Cihan Erkut
@cihanerkut.bsky.social
230 followers 310 following 18 posts
Computational Biologist | Integrative Genomics of Rare Cancers | Nanopore Sequencing | Division of Applied Functional Genomics | German Cancer Research Center (DKFZ) | National Center for Tumor Diseases (NCT) Heidelberg
Posts Media Videos Starter Packs
Reposted by Cihan Erkut
mpi-scienceoflight.bsky.social
With deep sadness, we share that Prof. Jochen Guck, Director at the Max Planck Institute for the Science of Light passed away on October 3. His visionary work bridged physics and medicine. We have lost a brilliant scientist and dear friend.

mpl.mpg.de/news/article...
@fau.de

📸 Stephan Spangenberg
Professor Jochen Guck, Director at the Max Planck Institute for the Science of Light (MPL), He headed the division “Cell Physics” at MPL and the Max-Planck-Zentrum für Physik und Medizin (MPZPM).
cihanerkut.bsky.social
It has been an honor for me to have worked in this fantastic project with great scientists and brilliant students for the last few years.
Reposted by Cihan Erkut
cancercoreeurope.bsky.social
📢 Registration now open for HARPOON Conference, Nov 27–28 2025 in Heidelberg! Precision oncology, multi-omics, & translational research.

indico.dkfz.de/event/1230/

@nct-heidelberg.bsky.social @dkfz.bsky.social @vhio.bsky.social @ki.se @crukcamcentre.bsky.social @nkinl.bsky.social @gustaveroussy.fr
cihanerkut.bsky.social
That's cool!!!
posit.co
Posit @posit.co · Aug 13
Announcing Positron's dedicated console for interactive coding!

Run single lines of #RStats or #Python code, switch languages & versions on the fly, and quickly scan outputs.

Learn more about Positron’s dedicated console: positron.posit.co
Reposted by Cihan Erkut
tanentzapflab.bsky.social
The goal of a PhD is not to learn some facts or read a few papers or learn a bunch of techniques. The goal of a PhD is to learn independence, problem solving, how to finish things you start, resilience, & gain the ability to adapt & think creatively. Learning these things is hard.
Reposted by Cihan Erkut
rbreich.bsky.social
Your Prime Day reminder that half of Amazon warehouse workers struggle with food & housing costs.

A third have had to rely on government assistance like SNAP — which is about to get cut.

If Bezos can spend $50M on a wedding, Amazon can afford to treat its workers with dignity.
cihanerkut.bsky.social
After so many inspiring talks and thought-provoking conversations, it's now time to go home. Many thanks to the organizers of #EACR2025 for this extraordinary event. Hope to meet everyone again next year in Budapest.
cihanerkut.bsky.social
If you are at the #EACR2025 today and interested in integrative genomics of rare cancers, feel free to visit me by the poster P-006 in Pavilion 1 during the poster session.
cihanerkut.bsky.social
This was one of the most inspiring talks I've ever heard in my life!

#eacr2025
luisa86ferreira.bsky.social
Jan H. Hoeijmakers shared mindblowing insights on how caloric restriction impact on DNA damage response, cancer, and ageing! Also unexpected effects of carbohydrate and fat vs protein intake. (Less) food for thought —literally!
#EACR2025
Reposted by Cihan Erkut
johannajoyce.bsky.social
Incredible opening keynote by Charlie Swanton - spanning tumour initiation, aging, environmental exposure and much more 👏👏

#EACR2025
@charlesswanton.bsky.social
@crick.ac.uk
@helloeacr.bsky.social
cihanerkut.bsky.social
Sounds very interesting to me 😂
Reposted by Cihan Erkut
etep-isolde.bsky.social
„Kinder, die lernen, ihre eigenen Gefühle zu verstehen, können auch die Gefühle anderer besser wahrnehmen.“
Lisa Feldman Barrett
#blueLZ
Reposted by Cihan Erkut
janelleshane.com
1. LLM-generated code tries to run code from online software packages. Which is normal but
2. The packages don’t exist. Which would normally cause an error but
3. Nefarious people have made malware under the package names that LLMs make up most often. So
4. Now the LLM code points to malware.
daviddlevine.com
LLMs hallucinating nonexistent software packages with plausible names leads to a new malware vulnerability: "slopsquatting."
LLMs can't stop making up software dependencies and sabotaging everything
: Hallucinated package names fuel 'slopsquatting'
www.theregister.com
Reposted by Cihan Erkut
wissenschaftsrat.de
The German Science and Humanities Council and the German Rectors' Conference criticise attacks on academic freedom and declares its solidarity with US institutions and scientists. An attack on science anywhere is an attack on science everywhere. #AcademicFreedom #HandsOff
Reposted by Cihan Erkut
stefanfrohling.bsky.social
Are you interested in groundbreaking research in the field of personalized cancer therapies? If so, please join us at DKFZ for an exciting and inspiring afternoon and hear from key opinion leaders and rising stars about what is on the horizon.
nct-heidelberg.bsky.social
** Meyenburg-Preis an Michel Sadelain **
🏆Verleihung im Rahmen des Cancer Research Award Symposiums der Meyenburg-Stiftung
📅 2. April 2025 am Deutschen Krebsforschungszentrum in Heidelberg

Programm und Anmeldung unter www.nct-heidelberg.de/das-nct/news...

@dkfz.bsky.social
Reposted by Cihan Erkut
nct-heidelberg.bsky.social
** Meyenburg-Preis an Michel Sadelain **
🏆Verleihung im Rahmen des Cancer Research Award Symposiums der Meyenburg-Stiftung
📅 2. April 2025 am Deutschen Krebsforschungszentrum in Heidelberg

Programm und Anmeldung unter www.nct-heidelberg.de/das-nct/news...

@dkfz.bsky.social
Reposted by Cihan Erkut
micamer.bsky.social
We would love feedback on a new NCBI-BLAST service we are launching today: sky-blast.com

Under the hood it's the same BLAST executable and databases provided by NCBI, with a replica of the NIH's interface - providing an alternative to the US gov service that's less congested, faster & more reliable
Reposted by Cihan Erkut
richardsever.bsky.social
Big news: we are setting up a new non-profit organization to run bioRxiv and medRxiv. It's called openRxiv [no it's not a new preprint server; it's dedicated organization to oversee the servers] openrxiv.org 1/n
Homepage - openRxiv
openRxiv is an independent non-profit, the new organizational home for bioRxiv and medRxiv, enabling researchers to instantly share groundbreaking findings with the global scientific community.
openrxiv.org
Reposted by Cihan Erkut
ghga.bsky.social
New release headed by GHGA Member Kübra Narcı! This pipeline is designed to assess and validate the accuracy of variant calling methods in genomic research.
Reposted by Cihan Erkut
wkhuber.bsky.social
Heidelberg 2025-02-15
Reposted by Cihan Erkut
winklerlab.bsky.social
#aufstehenfuerdemokratie

Um 11:55 Uhr versammelte sich eine große Gruppe von Wissenschaftlern & Unterstützern, um ein Statement für faktenbasierte Entscheidungen und Demokratie abzugeben:

Geht wahlen-mit Verstand!

Inspirierende Worte von Prof. E. Winkler und Prof. S. Pfister -
Danke an Alle!
Reposted by Cihan Erkut
nadia-davidson.bsky.social
Our new paper examining how to analyse longread RNA-seq with no reference genome. We compare approaches for assembly and downstream analysis, from transcript accuracy to differential expression. Lead by @alexyfyf.bsky.social. Thnx to all contributors incl. @qgouil.bsky.social for the pea data!
cihanerkut.bsky.social
genetic background, age, sex, nutrition, etc. I strongly advice my colleagues not to use DESeq to analyze patient cohorts. I just wanted to sharey thoughts.
cihanerkut.bsky.social
Additionally, there is the latent variable issue. Tumor samples are rarely 100% pure. Even if there is no contaminating normal tissue, the tumor microenvironment (immune cells, etc.) differ between tumors of the same type. Then, of course, there are so many other factors such as treatment regime,
cihanerkut.bsky.social
There, replicates of the same experiment group can be truly biological replicates, if the experiment is designed properly. For human samples in TCGA cohorts, that's never the case. Ever sample is individual. So DESeq fails to model the dispersion to start with, regardless of sample size.