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Garrett Beeghly, PhD

@gbeeghly.bsky.social

1.2K followers 410 following 92 posts

Postdoc in the Radisic Lab at the University of Toronto and University Health Network. Engineering tissues to understand health and disease. Baker, hiker, cat dad. He/him. 🏳️‍🌈 https://gbeeghly.github.io/

gbeeghly.github.io

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Garrett Beeghly, PhD @gbeeghly.bsky.social · Apr 7

Preprint alert! Excited to share this manuscript from my PhD which aims to answer an age-old question. Does size matter? For fat cells, or adipocytes, the answer seems to be yes. We found that larger adipocytes promote aggressive behavior in breast cancer cells. 1/5 www.biorxiv.org/content/10.1...

Hypertrophic adipocytes increase extracellular vesicle-mediated lipid release and reprogram breast cancer cell metabolism

Obesity worsens cancer-specific survival and all-cause mortality for women diagnosed with breast cancer. Rich in adipose tissue, the breast exhibits increased adipocyte size in obesity, which correlat...

www.biorxiv.org

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Reposted by Garrett Beeghly, PhD

Nature Reviews Bioengineering @natrevbioeng.nature.com · 14d

Tumour heterogeneity comes at different length scales.This article classifies regulators of cancer into tumour-cell-intrinsic, tissue-microenvironment and organism-level sources, describing engineering strategies to measure and analyse these factors:

Measuring and modelling tumour heterogeneity across scales - Nature Reviews Bioengineering

Heterogeneity constitutes a critical barrier to treating cancer. This Review discusses the biological and physical sources of heterogeneity across length scales, encompassing tumour-cell-intrinsic, tissue-microenvironment and organism-level sources, and how engineering strategies can improve our understanding of these phenomena.

go.nature.com

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Garrett Beeghly, PhD @gbeeghly.bsky.social · Sep 2

Unfortunately, I think it is for desktop only but maybe you can find something equivalent for mobile 😬

Garrett Beeghly, PhD @gbeeghly.bsky.social · Sep 1

I found a custom ublock origin filter that gets rid of most of the ads on YouTube! I can’t imagine actually sitting through the number of them on most videos

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Garrett Beeghly, PhD @gbeeghly.bsky.social · Aug 31

On a quest to make my own yogurt and cottage cheese… and all I can think is how useful it would be to have a hot plate and stir bar to prevent milk from burning. Why doesn’t this exist? #ScientistsWhoCook

Garrett Beeghly, PhD @gbeeghly.bsky.social · Aug 21

Congrats Jenn!

Garrett Beeghly, PhD @gbeeghly.bsky.social · Aug 17

It was not an easy process getting back to Toronto this weekend and I ended up getting a last minute flight with Flair... Hope you can get it sorted out!

Garrett Beeghly, PhD @gbeeghly.bsky.social · Jul 27

Yes, looking forward to seeing your future work too!

Garrett Beeghly, PhD @gbeeghly.bsky.social · Jul 27

Thank you, Adeel! 🙌

Garrett Beeghly, PhD @gbeeghly.bsky.social · Jul 16

Excited to start my postdoctoral training @utoronto.ca and @uhn.ca this week! I will work with Dr. Milica Radisic who is a leader in developing organ-on-a-chip technologies and engineering functional microtissues. Glad to be in a new environment committed to funding the future of science 🇨🇦🔬

Photo of the Terrence Donnelly Centre for Cellular and Biomolecular Research against a blue sky at the University of Toronto

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Garrett Beeghly, PhD @gbeeghly.bsky.social · Jun 24

Congrats Ya’el! So happy for you!

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Garrett Beeghly, PhD @gbeeghly.bsky.social · Jun 11

Congrats! Amazing news 🥳

Garrett Beeghly, PhD @gbeeghly.bsky.social · May 31

Congrats, Pilar! So great to see some good news!

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Garrett Beeghly, PhD @gbeeghly.bsky.social · May 21

Cali approves of this important breakthrough in science! #catsky #catsofbluesky #calico #scisky

A picture of my cat, Cali, looking thoughtful with her two front paws crossed

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Garrett Beeghly, PhD @gbeeghly.bsky.social · May 21

The funding situation is rough! Hopefully things will turn around (this is what I’m telling myself)

Garrett Beeghly, PhD @gbeeghly.bsky.social · May 21

Congrats, Johanna! Well deserved!

Garrett Beeghly, PhD @gbeeghly.bsky.social · May 20

Had a great visit to Stanford last week and managed to squeeze in a visit to Half Moon Bay! Glad to have soaked up a little extra California sun ☀️ #blueskyartshow #nature #photography

A photograph of a sunny Half Moon Bay in California with waves crashing against the rocky coast and a wooden fence in the foreground

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Reposted by Garrett Beeghly, PhD

Nate Richbourg @nrichbourg.bsky.social · May 19

I am incredibly excited to share that I will be starting as an Assistant Professor of Biomedical Engineering in the CBE Department at FAMU-FSU College of Engineering this fall! Ready for some Florida sunshine 😁

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Garrett Beeghly, PhD @gbeeghly.bsky.social · May 20

Congrats, Nate! This is amazing news! I'm so happy for you! ☀️

Reposted by Garrett Beeghly, PhD

Monica Ohnsorg, Ph.D. @monicaohnsorg.bsky.social · May 20

I am THRILLED to officially announce that I have accepted a position as an Assistant Professor of Biomedical Engineering at the University of Wisconsin-Madison starting January 2026! My lab will use expertise in polymer science, biomaterials, and ECM engineering study osteochondral disease! 🦡 🔬🧪🧫 🦴

Me holding a scarf that says biomedical engineering while wearing a UW-Madison branded winter hat and quarter zip

Me popping a bottle of champagne while wearing UW-Madison quarter-zip standing on a balcony in front of the Flatirons

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Reposted by Garrett Beeghly, PhD

Alondra Nelson @alondra.bsky.social · May 14

Science Magazine gets it wrong. 🧵

Kai Kupferschmidt @kakape.bsky.social · May 13

“Her departure, which she announced this morning in an essay in Time, is believed to be the first time in the agency’s 75-year history that a member of the 24-person board resigned over a policy disagreement with an administration”
@policyhound.bsky.social on Alondra Nelson’s bombshell resignation 🧪

NSF board member resigns in protest of Trump policies at agency

Alondra Nelson fingers DOGE in taking an unprecedented step

www.science.org

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Garrett Beeghly, PhD @gbeeghly.bsky.social · Apr 29

Congrats Jason!

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Garrett Beeghly, PhD @gbeeghly.bsky.social · Apr 27

Had a great time working with @natrevbioeng.nature.com to put this review together! Biophysical cues integrate across length scales (molecular, cellular, tissue level, organismal) to drive cancer outcomes. Bioengineers have the tools to measure and model these factors in isolation 🛠️🔬

Nature Reviews Bioengineering @natrevbioeng.nature.com · Apr 27

Measuring and modelling tumour heterogeneity across scales - Nature Reviews Bioengineering

go.nature.com

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Garrett Beeghly, PhD @gbeeghly.bsky.social · Apr 26

Overdue debut of my cat Cali on Bluesky for this spring #caturday

A picture of my calico cat looking out of a window.

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Garrett Beeghly, PhD @gbeeghly.bsky.social · Apr 26

#BabysFirstConfocal

Garrett Beeghly, PhD @gbeeghly.bsky.social · Apr 7

Ultimately, our findings suggest that larger adipocytes constitute a distinct cell population within mammary adipose tissue and increase lipid transfer to invading cancer cells. As a result, we propose that adipocyte size could serve as a prognostic biomarker for breast cancer patients. 5/5