Chloé de Canson
@chloedecanson.bsky.social
Formerly assistant professor of philosophy • now bedbound with severe myalgic encephalomyelitis (Long COVID) • philosophy of science, social & formal epistemology • 🇵🇸
Reposted by Chloé de Canson
Great comment from @jefflubellc19.bsky.social in @annfammed.bsky.social.
He argues for the value of patient and caregiver observations and hypotheses, saying journals should publish more case studies and hypothesis papers from those groups.
Feat. @patientled.bsky.social!
#MedSky #MECFS #hEDS
He argues for the value of patient and caregiver observations and hypotheses, saying journals should publish more case studies and hypothesis papers from those groups.
Feat. @patientled.bsky.social!
#MedSky #MECFS #hEDS
To Ground Research in the Lived Experience of Patients and Caregivers, Give Us a Voice!
My daughter has been diagnosed with a range of chronic conditions, including Hyper-mobile Ehlers-Danlos Syndrome and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). I have approached my r...
www.annfammed.org
November 25, 2025 at 7:57 PM
Great comment from @jefflubellc19.bsky.social in @annfammed.bsky.social.
He argues for the value of patient and caregiver observations and hypotheses, saying journals should publish more case studies and hypothesis papers from those groups.
Feat. @patientled.bsky.social!
#MedSky #MECFS #hEDS
He argues for the value of patient and caregiver observations and hypotheses, saying journals should publish more case studies and hypothesis papers from those groups.
Feat. @patientled.bsky.social!
#MedSky #MECFS #hEDS
Reposted by Chloé de Canson
My Element on science denial is free to download until December 1st! Get it for free while you can!
doi.org/10.1017/9781...
doi.org/10.1017/9781...
Science Denial
Cambridge Core - Philosophy: General Interest - Science Denial
doi.org
November 17, 2025 at 2:09 PM
My Element on science denial is free to download until December 1st! Get it for free while you can!
doi.org/10.1017/9781...
doi.org/10.1017/9781...
This trial enrolled this many participants this quickly because it’s designed to meet the needs of people with Long COVID, and it’s this well designed because it was designed by the amazing @julialmv.bsky.social who lives with Long COVID herself
Patient participation in research is essential
Patient participation in research is essential
500 enrollees in *less than two weeks*! So many clinical trials would take months, or even years, to enroll this number of people.
This is what happens when you plan a trial that meets participants where they are, is not overly onerous, and tests something people think is worth trying.
This is what happens when you plan a trial that meets participants where they are, is not overly onerous, and tests something people think is worth trying.
Our randomized, placebo-controlled trial of tirzepatide (Zepbound) for #LongCovid has already enrolled 500 participants of 1000 planned in less than 2 weeks!
longcovid.scripps.edu/locitt-t/
longcovid.scripps.edu/locitt-t/
November 17, 2025 at 8:34 PM
This trial enrolled this many participants this quickly because it’s designed to meet the needs of people with Long COVID, and it’s this well designed because it was designed by the amazing @julialmv.bsky.social who lives with Long COVID herself
Patient participation in research is essential
Patient participation in research is essential
Reposted by Chloé de Canson
LoCITT-T trial was covered by Wired today:
www.wired.com/story/weight...
My comments include:
"For the long Covid population...if you’re requiring people to come into a clinic, you’re systematically excluding the most severely affected folks who are housebound or bedbound."
www.wired.com/story/weight...
My comments include:
"For the long Covid population...if you’re requiring people to come into a clinic, you’re systematically excluding the most severely affected folks who are housebound or bedbound."
Weight-Loss Drug Zepbound Is Being Tested as a Treatment for Long Covid
GLP-1s are being studied for a wide range of conditions. Now, scientists will test whether their anti-inflammatory properties can help alleviate symptoms of long Covid.
www.wired.com
November 14, 2025 at 6:23 PM
LoCITT-T trial was covered by Wired today:
www.wired.com/story/weight...
My comments include:
"For the long Covid population...if you’re requiring people to come into a clinic, you’re systematically excluding the most severely affected folks who are housebound or bedbound."
www.wired.com/story/weight...
My comments include:
"For the long Covid population...if you’re requiring people to come into a clinic, you’re systematically excluding the most severely affected folks who are housebound or bedbound."
Reposted by Chloé de Canson
On this day thirty-two years ago. The Harlow Star, England. 11th November 1993. #mecfs #cfsme #myalgicencephalomyelitis #myalgice
November 11, 2025 at 6:49 AM
On this day thirty-two years ago. The Harlow Star, England. 11th November 1993. #mecfs #cfsme #myalgicencephalomyelitis #myalgice
Reposted by Chloé de Canson
New Comment
Negative results in long COVID clinical trials: choosing outcome measures for a heterogeneous disease
www.thelancet.com/journals/lan...
Negative results in long COVID clinical trials: choosing outcome measures for a heterogeneous disease
www.thelancet.com/journals/lan...
Negative results in long COVID clinical trials: choosing outcome measures for a heterogeneous disease
Long COVID is an umbrella term for the heterogeneous long-term consequences of SARS-CoV-2
infection. It encompasses a wide spectrum of phenotypes (sometimes overlapping), and
its underlying mechanisms...
www.thelancet.com
November 9, 2025 at 7:52 PM
New Comment
Negative results in long COVID clinical trials: choosing outcome measures for a heterogeneous disease
www.thelancet.com/journals/lan...
Negative results in long COVID clinical trials: choosing outcome measures for a heterogeneous disease
www.thelancet.com/journals/lan...
Many Long COVID trials have reported negative results in 2024 and 2025. In our Comment for @thelancetinfdis.bsky.social we argue that inadequate outcome measures might have played a role. (1/12)
November 8, 2025 at 12:08 AM
Many Long COVID trials have reported negative results in 2024 and 2025. In our Comment for @thelancetinfdis.bsky.social we argue that inadequate outcome measures might have played a role. (1/12)
Reposted by Chloé de Canson
1/ I'm excited to share that Franz Knappik’s and my Cambridge Element on Hegel and Colonialism is finally out – open access below! We trace how Hegel defends European colonial rule, including transatlantic slavery, and how that defence runs through his entire philosophical system.
Thread below ⬇️
Thread below ⬇️
Hegel and Colonialism
Cambridge Core - Classical Philosophy - Hegel and Colonialism
www.cambridge.org
October 8, 2025 at 12:44 PM
1/ I'm excited to share that Franz Knappik’s and my Cambridge Element on Hegel and Colonialism is finally out – open access below! We trace how Hegel defends European colonial rule, including transatlantic slavery, and how that defence runs through his entire philosophical system.
Thread below ⬇️
Thread below ⬇️
Peirce’s not-at-all dramatic take on subjective interpretations of probability
September 20, 2025 at 5:15 PM
Peirce’s not-at-all dramatic take on subjective interpretations of probability
Reposted by Chloé de Canson
In the second half of the twentieth century, Bayesians began to hold that they had a solution to the problem of induction. What is this solution exactly, what does it tell us about the problem of induction, and does the solution work? You can find out in my new paper!
philpapers.org/rec/CANBAT-3
philpapers.org/rec/CANBAT-3
Chloé de Canson, Bayesianism and the Inferential Solution to Hume’s Problem - PhilPapers
I examine Howson’s alluring suggestion that Bayesianism, by supplying a logic of inductive inference—conditionalisation—solves the problem of induction. I draw on his historical heritage, especially H...
philpapers.org
September 17, 2025 at 4:47 PM
In the second half of the twentieth century, Bayesians began to hold that they had a solution to the problem of induction. What is this solution exactly, what does it tell us about the problem of induction, and does the solution work? You can find out in my new paper!
philpapers.org/rec/CANBAT-3
philpapers.org/rec/CANBAT-3
In the second half of the twentieth century, Bayesians began to hold that they had a solution to the problem of induction. What is this solution exactly, what does it tell us about the problem of induction, and does the solution work? You can find out in my new paper!
philpapers.org/rec/CANBAT-3
philpapers.org/rec/CANBAT-3
Chloé de Canson, Bayesianism and the Inferential Solution to Hume’s Problem - PhilPapers
I examine Howson’s alluring suggestion that Bayesianism, by supplying a logic of inductive inference—conditionalisation—solves the problem of induction. I draw on his historical heritage, especially H...
philpapers.org
September 17, 2025 at 4:47 PM
In the second half of the twentieth century, Bayesians began to hold that they had a solution to the problem of induction. What is this solution exactly, what does it tell us about the problem of induction, and does the solution work? You can find out in my new paper!
philpapers.org/rec/CANBAT-3
philpapers.org/rec/CANBAT-3
Reposted by Chloé de Canson
I’d be grateful if more were written on RFK’s AIDS denialism—important context IMO when we hear him say things like, Long Covid docs are being ignored like docs were ignored in the AIDS crisis. I think he’s dog-whistling alternative therapies that posited lifestyle and not HIV caused AIDS.
"Senator Todd Young (R-IN) Questions Sec. Kennedy on Long COVID, September 4, 2025"
H/T @yogafogie.bsky.social
www.youtube.com/watch?v=t8pb...
H/T @yogafogie.bsky.social
www.youtube.com/watch?v=t8pb...
Senator Young Questions Sec. Kennedy on Long COVID, September 4, 2025
YouTube video by Michael Sieverts
www.youtube.com
September 5, 2025 at 2:13 PM
I’d be grateful if more were written on RFK’s AIDS denialism—important context IMO when we hear him say things like, Long Covid docs are being ignored like docs were ignored in the AIDS crisis. I think he’s dog-whistling alternative therapies that posited lifestyle and not HIV caused AIDS.
Reposted by Chloé de Canson
In a @bmj.com survey of 183 patient/public #PeerReviewers assaying their experience, perspectives on payment (£50 or an online #BMJ journal subscription) (69% response rate), 84% reported a good/very good experience, 48% might be more likely to review @emmajdoble.bsky.social @amyprice.bsky.social
September 4, 2025 at 9:45 PM
In a @bmj.com survey of 183 patient/public #PeerReviewers assaying their experience, perspectives on payment (£50 or an online #BMJ journal subscription) (69% response rate), 84% reported a good/very good experience, 48% might be more likely to review @emmajdoble.bsky.social @amyprice.bsky.social
Reposted by Chloé de Canson
Hot off the press: Michael Kremer’s and my resurrection of Margaret Macdonald.
August 26, 2025 at 5:56 PM
Hot off the press: Michael Kremer’s and my resurrection of Margaret Macdonald.
Really recommend this paper on the production of ignorance (agnotology) in medicine!
Forthcoming in SHPS 'A pink lie in French medicine' where I tell you the story of Spasfon/phloroglucinol - a pink shiny pill created in France in the 1960s - and one of the most prescribed pharmaceutical drugs in France, especially to women philpapers.org/rec/FERAPL-3
Juliette Ferry-Danini, A pink lie in French medicine - PhilPapers
This paper sets to explain how one of the most prescribed and sold pharmaceutical drugs in France – Spasfon (phloroglucinol), introduced on the French market in the 1960s, became and remained so succe...
philpapers.org
August 21, 2025 at 3:26 PM
Really recommend this paper on the production of ignorance (agnotology) in medicine!
Reposted by Chloé de Canson
Powerful closing remarks from PLRC co-founder @ahandvanish.bsky.social at the Keystone Symposia on #LongCovid last week, reflecting on the state of research and the journey of the patient community:
"In our immediate presence, time slows, while the world beyond speeds up, and moves without us”
"In our immediate presence, time slows, while the world beyond speeds up, and moves without us”
August 19, 2025 at 6:20 PM
Powerful closing remarks from PLRC co-founder @ahandvanish.bsky.social at the Keystone Symposia on #LongCovid last week, reflecting on the state of research and the journey of the patient community:
"In our immediate presence, time slows, while the world beyond speeds up, and moves without us”
"In our immediate presence, time slows, while the world beyond speeds up, and moves without us”
Reposted by Chloé de Canson
This is why pwME get so upset when newcomers to the field don’t engage existing experts. We have lost so, so much time, and critical information, to people who refuse to build on existing knowledge.
They’ve literally been reinventing the wheel for no reason
August 17, 2025 at 7:44 PM
This is why pwME get so upset when newcomers to the field don’t engage existing experts. We have lost so, so much time, and critical information, to people who refuse to build on existing knowledge.
Reposted by Chloé de Canson
Indeed. And further..
EVERYTHING👏DIAMOND👏OPEN👏ACCESS👏OR👏JUST👏FIND👏THE👏PREPRINTS/PIRATE👏IT👏
EVERYTHING👏DIAMOND👏OPEN👏ACCESS👏OR👏JUST👏FIND👏THE👏PREPRINTS/PIRATE👏IT👏
Every now again it’s useful to repeat advice about accessing papers that are behind a paywall that excludes you. Email the author. My estimate is that 90% of academics are so thrilled that a living, breathing, possibly even reading, person shows interest that they will swiftly send you a copy.
May 3, 2025 at 10:39 PM
Indeed. And further..
EVERYTHING👏DIAMOND👏OPEN👏ACCESS👏OR👏JUST👏FIND👏THE👏PREPRINTS/PIRATE👏IT👏
EVERYTHING👏DIAMOND👏OPEN👏ACCESS👏OR👏JUST👏FIND👏THE👏PREPRINTS/PIRATE👏IT👏
Reposted by Chloé de Canson
Just reupping this paper in which Chloé lays out systematically the reasons enlisting lived experience reviewers can help reduce errors that scientists without that experience are prone to.
Why? No reason 🙃
Why? No reason 🙃
My paper is forthcoming in Philosophy of Science!
Drawing on the examples of HIV/AIDS and IACCs (incl. Long COVID), I argue that lay interference with the conduct of science can improve the accuracy of scientific outputs and propel science forward. Some main points ⬇️
philarchive.org/rec/CANTEG
Drawing on the examples of HIV/AIDS and IACCs (incl. Long COVID), I argue that lay interference with the conduct of science can improve the accuracy of scientific outputs and propel science forward. Some main points ⬇️
philarchive.org/rec/CANTEG
Chloé de Canson, The Epistemic Grounds for Lay Interference in the Conduct of Science - PhilArchive
I present a heretofore untheorised form of lay science, called extitutional science, whereby lay scientists, by virtue of their collective experience, are able to detect errors committed by institutio...
philarchive.org
August 16, 2025 at 6:13 PM
Just reupping this paper in which Chloé lays out systematically the reasons enlisting lived experience reviewers can help reduce errors that scientists without that experience are prone to.
Why? No reason 🙃
Why? No reason 🙃
Reposted by Chloé de Canson
“DecodeME shows the incredible level of support that the ME/CFS patient community can give to research that involves them on a deep and meaningful level. Without the community, we could not have achieved all that we have.” Andy Devereux-Cooke (PPI Member and Co-Investigator)
August 15, 2025 at 8:45 AM
“DecodeME shows the incredible level of support that the ME/CFS patient community can give to research that involves them on a deep and meaningful level. Without the community, we could not have achieved all that we have.” Andy Devereux-Cooke (PPI Member and Co-Investigator)
My paper has been assigned to an issue at Mind! I argue that the algebra of propositions on which an agent’s credences are defined cannot be relativised to their “awareness context”, but they can be relativised to what the agent considers possible
academic.oup.com/mind/article...
academic.oup.com/mind/article...
On Algebra Relativisation
Abstract. Katie Steele and H. Orri Stefánsson argue that, to reflect an agent’s limited awareness, the algebra of propositions on which that agent’s creden
academic.oup.com
August 15, 2025 at 2:16 PM
My paper has been assigned to an issue at Mind! I argue that the algebra of propositions on which an agent’s credences are defined cannot be relativised to their “awareness context”, but they can be relativised to what the agent considers possible
academic.oup.com/mind/article...
academic.oup.com/mind/article...
Reposted by Chloé de Canson
Three prominent clinical trials targeting viral persistence in Long COVID with short treatment courses did not find the drugs helped improve people's health. But this is far from the end of the road for persistence trials.
I unpacked the current state of the field @thesicktimes.org: (1/4)
I unpacked the current state of the field @thesicktimes.org: (1/4)
No “easy home runs”: Early Long COVID trials of Paxlovid and monoclonal antibodies failed, but the treatments still have potential - The Sick Times
While three early clinical trials of these drugs did not find they led to health improvements for participants, further trials are getting more intentional in targeting viral persistence.
thesicktimes.org
August 12, 2025 at 4:43 PM
Three prominent clinical trials targeting viral persistence in Long COVID with short treatment courses did not find the drugs helped improve people's health. But this is far from the end of the road for persistence trials.
I unpacked the current state of the field @thesicktimes.org: (1/4)
I unpacked the current state of the field @thesicktimes.org: (1/4)
My paper is forthcoming in Philosophy of Science!
Drawing on the examples of HIV/AIDS and IACCs (incl. Long COVID), I argue that lay interference with the conduct of science can improve the accuracy of scientific outputs and propel science forward. Some main points ⬇️
philarchive.org/rec/CANTEG
Drawing on the examples of HIV/AIDS and IACCs (incl. Long COVID), I argue that lay interference with the conduct of science can improve the accuracy of scientific outputs and propel science forward. Some main points ⬇️
philarchive.org/rec/CANTEG
Chloé de Canson, The Epistemic Grounds for Lay Interference in the Conduct of Science - PhilArchive
I present a heretofore untheorised form of lay science, called extitutional science, whereby lay scientists, by virtue of their collective experience, are able to detect errors committed by institutio...
philarchive.org
August 12, 2025 at 4:21 PM
My paper is forthcoming in Philosophy of Science!
Drawing on the examples of HIV/AIDS and IACCs (incl. Long COVID), I argue that lay interference with the conduct of science can improve the accuracy of scientific outputs and propel science forward. Some main points ⬇️
philarchive.org/rec/CANTEG
Drawing on the examples of HIV/AIDS and IACCs (incl. Long COVID), I argue that lay interference with the conduct of science can improve the accuracy of scientific outputs and propel science forward. Some main points ⬇️
philarchive.org/rec/CANTEG
Excellent reporting (featuring a quote from me!) on what happened to the hotly anticipated BC007 trial for Long COVID, which reported negative results despite reports of major improvements from some trial participants. Bad study design could have led to a false negative
German start-up Berlin Cures announced it would not conduct additional research after a failed #LongCOVID clinical trial of novel drug BC 007.
In collaboration with @statnews.com, @betsyladyzhets.bsky.social dives deep on what went wrong with the trial and what's next for BC 007. bit.ly/44KAwhT
In collaboration with @statnews.com, @betsyladyzhets.bsky.social dives deep on what went wrong with the trial and what's next for BC 007. bit.ly/44KAwhT
July 22, 2025 at 7:12 PM
Excellent reporting (featuring a quote from me!) on what happened to the hotly anticipated BC007 trial for Long COVID, which reported negative results despite reports of major improvements from some trial participants. Bad study design could have led to a false negative