency Are Associated with the Risk of Open-Angle Glaucoma in Individuals of European Ancestry: A Mendelian Randomisation Analysis

dlvr.it

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Centre for Genome Engineering and Maintainance @cengem.bsky.social · Nov 26

[New #preprint] Sisu Lab. #GENCODE: massively expanding the #lncRNA catalog through capture long-read #RNA sequencing. http://dlvr.it/TGPqVQ

GENCODE: massively expanding the lncRNA catalog through capture long-read RNA sequencing

dlvr.it

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Centre for Genome Engineering and Maintainance @cengem.bsky.social · Nov 25

[new paper] Sisu lab. GENCODE 2025: reference gene annotation for human and mouse
http://dlvr.it/TGNfV3

GENCODE 2025: reference gene annotation for human and mouse

Abstract. GENCODE produces comprehensive reference gene annotation for human and mouse. Entering its twentieth year, the project remains highly active as n

dlvr.it

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Centre for Genome Engineering and Maintainance @cengem.bsky.social · Nov 24

[new review paper] Silva Lab. #Breast #cancer risk and prevention in 2024: An overview from the Breast Cancer UK - Breast Cancer Prevention Conference - Cancer Medicine
http://dlvr.it/TGMWyN

Breast cancer risk and prevention in 2024: An overview from the Breast Cancer UK ‐ Breast Cancer Prevention Conference

Breast Cancer Risk Factors Mechanism and Epidemiology Research. Chemicals such as bisphenols, PFOS and aluminium have extensive research into their mechanism of action in cell lines and animal models...

dlvr.it

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bioRxivpreprint @biorxivpreprint.bsky.social · Nov 21

Signaling downstream of tumor-stroma interaction regulates mucinous colorectal adenocarcinoma apicobasal polarity https://www.biorxiv.org/content/10.1101/2024.11.20.624298v1

Mucinous colorectal carcinoma (MUC CRC) dissemination into the tumor stroma and metastasis to multip

www.biorxiv.org

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Ronan McCarthy @ronanmccarthy.bsky.social · Nov 21

Very excited to be co-chairing the British Society of Antimicrobial Chemotheraphy Antibiotic Resistance and Mechanisms conference with @friendlymicrobe.bsky.social
Looking forward to 2 days of great talks and networking
@kateduncan.bsky.social
@craigmaclean.bsky.social
@catrinm.bsky.social

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bioRxivpreprint @biorxivpreprint.bsky.social · Nov 22

Transient histone deacetylase inhibition induces cellular memory of gene expression and three-dimensional genome folding https://www.biorxiv.org/content/10.1101/2024.11.21.624660v1

Epigenetic memory enables the stable propagation of gene expression patterns in response to transien

www.biorxiv.org

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