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Dane Parker

@daneparkerlab.com

400 followers 270 following 35 posts

Laboratory of Dane Parker 🇦🇺 Rutgers NJMS USA. Bacterial pathogenesis, host-pathogen interactions and innate immunity. Staphylococcus aureus. Interferons. Trained immunity. Center for Infection and Immunity. #immunology, #microbiology. www.daneparkerlab.com

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Dane Parker @daneparkerlab.com · Aug 4

Latest from the lab! In @elife.bsky.social we reviewed the current status of trained immunity in the lung!

elifesciences.org/articles/104...

Trained immunity in the lung

Several studies have now demonstrated that trained immunity occurs in the airways to several pathogens and products, while its utility is yet to be determined.

elifesciences.org

Reposted by Dane Parker

Ilyas Alav @ilyasalav.bsky.social · 18d

My nose must be riddled with S. aureus then 🫠

Nature Microbiology @natmicrobiol.nature.com · 18d

#NewResearch

Nasal colonisation by S. aureus is linked with depression in a human cohort and shown in a mouse model to cause decreased serotonin and dopamine in the brain

#MicroSky #Depression

www.nature.com/articles/s41...

Nasal Staphylococcus aureus carriage promotes depressive behaviour in mice via sex hormone degradation - Nature Microbiology

Nasal colonization by Staphylococcus aureus is linked with depression in a human cohort and shown in a mouse model to cause decreased serotonin and dopamine in the brain.

www.nature.com

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Dane Parker @daneparkerlab.com · Aug 6

Latest from the lab!!! We joined Amali Samarasinge and Charles Dela Cruz and a cast of many on a workshop for best practices for models of bacterial pneumonia @atscommunity.bsky.social

www.atsjournals.org/doi/full/10....

Best Practices in the Development and Use of Experimental Models of Bacterial Pneumonia: An Official American Thoracic Society Workshop Report | American Journal of Respiratory Cell and Molecular Biol...

www.atsjournals.org

Dane Parker @daneparkerlab.com · Aug 4

Latest from the lab! In @elife.bsky.social we reviewed the current status of trained immunity in the lung!

elifesciences.org/articles/104...

Trained immunity in the lung

Several studies have now demonstrated that trained immunity occurs in the airways to several pathogens and products, while its utility is yet to be determined.

elifesciences.org

Dane Parker @daneparkerlab.com · Jun 22

Mice are not always reflective of human studies!

Theobald Smith Society @njmicrobe.bsky.social · Jun 22

A Rutgers study shows Acinetobacter baumannii hits men harder than women— longer ICU stays, higher severity, and more co-infections. Surprising contrast to mouse data. Sex matters in infectious disease. go.njmicrobe.org/e5DGRy #Microbiology #InfectiousDisease #Rutgers #SexDifferences #Acinetobacter

Unveiling the Hidden Impact: How Biological Sex Influences Acinetobacter baumannii Pneumonia Outcomes

Acinetobacter baumannii is a formidable adversary in healthcare settings, recognized by the World Health Organization as a critical priority pathogen due to its strong association with multidrug-resis...

go.njmicrobe.org

Reposted by Dane Parker

Frances Yap @ribo1214.bsky.social · Jun 10

1,600 names needed toward the next 12,800 target. Support NIH and research

SBGrid Consortium @sbgrid.bsky.social · Jun 10

Stand up for science and sign your name in support of NIH staff and The Bethesda Declaration: A Call for NIH and HHS Leadership to Deliver on Promises of Academic Freedom and Scientific Excellence.

actionnetwork.org/forms/add-na...

ADD YOUR NAME: Sign the Open Letter in Support of NIH Staff

Join the courageous and committed National Institutes of Health (NIH) public servants by adding your name now.

actionnetwork.org

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Dane Parker @daneparkerlab.com · Jun 3

Virologists!! We are hiring at all levels. Check it out!

jobs.sciencecareers.org/job/672389/v...

VIROLOGY FACULTY RECRUITING AT RUTGERS NEW JERSEY MEDICAL SCHOOL - Newark, NJ job with Rutgers New Jersey Medical School | 672389

The New Center for Virus-Host-Innate Immunity (CVHII) at Rutgers New Jersey Medical School (NJMS), Newark, is seeking to recruit tenure-track faculty.

jobs.sciencecareers.org

Dane Parker @daneparkerlab.com · May 27

Thanks!

Dane Parker @daneparkerlab.com · May 27

Thanks!

Dane Parker @daneparkerlab.com · May 27

Such an honor to receive the Rutgers New Jersey Medical School Faculty Organization Faculty of the Year Award.

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Dane Parker @daneparkerlab.com · May 23

Spiaggia Bianco heaven!

Reposted by Dane Parker

Mucosal Immunology @mucosalimmunol.bsky.social · May 19

An improved humanized mouse model of Staphylococcus aureus infection to study pneumonia from @daneparkerlab.com www.mucosalimmunology.org/article/S193...

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Dane Parker @daneparkerlab.com · May 13

Latest from the lab! We show in @mucosalimmunol.bsky.social
a new humanized mouse model of S. aureus infection using human lung tissue examining the immune and bacterial responses! #OpenAccess
www.mucosalimmunology.org/article/S193...

Improved humanized mouse model of Staphylococcus aureus infection

Staphylococcus aureus is a significant cause of pulmonary infections, but existing mouse models fail to recapitulate human-specific responses. In this study, we developed a novel mouse model of S. aur...

www.mucosalimmunology.org

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Dane Parker @daneparkerlab.com · May 13

The virtual Staphylococcal meeting is happening July 9-10, cheap and easy way to stay up-to-date with the latest research! Over 20 great presentations! #Staphylococcus #Staphylococci
staphsymposia.org

STAPH-SYMPOSIA 2025 – Virtual Symposium on Staphylococcal Infections

staphsymposia.org

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Dane Parker @daneparkerlab.com · May 3

Reach out to your representatives to fight the govt cuts to research. ASM has made it easy for you to do so.

Bill Goldman @wgoldman1.bsky.social · May 2

The Presidential Budget Request has been released, and it details some serious cuts to scientific funding and research. Please use the link below to automatically send a letter to your Representative and Senators -- you can customize the pre-written message with your personal story.

Action Alerts

ASM is a nonprofit professional society that publishes scientific journals and advances microbiology through advocacy, global health and diversity in STEM programs.

asm.org

Reposted by Dane Parker

Denis Wirtz @deniswirtz.bsky.social · Apr 28

A huge majority of Americans (77%) oppose the cuts to medical research that the current administration has made.

(Source: Wash. Post/ABC/Ipsos poll)

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Dane Parker @daneparkerlab.com · Apr 17

Latest from the lab! We had previously shown sex differences in A. baumannii pulmonary infection. Here, we show that in human males have worse outcomes compared to females. Mice are not people! @asm.org
journals.asm.org/doi/10.1128/...

Biological sex influences severity and outcomes in Acinetobacter baumannii pneumonia | Microbiology Spectrum

Biological sex has been shown to influence the incidence and outcomes of infection. We had previously documented that in a mouse model of infection, the pathogen Acinetobacter baumannii caused more se...

journals.asm.org

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Dane Parker @daneparkerlab.com · Apr 6

Wow. Very impressive!

Dane Parker @daneparkerlab.com · Mar 7

What a waste of resources

Reposted by Dane Parker

Yosuke Kumamoto @ykumamoto.bsky.social · Feb 26

Excited to see this finally out!! We found IL-2 made by CD301b+ DCs critical for the Th2 fate decision of CD4T cells and skewing them away from the Tfh fate. They also seem to use their own CD25 to direct IL-2 to the cognate clone.
www.nature.com/articles/s41...

CD301b+ dendritic cell-derived IL-2 dictates CD4+ T helper cell differentiation - Nature Communications

A subset of migratory type 2 conventional dendritic cells marked by CD301b expression (CD301b+DC), are required specifically for the development of Th2 cells. Here authors show that at the mechanistic...

www.nature.com

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Dane Parker @daneparkerlab.com · Feb 27

Bacteria as food for macrophages!

Nature @nature.com · Feb 27

Nature research paper: Macrophages recycle phagocytosed bacteria to fuel immunometabolic responses

https://go.nature.com/3XmyOPD

Macrophages recycle phagocytosed bacteria to fuel immunometabolic responses - Nature

Phagocytosed bacteria can serve as an alternative nutrient source for macrophages, influencing their metabolic and immune responses through the recycling of microbial components, with the process regulated by nutrient-sensing mechanisms and bacterial viability.

go.nature.com

Dane Parker @daneparkerlab.com · Feb 25

RIPK3 can promote neuronal survival during viral infection by @briandaniels.bsky.social at @rutgersuniversity.bsky.social !
www.cell.com/immunity/ful...

The kinase RIPK3 promotes neuronal survival by suppressing excitatory neurotransmission during central nervous system viral infection

How innate immune signaling within neurons influences neurotransmission remains poorly understood. Estevez et al. show that the necroptotic kinase RIPK3 promotes neuronal survival during viral infecti...

www.cell.com

Dane Parker @daneparkerlab.com · Feb 25

Living with cats and dogs showed an association with MRSA infection!
pubmed.ncbi.nlm.nih.gov/39995309/

Living with dogs and cats: Is it a risk factor for community acquired methicillin-resistant Staphylococcus aureus skin and soft tissue infections in humans? - PubMed

We conclude that there is an association between human MRSA SSTIs and living with CF.

pubmed.ncbi.nlm.nih.gov

Dane Parker @daneparkerlab.com · Feb 25

Hopefully re register

Dane Parker @daneparkerlab.com · Feb 23

😳

Dane Parker @daneparkerlab.com · Feb 21

Check out my old @columbiauniversity.bsky.social colleague @adamratnermd.bsky.social on his book tour, #vaccines! Or check out his book, "Booster shots". Link here, www.amazon.com/Booster-Shot....

Emory Human Health @emorycshh.bsky.social · Feb 21

It's time for another Health Storytelling LIVE Author Q&A w/ @marynmck.bsky.social. Next up @adamratnermd.bsky.social with his vital & incredibly timely #NewBook BOOSTER SHOTS: The Urgent Lessons of #Measles and the Uncertain Future of #ChildrensHealth

➡️ 2/26 7pm ET www.youtube.com/watch?v=leKj...

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