Valentin Flury
@flurylab.bsky.social
Research Group Leader, working on epigenetic memory, chromatin (replication) and transcription at the MPI-IE.
Reposted by Valentin Flury
Congratulations to @groth-anja.bsky.social on receiving the Novo Nordisk Foundation Jacobæus Prize 🏆 we’re proud to see Anja's mentorship, leadership, & pioneering work in epigenetic cell memory getting top recognition 👏 celebrating the contributions of past & present lab members to this work too 🥳
January 14, 2026 at 8:43 PM
Congratulations to @groth-anja.bsky.social on receiving the Novo Nordisk Foundation Jacobæus Prize 🏆 we’re proud to see Anja's mentorship, leadership, & pioneering work in epigenetic cell memory getting top recognition 👏 celebrating the contributions of past & present lab members to this work too 🥳
Reposted by Valentin Flury
Fully-funded #PhD positions in #epigenetics, #biophysics & #metabolism, gene regulation, cell biology and more…
Are you already on track to start an exciting research career @maxplanck.de & @uni-freiburg.de?
This is your timeline. Apply by February 6th, 2026
www.ie-freiburg.mpg.de/apply-imprs-...
Are you already on track to start an exciting research career @maxplanck.de & @uni-freiburg.de?
This is your timeline. Apply by February 6th, 2026
www.ie-freiburg.mpg.de/apply-imprs-...
January 8, 2026 at 12:32 PM
Fully-funded #PhD positions in #epigenetics, #biophysics & #metabolism, gene regulation, cell biology and more…
Are you already on track to start an exciting research career @maxplanck.de & @uni-freiburg.de?
This is your timeline. Apply by February 6th, 2026
www.ie-freiburg.mpg.de/apply-imprs-...
Are you already on track to start an exciting research career @maxplanck.de & @uni-freiburg.de?
This is your timeline. Apply by February 6th, 2026
www.ie-freiburg.mpg.de/apply-imprs-...
Reposted by Valentin Flury
Stress controls epigenetic inheritance!
A histone ubiquitylation-based regulatory hub links stress/environmental signaling to heterochromatin self-propagation and epigenetic inheritance-reshaping how we think about development, drug resistance, and cancer
👉 nature.com/articles/s41586-025-09899-8
A histone ubiquitylation-based regulatory hub links stress/environmental signaling to heterochromatin self-propagation and epigenetic inheritance-reshaping how we think about development, drug resistance, and cancer
👉 nature.com/articles/s41586-025-09899-8
January 7, 2026 at 4:46 PM
Stress controls epigenetic inheritance!
A histone ubiquitylation-based regulatory hub links stress/environmental signaling to heterochromatin self-propagation and epigenetic inheritance-reshaping how we think about development, drug resistance, and cancer
👉 nature.com/articles/s41586-025-09899-8
A histone ubiquitylation-based regulatory hub links stress/environmental signaling to heterochromatin self-propagation and epigenetic inheritance-reshaping how we think about development, drug resistance, and cancer
👉 nature.com/articles/s41586-025-09899-8
Reposted by Valentin Flury
Happy New Year!🎉 We hope everyone has enjoyed the holidays! If you have an exciting chromatin/transcription story, or if you know someone with one, please fill out the form or get in contact with us! 😉
forms.gle/TBi38UgYxPAB...
forms.gle/TBi38UgYxPAB...
January 5, 2026 at 4:49 PM
Happy New Year!🎉 We hope everyone has enjoyed the holidays! If you have an exciting chromatin/transcription story, or if you know someone with one, please fill out the form or get in contact with us! 😉
forms.gle/TBi38UgYxPAB...
forms.gle/TBi38UgYxPAB...
Reposted by Valentin Flury
Still time to apply until January, 19th!
We are recruiting a tenure track professor in the broader area of molecular biology @zmbh.uni-heidelberg.de at Heidelberg University! www.nature.com/naturecareer... Please share and apply!
Tenure Track Professorship (W1 with Tenure Track to W3) in “Molecular Biology" (f/m/d) - Heidelberg job with Universität Heidelberg | 12850668
The Center for Molecular Biology of Heidelberg University (ZMBH) and the Faculty of Biosciences invite applications for a Tenure Track Professors...
www.nature.com
January 3, 2026 at 8:15 PM
Still time to apply until January, 19th!
Congrats to the team for such creative craft - first time winner of the Christmas Wreath-Off at @mpi-ie.bsky.social!🥳
Science off the bench! 🥳
Here's to our beautiful Christmas wreath — creatively adorned with colorful Falcon caps, mini Eppis, and, of course, our signature artistic yeast plates. 😎🎨
Here's to our beautiful Christmas wreath — creatively adorned with colorful Falcon caps, mini Eppis, and, of course, our signature artistic yeast plates. 😎🎨
December 21, 2025 at 10:34 PM
Congrats to the team for such creative craft - first time winner of the Christmas Wreath-Off at @mpi-ie.bsky.social!🥳
Happy holidays from the @flurylab.bsky.social!🎉 A year with a lot of firsts: first PhD students, first Postdoc, first grant & first farewells - and a first lab move, too! Thanks to my amazing team for the hard work & curiosity!💪🧐👥 Can't wait to tackle more firsts (& seconds) in the coming year(s)!🙌🤩
December 21, 2025 at 10:27 PM
Happy holidays from the @flurylab.bsky.social!🎉 A year with a lot of firsts: first PhD students, first Postdoc, first grant & first farewells - and a first lab move, too! Thanks to my amazing team for the hard work & curiosity!💪🧐👥 Can't wait to tackle more firsts (& seconds) in the coming year(s)!🙌🤩
Reposted by Valentin Flury
Our PhD program IMPRS-EBM of #Epigenetics, #Biophysics & #Metabolism will open for applications next week. 📢
Want to work at the forefront of epigenetic research at an MPI? Looking for a fully-funded #PhDposition at Max Planck? Here is your chance: www.ie-freiburg.mpg.de/IMPRS-PhD-Pr...
Want to work at the forefront of epigenetic research at an MPI? Looking for a fully-funded #PhDposition at Max Planck? Here is your chance: www.ie-freiburg.mpg.de/IMPRS-PhD-Pr...
December 12, 2025 at 3:51 PM
Our PhD program IMPRS-EBM of #Epigenetics, #Biophysics & #Metabolism will open for applications next week. 📢
Want to work at the forefront of epigenetic research at an MPI? Looking for a fully-funded #PhDposition at Max Planck? Here is your chance: www.ie-freiburg.mpg.de/IMPRS-PhD-Pr...
Want to work at the forefront of epigenetic research at an MPI? Looking for a fully-funded #PhDposition at Max Planck? Here is your chance: www.ie-freiburg.mpg.de/IMPRS-PhD-Pr...
Reposted by Valentin Flury
This Thursday, we’re pleased to welcome Philipp Korber.
Prof Korber leads a research group on “Nucleosome Positioning & Remodeling in Yeasts” at the @bmc-lmu.bsky.social in Munich. His work has identified ATP-dependent chromatin remodelers as major determinants of nucleosome positioning.
Join us!
Prof Korber leads a research group on “Nucleosome Positioning & Remodeling in Yeasts” at the @bmc-lmu.bsky.social in Munich. His work has identified ATP-dependent chromatin remodelers as major determinants of nucleosome positioning.
Join us!
November 18, 2025 at 11:12 AM
This Thursday, we’re pleased to welcome Philipp Korber.
Prof Korber leads a research group on “Nucleosome Positioning & Remodeling in Yeasts” at the @bmc-lmu.bsky.social in Munich. His work has identified ATP-dependent chromatin remodelers as major determinants of nucleosome positioning.
Join us!
Prof Korber leads a research group on “Nucleosome Positioning & Remodeling in Yeasts” at the @bmc-lmu.bsky.social in Munich. His work has identified ATP-dependent chromatin remodelers as major determinants of nucleosome positioning.
Join us!
Reposted by Valentin Flury
Wonderful opportunity to work with Martin Howard and my group trying to understand how chromatin influences gene transcription and expression. Integration of theory, modelling, and experimentation. Come and join the team!
Please repost!
jobs.jic.ac.uk/Details.asp?...
Please repost!
jobs.jic.ac.uk/Details.asp?...
John Innes Centre
jobs.jic.ac.uk
October 8, 2025 at 9:04 AM
Wonderful opportunity to work with Martin Howard and my group trying to understand how chromatin influences gene transcription and expression. Integration of theory, modelling, and experimentation. Come and join the team!
Please repost!
jobs.jic.ac.uk/Details.asp?...
Please repost!
jobs.jic.ac.uk/Details.asp?...
Reposted by Valentin Flury
Very sad news, John Gurdon has died.
A developmental biologist's developmental biologist, Nobel prize winner
His work is the foundation of much of today's dev & stem cell bio.
An inspiration to many, including me. Always asking questions & wanting the answers
www.magd.cam.ac.uk/news/profess...
A developmental biologist's developmental biologist, Nobel prize winner
His work is the foundation of much of today's dev & stem cell bio.
An inspiration to many, including me. Always asking questions & wanting the answers
www.magd.cam.ac.uk/news/profess...
Professor Sir John Gurdon FRS (1933-2025) | Magdalene College
Magdalene College is deeply saddened to announce the death of Professor Sir John Gurdon FRS, who served as Master of the College from 1995 to 2002.
www.magd.cam.ac.uk
October 7, 2025 at 4:02 PM
Very sad news, John Gurdon has died.
A developmental biologist's developmental biologist, Nobel prize winner
His work is the foundation of much of today's dev & stem cell bio.
An inspiration to many, including me. Always asking questions & wanting the answers
www.magd.cam.ac.uk/news/profess...
A developmental biologist's developmental biologist, Nobel prize winner
His work is the foundation of much of today's dev & stem cell bio.
An inspiration to many, including me. Always asking questions & wanting the answers
www.magd.cam.ac.uk/news/profess...
It has been a lot of fun to present our research focus and get to know the @gfgenetik.bsky.social! Thank you so much for having me and organising this great symposium! Looking forward to the next one!
Amazing 2. day at the GfG ‘Epigenetics & Chromatin’ symposium. Fantastic flash talks, a great first poster session and many memorable talks: among others @erhardtlab.bsky.social, @rodvilla.bsky.social, @thebraunlab.bsky.social, @flurylab.bsky.social, Ehrenhofer-Murray, Liefke, Heun, Imhof & Brehm.
September 28, 2025 at 2:38 PM
It has been a lot of fun to present our research focus and get to know the @gfgenetik.bsky.social! Thank you so much for having me and organising this great symposium! Looking forward to the next one!
Reposted by Valentin Flury
This one feels special: our latest work on subtelomeric heterochromatin is now on www.biorxiv.org/content/10.1....
This story was driven by the virtuoso PhD work of Agnisrota Mazumder @agnisrota.bsky.social, co-mentored with @al-sadylab.bsky.social, and grew out of our #MSCA Cell2Cell network.
This story was driven by the virtuoso PhD work of Agnisrota Mazumder @agnisrota.bsky.social, co-mentored with @al-sadylab.bsky.social, and grew out of our #MSCA Cell2Cell network.
Discrete Subdomains Establish Epigenetic Diversity in Subtelomeric Heterochromatin
Subtelomeres are imperfect repeats adjacent to telomeres that are repressed by heterochromatin. Although essential for genome integrity, their repetitive nature has thwarted dissection of local hetero...
www.biorxiv.org
September 27, 2025 at 6:55 AM
This one feels special: our latest work on subtelomeric heterochromatin is now on www.biorxiv.org/content/10.1....
This story was driven by the virtuoso PhD work of Agnisrota Mazumder @agnisrota.bsky.social, co-mentored with @al-sadylab.bsky.social, and grew out of our #MSCA Cell2Cell network.
This story was driven by the virtuoso PhD work of Agnisrota Mazumder @agnisrota.bsky.social, co-mentored with @al-sadylab.bsky.social, and grew out of our #MSCA Cell2Cell network.
Reposted by Valentin Flury
🚀 Our new paper is out @natmethods.nature.com!
Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.
🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/
Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.
🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/
September 22, 2025 at 6:27 PM
🚀 Our new paper is out @natmethods.nature.com!
Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.
🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/
Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.
🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/
Reposted by Valentin Flury
I am excited to announce that we are looking for a Lab Manager @fmiscience.bsky.social in Basel. If you want to be part of a growing team investigating development and tissue formation, and are enthusiastic about helping set up a new lab, please check out the role:
www.fmi.ch/education-ca...
www.fmi.ch/education-ca...
September 14, 2025 at 11:46 AM
I am excited to announce that we are looking for a Lab Manager @fmiscience.bsky.social in Basel. If you want to be part of a growing team investigating development and tissue formation, and are enthusiastic about helping set up a new lab, please check out the role:
www.fmi.ch/education-ca...
www.fmi.ch/education-ca...
Reposted by Valentin Flury
We are hiring-join us!
🚨 We're hiring, please share! The FMI seeks a tenure-track Group Leader (Assistant Prof) in Structural Biology 🔬
Innovative scientists in genome regulation, RNA metabolism, or protein homeostasis—especially using cutting-edge approaches—apply now at www.fmi.ch/education-ca...
Innovative scientists in genome regulation, RNA metabolism, or protein homeostasis—especially using cutting-edge approaches—apply now at www.fmi.ch/education-ca...
September 8, 2025 at 10:31 AM
We are hiring-join us!
Reposted by Valentin Flury
Massive congratulations to @canaztekin.bsky.social for being awarded an ERC Starting Grant @erc.europa.eu ! 🎉 His "Signal to Regeneration" (SigReg) project will explore the potential of limb regeneration in mammals.
Read more and watch Can introduce his project: s.gwdg.de/cLAmJE
Read more and watch Can introduce his project: s.gwdg.de/cLAmJE
September 4, 2025 at 12:56 PM
Massive congratulations to @canaztekin.bsky.social for being awarded an ERC Starting Grant @erc.europa.eu ! 🎉 His "Signal to Regeneration" (SigReg) project will explore the potential of limb regeneration in mammals.
Read more and watch Can introduce his project: s.gwdg.de/cLAmJE
Read more and watch Can introduce his project: s.gwdg.de/cLAmJE
What a special moment!🙌🙌🙌
I am also very happy to share this good news my colleague @flurylab.bsky.social @mpi-ie.bsky.social 🥂🥂
🎊 Congratulations to Juliane Glaser (@julianeg.bsky.social) and Valentin Flury (@flurylab.bsky.social) on being awarded each an @erc.europa.eu Starting Grant! – #ERCStG
www.ie-freiburg.mpg.de/6057908/2025...
www.ie-freiburg.mpg.de/6057908/2025...
September 4, 2025 at 7:22 PM
What a special moment!🙌🙌🙌
Excited and very grateful to announce that I have been awarded an ERC Starting Grant by @erc.europa.eu! 🎉 This is a fantastic opportunity to further build my team at the Max Planck Institute of Immunobiology and Epigenetics (@mpi-ie.bsky.social) exploring new grounds in fundamental research:
📣 The ERC Starting Grant call results are out!
Find out which early-career researchers will receive funding this year, what they will be investigating, where they will be based... plus lots of other #ERCStG facts & figures for 2025!
➡️ buff.ly/IsafuFh
#FrontierResearch 🇪🇺#EUfunded #HorizonEurope
Find out which early-career researchers will receive funding this year, what they will be investigating, where they will be based... plus lots of other #ERCStG facts & figures for 2025!
➡️ buff.ly/IsafuFh
#FrontierResearch 🇪🇺#EUfunded #HorizonEurope
September 4, 2025 at 7:19 PM
Excited and very grateful to announce that I have been awarded an ERC Starting Grant by @erc.europa.eu! 🎉 This is a fantastic opportunity to further build my team at the Max Planck Institute of Immunobiology and Epigenetics (@mpi-ie.bsky.social) exploring new grounds in fundamental research:
Reposted by Valentin Flury
🥳 Thrilled to share that our lab has been awarded an ERC StGrant for our project SigReg: Signal to Regeneration!
How can we unlock limb regeneration in adult mammals?
It’s time to apply what we learned from 🐸 ➡️ 🐭
Thank you @erc.europa.eu for supporting ambitious science!!!
How can we unlock limb regeneration in adult mammals?
It’s time to apply what we learned from 🐸 ➡️ 🐭
Thank you @erc.europa.eu for supporting ambitious science!!!
Massive congratulations to @canaztekin.bsky.social for being awarded an ERC Starting Grant @erc.europa.eu ! 🎉 His "Signal to Regeneration" (SigReg) project will explore the potential of limb regeneration in mammals.
Read more and watch Can introduce his project: s.gwdg.de/cLAmJE
Read more and watch Can introduce his project: s.gwdg.de/cLAmJE
September 4, 2025 at 1:27 PM
🥳 Thrilled to share that our lab has been awarded an ERC StGrant for our project SigReg: Signal to Regeneration!
How can we unlock limb regeneration in adult mammals?
It’s time to apply what we learned from 🐸 ➡️ 🐭
Thank you @erc.europa.eu for supporting ambitious science!!!
How can we unlock limb regeneration in adult mammals?
It’s time to apply what we learned from 🐸 ➡️ 🐭
Thank you @erc.europa.eu for supporting ambitious science!!!
Reposted by Valentin Flury
We have lift off!! 🚀 Yesterday was the official opening of EpiC! The DNRF Center for Epigenetic Cell Memory at the Danish Cancer Institute!
Our EpiC team with director Anja Groth @groth-anja.bsky.social, were joined by Jesper Fisker, CEO @cancer.dk & Niels Mejlgaar, CEO @dg.dk to celebrate 🎉
Our EpiC team with director Anja Groth @groth-anja.bsky.social, were joined by Jesper Fisker, CEO @cancer.dk & Niels Mejlgaar, CEO @dg.dk to celebrate 🎉
August 28, 2025 at 5:35 PM
We have lift off!! 🚀 Yesterday was the official opening of EpiC! The DNRF Center for Epigenetic Cell Memory at the Danish Cancer Institute!
Our EpiC team with director Anja Groth @groth-anja.bsky.social, were joined by Jesper Fisker, CEO @cancer.dk & Niels Mejlgaar, CEO @dg.dk to celebrate 🎉
Our EpiC team with director Anja Groth @groth-anja.bsky.social, were joined by Jesper Fisker, CEO @cancer.dk & Niels Mejlgaar, CEO @dg.dk to celebrate 🎉
Last week, we bid farewell to our Summer student Jean.🍹👋 It was great having you in the lab and we wish you all the best finishing your studies!🍀 See you soon!🥳
August 29, 2025 at 10:32 AM
Last week, we bid farewell to our Summer student Jean.🍹👋 It was great having you in the lab and we wish you all the best finishing your studies!🍀 See you soon!🥳
Reposted by Valentin Flury
It is not always safe to repair DNA Damage. Sometimes, cells "just bypass it".
During DNA replication, repair of lesions on DNA can be dangerous. Cells instead "tolerate" DNA damage and focus on finishing replication.
Read our review and find out why and how: doi.org/10.1016/j.ti...
During DNA replication, repair of lesions on DNA can be dangerous. Cells instead "tolerate" DNA damage and focus on finishing replication.
Read our review and find out why and how: doi.org/10.1016/j.ti...
August 22, 2025 at 11:48 AM
It is not always safe to repair DNA Damage. Sometimes, cells "just bypass it".
During DNA replication, repair of lesions on DNA can be dangerous. Cells instead "tolerate" DNA damage and focus on finishing replication.
Read our review and find out why and how: doi.org/10.1016/j.ti...
During DNA replication, repair of lesions on DNA can be dangerous. Cells instead "tolerate" DNA damage and focus on finishing replication.
Read our review and find out why and how: doi.org/10.1016/j.ti...
Reposted by Valentin Flury
📢 Excited to share my World View article, just published in @NatureSMB, where I reflect on returning to Czechia and building research group grounded in collaboration🤝, resilience and curiosity💡. www.nature.com/articles/s41...
https://nature.com/articles/s4159…
August 7, 2025 at 5:28 PM
📢 Excited to share my World View article, just published in @NatureSMB, where I reflect on returning to Czechia and building research group grounded in collaboration🤝, resilience and curiosity💡. www.nature.com/articles/s41...
Reposted by Valentin Flury
Director at Max Planck - a unique position! The Open Call for Expressions of Interest in Max Planck Directorships is open now and can be submitted by the 31st of October 2025. ➡️ mpg.de/directors - Please share the Open Call among potential candidates.
August 1, 2025 at 9:06 AM
Director at Max Planck - a unique position! The Open Call for Expressions of Interest in Max Planck Directorships is open now and can be submitted by the 31st of October 2025. ➡️ mpg.de/directors - Please share the Open Call among potential candidates.