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Reposted by Chris Sundling

TRAstonDrs @castltrastondrs.bsky.social · 20h

#Medsky🧪 #IDsky #immunosky #virosky #Publichealth Based on a study in @sciimmunology.bsky.social , a #covid booster immunization drives a germinal center mediated broadening of #Bcell responses by recalling existing #memoryBcells

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Reposted by Chris Sundling

Justin J. Taylor, PhD @justintaylorlab.bsky.social · 1d

A few years ago, my lab started a list of papers analyzing antigen-specific #Bcells w/ fluorescent probes via #flowcytometry. We are now releasing this list of 700+ papers as a searchable database on my lab website with a short overview. www.biorxiv.org/content/10.1...

Bubble Chart displaying the different types of antigens targeted by B cells in the papers in the database so far. Antigens are grouped into the the viruses, bacteria, parasites, plants, animals, or other sources they come from. And the bubble sizes are scaled to represent how frequently those antigens have been used

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Chris Sundling @chrissundling.bsky.social · 1d

From the now published pan-disease blood atlas, we used the proteomic data together with clinical and single-cell data to describe immune cross-talk linked with disease severity in malaria @cp-immunity.bsky.social

Check it out!

www.sciencedirect.com/science/arti...

#Immunology #malaria @ki.se

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Chris Sundling @chrissundling.bsky.social · 1d

New study on a human pan-disease proteomic blood atlas out in @science.org! www.science.org/doi/10.1126/.... The resource is available at the human protein atlas website: www.proteinatlas.org/humanproteom...

#immunology #Health #Disease @ki.se @scilifelab.se @peternilsson-kth.bsky.social

A human pan-disease blood atlas of the circulating proteome

The human blood proteome provides a holistic readout of health states through the assessment of thousands of circulating proteins. Here, we present a pan-disease resource to enable the study of divers...

www.science.org

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Reposted by Chris Sundling

Seth Thomas Scanlon @immunoeditor.bsky.social · 1d

To celebrate this year’s #NobelPrize in #Medicine, awarded for the discovery of regulatory #TCells, we have selected 8 papers recently published in #Science #Immunology that highlight recent advances in #Treg biology! The collection will be online until the end of Oct 2025!

bit.ly/SciImm_free

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Myriam Nabhan @myriamnabhan.bsky.social · 1d

yEFIS Career webinars are back! #ImmunoSky #career #science

yEFIS @yefis-immunology.bsky.social · 2d

📣 yEFIS Career Fridays start next week!

Your PhD opens more doors than you think — join our 5-week series and hear from immunology & life science PhDs who built amazing careers outside academia.

✨ Learn what they do, what got them there & ask your questions live!

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Reposted by Chris Sundling

Jonas Schmid @joschmd.bsky.social · 2d

MOG antibody-associated disease (MOGAD) affects the central nervous system, but our new immunophenotyping data show that it also profoundly alters circulating immune cells.
www.science.org/doi/10.1126/...
#Immunology #MOGAD #Autoimmunity #Neurology

Immune signatures link myelin oligodendrocyte glycoprotein antibody–associated disease to other autoantibody-mediated conditions

Single-cell immunoprofiling uncovered systemic immune cell signatures of neurological MOG antibody–associated disease.

www.science.org

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Reposted by Chris Sundling

Dr Emma S Chambers @emmaschambers.bsky.social · 2d

I am so proud to say that our paper is now available at Aging Cell. There is a paucity of data as to how the menopause impacts your immune system, and the aim of this study was to investigate the impact of the menopause on monocyte phenotype and function.
onlinelibrary.wiley.com/doi/10.1111/...

Age‐Associated Inflammatory Monocytes Are Increased in Menopausal Females and Reversed by Hormone Replacement Therapy

Post-menopausal females (> 64 years) have an increase in frequency of inflammatory monocyte populations with defective phagocytosis as compared to pre-menopausal (< 40 years) females. Hormone Replace....

onlinelibrary.wiley.com

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Reposted by Chris Sundling

TRAstonDrs @castltrastondrs.bsky.social · 5d

#Medsky🧪 #publichealth @science.org
Blood, sweat & 🍻 Amongst the study of 465 participants, mosquitoes showed a clear fondness for those who drank beer over those who abstained

www.science.org/content/arti...

Does drinking beer make you more attractive to mosquitoes?

Experiments performed at a large music festival suggest the bloodsuckers are more attracted to hedonistic attendees

www.science.org

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Shabaana Khader @khadershabaana.bsky.social · 6d

Dear #microbiology and #immunology community- I took a break from social media after I deleted my Twitter account, but am back here. Please help me rebuild my community by following me and amplifying this message- I will follow you back. Thank you and I look forward to our many interactions!

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Society for Mucosal Immunology @societymucosalimm.bsky.social · 4d

SMI Member Eduardo Villablanca and colleagues review B cells in inflammatory bowel disease at Immunology Letters:
www.sciencedirect.com/science/arti...

#SMIMemberPaper #MucosalImmunology #Immunology

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International Union of Immunological Societies @iuis-online.bsky.social · 3d

🌍 We’re proud to have hosted him in Vienna, where he shared his now–Nobel-winning insights with the IUIS community.
🎥 Watch Prof. Sakaguchi’s full keynote on #Immunohub: loom.ly/nhUTceE

#GlobalImmunology #ImmunologyWithoutBorders #IUIS2025 #NobelPrize

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Science Magazine @science.org · 4d

A new trivalent vaccine based on chimeric alphaviruses shields mice and macaques from infection and CNS pathology when exposed to aerosolized forms of Venezuelan, Eastern, and Western equine encephalitis viruses.

Read more in #ScienceTranslationalMedicine: https://scim.ag/4gSP2Z3

An inactivated trivalent virion-based vaccine protects against aerosol challenge with encephalitic alphaviruses in mice and macaques

Two doses of an inactivated trivalent vaccine protect mice and macaques against disease caused by encephalitic alphaviruses.

scim.ag

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Reposted by Chris Sundling

Kilian Schober @kischober.bsky.social · 7d

If the immune system is an army...
...
would you rather rely on one “super warrior” — or on a diverse team of fighters, even if none of them is the single strongest?

I’d go with the team.

Why? Check out our new study, just published in Science Immunology: www.science.org/doi/10.1126/...

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Matthias Eberl @eberlmat.bsky.social · 8d

Imagine if British newspapers put only half the energy they spent obsessing over Starmer’s curry in Durham into covering the fact that a former top figure in UKIP, the Brexit Party and Reform UK has just pleaded guilty to eight counts of pro-Russian bribery.

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Marc Veldhoen @marcveld.bsky.social · 8d

Differences between influenza and COVID-19 patients who required hospitalization: A study of the 2024–2025 season

Too small to draw strong conclusions from, but there are some points to consider.

www.sciencedirect.co...
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Differences between influenza and COVID-19 patients who required hospitalization: A study of the 2024–2025 season

During the winter and spring of 2024–2025, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) XEC subvariant became the main cause of the ep…

www.sciencedirect.com

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Alexander Dent @follicular.bsky.social · 8d

Well, this is exciting! An autoimmune mechanism for the horrible disease ALS has been identified, for the first time. #ImmunoSky
🧪
www.nature.com/articles/s41...

Autoimmune response to C9orf72 protein in amyotrophic lateral sclerosis - Nature

An analysis of T cell responses in people with amyotrophic lateral sclerosis shows that the C9orf72 antigen is a key target of autoimmune responses in the disease, and identifies C9orf72 epitopes that are recognized.

www.nature.com

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Reposted by Chris Sundling

Pieta Mattila @mattilalab.bsky.social · 8d

Amazing opportunity to do your immunology postdoc in Turku 🤩 Our lab would be more than happy to host a postdoc interested in a project related to B cells. 🥰 Please apply and share the word! academicpositions.com/ad/universit...

IMMUFELLOW Postdoctoral Researcher Positions (Researcher/Senior Researcher) – Up to 11 Positions: 2 at ÅAU and 9 at UTU - Academic Positions

The Interdisciplinary and Intersectoral Research Fellowship Programme for Future Leaders in Immunology (IMMUFELLOW) is an innovative postdoctoral training in...

academicpositions.com

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Reposted by Chris Sundling

TRAstonDrs @castltrastondrs.bsky.social · 8d

#Medsky🧪 #IDsky #pedsky #Episky Recent studies confirms that #LongCOVIDkid is a serious & persistent condition that can affect children, challenging earlier assumptions that children were largely unaffected.
New studies reveal that reinfection significantly increases a child's risk of developing LC

Long COVID is here to stay—even in children

Post-acute sequelae of SARS-CoV-2 infection (PASC, also known as long COVID) are complex, multisystem, long-lasting complications of SARS-CoV-2 infection that profoundly impact the daily life of those...

www.thelancet.com

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Gabriele Pollara @gpollara.bsky.social · 10d

Host-directed therapies for infectious disease are here & coming!

Simple equation proposed to consider best interventions:
⭐ Microorganism + immune response = clinical presentation/status ⭐

Will require futuristic-sounding real-time diagnostics = exciting!

#IDSky #MedSky #ImmunoSky #TBSky

The Changing Paradigm in Infectious Diseases - Host-Directed Medicine: Implications for the Next Generation of ID Physicians

academic.oup.com

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Johannes Nemeth @johannesnemeth.bsky.social · 10d

We just published results from the BELIEVE trial—a small, investigator-initiated study testing BCG vaccination in people with treated HIV. academic.oup.com/ofid/advance...

Safety of Bacillus Calmette-Guérin vaccination and impact on HIV-1 latent reservoir size in people with treated HIV-1 Infection

AbstractBackground. Bacillus Calmette-Guérin (BCG) vaccination, used against tuberculosis, is recognized for its immunomodulatory properties, a phenomenon

academic.oup.com

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Madhu Pai, MD, PhD @madhupai.bsky.social · 16d

With the amount of rubbish disinformation and quackery these days, we all need tylenol!

Cartoon where a woman watching TV says "there's so much stupidicity in this timeline it's giving me a headache" and the man says "take two tylenol"

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Waggoner Lab @labwaggoner.bsky.social · 16d

Human CD4+ T cells recognize Mycobacterium tuberculosis–infected macrophages amid broader responses @jem.org
rupress.org/jem/article/...

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Waggoner Lab @labwaggoner.bsky.social · 17d

HMGB1 couples LEF1 to regulate B cell immunity @jci-insight.bsky.social
insight.jci.org/articles/vie...

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Journal of Experimental Medicine @jem.org · 17d

William J. Branchett, Anne O’Garra @crick.ac.uk et al. reveal that type I signaling early during M. #tuberculosis infection favors #neutrophil swarming and limits CD4+ T cell–#macrophage interactions in #TB lesions, impeding TB disease control. rupress.org/jem/article/...

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